ES2103236A1 - Albumina humana terapeutica con baja capacidad para la fijacion de aluminio. - Google Patents

Albumina humana terapeutica con baja capacidad para la fijacion de aluminio.

Info

Publication number
ES2103236A1
ES2103236A1 ES09600200A ES9600200A ES2103236A1 ES 2103236 A1 ES2103236 A1 ES 2103236A1 ES 09600200 A ES09600200 A ES 09600200A ES 9600200 A ES9600200 A ES 9600200A ES 2103236 A1 ES2103236 A1 ES 2103236A1
Authority
ES
Spain
Prior art keywords
human albumin
binding activity
therapeutic human
low aluminium
albumin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES09600200A
Other languages
English (en)
Other versions
ES2103236B1 (es
Inventor
Debart Pere Ristol
Torrecillas David Camarero
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Grifols SA
Original Assignee
Grifols SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8293596&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2103236(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Grifols SA filed Critical Grifols SA
Priority to ES09600200A priority Critical patent/ES2103236B1/es
Priority to DK96500164T priority patent/DK0787498T3/da
Priority to PT96500164T priority patent/PT787498E/pt
Priority to DE0787498T priority patent/DE787498T1/de
Priority to DE04000874T priority patent/DE04000874T1/de
Priority to EP96500164A priority patent/EP0787498B1/en
Priority to EP04000874A priority patent/EP1413312A3/en
Priority to AT96500164T priority patent/ATE269717T1/de
Priority to ES04000874T priority patent/ES2220256T1/es
Priority to DE69632771T priority patent/DE69632771T2/de
Priority to ES96500164T priority patent/ES2220967T3/es
Priority to HU9603601A priority patent/HUP9603601A3/hu
Priority to CZ19976A priority patent/CZ289782B6/cs
Priority to ARP970100050A priority patent/AR005374A1/es
Priority to SK35-97A priority patent/SK284297B6/sk
Priority to MXPA/A/1997/000617A priority patent/MXPA97000617A/es
Priority to UY24448A priority patent/UY24448A1/es
Priority to US08/788,275 priority patent/US5846930A/en
Priority to JP9013792A priority patent/JP3054371B2/ja
Publication of ES2103236A1 publication Critical patent/ES2103236A1/es
Publication of ES2103236B1 publication Critical patent/ES2103236B1/es
Application granted granted Critical
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/38—Albumins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame

Abstract

ALBUMINA HUMANA TERAPEUTICA CON BAJA CAPACIDAD PARA LA FIJACION DE ALUMINIO. SE DA A CONOCER UNA ALBUMINA HUMANA TERAPEUTICA CON MUY BAJA CAPACIDAD DE ABSORCION DE ALUMINIO, DURANTE EL TIEMPO DE ALMACENAMIENTO EN ENVASE DE: VIDRIO, EN LA QUE LA COMPOSICION FINAL DE LA SOLUCION DE ALBUMINA AJUSTADA DE ESTABILIZANTES E ISOTONIA A LA CONCENTRACION DEL 5,20 O 25% DE PROTEINA EN MEDIO ACUOSO, PREFERENTEMENTE, O A CUALQUIER OTRA CONCENTRACION TERAPEUTICA ACEPTABLE POR VIA INTRAVENOSA, PRESENTA UN CONTENIDO DE CITRATO EN LA COMPOSICION FINAL DE ALBUMINA IGUAL O INFERIOR A 0,5 MM (MILIMOLAR) Y, PREFERENTEMENTE, INFERIOR A 0,037 MM (MILIMOLAR).
ES09600200A 1996-01-30 1996-01-30 Albumina humana terapeutica con baja capacidad para la fijacion de aluminio. Expired - Fee Related ES2103236B1 (es)

Priority Applications (19)

