ES2088470T3 - Ensayo de una etapa para recuento absoluto. - Google Patents
Ensayo de una etapa para recuento absoluto.Info
- Publication number
- ES2088470T3 ES2088470T3 ES91307209T ES91307209T ES2088470T3 ES 2088470 T3 ES2088470 T3 ES 2088470T3 ES 91307209 T ES91307209 T ES 91307209T ES 91307209 T ES91307209 T ES 91307209T ES 2088470 T3 ES2088470 T3 ES 2088470T3
- Authority
- ES
- Spain
- Prior art keywords
- stage
- trial
- absolute count
- reagent
- absolute
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000008280 blood Substances 0.000 abstract 2
- 210000004369 blood Anatomy 0.000 abstract 2
- 239000003153 chemical reaction reagent Substances 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 230000001413 cellular effect Effects 0.000 abstract 1
- 238000001514 detection method Methods 0.000 abstract 1
- 239000011859 microparticle Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56966—Animal cells
- G01N33/56977—HLA or MHC typing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56966—Animal cells
- G01N33/56972—White blood cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/80—Fluorescent dyes, e.g. rhodamine
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/805—Optical property
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
- Y10T436/101666—Particle count or volume standard or control [e.g., platelet count standards, etc.]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/11—Automated chemical analysis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Cell Biology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Food Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Zoology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
Abstract
ESTA INVENCION INCLUYE UN METODO DE UNA ETAPA PARA LA DETECCION Y ENUMERACION DE CONTAJES ABSOLUTOS DE UNA O MAS POBLACIONES CELULARES EN UNA MUESTRA DE SANGRE. EL METODO EMPLEA UN REACTIVO INCLUYENDO UNA MEZCLA DE UNO O MAS MARCADORES CELULARES, UNA MICROPARTICULA FLUORESCENTE Y UN FIJADOR. EL REACTIVO PUEDE ESTAR COMBINADO CON SANGRE COMPLETA NO LISADA Y ANALIZADO POR MEDIO DE CAUDAL CITOMETRICO.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US57056990A | 1990-08-07 | 1990-08-07 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2088470T3 true ES2088470T3 (es) | 1996-08-16 |
Family
ID=24280160
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES91307209T Expired - Lifetime ES2088470T3 (es) | 1990-08-07 | 1991-08-06 | Ensayo de una etapa para recuento absoluto. |
Country Status (19)
Country | Link |
---|---|
US (1) | US5627037A (es) |
EP (1) | EP0470810B1 (es) |
JP (1) | JPH07101218B2 (es) |
KR (1) | KR920004838A (es) |
AP (1) | AP266A (es) |
AT (1) | ATE136653T1 (es) |
AU (1) | AU642282B2 (es) |
BR (1) | BR9103400A (es) |
CA (1) | CA2048004A1 (es) |
DE (1) | DE69118617T2 (es) |
ES (1) | ES2088470T3 (es) |
FI (1) | FI913733A (es) |
IE (1) | IE76732B1 (es) |
MX (1) | MX9100553A (es) |
MY (1) | MY107807A (es) |
NO (1) | NO913063L (es) |
OA (1) | OA10036A (es) |
SG (1) | SG48820A1 (es) |
ZA (1) | ZA915958B (es) |
Families Citing this family (117)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2913219B2 (ja) * | 1991-03-06 | 1999-06-28 | 株式会社シマ研究所 | 尿沈渣検査成績管理方法 |
US5488469A (en) * | 1991-08-30 | 1996-01-30 | Omron Corporation | Cell analyzing apparatus |
EP0529666B1 (en) * | 1991-08-30 | 2000-04-12 | Omron Corporation | Cell analyzing apparatus |
