ES2085855T3 - Nuevo microorganismo para la degradacion de moenomicinas, procedimiento para la degradacion, asi como la utilizacion de los productos de degradacion. - Google Patents

Nuevo microorganismo para la degradacion de moenomicinas, procedimiento para la degradacion, asi como la utilizacion de los productos de degradacion.

Info

Publication number
ES2085855T3
ES2085855T3 ES89115069T ES89115069T ES2085855T3 ES 2085855 T3 ES2085855 T3 ES 2085855T3 ES 89115069 T ES89115069 T ES 89115069T ES 89115069 T ES89115069 T ES 89115069T ES 2085855 T3 ES2085855 T3 ES 2085855T3
Authority
ES
Spain
Prior art keywords
degradation
moenomycines
procedure
well
new microorganism
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES89115069T
Other languages
English (en)
Inventor
Werner Dr Aretz
Dirk Dr Bottger
Gerhard Prof Dr Seibert
Alois Dr Tumulka
Peter Prof Dr Welzel
Kurt Hobert
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Application granted granted Critical
Publication of ES2085855T3 publication Critical patent/ES2085855T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/12—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by acids having the group -X-C(=X)-X-, or halides thereof, in which each X means nitrogen, oxygen, sulfur, selenium or tellurium, e.g. carbonic acid, carbamic acid
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/125—Saturated compounds having only one carboxyl group and containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/60—Unsaturated compounds containing ether groups, groups, groups, or groups the non-carboxylic part of the ether being unsaturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C07F9/091—Esters of phosphoric acids with hydroxyalkyl compounds with further substituents on alkyl
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
    • C07F9/6552—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/42—Hydroxy-carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/07—Bacillus

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

CON AYUDA DE NUEVOS BACILOS SE DESINTEGRAN ENZIMAS EXTRAIDAS DE ANTIBIOTICOS FOSFOGLICOLIPIDOS. EL PRODUCTO DE DESINTEGRACION DE MONOENZIMA MUESTRA ACTIVIDAD ANTIBIOTICA O SE EMPLEA PARA LA SINTESIS DE COMPONENTES UTILIZADOS PARA PRODUCIR INHIBIDORES DE TRANSGLICOSILASA.
ES89115069T 1988-08-20 1989-08-16 Nuevo microorganismo para la degradacion de moenomicinas, procedimiento para la degradacion, asi como la utilizacion de los productos de degradacion. Expired - Lifetime ES2085855T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3828337 1988-08-20

Publications (1)

Publication Number Publication Date
ES2085855T3 true ES2085855T3 (es) 1996-06-16

Family

ID=6361268

Family Applications (1)

Application Number Title Priority Date Filing Date
ES89115069T Expired - Lifetime ES2085855T3 (es) 1988-08-20 1989-08-16 Nuevo microorganismo para la degradacion de moenomicinas, procedimiento para la degradacion, asi como la utilizacion de los productos de degradacion.

Country Status (16)

Country Link
EP (1) EP0355679B1 (es)
JP (2) JP2863557B2 (es)
KR (1) KR900003361A (es)
AT (1) ATE134641T1 (es)
AU (2) AU619034B2 (es)
DE (1) DE58909610D1 (es)
DK (1) DK407789A (es)
ES (1) ES2085855T3 (es)
FI (1) FI893878A (es)
GR (1) GR3019332T3 (es)
IL (1) IL91354A0 (es)
NO (1) NO893327L (es)
NZ (1) NZ230352A (es)
PH (1) PH26511A (es)
PT (1) PT91469B (es)
ZA (1) ZA896310B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE134641T1 (de) * 1988-08-20 1996-03-15 Hoechst Ag Neuer mikroorganismus zum abbau von moenomycinen, verfahren zum abbau sowie die verwendung der abbauprodukte
DK0503419T3 (da) * 1991-03-08 1998-02-02 Hoechst Ag Fremgangsmåde til fremstilling af MA
US5316929A (en) * 1991-03-08 1994-05-31 Hoechst Aktiengesellschaft Process for the preparation of MA
EP0652205A3 (de) * 1993-11-04 1995-08-30 Hoechst Ag Moenomycin-Abbauprodukte mit hydroxylierter oder oxidierter Lipidseitenkette und Moenomycin-Analoga, ein Verfahren zur Herstellung und die Verwendung dieser Verbindungen.
DE19709897A1 (de) * 1997-03-11 1998-09-17 Hoechst Ag Wismutsalze von Antibiotika der Moenomycin-Gruppe, Verfahren zu ihrer Herstellung, ihre Verwendung und solche Salze enthaltende Arzneimittel
EP0872556A3 (de) * 1997-04-17 2000-06-14 Hoechst Aktiengesellschaft Verfahren zur Herstellung von Moenomycin A
EP1069130B1 (en) * 1999-07-15 2004-08-11 Hoechst Marion Roussel Moenomycin A Derivatives, their preparation, and use as antibacterial products

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL6601300A (es) * 1966-02-01 1967-08-02 Stamicarbon
EP0130327B1 (de) * 1983-05-21 1987-11-04 Hoechst Aktiengesellschaft Moenomycin A-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Antibiotika
ATE134641T1 (de) * 1988-08-20 1996-03-15 Hoechst Ag Neuer mikroorganismus zum abbau von moenomycinen, verfahren zum abbau sowie die verwendung der abbauprodukte

Also Published As

Publication number Publication date
FI893878A (fi) 1990-02-21
EP0355679A2 (de) 1990-02-28
JPH1171323A (ja) 1999-03-16
KR900003361A (ko) 1990-03-26
DK407789D0 (da) 1989-08-18
NZ230352A (en) 1991-07-26
IL91354A0 (en) 1990-03-19
PT91469B (pt) 1995-05-04
EP0355679A3 (de) 1991-07-24
PH26511A (en) 1992-08-07
JP2863557B2 (ja) 1999-03-03
NO893327D0 (no) 1989-08-18
DE58909610D1 (de) 1996-04-04
FI893878A0 (fi) 1989-08-17
JPH02150273A (ja) 1990-06-08
AU635452B2 (en) 1993-03-18
DK407789A (da) 1990-02-21
AU619034B2 (en) 1992-01-16
ATE134641T1 (de) 1996-03-15
NO893327L (no) 1990-02-21
ZA896310B (en) 1990-04-25
AU8835391A (en) 1992-02-06
GR3019332T3 (en) 1996-06-30
EP0355679B1 (de) 1996-02-28
AU3998589A (en) 1990-02-22
PT91469A (pt) 1990-03-08

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