ES2073505T3 - Medios de contraste. - Google Patents
Medios de contraste.Info
- Publication number
- ES2073505T3 ES2073505T3 ES90200580T ES90200580T ES2073505T3 ES 2073505 T3 ES2073505 T3 ES 2073505T3 ES 90200580 T ES90200580 T ES 90200580T ES 90200580 T ES90200580 T ES 90200580T ES 2073505 T3 ES2073505 T3 ES 2073505T3
- Authority
- ES
- Spain
- Prior art keywords
- medium
- concentration
- contrast media
- sodium
- agent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000002872 contrast media Substances 0.000 title abstract 3
- 229940039231 contrast media Drugs 0.000 title 1
- 229910001415 sodium ion Inorganic materials 0.000 abstract 3
- FKNQFGJONOIPTF-UHFFFAOYSA-N Sodium cation Chemical compound [Na+] FKNQFGJONOIPTF-UHFFFAOYSA-N 0.000 abstract 1
- 239000008135 aqueous vehicle Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 abstract 1
- 239000001509 sodium citrate Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/04—X-ray contrast preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/04—X-ray contrast preparations
- A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
- A61K49/0447—Physical forms of mixtures of two different X-ray contrast-enhancing agents, containing at least one X-ray contrast-enhancing agent which is a halogenated organic compound
Landscapes
- Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Non-Silver Salt Photosensitive Materials And Non-Silver Salt Photography (AREA)
- Electrochromic Elements, Electrophoresis, Or Variable Reflection Or Absorption Elements (AREA)
- Devices For Indicating Variable Information By Combining Individual Elements (AREA)
- Liquid Crystal (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Ultra Sonic Daignosis Equipment (AREA)
- Lubricants (AREA)
- Steroid Compounds (AREA)
- Magnetic Resonance Imaging Apparatus (AREA)
- Compositions Of Macromolecular Compounds (AREA)
Abstract
Un medio de contraste que comprende un agente de contraste de rayos X yodado no iónico en un medio vehículo acuoso fisiológicamente tolerable, caracterizado porque dicho medio tiene una concentración de iones sodio superior a 20 hasta 60 mM, con las condiciones de que, cuando dicho medio comprende citrato sódico, dicha concentración de iones sodio es al menos de 26 mM y que, cuando dicho agente es yoversol, dicha concentración de iones sodio está dentro del intervalo de 26 a 36 mM.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB898906130A GB8906130D0 (en) | 1989-03-17 | 1989-03-17 | Compositions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2073505T3 true ES2073505T3 (es) | 1995-08-16 |
Family
ID=10653498
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES90200580T Expired - Lifetime ES2073505T3 (es) | 1989-03-17 | 1990-03-09 | Medios de contraste. |
Country Status (32)
| Country | Link |
|---|---|
| US (1) | US5366722B1 (es) |
| EP (2) | EP0390242B1 (es) |
| JP (1) | JP2977045B2 (es) |
| KR (1) | KR920700701A (es) |
| CN (1) | CN1057703C (es) |
| AT (1) | ATE123954T1 (es) |
| AU (1) | AU638235B2 (es) |
| BG (1) | BG60951B1 (es) |
| CA (1) | CA2046886A1 (es) |
| CZ (1) | CZ281381B6 (es) |
| DD (1) | DD295992A5 (es) |
| DE (1) | DE69020208T2 (es) |
| DK (1) | DK0390242T3 (es) |
| EG (1) | EG19431A (es) |
| ES (1) | ES2073505T3 (es) |
| FI (1) | FI914337A0 (es) |
| GB (1) | GB8906130D0 (es) |
| GR (1) | GR3017133T3 (es) |
| HU (1) | HU206835B (es) |
| IE (1) | IE67885B1 (es) |
| IL (1) | IL93752A (es) |
| JO (1) | JO1619B1 (es) |
| NO (1) | NO302064B1 (es) |
| NZ (1) | NZ232954A (es) |
| OA (1) | OA09392A (es) |
| PT (1) | PT93471B (es) |
| RO (1) | RO112246B1 (es) |
| RU (1) | RU2088261C1 (es) |
| TR (1) | TR25111A (es) |
| WO (1) | WO1990011094A1 (es) |
| YU (1) | YU47911B (es) |
| ZA (1) | ZA902052B (es) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8919929D0 (en) * | 1989-09-04 | 1989-10-18 | Nycomed As | Compositions |
| US5869024A (en) * | 1989-11-29 | 1999-02-09 | Bracco International B.V. | Methods and compositions for using non-ionic contrast agents to reduce the risk of clot formation in diagnostic procedures |
| US5614638A (en) * | 1989-11-29 | 1997-03-25 | Bracco International B.V. | Nonionic radiographic contrast agents |
| GB9020091D0 (en) * | 1990-09-14 | 1990-10-24 | Nycomed As | Contrast media |
| RU2098131C1 (ru) | 1990-03-09 | 1997-12-10 | Нюкомед Имагинг А.С. | Контрастная среда и способ ее получения |
| US5527926A (en) * | 1990-11-26 | 1996-06-18 | Bracco International B.V. | Methods and compositions for using non-ionic contrast agents to reduce the risk of clot formation in diagnostic procedures |
| US5278311A (en) * | 1992-06-05 | 1994-01-11 | E. R. Squibb & Sons, Inc. | Nonionic radiographic contrast agents |
