ES2072395T3 - Uso de interleuquina-4 para aumentar el numero de neutrofilos y para tratar la leucemia mieloide y monocitoide. - Google Patents

Uso de interleuquina-4 para aumentar el numero de neutrofilos y para tratar la leucemia mieloide y monocitoide.

Info

Publication number
ES2072395T3
ES2072395T3 ES90308198T ES90308198T ES2072395T3 ES 2072395 T3 ES2072395 T3 ES 2072395T3 ES 90308198 T ES90308198 T ES 90308198T ES 90308198 T ES90308198 T ES 90308198T ES 2072395 T3 ES2072395 T3 ES 2072395T3
Authority
ES
Spain
Prior art keywords
interleukin
monocitoid
neutrophils
leukemia
increase
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90308198T
Other languages
English (en)
Inventor
Eric Bonnem
Lee Sullivan
Michael Grace
Loretta Bober
John Chu-Tay Tang
David Naveh
T L Nagabhushan
Jay Raman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sharp and Dohme Corp
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Application granted granted Critical
Publication of ES2072395T3 publication Critical patent/ES2072395T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/5406—IL-4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Toxicology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Manufacture Of Alloys Or Alloy Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Manufacture Of Macromolecular Shaped Articles (AREA)

Abstract

Uso de IL-4 en la fabricación de una composición farmacéutica para aumentar el número de neutrófilos en un mamífero.
ES90308198T 1989-07-28 1990-07-26 Uso de interleuquina-4 para aumentar el numero de neutrofilos y para tratar la leucemia mieloide y monocitoide. Expired - Lifetime ES2072395T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US38693789A 1989-07-28 1989-07-28

Publications (1)

Publication Number Publication Date
ES2072395T3 true ES2072395T3 (es) 1995-07-16

Family

ID=23527716

Family Applications (2)

Application Number Title Priority Date Filing Date
ES90308198T Expired - Lifetime ES2072395T3 (es) 1989-07-28 1990-07-26 Uso de interleuquina-4 para aumentar el numero de neutrofilos y para tratar la leucemia mieloide y monocitoide.
ES94105833T Expired - Lifetime ES2089875T3 (es) 1989-07-28 1990-07-26 Metodo para purificar interleuquina-4.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES94105833T Expired - Lifetime ES2089875T3 (es) 1989-07-28 1990-07-26 Metodo para purificar interleuquina-4.

Country Status (20)