US5451525A (en) * | 1992-02-14 | 1995-09-19 | Coulter Corporation | Method and materials for determining particle count in a flow cytometer |
FR2688309B1 (fr) * | 1992-03-06 | 1995-08-11 | Donzeau Jean Claude | Procede de controle preventif de l'immunite chez le sujet humain par l'etude de la population lymphocytaire. |
DE69326731T2 (de) * | 1992-09-04 | 2000-05-18 | Becton Dickinson Co | Kontroll-Teilchen für die Zellzählung und Instrumentenlinearität |
ES2051651B1 (es) * | 1992-12-10 | 1995-01-01 | Univ Salamanca | Procedimiento para la cuantificacion simultanea, en una sola medicion, de los principales tipos de linfocitos humanos y sus subpoblaciones. |
DE69428552T2 (de) * | 1993-01-26 | 2002-04-11 | Becton Dickinson Co | Verfahren zum Nachweis von seltenen Ereignissen |
US5585246A (en) * | 1993-02-17 | 1996-12-17 | Biometric Imaging, Inc. | Method for preparing a sample in a scan capillary for immunofluorescent interrogation |
US5879900A (en) * | 1994-12-15 | 1999-03-09 | Abbott Laboratories | Method for simultaneous analysis of cell viability, nucleated red blood cells and white blood cell differentials |
AUPN214095A0 (en) * | 1995-04-03 | 1995-04-27 | Australian Water Technologies Pty Ltd | Method for detecting microorganisms using flow cytometry |
AU752985B2 (en) | 1997-01-31 | 2002-10-03 | Xy, Llc. | Optical apparatus |
US6149867A (en) | 1997-12-31 | 2000-11-21 | Xy, Inc. | Sheath fluids and collection systems for sex-specific cytometer sorting of sperm |
US6211477B1 (en) | 1998-02-26 | 2001-04-03 | Becton Dickinson And Company | Electrostatic deceleration system for flow cytometer |
EP1125105A2 (en) | 1998-11-05 | 2001-08-22 | ChemoMetec A/S | A method for the assessment of particles and a system and a device for use in the method |
AU775260B2 (en) | 1999-03-31 | 2004-07-29 | Bayer Corporation | Single channel, single dilution detection method |
US6221668B1 (en) * | 1999-08-20 | 2001-04-24 | Streck Laboratories, Inc. | Hematology control and system for multi-parameter hematology measurements |
US7208265B1 (en) | 1999-11-24 | 2007-04-24 | Xy, Inc. | Method of cryopreserving selected sperm cells |
US6784981B1 (en) * | 2000-06-02 | 2004-08-31 | Idexx Laboratories, Inc. | Flow cytometry-based hematology system |
JPWO2002018947A1 (ja) * | 2000-08-30 | 2004-01-15 | 有限会社ゴールドラッシュ | 血液腫瘍の診断方法および診断薬 |
WO2002043574A2 (en) | 2000-11-29 | 2002-06-06 | Xy, Inc. | System to separate frozen-thawed spermatozoa into x-chromosome bearing and y-chromosome bearing populations |
US7713687B2 (en) | 2000-11-29 | 2010-05-11 | Xy, Inc. | System to separate frozen-thawed spermatozoa into x-chromosome bearing and y-chromosome bearing populations |
JP4612037B2 (ja) * | 2001-01-25 | 2011-01-12 | プレシジョン・システム・サイエンス株式会社 | 微小物識別装置およびその識別方法 |
WO2003006956A2 (en) | 2001-07-11 | 2003-01-23 | National Health Laboratory Service | Cell enumeration |
US7316772B2 (en) * | 2002-03-05 | 2008-01-08 | Enthone Inc. | Defect reduction in electrodeposited copper for semiconductor applications |
DK1363126T3 (da) * | 2002-05-14 | 2006-04-18 | Univ Salamanca | Flerdimensionel differentiel analyse af leukocyter |
USRE47770E1 (en) | 2002-07-18 | 2019-12-17 | Merus N.V. | Recombinant production of mixtures of antibodies |
DK2314629T4 (da) * | 2002-07-18 | 2023-02-06 | Merus Nv | Rekombinant produktion af blandinger af antistoffer |
US8486618B2 (en) | 2002-08-01 | 2013-07-16 | Xy, Llc | Heterogeneous inseminate system |
CA2532376C (en) * | 2002-08-01 | 2015-05-12 | Colorado State University Research Foundation | Low pressure sperm cell separation system |
