DE60110407D1 - Reagenz zur bestimmung von blutplättchen-mikroteilchen - Google Patents

Reagenz zur bestimmung von blutplättchen-mikroteilchen

Info

Publication number
DE60110407D1
DE60110407D1 DE60110407T DE60110407T DE60110407D1 DE 60110407 D1 DE60110407 D1 DE 60110407D1 DE 60110407 T DE60110407 T DE 60110407T DE 60110407 T DE60110407 T DE 60110407T DE 60110407 D1 DE60110407 D1 DE 60110407D1
Authority
DE
Germany
Prior art keywords
reagent
mpp
micro particles
determining blood
blood plate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60110407T
Other languages
English (en)
Other versions
DE60110407T2 (de
Inventor
Michel Canton
Isabelle Botosezzy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biocytex SRL
Original Assignee
Biocytex SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biocytex SRL filed Critical Biocytex SRL
Application granted granted Critical
Publication of DE60110407D1 publication Critical patent/DE60110407D1/de
Publication of DE60110407T2 publication Critical patent/DE60110407T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/80—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood groups or blood types or red blood cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/01—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells
    • G01N2015/018—Platelets
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/1012—Calibrating particle analysers; References therefor
    • G01N2015/1014—Constitution of reference particles

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Zoology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DE60110407T 2000-05-16 2001-05-15 Reagenz zur bestimmung von blutplättchen-mikroteilchen Expired - Lifetime DE60110407T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR0006247A FR2809181B1 (fr) 2000-05-16 2000-05-16 Monoreactif pour le dosage des microparticules plaquettaires
FR0006247 2000-05-16
PCT/FR2001/001468 WO2001088539A1 (fr) 2000-05-16 2001-05-15 Monoreactif pour le dosage des microparticules plaquettaires

Publications (2)

Publication Number Publication Date
DE60110407D1 true DE60110407D1 (de) 2005-06-02
DE60110407T2 DE60110407T2 (de) 2006-03-09

Family

ID=8850288

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60110407T Expired - Lifetime DE60110407T2 (de) 2000-05-16 2001-05-15 Reagenz zur bestimmung von blutplättchen-mikroteilchen

Country Status (9)

Country Link
US (1) US20030175831A1 (de)
EP (1) EP1282817B1 (de)
JP (1) JP4831915B2 (de)
AT (1) ATE294392T1 (de)
CA (1) CA2410008A1 (de)
DE (1) DE60110407T2 (de)
ES (1) ES2238442T3 (de)
FR (1) FR2809181B1 (de)
WO (1) WO2001088539A1 (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107209101A (zh) * 2014-10-30 2017-09-26 鹿特丹伊拉斯谟大学医疗中心 用于诊断原发性免疫缺陷的试剂、方法和试剂盒

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050222030A1 (en) * 2001-02-21 2005-10-06 Anthony Allison Modified annexin proteins and methods for preventing thrombosis
US7645739B2 (en) * 2001-02-21 2010-01-12 Alavita Pharmaceuticals, Inc. Modified annexin compositions and methods of using same
US20090291086A1 (en) * 2001-02-21 2009-11-26 Alavita Pharmaceuticals, Inc. Compositions and Methods for Treating Cerebral Thrombosis and Global Cerebral Ischemia
US7635680B2 (en) * 2001-02-21 2009-12-22 Alavita Pharmaceuticals, Inc. Attenuation of reperfusion injury
US7635676B2 (en) * 2001-02-21 2009-12-22 Alavita Pharmaccuticals, Inc. Modified annexin proteins and methods for their use in organ transplantation
WO2005113006A2 (en) * 2004-05-13 2005-12-01 Boehringer Ingelheim International Gmbh Use of dipyridamole for treatment of resistance to platelet inhibitors
JP4029298B2 (ja) * 2004-07-26 2008-01-09 大塚製薬株式会社 粘着性マイクロベシクルの除去方法
ATE509270T1 (de) * 2005-02-21 2011-05-15 Univ Saga Aus blutplättchen gewonnene mikropartikel als neue diagnosemarker für eine herz-kreislauf- erkrankung
GB2428471A (en) * 2005-07-18 2007-01-31 Mathshop Ltd Flow cytometry
SE531041C2 (sv) * 2006-07-17 2008-11-25 Hemocue Ab Räkning av trombocyter
FR2917172B1 (fr) * 2007-06-07 2014-01-03 Inst Nat Sante Rech Med Methode de mesure de l'activite plasmine des microparticules presentes dans un echantillon de fluide biologique et utilisation
US8062222B2 (en) 2007-06-13 2011-11-22 Litron Laboratories, Ltd. Method for measuring in vivo hematotoxicity with an emphasis on radiation exposure assessment
JP2012168012A (ja) 2011-02-14 2012-09-06 Nippon Koden Corp 血管内皮障害を検査するための新規な検査方法および検査用キット
SG11201402649QA (en) * 2011-11-30 2014-06-27 Agency Science Tech & Res Gm1 ganglioside to annexin v microparticle polypeptide ratio for biological monitoring
CN108463722B (zh) * 2016-03-30 2021-09-21 西门子医疗保健诊断公司 用于处理血小板细胞数据的系统、方法和设备
JP7444386B2 (ja) * 2018-06-07 2024-03-06 株式会社Ｌｓｉメディエンス ヒト尿からのマイクロベシクルの分離方法及び分析方法
JP7376021B2 (ja) * 2018-06-07 2023-11-08 株式会社Ｌｓｉメディエンス ヒト血液からのマイクロベシクルの分離方法及び分析方法
CN111896736A (zh) * 2020-08-04 2020-11-06 江西赛基生物技术有限公司 活化血小板的检测方法和检测试剂盒