Country Link
EP (3) EP0484380A1 (es)
JP (2) JP2580391B2 (es)
KR (1) KR100191223B1 (es)
AT (2) ATE119395T1 (es)
AU (2) AU645514B2 (es)
CA (1) CA2064753A1 (es)
DE (2) DE69017547T2 (es)
DK (2) DK0618220T3 (es)
ES (2) ES2072395T3 (es)
FI (2) FI102039B (es)
GR (1) GR3019707T3 (es)
HK (1) HK185196A (es)
HU (1) HU215257B (es)
IL (2) IL95201A0 (es)
NO (1) NO304555B1 (es)
OA (1) OA09649A (es)
RU (1) RU2082756C1 (es)
SG (1) SG44544A1 (es)
WO (1) WO1991001744A2 (es)
ZA (1) ZA905896B (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5077388A (en) * 1990-05-31 1991-12-31 Schering Corporation Purification of human interleukin-4 from a secreted escherichia coli mutant
US5723119A (en) * 1989-07-28 1998-03-03 Schering Corporation Method for enhancing wound healing/repair with IL-4
US5827670A (en) * 1990-08-02 1998-10-27 Fred Hutchinson Cancer Research Center Methods of isolating and detecting bone marrow stromal cells with VCAM-1-specific antibodies
US7449186B1 (en) 1990-08-02 2008-11-11 Fred Hutchinson Cancer Research Center Methods of blocking the interaction between stromal cells and hemopoietic cells with anti-VCAM-1 antibodies
AU660942B2 (en) * 1990-09-13 1995-07-13 Commonwealth Scientific And Industrial Research Organisation Ovine cytokine genes
DE69209051T2 (de) * 1991-01-10 1996-08-08 Schering Corp Verwendung von il-4 zur verstärkung von wundheilung und besserung und zur heilung von infizierten wunden und wunden bei diabetischen säugetieren
JPH07165602A (ja) * 1993-12-16 1995-06-27 Kirin Brewery Co Ltd 放射線障害防護剤
US5716612A (en) * 1994-09-07 1998-02-10 Schering Corporation Use of IL-4 for potentiation of chemotherapeutic agents
US6132737A (en) * 1997-09-29 2000-10-17 Revlon Consumer Products Corporation Method for reducing sunburn cell formation with cosmetic compositions containing ascorbic acid
DK2055313T3 (en) * 1998-11-09 2015-07-27 Biogen Inc Treatment of Hematologic Malignancies Related to Circulating Tumor Cells Using Chimeric Anti-CD20 Antibody
KR101742332B1 (ko) * 2009-04-20 2017-05-31 갈렌바이오 인코포레이티드 생체분자로 세포를 형질감염시키기 위한 조성물
JP5784416B2 (ja) * 2011-08-26 2015-09-24 出光興産株式会社 菌類の回収方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4723000A (en) * 1983-07-05 1988-02-02 Biospectrum, Inc. Human interferon gamma and interleukin-2
SE8701004D0 (sv) * 1987-03-11 1987-03-11 Astra Ab Method for therapy of leukemias and certain other malignancies
US5077388A (en) * 1990-05-31 1991-12-31 Schering Corporation Purification of human interleukin-4 from a secreted escherichia coli mutant
HUT63062A (en) * 1990-03-21 1993-07-28 Schering Corp Process for producing pharmaceutical compositions increasing the immune response and comprising il-4

Also Published As

Publication number Publication date
HU9200254D0 (en) 1992-04-28
RU2082756C1 (ru) 1997-06-27
AU6055890A (en) 1991-03-11
FI102039B1 (fi) 1998-10-15
ZA905896B (en) 1991-04-24
HK185196A (en) 1996-10-11
JPH0940575A (ja) 1997-02-10
AU645514B2 (en) 1994-01-20
ATE135366T1 (de) 1996-03-15
KR100191223B1 (ko) 1999-06-15
NO920351D0 (no) 1992-01-27
WO1991001744A3 (en) 1991-04-04
DK0410750T3 (da) 1995-07-10
SG44544A1 (en) 1997-12-19
WO1991001744A2 (en) 1991-02-21
IL121897A0 (en) 1998-03-10
DE69025961D1 (de) 1996-04-18
DK0618220T3 (da) 1996-07-22
NO304555B1 (no) 1999-01-11
FI102039B (fi) 1998-10-15
CA2064753A1 (en) 1991-01-29
GR3019707T3 (en) 1996-07-31
HUT60146A (en) 1992-08-28
DE69025961T2 (de) 1996-10-31
KR920700670A (ko) 1992-08-10
IL95201A0 (en) 1991-06-10
OA09649A (en) 1993-05-15
EP0410750B1 (en) 1995-03-08
FI920367A0 (fi) 1992-01-28
EP0410750A2 (en) 1991-01-30
DE69017547T2 (de) 1995-11-02
NO920351L (no) 1992-03-27
EP0410750A3 (en) 1991-06-19
AU661221B2 (en) 1995-07-13
JP2580391B2 (ja) 1997-02-12
FI981585A0 (fi) 1990-07-26
JPH04506299A (ja) 1992-11-05
EP0484380A1 (en) 1992-05-13
EP0618220A1 (en) 1994-10-05
DE69017547D1 (de) 1995-04-13
ES2089875T3 (es) 1996-10-01
FI981585A (fi) 1998-07-10
HU215257B (hu) 1998-11-30
AU5476194A (en) 1994-06-02
ATE119395T1 (de) 1995-03-15
EP0618220B1 (en) 1996-03-13

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