Application Number Priority Date Filing Date Title
ES09600200A ES2103236B1 (es) 1996-01-30 1996-01-30 Albumina humana terapeutica con baja capacidad para la fijacion de aluminio.
ES96500164T ES2220967T3 (es) 1996-01-30 1996-12-18 Albumina humana terapeutica con baja capacidad para la fijacion de aliuminio.
PT96500164T PT787498E (pt) 1996-01-30 1996-12-18 Albumina humana terapeutica com uma baixa capacidade de ligacao ao aluminio
DE0787498T DE787498T1 (de) 1996-01-30 1996-12-18 Menschliche therapeutische Albumin mit niedriger Aluminiumbindungsfähigkeit
DE04000874T DE04000874T1 (de) 1996-01-30 1996-12-18 Menschliches therapeutisches Albumin mit niedriger Aluminiumbindungsfähigkeit
EP96500164A EP0787498B1 (en) 1996-01-30 1996-12-18 Therapeutic human albumin having a low aluminium binding capacity
EP04000874A EP1413312A3 (en) 1996-01-30 1996-12-18 Therapeutic human albumin having a low aluminium binding activity
AT96500164T ATE269717T1 (de) 1996-01-30 1996-12-18 Menschliche therapeutische albumin mit niedriger aluminiumbindungsfähigkeit
ES04000874T ES2220256T1 (es) 1996-01-30 1996-12-18 Albumina humana terapeutica con baja actividad para la fijacion de aluminio.
DE69632771T DE69632771T2 (de) 1996-01-30 1996-12-18 Menschliche therapeutische Albumin mit niedriger Aluminiumbindungsfähigkeit
DK96500164T DK0787498T3 (da) 1996-01-30 1996-12-18 Terapeutisk humant albumin med en lav aluminiumbindingskapacitet
HU9603601A HUP9603601A3 (en) 1996-01-30 1996-12-27 Therapeutic human albumin having a low aluminium binding capacity
CZ19976A CZ289782B6 (cs) 1996-01-30 1997-01-03 Farmaceutický prostředek obsahující lidský albumin
ARP970100050A AR005374A1 (es) 1996-01-30 1997-01-07 Albumina humana terapeutica con baja capacidad para la fijacion de aluminio
SK35-97A SK284297B6 (sk) 1996-01-30 1997-01-10 Farmaceutický prostriedok obsahujúci ľudský albumín
MXPA/A/1997/000617A MXPA97000617A (es) 1996-01-30 1997-01-23 Albumina humana terapeutica con baja capacidadpara la fijacion de aluminio
UY24448A UY24448A1 (es) 1996-01-30 1997-01-24 Albumina humana terapeutica con baja capacidad para la fijacion de aluminio
US08/788,275 US5846930A (en) 1996-01-30 1997-01-24 Therapeutic human albumin having a low aluminium binding capacity
JP9013792A JP3054371B2 (ja) 1996-01-30 1997-01-28 アルミニウム結合能の低い治療用ヒトアルブミン

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES09600200A ES2103236B1 (es) 1996-01-30 1996-01-30 Albumina humana terapeutica con baja capacidad para la fijacion de aluminio.

Publications (2)

Publication Number Publication Date
ES2103236A1 true ES2103236A1 (es) 1997-09-01
ES2103236B1 ES2103236B1 (es) 1998-04-16

Family

ID=8293596

Family Applications (3)

Application Number Title Priority Date Filing Date
ES09600200A Expired - Fee Related ES2103236B1 (es) 1996-01-30 1996-01-30 Albumina humana terapeutica con baja capacidad para la fijacion de aluminio.
ES96500164T Expired - Lifetime ES2220967T3 (es) 1996-01-30 1996-12-18 Albumina humana terapeutica con baja capacidad para la fijacion de aliuminio.
ES04000874T Pending ES2220256T1 (es) 1996-01-30 1996-12-18 Albumina humana terapeutica con baja actividad para la fijacion de aluminio.

Family Applications After (2)

Application Number Title Priority Date Filing Date
ES96500164T Expired - Lifetime ES2220967T3 (es) 1996-01-30 1996-12-18 Albumina humana terapeutica con baja capacidad para la fijacion de aliuminio.
ES04000874T Pending ES2220256T1 (es) 1996-01-30 1996-12-18 Albumina humana terapeutica con baja actividad para la fijacion de aluminio.