MXPA05001654A (es) | 2002-08-15 | 2005-10-18 | Xy Inc | Citometro de flujo de alta resolucion. |
US7169548B2 (en) | 2002-09-13 | 2007-01-30 | Xy, Inc. | Sperm cell processing and preservation systems |
US7507548B2 (en) * | 2003-03-04 | 2009-03-24 | University Of Salamanca | Multidimensional detection of aberrant phenotypes in neoplastic cells to be used to monitor minimal disease levels using flow cytometry measurements |
CA3074799C (en) | 2003-03-28 | 2022-12-06 | Inguran, Llc | Apparatus, methods and processes for sorting particles and for providing sex-sorted animal sperm |
US20060263829A1 (en) * | 2003-05-15 | 2006-11-23 | Evans Kenneth M | Efficient haploid cell sorting flow cytometer systems |
US20100069614A1 (en) | 2008-06-27 | 2010-03-18 | Merus B.V. | Antibody producing non-human mammals |
AU2004242614B2 (en) | 2003-05-30 | 2011-09-22 | Merus N.V. | Fab library for the preparation of anti vegf and anti rabies virus fabs |
ES2646560T3 (es) | 2004-01-20 | 2017-12-14 | Merus N.V. | Mezclas de proteínas de unión |
JP4768706B2 (ja) * | 2004-03-03 | 2011-09-07 | ユニバーシダド デ サラマンカ | 流体血球計算測定を使用する最小疾患レベルを監視するのに使用される腫瘍性細胞中の異常表現型の多次元検出方法 |
US7892725B2 (en) | 2004-03-29 | 2011-02-22 | Inguran, Llc | Process for storing a sperm dispersion |
US7625712B2 (en) * | 2004-05-21 | 2009-12-01 | Beckman Coulter, Inc. | Method for a fully automated monoclonal antibody-based extended differential |
CA2574499C (en) | 2004-07-22 | 2016-11-29 | Monsanto Technology Llc | Process for enriching a population of sperm cells |
US20090258347A1 (en) * | 2004-12-14 | 2009-10-15 | University Of The Witwatersrand | Method for diagnosing and monitoring cellular reservoirs of disease |
EP1851545B1 (en) * | 2005-02-25 | 2014-12-31 | Dako Denmark A/S | Cell counting |
US7299135B2 (en) * | 2005-11-10 | 2007-11-20 | Idexx Laboratories, Inc. | Methods for identifying discrete populations (e.g., clusters) of data within a flow cytometer multi-dimensional data set |
US20090061478A1 (en) * | 2006-01-30 | 2009-03-05 | Lene Have Poulsen | High-Speed Quantification of Antigen Specific T-Cells in Whole Blood by Flow Cytometry |
US8241908B2 (en) * | 2006-05-16 | 2012-08-14 | Becton, Dickinson And Company | Extracellular matrix coated surface for culturing cells |
DE102007002614B4 (de) * | 2007-01-12 | 2009-04-02 | Jerichow, Ulrich, Dr. | Vorrichtung zur Überwachung, Steuerung und/oder Regelung einer Gaszusammensetzung |
WO2008116468A2 (en) * | 2007-03-26 | 2008-10-02 | Dako Denmark A/S | Mhc peptide complexes and uses thereof in infectious diseases |
EP3023436A1 (en) * | 2007-07-03 | 2016-05-25 | Dako Denmark A/S | Improved methods for generation, labeling and use of mhc multimers |
US7816135B2 (en) | 2007-07-05 | 2010-10-19 | Becton, Dickinson And Company | Method of analyzing lymphocytes |
US20090035802A1 (en) * | 2007-07-31 | 2009-02-05 | Digital Bio Technology, Co., Ltd. | Method for detection and enumeration of cell surface markers |
EP2197908A2 (en) | 2007-09-27 | 2010-06-23 | Dako Denmark A/S | Mhc multimers in tuberculosis diagnostics, vaccine and therapeutics |
US10968269B1 (en) | 2008-02-28 | 2021-04-06 | Agilent Technologies, Inc. | MHC multimers in borrelia diagnostics and disease |
BR122021026834B1 (pt) | 2008-04-25 | 2022-11-08 | Takeda Pharmaceutical Company Limited | Anticorpos isolados que se ligam a fcrn, composição farmacêutica que compreende os mesmos e métodos para detectar e para modular fcrn |
