ES2074208T3 - Cepa aesporogena de bacillus subtilis y su uso como huesped para la preparacion de productos heterologos. - Google Patents
Cepa aesporogena de bacillus subtilis y su uso como huesped para la preparacion de productos heterologos.Info
- Publication number
- ES2074208T3 ES2074208T3 ES91121211T ES91121211T ES2074208T3 ES 2074208 T3 ES2074208 T3 ES 2074208T3 ES 91121211 T ES91121211 T ES 91121211T ES 91121211 T ES91121211 T ES 91121211T ES 2074208 T3 ES2074208 T3 ES 2074208T3
- Authority
- ES
- Spain
- Prior art keywords
- heterological
- guest
- products
- preparation
- bacillus subtilis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 244000063299 Bacillus subtilis Species 0.000 title abstract 2
- 235000014469 Bacillus subtilis Nutrition 0.000 title abstract 2
- 230000015572 biosynthetic process Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/61—Growth hormone [GH], i.e. somatotropin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
- C12N15/75—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Bacillus
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/07—Bacillus
- C12R2001/125—Bacillus subtilis ; Hay bacillus; Grass bacillus
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Endocrinology (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Virology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
ESTA INVENCION SE REFIERE A UNA NUEVA CEPA ESPORAGENA DE BACILLUS SUBTILIS QUE SE HA DEPOSITADO EN EL CENTRAALBUREAU VOOR SCHIMMELCULTURES BAJO EL NOMBRE CBS 432.90. ESTA CEPA, QUE MUESTRA UNA FRECUENCIA DE REVERSION PARA LA FORMACION DE ESPORAS DE MENOS DE, APROXIMADAMENTE, 10 ELEVADO -8 Y BUENA ESTABILIDAD PLASMIDA, ES APTA COMO HUESPED EN UN SISTEMA DE VECTOR HUESPED PARA LA PREPARACION DE PRODUCTOS HETEROLOGOS DE INTERES.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT02247690A IT1244477B (it) | 1990-12-21 | 1990-12-21 | Ceppo asporigeno di bacillus subtilis e suo impiego come ospite per la preparazione di prodotti eterologhi |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2074208T3 true ES2074208T3 (es) | 1995-09-01 |
Family
ID=11196787
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES91121211T Expired - Lifetime ES2074208T3 (es) | 1990-12-21 | 1991-12-11 | Cepa aesporogena de bacillus subtilis y su uso como huesped para la preparacion de productos heterologos. |
Country Status (9)
Country | Link |
---|---|
US (1) | US6284490B1 (es) |
EP (1) | EP0492274B1 (es) |
JP (1) | JP3013008B2 (es) |
AT (1) | ATE114171T1 (es) |
DE (1) | DE69105188T2 (es) |
DK (1) | DK0492274T3 (es) |
ES (1) | ES2074208T3 (es) |
GR (1) | GR3014979T3 (es) |
IT (1) | IT1244477B (es) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2002097064A1 (fr) * | 2001-05-29 | 2002-12-05 | Kao Corporation | Micro-organismes hotes |
GB0116798D0 (en) | 2001-07-10 | 2001-08-29 | Secr Defence | Expression system |
CA2546083C (en) * | 2003-11-11 | 2014-01-21 | Higeta Shoyu Co., Ltd. | Novel brevibacillus choshinensis and method for producing protein using the microorganism as host |
JP5140307B2 (ja) * | 2007-04-10 | 2013-02-06 | 花王株式会社 | 組換え微生物 |
US8673290B2 (en) * | 2011-03-01 | 2014-03-18 | MYGALAXY Limited Company | Sporulation-deficient B. texasporus cells and methods for efficient and cost-effective inactivation and use thereof |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4302544A (en) * | 1979-10-15 | 1981-11-24 | University Of Rochester | Asporogenous mutant of B. subtilis for use as host component of HV1 system |
US4450235A (en) * | 1982-04-21 | 1984-05-22 | Cpc International Inc. | Asporogenic mutant of bacillus subtilis useful as a host in a host-vector system |
US4450236A (en) * | 1982-04-21 | 1984-05-22 | Cpc International Inc. | Asporogenic mutant of Bacillus subtilis useful as a host in a host-vector system |
US4465773A (en) * | 1982-04-21 | 1984-08-14 | Cpc International Inc. | Amylase-negative, asporogenous mutant of Bacillus subtilis useful as a host in a host-vector system |
IE58099B1 (en) * | 1984-06-06 | 1993-06-30 | Cpc International Inc | Amylase-negative, asporogenous mutant of bacillus subtilis useful as a host in a host-vector system |
JPH0669377B2 (ja) * | 1985-11-25 | 1994-09-07 | 工業技術院長 | Dna塩基配列およびベクタ− |
GB8727772D0 (en) * | 1987-11-27 | 1987-12-31 | Celltech Ltd | Host cells |
IT1223577B (it) * | 1987-12-22 | 1990-09-19 | Eniricerche Spa | Procedimento migliorato per la preparazione dell'ormone della crescita umano naturale in forma pura |
-
1990
- 1990-12-21 IT IT02247690A patent/IT1244477B/it active IP Right Grant
-
1991
- 1991-12-11 DE DE69105188T patent/DE69105188T2/de not_active Expired - Fee Related
- 1991-12-11 EP EP91121211A patent/EP0492274B1/en not_active Expired - Lifetime
- 1991-12-11 DK DK91121211.6T patent/DK0492274T3/da active
- 1991-12-11 AT AT91121211T patent/ATE114171T1/de not_active IP Right Cessation
- 1991-12-11 ES ES91121211T patent/ES2074208T3/es not_active Expired - Lifetime
- 1991-12-19 US US07/810,138 patent/US6284490B1/en not_active Expired - Fee Related
- 1991-12-20 JP JP3355272A patent/JP3013008B2/ja not_active Expired - Fee Related
-
1995
- 1995-02-08 GR GR940404127T patent/GR3014979T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
GR3014979T3 (en) | 1995-05-31 |
JPH04287686A (ja) | 1992-10-13 |
EP0492274A2 (en) | 1992-07-01 |
DK0492274T3 (da) | 1995-04-18 |
IT9022476A1 (it) | 1992-06-22 |
US6284490B1 (en) | 2001-09-04 |
EP0492274B1 (en) | 1994-11-17 |
DE69105188D1 (de) | 1994-12-22 |
IT1244477B (it) | 1994-07-15 |
EP0492274A3 (en) | 1993-09-22 |
JP3013008B2 (ja) | 2000-02-28 |
IT9022476A0 (it) | 1990-12-21 |
DE69105188T2 (de) | 1995-05-18 |
ATE114171T1 (de) | 1994-12-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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