ES2091940T3 - Composicion basada en oligomero de hemoglobina y procedimiento para elaborar la misma. - Google Patents
Composicion basada en oligomero de hemoglobina y procedimiento para elaborar la misma.Info
- Publication number
- ES2091940T3 ES2091940T3 ES91914918T ES91914918T ES2091940T3 ES 2091940 T3 ES2091940 T3 ES 2091940T3 ES 91914918 T ES91914918 T ES 91914918T ES 91914918 T ES91914918 T ES 91914918T ES 2091940 T3 ES2091940 T3 ES 2091940T3
- Authority
- ES
- Spain
- Prior art keywords
- hemoglobin
- preparing
- procedure
- same
- based composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/795—Porphyrin- or corrin-ring-containing peptides
- C07K14/805—Haemoglobins; Myoglobins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Diabetes (AREA)
- Pharmacology & Pharmacy (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gastroenterology & Hepatology (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Genetics & Genomics (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Plural Heterocyclic Compounds (AREA)
- Polyethers (AREA)
- Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
UNA MEZCLA NO INMUNOGENICA DE MONOMEROS MODIFICADOS CON BASE DE HEMOGLOBINA Y OLIGOMEROS PRODUCIDOS POR LA POLIMERIZACION DE UNA SOLUCION CON BASE DE HEMOGLOBINA EN LA PRESENCIA DE UN ANILLO HETEROCICLICO DE TRES MIEMBROS, POR EJ, OXIRANO DE POLIETER. LA COMPOSICION DE HEMOGLOBINA MODIFICADA TIENE UN P SUB 50 AL MENOS EQUIVALENTE AL P SUB 50 DE LA HEMOGLOBINA DE CELULA SANGUINEA HUMANA.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US56931690A | 1990-08-17 | 1990-08-17 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2091940T3 true ES2091940T3 (es) | 1996-11-16 |
Family
ID=24274925
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES91914918T Expired - Lifetime ES2091940T3 (es) | 1990-08-17 | 1991-08-15 | Composicion basada en oligomero de hemoglobina y procedimiento para elaborar la misma. |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP0496866B1 (es) |
JP (1) | JP2689023B2 (es) |
AT (1) | ATE140389T1 (es) |
CA (1) | CA2067241A1 (es) |
DE (1) | DE69120925T2 (es) |
DK (1) | DK0496866T3 (es) |
ES (1) | ES2091940T3 (es) |
WO (1) | WO1992003153A1 (es) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5650388A (en) * | 1989-11-22 | 1997-07-22 | Enzon, Inc. | Fractionated polyalkylene oxide-conjugated hemoglobin solutions |
US5312808A (en) * | 1989-11-22 | 1994-05-17 | Enzon, Inc. | Fractionation of polyalkylene oxide-conjugated hemoglobin solutions |
DK145092D0 (es) * | 1992-12-03 | 1992-12-03 | Novo Nordisk As | |
US6242417B1 (en) * | 1994-03-08 | 2001-06-05 | Somatogen, Inc. | Stabilized compositions containing hemoglobin |
DE69912375T2 (de) * | 1998-04-24 | 2004-08-19 | Cv Therapeutics, Palo Alto | Adenosin a1 rezeptor antagonisten enthaltende zusammensetzung und verfahren zur wiederherstellung der diuretischen- und nierenfunktion |
US8084581B1 (en) * | 2011-04-29 | 2011-12-27 | Bing Lou Wong | Method for removing unmodified hemoglobin from cross-linked hemoglobin solutions including polymeric hemoglobin with a high temperature short time heat treatment apparatus |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4001200A (en) * | 1975-02-27 | 1977-01-04 | Alza Corporation | Novel polymerized, cross-linked, stromal-free hemoglobin |
US4001401A (en) * | 1975-02-02 | 1977-01-04 | Alza Corporation | Blood substitute and blood plasma expander comprising polyhemoglobin |
US4053590A (en) * | 1975-02-27 | 1977-10-11 | Alza Corporation | Compositions of matter comprising macromolecular hemoglobin |
JPS60258126A (ja) * | 1984-06-02 | 1985-12-20 | Teruo Tomota | 重合化ヘモグロビンの製造方法 |
US4598064A (en) * | 1984-06-27 | 1986-07-01 | University Of Iowa Research Foundation | Alpha-alpha cross-linked hemoglobins |
IL87708A (en) * | 1988-09-08 | 1994-04-12 | Technion Inst For Research And | Hemoglobin-based blood substitute possessing a colloid oncotic pressure substantially similar to human blood and method for the preparation thereof |
