ES2102081T3 - Inductores de parainmunidad multipotentes basados en combinaciones de componentes de poxvirus, metodos para preparar los mismos, y su uso como farmacos. - Google Patents
Inductores de parainmunidad multipotentes basados en combinaciones de componentes de poxvirus, metodos para preparar los mismos, y su uso como farmacos.Info
- Publication number
- ES2102081T3 ES2102081T3 ES94103047T ES94103047T ES2102081T3 ES 2102081 T3 ES2102081 T3 ES 2102081T3 ES 94103047 T ES94103047 T ES 94103047T ES 94103047 T ES94103047 T ES 94103047T ES 2102081 T3 ES2102081 T3 ES 2102081T3
- Authority
- ES
- Spain
- Prior art keywords
- drugs
- preparing
- combinations
- paramunity
- powerful
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/275—Poxviridae, e.g. avipoxvirus
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/24011—Poxviridae
- C12N2710/24022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/24011—Poxviridae
- C12N2710/24111—Orthopoxvirus, e.g. vaccinia virus, variola
- C12N2710/24122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Virology (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biophysics (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Epidemiology (AREA)
- Biotechnology (AREA)
- Mycology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Engineering & Computer Science (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
SE DESCRIBEN INDUCTORES DE PARAINMUNIDAD MULTIPOTENTE SOBRE LA BASE DE COMBINACIONES DE COMPONENTES DE VIRUS DE BOLSILLO, QUE SE DERIVAN DE LOS VIRUS DE BOLSILLO DIFERENTES CON PROPIEDADES DE PARAINMUNIZACION Y CON REFERENCIA A SU POTENCIA Y A SUS ACTIVIDADES, QUE PARTICIPAN EN LA PARAINMUNIZACION, SE HAN MEJORADO EN RELACION A LOS INDUCTORES DE PARAINMUNIDAD CONOCIDOS. LA INVENCION SE REFIERE ADEMAS A UN PROCEDIMIENTO DE ESTOS INDUCTORES DE PARAINMUNIDAD MULTIPOTENTE ASI COMO SU UTILIZACION COMO MEDICAMENTO.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE4405841A DE4405841C1 (de) | 1994-02-23 | 1994-02-23 | Multipotente Paramunitätsinducer auf der Basis von Kombinationen von Pockenviruskomponenten, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2102081T3 true ES2102081T3 (es) | 1997-07-16 |
Family
ID=6511005
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES94103047T Expired - Lifetime ES2102081T3 (es) | 1994-02-23 | 1994-03-01 | Inductores de parainmunidad multipotentes basados en combinaciones de componentes de poxvirus, metodos para preparar los mismos, y su uso como farmacos. |
Country Status (20)
Country | Link |
---|---|
US (1) | US6805870B1 (es) |
EP (1) | EP0669133B1 (es) |
JP (1) | JP2873880B2 (es) |
KR (1) | KR100196204B1 (es) |
CN (1) | CN1142187A (es) |
AT (1) | ATE153242T1 (es) |
AU (1) | AU690625B2 (es) |
BR (1) | BR9506882A (es) |
CA (1) | CA2182207C (es) |
DE (2) | DE4405841C1 (es) |
DK (1) | DK0669133T3 (es) |
ES (1) | ES2102081T3 (es) |
FI (1) | FI116557B (es) |
GR (1) | GR3023508T3 (es) |
HU (1) | HU220972B1 (es) |
NO (1) | NO319250B1 (es) |
NZ (1) | NZ278079A (es) |
PL (1) | PL182132B1 (es) |
SI (1) | SI0669133T1 (es) |
WO (1) | WO1995022978A1 (es) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE59712852D1 (de) * | 1996-02-28 | 2007-07-19 | Bayer Healthcare Ag | Parapockenviren, die fremd-dna enthalten, ihre herstellung und ihre verwendung in impfstoffen |