Country Status (13)

Country Link
US (1) US5846930A (es)
EP (2) EP0787498B1 (es)
JP (1) JP3054371B2 (es)
AR (1) AR005374A1 (es)
AT (1) ATE269717T1 (es)
CZ (1) CZ289782B6 (es)
DE (2) DE787498T1 (es)
DK (1) DK0787498T3 (es)
ES (3) ES2103236B1 (es)
HU (1) HUP9603601A3 (es)
PT (1) PT787498E (es)
SK (1) SK284297B6 (es)
UY (1) UY24448A1 (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT403989B (de) * 1996-09-16 1998-07-27 Immuno Ag Verfahren zur herstellung eines plasmaprotein-hältigen arzneimittels
EP0995419B1 (en) 1998-10-21 2005-12-21 Nipro Corporation Method for producing a plastic vessel containing an albumin preparation
US6693173B2 (en) * 2000-12-26 2004-02-17 Alpha Therapeutic Corporation Method to remove citrate and aluminum from proteins
GB0117879D0 (en) * 2001-07-21 2001-09-12 Common Services Agency Storage of liquid compositions
JP2003040798A (ja) * 2001-07-26 2003-02-13 Nihon Pharmaceutical Co Ltd 低アルミニウム含有アルブミン製剤およびその製造法
US6718735B2 (en) * 2002-03-19 2004-04-13 Baxter International Inc. Albumin in a flexible polymeric container
ES2221817B1 (es) 2004-07-26 2005-10-01 Probitas Pharma, S.A. "soluciones de albumina humana terapeutica con baja actividad del activador de precalicreina (pka) y procedimiento de obtencion de las mismas".
ES2294976B1 (es) 2007-11-12 2008-12-16 Grifols, S.A. "procedimiento de obtencion de albumina humana de alta eficacia para su uso en terapia de detoxificacion".
US11739166B2 (en) 2020-07-02 2023-08-29 Davol Inc. Reactive polysaccharide-based hemostatic agent

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0452753A1 (en) * 1990-04-19 1991-10-23 Bayer Corporation Essentially monomeric normal serum albumin (human)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE405549B (sv) * 1975-10-09 1978-12-18 Pharmacia Fine Chemicals Ab Forfarande for isolering av albumin ur plasmaprodukter genom kromatografisk fraktionering
SE500110C2 (sv) * 1989-06-27 1994-04-18 Kabi Pharmacia Ab Sätt att rena ett protein från därtill bundna flervärda metalljoner
US5561115A (en) * 1994-08-10 1996-10-01 Bayer Corporation Low temperature albumin fractionation using sodium caprylate as a partitioning agent
AT403989B (de) * 1996-09-16 1998-07-27 Immuno Ag Verfahren zur herstellung eines plasmaprotein-hältigen arzneimittels

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0452753A1 (en) * 1990-04-19 1991-10-23 Bayer Corporation Essentially monomeric normal serum albumin (human)

Also Published As

Publication number Publication date
DK0787498T3 (da) 2004-10-11
ES2220967T3 (es) 2004-12-16
CZ697A3 (en) 1997-08-13
HU9603601D0 (en) 1997-02-28
ES2103236B1 (es) 1998-04-16
EP1413312A2 (en) 2004-04-28
HUP9603601A3 (en) 1998-01-28
PT787498E (pt) 2004-10-29
CZ289782B6 (cs) 2002-04-17
EP1413312A3 (en) 2004-09-01
JPH09221431A (ja) 1997-08-26
UY24448A1 (es) 1997-02-18
ATE269717T1 (de) 2004-07-15
SK3597A3 (en) 1997-08-06
EP0787498B1 (en) 2004-06-23
AR005374A1 (es) 1999-04-28
EP0787498A3 (en) 1998-10-21
JP3054371B2 (ja) 2000-06-19
DE69632771T2 (de) 2005-07-07
HUP9603601A2 (en) 1997-08-28
ES2220256T1 (es) 2004-12-16
DE69632771D1 (de) 2004-07-29
US5846930A (en) 1998-12-08
EP0787498A2 (en) 1997-08-06
DE787498T1 (de) 1999-05-20
SK284297B6 (sk) 2005-01-03
MX9700617A (es) 1997-07-31

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