ES2085833R - - Google Patents

Info

Publication number
ES2085833R
ES2085833R ES9401628A ES9401628A ES2085833R ES 2085833 R ES2085833 R ES 2085833R ES 9401628 A ES9401628 A ES 9401628A ES 9401628 A ES9401628 A ES 9401628A ES 2085833 R ES2085833 R ES 2085833R
Authority
ES
Spain
Prior art keywords
lower alkyl
derivatives
agents
carboximetilidencicloheptimidazole
chcoor3
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES9401628A
Other languages
English (en)
Other versions
ES2085833B1 (es
ES2085833A2 (es
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of ES2085833A2 publication Critical patent/ES2085833A2/es
Publication of ES2085833R publication Critical patent/ES2085833R/es
Application granted granted Critical
Publication of ES2085833B1 publication Critical patent/ES2085833B1/es
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

DERIVADOS DE CARBOXIMETILIDENCICLOHEPTIMIDAZOL Y METODO PARA PREPARARLOS. ESTOS DERIVADOS TIENEN LA FORMULA *FIG* (EN LA QUE R1 REPRESENTA UN ALQUILO INFERIOR; R2 REPRESENTA H O UN GRUPO ISOPROPILO; R3 REPRESENTA H, UN ALQUILO INFERIOR O -C(CH3)H-O-COOR4 (R4 ES UN ALQUILO INFERIOR O CICLOHEXILO); Y =CHCOOR3 ES UN GRUPO SUSTITUIDO EN LA POSICION 4 O LA 8; A REPRESENTA ESTOS COMPUESTOS SON UTILES COMO AGENTES ANTI-HIPERTENSIVOS Y ANTI-INSUFICIENCIA CARDIACA CONGESTIVA, Y COMO AGENTES REDUCTORES DE LA PRESION INTRAOCULAR.
ES09401628A 1993-07-30 1994-07-22 Derivados de carboximetilidencicloheptimidazol y metodo para prepararlos. Expired - Fee Related ES2085833B1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP19015393 1993-07-30

Publications (3)

Publication Number Publication Date
ES2085833A2 ES2085833A2 (es) 1996-06-01
ES2085833R true ES2085833R (es) 1996-06-16
ES2085833B1 ES2085833B1 (es) 1997-03-16

Family

ID=16253305

Family Applications (1)

Application Number Title Priority Date Filing Date
ES09401628A Expired - Fee Related ES2085833B1 (es) 1993-07-30 1994-07-22 Derivados de carboximetilidencicloheptimidazol y metodo para prepararlos.

Country Status (12)

Country Link
US (1) US5527815A (es)
KR (1) KR100303458B1 (es)
BE (1) BE1009376A4 (es)
CH (1) CH686726A5 (es)
DE (1) DE4427056B4 (es)
ES (1) ES2085833B1 (es)
FR (1) FR2708610B1 (es)
GB (1) GB2280438B (es)
IT (1) IT1276321B1 (es)
NL (1) NL9401247A (es)
SE (1) SE505562C2 (es)
ZA (1) ZA945190B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU767456B2 (en) 1998-07-06 2003-11-13 Bristol-Myers Squibb Company Biphenyl sulfonamides as dual angiotensin endothelin receptor antagonists
JP4018816B2 (ja) * 1998-09-08 2007-12-05 壽製薬株式会社 シクロヘプテノン誘導体及びその製造方法並びにそれを利用してシクロヘプトイミダゾール誘導体を製造する方法
US7105513B2 (en) * 2002-08-07 2006-09-12 Sanofi-Avertis Deutschland Gmbh Acylated, heteroaryl-condensed cycloalkenylamines and their use as pharmaceuticals

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4551452A (en) * 1983-12-21 1985-11-05 Pfizer Inc. Anti-inflammatory 2-methyl-2H-1,2-benzo-(or -thieno-)thiazine-3-carboxamide 1,1-dioxide derivatives, compositions, and method of use therefor
GB8502258D0 (en) * 1985-01-30 1985-02-27 Lilly Industries Ltd Organic compounds
US4870186A (en) * 1987-05-22 1989-09-26 E. I. Du Pont De Nemours And Company Tetrazole intermediates to antihypertensive compounds
US5064825A (en) * 1989-06-01 1991-11-12 Merck & Co., Inc. Angiotensin ii antagonists
IL95975A (en) * 1989-10-24 1997-06-10 Takeda Chemical Industries Ltd N-benzyl- 2-alkylbenzimidazole derivatives, their production and pharmaceutical compositions containing them
US5104891A (en) * 1989-12-11 1992-04-14 G. D. Searle & Co. Cycloheptimidazolone compounds as angiotensin ii antagonists for control of hypertension
US5294631A (en) * 1990-04-13 1994-03-15 Smithkline Beecham Corporation Substituted benzimidazoles useful as angiotension II receptor antagonists
US5196444A (en) * 1990-04-27 1993-03-23 Takeda Chemical Industries, Ltd. 1-(cyclohexyloxycarbonyloxy)ethyl 2-ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]benzimidazole-7-carboxylate and compositions and methods of pharmaceutical use thereof
JP2707390B2 (ja) * 1992-05-22 1998-01-28 壽製薬株式会社 シクロヘプトイミダゾ−ル誘導体及びその製造方法並びにこれを含有する薬剤

Also Published As

Publication number Publication date
SE9402596L (sv) 1995-01-31
ES2085833B1 (es) 1997-03-16
FR2708610A1 (fr) 1995-02-10
KR100303458B1 (ko) 2001-11-22
CH686726A5 (de) 1996-06-14
GB9415208D0 (en) 1994-09-21
DE4427056A1 (de) 1995-02-02
GB2280438B (en) 1997-07-30
SE505562C2 (sv) 1997-09-15
GB2280438A (en) 1995-02-01
ZA945190B (en) 1995-02-24
KR950003286A (ko) 1995-02-16
IT1276321B1 (it) 1997-10-28
ITMI941541A1 (it) 1996-01-21
NL9401247A (nl) 1995-02-16
ES2085833A2 (es) 1996-06-01
FR2708610B1 (fr) 1995-10-13
DE4427056B4 (de) 2006-08-03
SE9402596D0 (sv) 1994-07-29
US5527815A (en) 1996-06-18
BE1009376A4 (fr) 1997-03-04
ITMI941541A0 (it) 1994-07-21

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Legal Events

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EC2A Search report published

Date of ref document: 19940722

Kind code of ref document: R

Effective date: 19940722

FD1A Patent lapsed

Effective date: 20060724