ES2088427T3 - Ensayo simultaneo de dos analitos. - Google Patents

Ensayo simultaneo de dos analitos.

Info

Publication number
ES2088427T3
ES2088427T3 ES90905904T ES90905904T ES2088427T3 ES 2088427 T3 ES2088427 T3 ES 2088427T3 ES 90905904 T ES90905904 T ES 90905904T ES 90905904 T ES90905904 T ES 90905904T ES 2088427 T3 ES2088427 T3 ES 2088427T3
Authority
ES
Spain
Prior art keywords
antibody
component consisting
reaction component
concentration
assay
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90905904T
Other languages
English (en)
Inventor
Izak Bahar
Francis X Cole
L Edward Cannon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hygeia Sciences Inc
Original Assignee
Hygeia Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hygeia Sciences Inc filed Critical Hygeia Sciences Inc
Application granted granted Critical
Publication of ES2088427T3 publication Critical patent/ES2088427T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306—Solid-phase reaction mechanisms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • G01N33/743—Steroid hormones
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/81—Packaged device or kit
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/972—Modified antibody, e.g. hybrid, bifunctional
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/819—Multifunctional antigen or antibody

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Chemistry (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)

Abstract

UN ENSAYO ANALITICO DUAL SIMULTANEO PARA DETERMINAR EL PERIODO FERTIL DEL CICLO MENSTRUAL HUMANO. EL ENSAYO UTILIZA UN COMPONENTE DE REACCION CAPTURADO QUE CONSISTE EN P-3-G INMOVILIZADO EN UNA MEMBRANA MICROPOROSA, UN COMPONENTE DE REACCION BLOQUEANTE CONSISTENTE EN ANTICUERPOS ANTI E SUB 1-3-G, UN COMPONENTE DE REACCION ETIQUETADO, Y UN COMPONENTE DE REACCION AMBIFUNCIONAL CONSISTENTE EN UNA SUSTANCIA INMUNOCREADORA HIBRIDA CON UN LUGAR DE UNION DE ANTICUERPO ANTI P-3-G Y UNA PLURALIDAD DE LUGARES DE UNION DETERMINANTES E SUB 1-B-G. UNA MUESTRA ACUOSA CONTENIENDO P-3-G Y E SUB 1-3-G SE PONE EN CONTACTO CON LOS COMPONENTES Y SE CALIBRA EL ENSAYO PARA DAR UN RESULTADO DE ENSAYO POSITIVO SOLAMENTE CUANDO LA CONCENTRACION DE P-3-G EN LA MUESTRA ES MENOS DE UNA CONCENTRACION PREDETERMINADA Y LA CONCENTRACION DE E SUB 1-3-G EN LA MUESTRA ES MAS DE UNA CONCENTRACION PRESELECCIONADA POR LO QUE SE PRODUCE UNA CANTIDAD VISUALMENTE INESPERADA DE UN INMUNO COMPUESTO, QUE CONSISTE EN EL P-3-G INMOVILIZADO EN LA MEMBRANA MICROPOROSA Y EL ANTICUERPO ANTI E SUB 1-3-G ETIQUETADO EN ORO.
ES90905904T 1989-03-21 1990-03-07 Ensayo simultaneo de dos analitos. Expired - Lifetime ES2088427T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US32633789A 1989-03-21 1989-03-21

Publications (1)

Publication Number Publication Date
ES2088427T3 true ES2088427T3 (es) 1996-08-16

Family

ID=23271789

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90905904T Expired - Lifetime ES2088427T3 (es) 1989-03-21 1990-03-07 Ensayo simultaneo de dos analitos.

Country Status (9)

Country Link
US (1) US5242804A (es)
EP (1) EP0470966B1 (es)
JP (1) JP2955357B2 (es)
AT (1) ATE139032T1 (es)
CA (1) CA2049036A1 (es)
DE (1) DE69027320T2 (es)
DK (1) DK0470966T3 (es)
ES (1) ES2088427T3 (es)
WO (1) WO1990011521A1 (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9217864D0 (en) 1992-08-21 1992-10-07 Unilever Plc Monitoring method
US6121056A (en) * 1993-02-24 2000-09-19 Dade Behring Inc. Random detection of antigens with antibodies immobilized on soluble submicron particles
US5874216A (en) * 1996-02-23 1999-02-23 Ensys Environmental Products, Inc. Indirect label assay device for detecting small molecules and method of use thereof
JP3609240B2 (ja) * 1997-08-07 2005-01-12 日東電工株式会社 免疫学的検査法および免疫学的検査用キット
US20030186311A1 (en) * 1999-05-21 2003-10-02 Bioforce Nanosciences, Inc. Parallel analysis of molecular interactions
US6673562B2 (en) 2000-08-24 2004-01-06 Spectral Diagnostics, Inc. Differential immunoassay
US6998251B2 (en) * 2001-01-12 2006-02-14 Syngenta Participations Ag Nanoporous membrane reactor for miniaturized reactions and enhanced reaction kinetics
US8917272B2 (en) * 2009-09-30 2014-12-23 Mckesson Financial Holdings Methods, apparatuses, and computer program products for facilitating visualization and analysis of medical data
US8828329B2 (en) 2010-10-01 2014-09-09 Church & Dwight, Co., Inc. Electronic analyte assaying device
KR102459433B1 (ko) 2013-03-11 2022-10-25 메소 스케일 테크놀러지즈, 엘엘시 다중화 어세이를 수행하기 위한 올리고뉴클레오티드

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7807532A (nl) * 1978-07-13 1980-01-15 Akzo Nv Metaal-immunotest.
GB2029011B (en) * 1978-09-01 1983-02-02 Coulson W Use of a synthetic bifunctional ligand for the immunimetric determination of the concentration ratio of two solutes
IE54109B1 (en) * 1982-02-10 1989-06-21 Boots Celltech Diagnostics Assay
US4506009A (en) * 1982-03-30 1985-03-19 University Of California Heterogeneous immunoassay method
GB8607101D0 (en) * 1986-03-21 1986-04-30 Serono Diagnostics Ltd Immunoassay
US4853335A (en) * 1987-09-28 1989-08-01 Olsen Duane A Colloidal gold particle concentration immunoassay
US4952517A (en) * 1988-02-08 1990-08-28 Hygeia Sciences, Inc. Positive step immunoassay

Also Published As

Publication number Publication date
EP0470966A1 (en) 1992-02-19
DK0470966T3 (da) 1996-09-30
CA2049036A1 (en) 1990-09-22
DE69027320D1 (de) 1996-07-11
US5242804A (en) 1993-09-07
EP0470966B1 (en) 1996-06-05
EP0470966A4 (en) 1992-09-09
WO1990011521A1 (en) 1990-10-04
ATE139032T1 (de) 1996-06-15
JPH04506112A (ja) 1992-10-22
JP2955357B2 (ja) 1999-10-04
DE69027320T2 (de) 1996-11-07

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