WO2010009735A2 (en) | 2008-07-23 | 2010-01-28 | Dako Denmark A/S | Combinatorial analysis and repair |
GB0817244D0 (en) * | 2008-09-20 | 2008-10-29 | Univ Cardiff | Use of a protein kinase inhibitor to detect immune cells, such as T cells |
US11992518B2 (en) | 2008-10-02 | 2024-05-28 | Agilent Technologies, Inc. | Molecular vaccines for infectious disease |
US10369204B2 (en) | 2008-10-02 | 2019-08-06 | Dako Denmark A/S | Molecular vaccines for infectious disease |
CA2740440A1 (en) | 2008-10-14 | 2010-04-22 | Dyax Corp. | Use of igf-ii/igf-iie binding proteins for the treatment and prevention of systemic sclerosis-associated pulmonary fibrosis |
US9506119B2 (en) | 2008-11-07 | 2016-11-29 | Adaptive Biotechnologies Corp. | Method of sequence determination using sequence tags |
US8628927B2 (en) | 2008-11-07 | 2014-01-14 | Sequenta, Inc. | Monitoring health and disease status using clonotype profiles |
US9365901B2 (en) | 2008-11-07 | 2016-06-14 | Adaptive Biotechnologies Corp. | Monitoring immunoglobulin heavy chain evolution in B-cell acute lymphoblastic leukemia |
US8748103B2 (en) | 2008-11-07 | 2014-06-10 | Sequenta, Inc. | Monitoring health and disease status using clonotype profiles |
US9528160B2 (en) | 2008-11-07 | 2016-12-27 | Adaptive Biotechnolgies Corp. | Rare clonotypes and uses thereof |
CN104195227B (zh) | 2008-11-07 | 2017-04-12 | 适应生物技术公司 | 通过序列分析监测状况的方法 |
EP2387627B1 (en) | 2009-01-15 | 2016-03-30 | Adaptive Biotechnologies Corporation | Adaptive immunity profiling and methods for generation of monoclonal antibodies |
RU2014144463A (ru) | 2009-06-25 | 2015-06-20 | Фред Хатчинсон Кансэр Рисёч Сентер | Способ измерения адаптивного иммунитета |
LT2521568T (lt) | 2010-01-06 | 2018-12-10 | Dyax Corp. | Plazmos kalikreiną surišantys baltymai |
CA2807440A1 (en) | 2010-08-04 | 2012-02-09 | Cizzle Biotechnology Limited | Methods and compounds for the diagnosis and treatment of cancer |
US20120065092A1 (en) | 2010-09-14 | 2012-03-15 | Wai Hobert | Fusion analyte cytometric bead assay, and systems and kits for performing the same |
EP3217178A3 (en) | 2010-11-12 | 2017-11-22 | incellDX, Inc. | Methods and systems for predicting whether a subject has a cervical intraepithelial neoplasia (cin) lesion from a suspension sample of cervical cells |
EP2643045A4 (en) | 2010-11-23 | 2016-01-13 | Presage Biosciences Inc | THERAPEUTIC PROCESSES AND COMPOSITIONS FOR SOLID FORM DELIVERY |
CN103429347B (zh) | 2010-12-09 | 2015-09-16 | 艾博特健康公司 | 使用抗吸附剂以方便样本混合及分析的装置和方法 |
WO2012079076A2 (en) * | 2010-12-10 | 2012-06-14 | The University Of North Carolina At Chapel Hill | Methods and systems for distributing a plurality of particles within a viscoelastic specimen |
JP6104233B2 (ja) * | 2011-05-04 | 2017-03-29 | アボット・ラボラトリーズAbbott Laboratories | 白血球分析システムおよび方法 |
AU2012262007B2 (en) | 2011-06-02 | 2017-06-22 | Takeda Pharmaceutical Company Limited | Fc receptor binding proteins |
EP2768982A4 (en) | 2011-10-21 | 2015-06-03 | Adaptive Biotechnologies Corp | QUANTIFICATION OF ADAPTIVE IMMUNOCELL GENOMES IN A COMPLEX MIX OF CELLS |
WO2013075031A1 (en) | 2011-11-16 | 2013-05-23 | Becton, Dickinson And Company | Methods and systems for detecting an analyte in a sample |
EP2788509B1 (en) | 2011-12-09 | 2018-07-11 | Adaptive Biotechnologies Corporation | Diagnosis of lymphoid malignancies and minimal residual disease detection |
US9499865B2 (en) | 2011-12-13 | 2016-11-22 | Adaptive Biotechnologies Corp. | Detection and measurement of tissue-infiltrating lymphocytes |
