ES2085001T3 - Combinacion de igf-i y igfbp para el anabolismo. - Google Patents

Combinacion de igf-i y igfbp para el anabolismo.

Info

Publication number
ES2085001T3
ES2085001T3 ES92903897T ES92903897T ES2085001T3 ES 2085001 T3 ES2085001 T3 ES 2085001T3 ES 92903897 T ES92903897 T ES 92903897T ES 92903897 T ES92903897 T ES 92903897T ES 2085001 T3 ES2085001 T3 ES 2085001T3
Authority
ES
Spain
Prior art keywords
igf
combination
mammal
igfbp
human
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92903897T
Other languages
English (en)
Inventor
Ross G Clark
Venkat R Mukku
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genentech Inc
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24624851&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2085001(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genentech Inc filed Critical Genentech Inc
Application granted granted Critical
Publication of ES2085001T3 publication Critical patent/ES2085001T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4743—Insulin-like growth factor binding protein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/30—Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Endocrinology (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

SE DESCRIBE UN METODO PARA PRODUCIR UN ESTADO ANABOLICO EN UN MAMIFERO COADMINISTRANDO POR INYECCION SUBCUTANEA DE UNA COMBINACION DE UNA CANTIDAD EFECTIVA DE IGF-I Y UNA PROTEINA DE ENLACE EN UNA RELACION MOLAR DEFINIDA EN LA AUSENCIA DE HORMONA DE CRECIMIENTO DE MANERA A PRODUCIR UNA MAYOR RESPUESTA ANABOLICA EN EL MAMIFERO QUE EL LLEVADO A CABO UTILIZANDO IGF-I EN UNA CANTIDAD IGUAL A LA USADA PARA IGF-I EN LA COMBINACION.PREFERENTEMENTE, LA IGF-I ES UNA SECUENCIA ORIGINARIA, IGF-I DE UN HUMANO MADURO. LA PROTEINA DE ENLACE ES IGFBP-3, Y EL MAMIFERO ES HUMANO O UN ANIMAL NO HUMANO DE IMPORTANCIA ECONOMICA TALES COMO UNA VACA O UN CERDO.
ES92903897T 1991-02-12 1992-01-13 Combinacion de igf-i y igfbp para el anabolismo. Expired - Lifetime ES2085001T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/654,436 US5187151A (en) 1991-02-12 1991-02-12 Use of binding protein with igf-i as an anabolic growth promoting agent

Publications (1)

Publication Number Publication Date
ES2085001T3 true ES2085001T3 (es) 1996-05-16

Family

ID=24624851

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92903897T Expired - Lifetime ES2085001T3 (es) 1991-02-12 1992-01-13 Combinacion de igf-i y igfbp para el anabolismo.

Country Status (10)

Country Link
US (1) US5187151A (es)
EP (1) EP0571417B1 (es)
JP (1) JPH06505235A (es)
AT (1) ATE135587T1 (es)
CA (1) CA2101340C (es)
DE (1) DE69209277T2 (es)
DK (1) DK0571417T3 (es)
ES (1) ES2085001T3 (es)
GR (1) GR3019851T3 (es)
WO (1) WO1992013556A1 (es)

Families Citing this family (55)