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4767206A (en) * 1984-12-24 1988-08-30 Flow Cytometry Standards Corporation Calibration method for flow cytometry using fluorescent microbeads and synthesis thereof
US5380663A (en) * 1984-12-24 1995-01-10 Caribbean Microparticles Corporation Automated system for performance analysis and fluorescence quantitation of samples
US5093234A (en) * 1984-12-24 1992-03-03 Caribbean Microparticles Corporation Method of aligning, compensating, and calibrating a flow cytometer for analysis of samples, and microbead standards kit therefor
CA2087086A1 (en) * 1992-01-22 1993-07-23 Leon Wmm Terstappen Multidimensional cell differential analysis
JP2680931B2 (ja) * 1993-11-12 1997-11-19 ベクトン・ディッキンソン・アンド・カンパニー 希少細胞の絶対数を数える方法
CA2185535C (en) * 1994-04-11 2000-10-24 Christiaan Peter Maria Reutelingsperger A method for detecting and/or optionally quantifying and/or separating apoptotic cells in or from a sample
US5552290A (en) * 1994-11-14 1996-09-03 University Of Massachusetts Medical Center Detection of procoagulant platelet-derived microparticles in whole blood
FR2795820A1 (fr) * 1999-07-01 2001-01-05 Biocytex Procede de quantification de microparticules endotheliales

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107209101A (zh) * 2014-10-30 2017-09-26 鹿特丹伊拉斯谟大学医疗中心 用于诊断原发性免疫缺陷的试剂、方法和试剂盒
CN107209101B (zh) * 2014-10-30 2019-10-25 鹿特丹伊拉斯谟大学医疗中心 用于诊断原发性免疫缺陷的试剂、方法和试剂盒

Also Published As

Publication number Publication date
CA2410008A1 (fr) 2001-11-22
ATE294392T1 (de) 2005-05-15
EP1282817A1 (de) 2003-02-12
FR2809181A1 (fr) 2001-11-23
WO2001088539A1 (fr) 2001-11-22
JP4831915B2 (ja) 2011-12-07
DE60110407T2 (de) 2006-03-09
EP1282817B1 (de) 2005-04-27
JP2003533698A (ja) 2003-11-11
FR2809181B1 (fr) 2002-10-25
ES2238442T3 (es) 2005-09-01
US20030175831A1 (en) 2003-09-18

Similar Documents

Publication Publication Date Title
DE60110407D1 (de) Reagenz zur bestimmung von blutplättchen-mikroteilchen
TWI256975B (en) Compositions containing a urea derivative dye for detecting an analyte and methods for using the same
AU1038402A (en) Assay for directly detecting a rs virus related biological cell in a body fluid sample
DE69429770D1 (de) Verfahren und analytisches system zur genauen schnellen und einfachen ausführung von fibrinogen-assays
AR053251A1 (es) Estrategias nuevas de etiquetado para la deteccion sensible de analitos
DE60038127D1 (de) Methoden und syteme zur überwachung intrazellulärer bindereaktionen
DE60030281D1 (de) Methoden zur verbesserung der sensitivität und spezifität von screeningverfahren für krebs und krebs-vorstufen
AU9648301A (en) Assay for rapid detection of human activated protein c and highly specific monoclonal antibody therefor
AU3538195A (en) Assays and devices for the detection of extrahepatic biliary atresia
ES2088470T3 (es) Ensayo de una etapa para recuento absoluto.
AU2003224447A1 (en) Device and method to simultaneously detect different antibodies and antigens in clinical alimentary and environmental samples
DE60013320D1 (de) Analytassay-vorrichtung mit vorabsorbieren-zone
DE60103428D1 (de) Identifizierung von zellen während kinetischer versuchsreihen
TR200103011T2 (tr) Bulaşıcı sünger tipi ansefalopatilerinin teşhisine yönelik metod.
EP0402846A3 (de) Fluoreszenzpolarisationsimmunoassay für Tetrahydrocannabinoide
ATE99697T1 (de) Ausscheidungsverfahren fuer die herstellung von thromboplastinreagenzien.
ATE384257T1 (de) Energiemessung von photonen von biologischen assays
DE69732034D1 (de) Assay-verfahren
CN101308132A (zh) 多联检测试剂盒
WO2004023146A3 (en) Methods for assaying protein-protein interactions
CA2358504A1 (en) Methods of determining an increased risk of a woman carrying a downs syndrome affected fetus by measuring an analyte in a biological sample
DK1192443T3 (da) Fremgangsmåde til kvantificering af endotel-mikrosfærer
HUP0400130A2 (en) Scintillation proximity assays for aminoglycoside binding molecules
DK1297342T3 (da) Metode til diagnostisk bestemmelse af Alzheimer's sygdom på basis af holo-transcobalamin II
ATE274702T1 (de) Verwendung derivatisierter reagenzien in chemilumineszenz- und elektrochemilumineszenz- nachweisverfahren

Legal Events

Date Code Title Description
8364 No opposition during term of opposition