US20150056649A1 (en) * | 2012-01-13 | 2015-02-26 | Konica Minolta, Inc. | Method for quantifying cell of interest in blood, and method for evaluating system for quantifying said cell |
WO2013134162A2 (en) | 2012-03-05 | 2013-09-12 | Sequenta, Inc. | Determining paired immune receptor chains from frequency matched subunits |
WO2013138585A1 (en) * | 2012-03-16 | 2013-09-19 | The Broad Institute, Inc. | Multiplex methods to assay mixed cell populations simultaneously |
CN114163530A (zh) | 2012-04-20 | 2022-03-11 | 美勒斯公司 | 用于产生免疫球蛋白样分子的方法和手段 |
RU2631797C2 (ru) | 2012-05-08 | 2017-09-26 | Эдэптив Байотекнолоджиз Корпорейшн | Композиции и способы измерения и калибровки систематической ошибки амплификации в мультиплексных пцр-реакциях |
ES2660027T3 (es) | 2012-10-01 | 2018-03-20 | Adaptive Biotechnologies Corporation | Evaluación de la inmunocompetencia por la diversidad de los receptores de inmunidad adaptativa y caracterización de la clonalidad |
EP2926115B1 (en) | 2012-11-30 | 2021-05-26 | The University of North Carolina At Chapel Hill | Methods and systems for determining physical properties of a specimen in a portable point of care diagnostic device |
JP6296457B2 (ja) | 2013-01-11 | 2018-03-20 | ベクトン・ディキンソン・アンド・カンパニーBecton, Dickinson And Company | 低コストの臨床現場即時アッセイデバイス |
US9708657B2 (en) | 2013-07-01 | 2017-07-18 | Adaptive Biotechnologies Corp. | Method for generating clonotype profiles using sequence tags |
BR112016009958B1 (pt) | 2013-11-06 | 2021-08-03 | Becton, Dickinson And Company | Dispositivo microfluídico, método, sistema e kit |
CN105899936B (zh) | 2013-11-13 | 2019-12-24 | 贝克顿·迪金森公司 | 光学成像系统及使用其的方法 |
EP3114240B1 (en) | 2014-03-05 | 2019-07-24 | Adaptive Biotechnologies Corporation | Methods using randomer-containing synthetic molecules |
US10066265B2 (en) | 2014-04-01 | 2018-09-04 | Adaptive Biotechnologies Corp. | Determining antigen-specific t-cells |
EP3132059B1 (en) | 2014-04-17 | 2020-01-08 | Adaptive Biotechnologies Corporation | Quantification of adaptive immune cell genomes in a complex mixture of cells |
CA2935312C (en) | 2014-10-14 | 2022-11-22 | Becton, Dickinson And Company | Blood sample management using open cell foam |
PL3403579T3 (pl) | 2014-10-14 | 2020-10-19 | Becton, Dickinson And Company | Zarządzanie próbkami krwi z wykorzystaniem pianki o otwartych komórkach |
JP2016080563A (ja) * | 2014-10-20 | 2016-05-16 | 日本光電工業株式会社 | 分析システム、分析装置 |
EP3715455A1 (en) | 2014-10-29 | 2020-09-30 | Adaptive Biotechnologies Corp. | Highly-multiplexed simultaneous detection of nucleic acids encoding paired adaptive immune receptor heterodimers from many samples |
US10246701B2 (en) | 2014-11-14 | 2019-04-02 | Adaptive Biotechnologies Corp. | Multiplexed digital quantitation of rearranged lymphoid receptors in a complex mixture |
CA2968543C (en) | 2014-11-25 | 2024-04-02 | Adaptive Biotechnologies Corporation | Characterization of adaptive immune response to vaccination or infection using immune repertoire sequencing |
CN104458539A (zh) * | 2014-12-17 | 2015-03-25 | 重庆医科大学附属儿童医院 | 一种非诊断目的检测淋巴细胞增殖情况的方法及其试剂盒 |
AU2016222788B2 (en) | 2015-02-24 | 2022-03-31 | Adaptive Biotechnologies Corp. | Methods for diagnosing infectious disease and determining HLA status using immune repertoire sequencing |
WO2016145057A1 (en) | 2015-03-10 | 2016-09-15 | Becton, Dickinson And Company | Biological fluid micro-sample management device |