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US5374620A (en) * 1990-06-07 1994-12-20 Genentech, Inc. Growth-promoting composition and its use
US5681814A (en) * 1990-06-07 1997-10-28 Genentech, Inc. Formulated IGF-I Composition
US5126324A (en) * 1990-06-07 1992-06-30 Genentech, Inc. Method of enhancing growth in patients using combination therapy
US5643867A (en) * 1992-08-26 1997-07-01 Celtrix Pharmaceuticals, Inc. Method for treating catabolic conditions
CA2142455A1 (en) * 1992-08-26 1994-03-03 Andreas Sommer Method for systemic treatment of catabolic conditions and systemic tissue injury
US5407913A (en) * 1992-12-03 1995-04-18 Celtrix Pharmaceuticals, Inc. Method and composition for systemic treatment of tissue injury
US5273961A (en) * 1992-09-22 1993-12-28 Genentech, Inc. Method of prophylaxis of acute renal failure
WO1994009815A1 (en) * 1992-10-29 1994-05-11 Celtrix Pharmaceuticals, Inc. USES OF TGF-β RECEPTOR FRAGMENT AS A THERAPEUTIC AGENT
ATE143267T1 (de) * 1992-10-29 1996-10-15 Genentech Inc Methode zur behandlung oder verhütung von fettleibigkeit
US6124259A (en) * 1993-01-28 2000-09-26 Celtrix Pharmaceuticals, Inc. Method for treating ophthalmic disorders with IGFBP
AU6093794A (en) * 1993-01-29 1994-08-15 Synergen, Inc. Wound healing composition
US5459051A (en) * 1993-03-26 1995-10-17 Celtrix Pharmaceuticals, Inc. Methods and vectors for over-expression of ubiquitin fusion proteins in host cells
ES2241906T3 (es) * 1993-09-20 2005-11-01 Celtrix Pharmaceuticals, Inc. Tratamiento de trastornos inmunologicos y hematologicos con igfbp solo o asociado con igf.
JPH09509140A (ja) * 1993-11-15 1997-09-16 セルトリックス ファーマシューティカルズ，インコーポレイテッド 神経学的障害の治療方法
US6207640B1 (en) * 1994-04-07 2001-03-27 Genentech, Inc. Treatment of partial growth hormone insensitivity syndrome
US5824642A (en) * 1994-04-07 1998-10-20 Genentech, Inc. Treatment of partial growth hormone insensitivity syndrome
JPH10512235A (ja) * 1994-07-20 1998-11-24 セルトリックス ファーマシューティカルズ，インコーポレイテッド 骨形成の促進および骨再造形の調節のためのｉｇｆ／ｉｇｆｂｐ複合体
US5728676A (en) * 1994-09-08 1998-03-17 Ciba-Geigy Corporation Use of insulin-like growth factors I and II for inhibition of inflammatory response
AUPN271195A0 (en) * 1995-05-02 1995-05-25 Bunge Meat Industries Ltd. Method of selecting livestock
US5741776A (en) * 1995-05-22 1998-04-21 Genentech, Inc. Method of administration of IGF-I
US5565428A (en) * 1995-05-22 1996-10-15 Genentech, Inc. Method of administration of IGF-I
EP0766966A3 (en) * 1995-09-08 2001-02-28 Eli Lilly And Company Method of treating insulin resistance
US5948757A (en) * 1996-03-01 1999-09-07 Celtrix Pharmaceuticals, Inc. High dose IGF-1 therapy
US5747273A (en) * 1996-05-07 1998-05-05 Diagnostic Systems Laboratories, Inc. Immunoassay of total insulin-like growth factor binding protein-1
AUPN999096A0 (en) * 1996-05-22 1996-06-13 Northstar Biologicals Pty Ltd Peptides, antibodies, vaccines & uses thereof
US6156728A (en) 1996-11-01 2000-12-05 Genentech, Inc. Treatment of inner ear hair cells
US6593290B1 (en) 1996-11-01 2003-07-15 Genentech, Inc. Treatment of inner ear hair cells
US6066464A (en) * 1996-12-10 2000-05-23 Diagnostic Systems Laboratories, Inc. Immunoassay of IGF family of peptides, their binding proteins and related molecules in dried whole blood filter paper spots
US6025368A (en) * 1997-02-25 2000-02-15 Celtrix Pharmaceuticals, Inc. Method for treating the symptoms of chronic stress-related disorders using IGF
US6514937B1 (en) * 1997-02-25 2003-02-04 Celtrix Pharmaceuticals, Inc. Method of treating psychological and metabolic disorders using IGF or IGF/IGFBP-3
US6015786A (en) * 1997-02-25 2000-01-18 Celtrix Pharmaceuticals, Inc. Method for increasing sex steroid levels using IGF or IGF/IGFBP-3
US5824467A (en) * 1997-02-25 1998-10-20 Celtrix Pharmaceuticals Methods for predicting drug response
US6420518B1 (en) 1997-04-04 2002-07-16 Genetech, Inc. Insulin-like growth factor agonist molecules
US6121416A (en) 1997-04-04 2000-09-19 Genentech, Inc. Insulin-like growth factor agonist molecules
US6916790B2 (en) 1997-05-05 2005-07-12 Mayo Foundation For Medical Education And Research Treatment of osteoporosis
AU746423B2 (en) * 1997-05-05 2002-05-02 Mayo Foundation For Medical Education And Research Treatment of osteoporosis
US6548482B1 (en) 1997-05-05 2003-04-15 Mayo Foundation For Medical Education And Research Treatment of osteoporosis
TW586934B (en) * 1997-05-19 2004-05-11 Sumitomo Pharma Immunopotentiating composition
US6436897B2 (en) * 1998-06-01 2002-08-20 Celtrix Pharmaceuticals, Inc. Pharmaceutical formulations for IGF/IGFBP
US6417330B1 (en) 1998-06-01 2002-07-09 Celtrix Pharmaceuticals, Inc. Insulin-like growth factor binding protein variants
US7288516B1 (en) 1999-09-20 2007-10-30 Celtrix Pharmaceuticals, Inc. Null IGF for the treatment of cancer
JP2002526417A (ja) * 1998-10-02 2002-08-20 セルトリックス ファーマシューティカルズ，インコーポレイテッド 非甲状腺性疾患の治療方法
JP3971108B2 (ja) * 1999-01-06 2007-09-05 ジェネンテック・インコーポレーテッド インシュリン様成長因子（ｉｇｆ）ｉ突然変異体
DK1282437T3 (da) * 2000-05-16 2008-06-30 Genentech Inc Behandling af brusklidelser
AU9109001A (en) * 2000-09-19 2002-04-02 Bioexpertise Llc Method for use of IGF-binding protein for selective sensitization of target cells in vivo
AUPR030900A0 (en) * 2000-09-22 2000-10-12 Queensland University Of Technology Growth factor complex
MXPA03007042A (es) * 2001-02-09 2004-05-24 Genentech Inc Cristalizacion de igf-1.
US6914049B2 (en) * 2001-09-18 2005-07-05 Bioexpertise, Llc IGF-binding protein-derived peptide or small molecule
WO2003025121A2 (en) * 2001-09-18 2003-03-27 Bioexpertise, Llc Igf-binding protein-derived peptide or small molecule
US6887851B2 (en) * 2001-09-18 2005-05-03 Bioexpertise, Llc IGF-binding protein-derived peptide
ATE536186T1 (de) 2003-09-12 2011-12-15 Tercica Inc Verfahren zur behandlung von igf-1 (insulin-like growth factor 1)-mangel
JP2008511838A (ja) * 2004-08-30 2008-04-17 テルシカ・インク インシュリン様成長因子欠乏疾患の診断及び治療のための方法及び装置
JP5449134B2 (ja) * 2007-04-18 2014-03-19 プレーマクレ・アクチエボラーグ 未熟児合併症の治療及び／又は予防の方法と製品
JP7077229B2 (ja) * 2015-12-31 2022-05-30 シーメンス・ヘルスケア・ダイアグノスティックス・インコーポレーテッド 非組み換えヒトインスリン様成長因子結合タンパク質の濃縮物
US20190018025A1 (en) * 2015-12-31 2019-01-17 Siemens Healthcare Diagnostics Inc. Non-recombinant human insulin-like growth factor binding protein concentrate