HU224308B1 (hu) * | 1996-04-15 | 2005-07-28 | Anton Mayr | Attenuált, nem immunogén poxvírusokból vagy parapoxvírusokból származó multipotens parapox immunitás-inducerek alkalmazása gyógyszerkészítmények előállítására |
JPH1192390A (ja) * | 1997-09-17 | 1999-04-06 | Natl Fedelation Of Agricult Coop Assoc | ストレス状態改善剤 |
AU5036899A (en) | 1998-06-26 | 2000-01-17 | Aventis Pasteur | Use of poxviruses as enhancer of specific immunity |
DE19922407A1 (de) * | 1999-05-14 | 2000-11-16 | Bayer Ag | Organ-, gewebs- und zellspezifisches Immuntherapeutikum für chronische virale Infektionen, sowie entzündliche, degenerative und proliferative Erkrankungen insbesondere der Leber sowie Krebs auf der Basis von rekombinantem Parapoxvirus |
DK1180155T3 (da) * | 1999-05-28 | 2009-02-16 | Helmholtz Zentrum Muenchen | Vektor til integration af heterologe sekvenser i poxvirale genomer |
US6682743B2 (en) * | 2000-03-14 | 2004-01-27 | Bavarian Nordic A/S | Altered strain of the modified vaccinia virus ankara (MVA) |
EP1303286B1 (de) * | 2000-07-11 | 2006-04-26 | Bayer HealthCare AG | Verwendung von stämmen des parapoxvirus ovis zur herstellung von antiviralen arzneimitteln und arzneimitteln gegen krebs |
DE10122233A1 (de) * | 2000-07-11 | 2002-01-24 | Bayer Ag | Verwendung von Stämmen des Parapoxvirus ovis gegen Organfibrosen |
IL153826A0 (en) | 2000-07-11 | 2003-07-31 | Bayer Ag | Use of strains of the parapox ovis virus against organ fibrosis |
DE10122451A1 (de) * | 2000-07-11 | 2002-04-04 | Bayer Ag | Verwendung von Stämmen des Parapoxvirus ovis zur Herstellung von antiviralen Arzneimitteln und Arzneimitteln gegen Krebs |
US7628980B2 (en) | 2000-11-23 | 2009-12-08 | Bavarian Nordic A/S | Modified vaccinia virus ankara for the vaccination of neonates |
US7445924B2 (en) | 2000-11-23 | 2008-11-04 | Bavarian Nordic A/S | Modified Vaccinia Ankara virus variant and cultivation method |
US7097842B2 (en) * | 2000-11-23 | 2006-08-29 | Bavarian Nordic A/S | Modified vaccinia virus ankara for the vaccination of neonates |
WO2004022729A1 (en) * | 2002-09-05 | 2004-03-18 | Bavarian Nordic A/S | Method for the cultivation of primary cells and for the amplification of viruses under serum free conditions |
EE05680B1 (et) | 2000-11-23 | 2013-10-15 | Bavarian Nordic A/S | Muundatud vaktsiiniaviirus, selle valmistamine ja kasutamine, seda sisaldav farmatseutiline kompositsioon ning vaktsiin |
UA82466C2 (uk) * | 2001-07-18 | 2008-04-25 | Бавариан Нордика А/С | Спосіб посилення ампліфікації хордопоксвірусу |
EP1456230A2 (en) | 2001-12-04 | 2004-09-15 | Bavarian Nordic A/S | Flavivirus ns1 subunit vaccine |
AU2002362072A1 (en) * | 2001-12-07 | 2003-06-23 | Board Of Regents The University Of Texas System | Use a parapox b2l protein to modify immune responses to administered antigens |
US6752995B2 (en) * | 2002-04-15 | 2004-06-22 | Board Of Regents, The University Of Texas System | Nucleic acid and polypeptide sequences useful as adjuvants |
US6723329B2 (en) * | 2001-12-07 | 2004-04-20 | Board Of Regents, The University Of Texas System | Use of parapox B2L protein to modify immune responses to administered antigens |
AU2003239805B2 (en) | 2002-04-19 | 2009-09-10 | Bavarian Nordic A/S | Modified vaccinia virus ankara for the vaccination of neonates |
DE102004003572A1 (de) | 2004-01-23 | 2005-08-18 | Bavarian Nordic A/S | Monoparamunitätsinducer basierend auf attenuierten Myxomaviren des Kaninchens |
PL1765370T3 (pl) * | 2004-07-13 | 2010-02-26 | Aicuris Gmbh & Co Kg | Parapoksywirusy w kombinacji z innymi czynnikami przeciwwirusowymi do leczenia HIV/AIDS |