EP3268435B1 (en) | 2015-03-12 | 2022-07-13 | Becton, Dickinson and Company | Polymeric bodipy dyes and methods for using the same |
EP4353784A2 (en) | 2015-03-12 | 2024-04-17 | Becton Dickinson and Company | Ultraviolet absorbing polymeric dyes and methods for using the same |
WO2016161273A1 (en) | 2015-04-01 | 2016-10-06 | Adaptive Biotechnologies Corp. | Method of identifying human compatible t cell receptors specific for an antigenic target |
CA3109854C (en) | 2015-09-01 | 2023-07-25 | Becton, Dickinson And Company | Depth filtration device for separating specimen phases |
US10472521B2 (en) | 2015-12-16 | 2019-11-12 | Becton, Dickinson And Company | Photostable fluorescent polymeric tandem dyes including luminescent metal complexes |
EP3481901A4 (en) | 2016-07-07 | 2020-07-15 | Becton, Dickinson and Company | WATER SOLVATED FLUORESCENT CONJUGATED POLYMERS |
US10428325B1 (en) | 2016-09-21 | 2019-10-01 | Adaptive Biotechnologies Corporation | Identification of antigen-specific B cell receptors |
US11254980B1 (en) | 2017-11-29 | 2022-02-22 | Adaptive Biotechnologies Corporation | Methods of profiling targeted polynucleotides while mitigating sequencing depth requirements |
US10914913B2 (en) | 2018-03-30 | 2021-02-09 | Idexx Laboratories, Inc. | Flow cytometer, laser optics assembly thereof, and methods of assembling the same |
EP3875956A4 (en) | 2018-10-31 | 2022-07-27 | Takeda Pharmaceutical Company Limited | QUANTITATIVE FLOW CYTOMETRY |
WO2021231071A1 (en) * | 2020-05-13 | 2021-11-18 | Becton, Dickinson And Company | Blood based controls for complex panel |
CA3182847A1 (en) | 2020-06-17 | 2021-12-23 | Garland Christian Misener | Flow cytometer and laser optics assembly thereof |
EP4155349A1 (en) | 2021-09-24 | 2023-03-29 | Becton, Dickinson and Company | Water-soluble yellow green absorbing dyes |
Family Cites Families (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL135023C (es) * | 1958-03-13 | |||
US3433712A (en) * | 1965-01-28 | 1969-03-18 | Horace W Gerarde | Cholinesterase test |
US3464800A (en) * | 1966-10-27 | 1969-09-02 | Horace W Gerarde | Pipette assembly having precise quantity of dry stabilized reagent and method of preparing same |
US3463322A (en) * | 1967-07-28 | 1969-08-26 | Horace W Gerarde | Pressure filtration device |
US4110604A (en) * | 1976-11-04 | 1978-08-29 | Becton, Dickinson And Company | Particle density measuring system |
US4544546A (en) * | 1980-04-21 | 1985-10-01 | Abbott Laboratories | Fluorescent nucleic acid stains |
AR231590A1 (es) * | 1981-04-29 | 1984-12-28 | Ciba Geigy Ag | Dispositivo de analisis inmunologico y procedimiento para obtenerlo |
DE3238353A1 (de) * | 1982-10-15 | 1984-04-19 | Max Planck Gesellschaft zur Förderung der Wissenschaften e.V., 3400 Göttingen | Verfahren zur simultanen quantitativen bestimmung der blutzellen und reagenz hierfuer |
US4599307A (en) * | 1983-07-18 | 1986-07-08 | Becton, Dickinson And Company | Method for elimination of selected cell populations in analytic cytology |
US4677061A (en) * | 1984-10-19 | 1987-06-30 | Genetic Systems Corporation | T-cell lymphocyte subset monitoring of immunologic disease |
US4727020A (en) * | 1985-02-25 | 1988-02-23 | Becton, Dickinson And Company | Method for analysis of subpopulations of blood cells |
US4883867A (en) * | 1985-11-01 | 1989-11-28 | Becton, Dickinson And Company | Detection of reticulocytes, RNA or DNA |
DE3541033A1 (de) * | 1985-11-19 | 1987-05-21 | Boehringer Mannheim Gmbh | Verfahren zur quantifizierung von zellpopulationen bzw. subpopulationen sowie hierfuer geeignetes reagenz |