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1163880B (it) * 1983-07-29 1987-04-08 Guido Vergari Fascetta di legatura
ATE81779T1 (de) * 1985-08-22 1992-11-15 Gropep Pty Ltd Peptidanalogedes insulinaehnlichen wachstumsfaktors-1 bei saeugetieren.
EP0308500B1 (en) * 1987-04-06 1993-06-16 Celtrix Pharmaceuticals, Inc. Human somatomedin carrier protein subunits and process for producing them
DK131988A (da) * 1988-03-11 1989-09-12 Erasmus University Igf-bindingsprotein, dna-struktur, der koder for igf-bindingsproteinet og vektor indeholdende denne dna-struktur
US5258287A (en) * 1988-03-22 1993-11-02 Genentech, Inc. DNA encoding and methods of production of insulin-like growth factor binding protein BP53
AU1955388A (en) * 1988-04-12 1989-11-03 Synergen, Inc. Method for potentiating and inhibiting insulin-like growth factor activity
DE3822646A1 (de) * 1988-07-05 1990-01-11 Steag Ag Verfahren zur gewinnung von sphaerischen feststoffteilchen insbesondere solchen zur verwendung als strahlperlen
ATE125268T1 (de) * 1988-07-15 1995-08-15 Cent Sydney Area Health Serv Säureempfindliche subeinheit eines insulinähnlichen wachstumfaktors-bindeprotein- komplexes.
GB8826451D0 (en) * 1988-11-11 1988-12-14 Sandoz Ltd Improvements in/relating to organic compounds
IL92816A0 (en) * 1988-12-22 1990-09-17 Biogrowth Inc Recombinant dna molecules,hosts,processes and human somatomedin carrier protein-like polypeptides

Also Published As

Publication number Publication date
DK0571417T3 (da) 1996-04-15
ATE135587T1 (de) 1996-04-15
CA2101340A1 (en) 1992-08-13
DE69209277T2 (de) 1996-10-31
EP0571417B1 (en) 1996-03-20
GR3019851T3 (en) 1996-08-31
WO1992013556A1 (en) 1992-08-20
EP0571417A1 (en) 1993-12-01
DE69209277D1 (de) 1996-04-25
CA2101340C (en) 2003-05-06
JPH06505235A (ja) 1994-06-16
US5187151A (en) 1993-02-16

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