DE102004046391A1 (de) * | 2004-09-24 | 2006-04-06 | Bioveta Ag | Neuer Impfstoff für veterinäre und humanmedizinische Prophylaxe und Therapie |
DE102005027956B4 (de) * | 2005-06-16 | 2009-10-22 | Mayr, Anton, Prof. Dr. Dr. h.c. mult. | Hochattenuierte Poxvirusstämme, Verfahren zu ihrer Herstellung und deren Verwendung als Paramunitätsinducer oder zur Herstellung von Vektor-Vakzinen |
US20140255447A1 (en) * | 2013-03-05 | 2014-09-11 | Biomune Company | Production of avian embryo cells |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3816139A1 (de) * | 1987-10-17 | 1989-04-27 | Bayer Ag | Verfahren zur herstellung von paramunitaetsinducern |
-
1994
- 1994-02-23 DE DE4405841A patent/DE4405841C1/de not_active Expired - Fee Related
- 1994-03-01 SI SI9430051T patent/SI0669133T1/xx unknown
- 1994-03-01 DE DE59402826T patent/DE59402826D1/de not_active Expired - Fee Related
- 1994-03-01 AT AT94103047T patent/ATE153242T1/de not_active IP Right Cessation
- 1994-03-01 ES ES94103047T patent/ES2102081T3/es not_active Expired - Lifetime
- 1994-03-01 DK DK94103047.0T patent/DK0669133T3/da active
- 1994-03-01 EP EP94103047A patent/EP0669133B1/de not_active Expired - Lifetime
-
1995
- 1995-01-17 AU AU14167/95A patent/AU690625B2/en not_active Ceased
- 1995-01-17 PL PL95316024A patent/PL182132B1/pl not_active IP Right Cessation
- 1995-01-17 NZ NZ278079A patent/NZ278079A/en unknown
- 1995-01-17 CA CA002182207A patent/CA2182207C/en not_active Expired - Fee Related
- 1995-01-17 JP JP7522088A patent/JP2873880B2/ja not_active Expired - Fee Related
- 1995-01-17 BR BR9506882A patent/BR9506882A/pt not_active Application Discontinuation
- 1995-01-17 WO PCT/EP1995/000160 patent/WO1995022978A1/en active IP Right Grant
- 1995-01-17 CN CN95191784A patent/CN1142187A/zh active Pending
- 1995-01-17 HU HU9601947A patent/HU220972B1/hu not_active IP Right Cessation
- 1995-01-17 KR KR1019960704653A patent/KR100196204B1/ko not_active IP Right Cessation
- 1995-01-17 US US08/693,052 patent/US6805870B1/en not_active Expired - Fee Related
-
1996
- 1996-08-20 NO NO19963462A patent/NO319250B1/no unknown
- 1996-08-22 FI FI963277A patent/FI116557B/fi not_active IP Right Cessation
-
1997
- 1997-05-22 GR GR960403502T patent/GR3023508T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
JPH09504803A (ja) | 1997-05-13 |
KR970701062A (ko) | 1997-03-17 |
SI0669133T1 (en) | 1997-10-31 |
PL316024A1 (en) | 1996-12-23 |
NO963462L (no) | 1996-08-20 |
EP0669133B1 (de) | 1997-05-21 |
DK0669133T3 (da) | 1997-07-14 |
AU1416795A (en) | 1995-09-11 |
CA2182207A1 (en) | 1995-08-31 |
AU690625B2 (en) | 1998-04-30 |
FI963277A0 (fi) | 1996-08-22 |
HU9601947D0 (en) | 1996-09-30 |
ATE153242T1 (de) | 1997-06-15 |
EP0669133A1 (de) | 1995-08-30 |
FI116557B (fi) | 2005-12-30 |
NZ278079A (en) | 1998-01-26 |
FI963277A (fi) | 1996-08-22 |
US6805870B1 (en) | 2004-10-19 |
KR100196204B1 (ko) | 1999-06-15 |
WO1995022978A1 (en) | 1995-08-31 |
PL182132B1 (pl) | 2001-11-30 |
CA2182207C (en) | 2000-02-29 |
JP2873880B2 (ja) | 1999-03-24 |
DE4405841C1 (de) | 1995-01-05 |
GR3023508T3 (en) | 1997-08-29 |
DE59402826D1 (de) | 1997-06-26 |
NO319250B1 (no) | 2005-07-04 |
HUT75545A (en) | 1997-05-28 |
HU220972B1 (hu) | 2002-07-29 |
CN1142187A (zh) | 1997-02-05 |
BR9506882A (pt) | 1997-08-19 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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