US4704891A (en) * | 1986-08-29 | 1987-11-10 | Becton, Dickinson And Company | Method and materials for calibrating flow cytometers and other analysis instruments |
JPS63214668A (ja) * | 1987-03-03 | 1988-09-07 | Hitachi Ltd | 細胞測定方法 |
US4876190A (en) * | 1987-10-21 | 1989-10-24 | Becton Dickinson & Company | Peridinin-chlorophyll complex as fluorescent label |
US4987086A (en) * | 1987-11-30 | 1991-01-22 | Becton, Dickinson And Company | Method for analysis of subpopulations of cells |
US5064616A (en) * | 1987-11-30 | 1991-11-12 | Becton Dickinson And Company | Kit for analysis of subsets of subpopulations of leukocytes |
US5057413A (en) * | 1988-06-13 | 1991-10-15 | Becton, Dickinson And Company | Method for discriminating between intact and damaged cells in a sample |
US5047321A (en) * | 1988-06-15 | 1991-09-10 | Becton Dickinson & Co. | Method for analysis of cellular components of a fluid |
FR2679660B1 (fr) * | 1991-07-22 | 1993-11-12 | Pasteur Diagnostics | Procede et dispositif magnetique d'analyse immunologique sur phase solide. |
-
1991
- 1991-07-24 IE IE262091A patent/IE76732B1/en not_active IP Right Cessation
- 1991-07-26 CA CA002048004A patent/CA2048004A1/en not_active Abandoned
- 1991-07-30 ZA ZA915958A patent/ZA915958B/xx unknown
- 1991-07-31 AU AU81528/91A patent/AU642282B2/en not_active Ceased
- 1991-08-05 MY MYPI91001417A patent/MY107807A/en unknown
- 1991-08-06 FI FI913733A patent/FI913733A/fi not_active Application Discontinuation
- 1991-08-06 NO NO91913063A patent/NO913063L/no unknown
- 1991-08-06 SG SG1996002038A patent/SG48820A1/en unknown
- 1991-08-06 ES ES91307209T patent/ES2088470T3/es not_active Expired - Lifetime
- 1991-08-06 DE DE69118617T patent/DE69118617T2/de not_active Expired - Lifetime
- 1991-08-06 EP EP91307209A patent/EP0470810B1/en not_active Expired - Lifetime
- 1991-08-06 AT AT91307209T patent/ATE136653T1/de not_active IP Right Cessation
- 1991-08-06 MX MX9100553A patent/MX9100553A/es unknown
- 1991-08-06 AP APAP/P/1991/000315A patent/AP266A/en active
- 1991-08-07 OA OA60059A patent/OA10036A/en unknown
- 1991-08-07 BR BR919103400A patent/BR9103400A/pt not_active Application Discontinuation
- 1991-08-07 JP JP3197907A patent/JPH07101218B2/ja not_active Expired - Lifetime
- 1991-08-07 KR KR1019910013636A patent/KR920004838A/ko not_active IP Right Cessation
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1994
- 1994-08-09 US US08/287,759 patent/US5627037A/en not_active Expired - Lifetime
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FI913733A (fi) | 1992-02-08 |
EP0470810A1 (en) | 1992-02-12 |
AU642282B2 (en) | 1993-10-14 |
ATE136653T1 (de) | 1996-04-15 |
AU8152891A (en) | 1992-02-13 |
DE69118617T2 (de) | 1996-10-31 |
BR9103400A (pt) | 1992-05-19 |
SG48820A1 (en) | 1998-05-18 |
OA10036A (en) | 1996-10-14 |
NO913063D0 (no) | 1991-08-06 |
JPH07101218B2 (ja) | 1995-11-01 |
EP0470810B1 (en) | 1996-04-10 |
KR920004838A (ko) | 1992-03-28 |
IE912620A1 (en) | 1992-02-12 |
DE69118617D1 (de) | 1996-05-15 |
IE76732B1 (en) | 1997-11-05 |
MY107807A (en) | 1996-06-29 |
US5627037A (en) | 1997-05-06 |
ZA915958B (en) | 1992-04-29 |
JPH04252957A (ja) | 1992-09-08 |
AP9100315A0 (en) | 1991-10-31 |
AP266A (en) | 1993-06-16 |
FI913733A0 (fi) | 1991-08-06 |
NO913063L (no) | 1992-02-10 |
CA2048004A1 (en) | 1992-02-08 |
MX9100553A (es) | 1992-04-01 |
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