IL87707A (en) * | 1988-09-08 | 1994-06-24 | Technion Inst For Research And | Hemoglobin-based blood substitute substantially similar to human blood and method for preparation thereof |
-
1991
- 1991-08-15 JP JP3514532A patent/JP2689023B2/ja not_active Expired - Fee Related
- 1991-08-15 ES ES91914918T patent/ES2091940T3/es not_active Expired - Lifetime
- 1991-08-15 EP EP91914918A patent/EP0496866B1/en not_active Revoked
- 1991-08-15 AT AT91914918T patent/ATE140389T1/de not_active IP Right Cessation
- 1991-08-15 DE DE69120925T patent/DE69120925T2/de not_active Revoked
- 1991-08-15 WO PCT/US1991/005799 patent/WO1992003153A1/en not_active Application Discontinuation
- 1991-08-15 CA CA002067241A patent/CA2067241A1/en not_active Abandoned
- 1991-08-15 DK DK91914918.7T patent/DK0496866T3/da active
Also Published As
Publication number | Publication date |
---|---|
JP2689023B2 (ja) | 1997-12-10 |
ATE140389T1 (de) | 1996-08-15 |
WO1992003153A1 (en) | 1992-03-05 |
DE69120925T2 (de) | 1997-02-13 |
EP0496866B1 (en) | 1996-07-17 |
CA2067241A1 (en) | 1992-02-18 |
JPH05502240A (ja) | 1993-04-22 |
DE69120925D1 (de) | 1996-08-22 |
EP0496866A1 (en) | 1992-08-05 |
DK0496866T3 (da) | 1996-08-12 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
EP0502113A4 (en) | Chemically modified hemoglobin as an effective, stable, non-immunogenic red blood cell substitute | |
ES2147720T3 (es) | Factor de celulas madre. | |
UY23635A1 (es) | Procedimiento para la preparacion de conjugados del peg interferon | |
ES2092183T3 (es) | Procedimiento para la preparacion de poli(tereftalato de butileno) a partir de residuos de poli(tereftalato de etileno). | |
AR008680A1 (es) | Substitutos de plaquetas y metodos de conjugacion apropiados para su preparacion | |
BR9910251A (pt) | Estimulação hematopoiética | |
ATE193418T1 (de) | Dekontaminierung von plättchen mit 8- methoxypsoralen | |
IL93098A0 (en) | Alkylated polyethylenimine derivatives,process for their preparation and pharmaceutical preparations containing them | |
MX9201298A (es) | Nuevos conjugados de proteinas con poli etilen glicol, procedimiento para su preparacion y composicion farmaceutica que los contiene. | |
ATE358176T1 (de) | Menschliche dnase | |
IT1205978B (it) | Derivati di dicloroanilina,composizioni farmaceutiche che li contengono e procedimento per produrli | |
IT1142032B (it) | Preparato che favorisce la coagulazione del sangue a base di proteine umani, nonche' procedimento per la preparazione | |
ATE89167T1 (de) | Lyophilisation von erythrozyten und dafuer brauchbare mittel. | |
IL81147A0 (en) | Low viscosity high molecular weight,filter sterilizable hyaluronic acid and its preparation | |
NO922953L (no) | Rekombinant fremstilt blodfaktorer og fremgangsmaate for ekspresjon av blodfaktorene, samt vacciniavirusrekombinanter | |
ES8800605A1 (es) | Procedimiento para preparar una composicion coloeada de utilidad en cirugia ocular. | |
DE69028144D1 (de) | Verfahren zum Lagern von Erythrozyten | |
DK124787D0 (da) | Peptider indeholdende op til 8-aminosyregrupperinger og fysiologisk uskadelige salte deraf, deres fremstilling og anvendelse som laegemidler samt mellemprodukter ved fremstillingen | |
ES2091940T3 (es) | Composicion basada en oligomero de hemoglobina y procedimiento para elaborar la misma. | |
IT8920186A0 (it) | Catalizzatore di polimerizzazione, procedimento per la sua preparazione e suo impiego nella omo e copolimerizzazione di etilene. | |
ES2022501B3 (es) | Procedimiento para preparar un aducto de lactato calcico y glicerol, y su empleo. | |
ES2057528T3 (es) | Pdgf-a, pdgf-aa, pdgf-ab, procedimientos de preparacion y medicamentos que los contienen. | |
JPS5548205A (en) | Three-dimensional polycyanurate and its preparation | |
ES2033295T3 (es) | Un metodo para preparar un activador de plasminogeno. | |
FR2612185B1 (fr) | Derives oxo-isoindolinyliques optiquement actifs, leur preparation et leur utilisation comme medicaments |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
Ref document number: 496866 Country of ref document: ES |