| IT1256248B (it) * | 1992-12-24 | 1995-11-29 | Bracco Spa | Formulazioni iniettabili acquose per radiodiagnostica comprendenti miscele di composti aromatici iodurati utili come agenti opacizzanti ai raggi x |
| GB9419206D0 (en) * | 1994-09-23 | 1994-11-09 | Nycomed Innovation Ab | Contrast media |
| GB9419203D0 (en) * | 1994-09-23 | 1994-11-09 | Nycomed Innovation Ab | Contrast media |
| DE59710863D1 (de) * | 1996-01-25 | 2003-11-20 | Schering Ag | Verbesserte kontrastmittenlösungen für die intravasale anwendung |
| EP0885616A1 (de) * | 1997-06-20 | 1998-12-23 | Schering Aktiengesellschaft | Verwendung von intravenösen Kontrastmitteln sowie Vorrichtungen für die Projektionsmammographie |
| MX2012005021A (es) * | 2009-10-29 | 2012-06-19 | Ge Healthcare As | Composicion diagnostica que comprende cationes de plasma teniendo un perfil de seguridad superior. |
| JP5947784B2 (ja) * | 2010-03-23 | 2016-07-06 | ジーイー・ヘルスケア・アクスイェ・セルスカプ | 安定化ｘ線診断用組成物の製法 |
| CN105579069A (zh) * | 2013-03-27 | 2016-05-11 | 通用电气医疗集团股份有限公司 | 用于制备诊断组合物的方法和试剂 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2909439A1 (de) * | 1979-03-08 | 1980-09-18 | Schering Ag | Neue nichtionische roentgenkontrastmittel |
| DE2928417A1 (de) * | 1979-07-12 | 1981-01-29 | Schering Ag | Trijodierte basen |
| DE3038853A1 (de) * | 1980-10-10 | 1982-05-27 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | Neue n-hydroxy-alkylierte dicarbonsaeure-bis-(3,5-dicarbamoyl-2,4,6-trijodanilide), deren herstellung und diese enthaltende roentgenkonstrastmittel (ii) |
| US4957939A (en) * | 1981-07-24 | 1990-09-18 | Schering Aktiengesellschaft | Sterile pharmaceutical compositions of gadolinium chelates useful enhancing NMR imaging |
| ATE72398T1 (de) * | 1984-06-22 | 1992-02-15 | Richard L Veech | Polyanionische materialien enthaltende elektrolytloesungen. |
| US4663289A (en) * | 1984-06-22 | 1987-05-05 | Veech Richard L | Electrolyte solutions and in vitro use thereof |
| US4863714A (en) * | 1987-02-05 | 1989-09-05 | Cook Imaging Corporation | Sterilization of compositions of limited stability |
| US5011925A (en) * | 1989-03-09 | 1991-04-30 | Mallinckrodt, Inc. | Morpholinoamido EDTA derivatives |
-
1989
- 1989-03-17 GB GB898906130A patent/GB8906130D0/en active Pending
-
1990
- 1990-03-09 RO RO148301A patent/RO112246B1/ro unknown
- 1990-03-09 RU SU5010018/14A patent/RU2088261C1/ru active
- 1990-03-09 AU AU51854/90A patent/AU638235B2/en not_active Ceased
- 1990-03-09 AT AT90200580T patent/ATE123954T1/de not_active IP Right Cessation
- 1990-03-09 CA CA002046886A patent/CA2046886A1/en not_active Withdrawn
- 1990-03-09 WO PCT/EP1990/000393 patent/WO1990011094A1/en not_active Application Discontinuation
- 1990-03-09 EP EP90200580A patent/EP0390242B1/en not_active Expired - Lifetime
- 1990-03-09 KR KR1019910701153A patent/KR920700701A/ko not_active Application Discontinuation
- 1990-03-09 DK DK90200580.0T patent/DK0390242T3/da active
- 1990-03-09 HU HU902356A patent/HU206835B/hu not_active IP Right Cessation
- 1990-03-09 EP EP90904340A patent/EP0463013A1/en active Pending
- 1990-03-09 JP JP2504207A patent/JP2977045B2/ja not_active Expired - Lifetime
- 1990-03-09 ES ES90200580T patent/ES2073505T3/es not_active Expired - Lifetime
- 1990-03-09 DE DE69020208T patent/DE69020208T2/de not_active Expired - Lifetime
- 1990-03-14 IL IL9375290A patent/IL93752A/en not_active IP Right Cessation
- 1990-03-14 YU YU50390A patent/YU47911B/sh unknown
- 1990-03-15 DD DD90338762A patent/DD295992A5/de not_active IP Right Cessation
- 1990-03-15 CZ CS901257A patent/CZ281381B6/cs unknown
- 1990-03-16 TR TR90/0280A patent/TR25111A/xx unknown
- 1990-03-16 PT PT93471A patent/PT93471B/pt not_active IP Right Cessation
- 1990-03-16 ZA ZA902052A patent/ZA902052B/xx unknown
- 1990-03-16 IE IE97090A patent/IE67885B1/en not_active IP Right Cessation
- 1990-03-16 NZ NZ232954A patent/NZ232954A/en unknown
- 1990-03-17 CN CN90101396A patent/CN1057703C/zh not_active Expired - Lifetime
- 1990-03-17 JO JO19901619A patent/JO1619B1/en active
- 1990-03-18 EG EG17490A patent/EG19431A/xx active
-
1991
- 1991-08-19 OA OA60064A patent/OA09392A/xx unknown
- 1991-09-16 NO NO913641A patent/NO302064B1/no not_active IP Right Cessation
- 1991-09-16 FI FI914337A patent/FI914337A0/fi not_active Application Discontinuation
- 1991-10-16 BG BG95330A patent/BG60951B1/bg unknown
-
1993
- 1993-11-24 US US08156998 patent/US5366722B1/en not_active Expired - Lifetime
-
1995
- 1995-08-16 GR GR950402252T patent/GR3017133T3/el unknown
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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