ES2067725T3 - Alergenos modificados quimicamente y procedimiento para su preparacion. - Google Patents
Alergenos modificados quimicamente y procedimiento para su preparacion.Info
- Publication number
- ES2067725T3 ES2067725T3 ES90830412T ES90830412T ES2067725T3 ES 2067725 T3 ES2067725 T3 ES 2067725T3 ES 90830412 T ES90830412 T ES 90830412T ES 90830412 T ES90830412 T ES 90830412T ES 2067725 T3 ES2067725 T3 ES 2067725T3
- Authority
- ES
- Spain
- Prior art keywords
- chemically modified
- groups
- allergic
- procedure
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000000034 method Methods 0.000 title abstract 2
- 239000013566 allergen Substances 0.000 title 1
- 230000000172 allergic effect Effects 0.000 abstract 3
- -1 AMINO Chemical class 0.000 abstract 2
- 208000010668 atopic eczema Diseases 0.000 abstract 2
- 238000011282 treatment Methods 0.000 abstract 2
- ZRALSGWEFCBTJO-UHFFFAOYSA-N Guanidine Chemical group NC(N)=N ZRALSGWEFCBTJO-UHFFFAOYSA-N 0.000 abstract 1
- 206010020751 Hypersensitivity Diseases 0.000 abstract 1
- 208000026935 allergic disease Diseases 0.000 abstract 1
- 230000007815 allergy Effects 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 230000001939 inductive effect Effects 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/35—Allergens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/35—Allergens
- A61K39/36—Allergens from pollen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/806—Antigenic peptides or proteins
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Pulmonology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Abstract
INDUCTORES DE ALERGIA QUIMICAMENTE MODIFICADOS, CUYA ACTIVIDAD ALERGICA SE REDUCE CON RESPECTO A LA DE LOS MATERIALES ALERGICOS NATIVOS CORRESPONDIENTES, LOS CUALES SON CAPACES DE INDUCIR ANTICUERPOS ESPECIFICOS DIRIGIDOS A DICHO MATERIAL ALERGICO NATIVO, EN DONDE UNA PARTE DE LOS GRUPOS AMINO PRIMARIOS DE LA MOLECULA DE PROTEINA DEL I. ALERGICO NATIVO SE MODIFICAN QUIMICAMENTE DE MODO QUE DAN GRUPOS AMINO CARBAMILICOS SUSTITUIDOS O SIMPLES, O GRUPOS AMINO TIOCARBAMILICOS SUSTITUIDOS, O GRUPOS GUANIDINO POSIBLEMENTE SUSTITUIDOS, Y PROCESO PARA SU PRODUCCION. LOS I. ALERGICOS ASI MODIFICADOS NO ESTAN POLIMERIZADOS CON EL RESTO, SON SOLUBLES EN MEDIO ACUATICO, SON RESISTENTES A LA HIDROLISIS TRIPTICA Y MUESTRAN PARTICULARMENTE CAPACIDAD PARA SER ADMINISTRADOS EN TRATAMIENTOS DE HIPOSENSIBILIZACION TERAPEUTICA.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT04843189A IT1237475B (it) | 1989-10-06 | 1989-10-06 | Allergeni modificati chimicamente e procedimento per la loro preparazione |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2067725T3 true ES2067725T3 (es) | 1995-04-01 |
Family
ID=11266497
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES90830412T Expired - Lifetime ES2067725T3 (es) | 1989-10-06 | 1990-09-19 | Alergenos modificados quimicamente y procedimiento para su preparacion. |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US5354848A (es) |
| EP (1) | EP0421949B1 (es) |
| JP (1) | JPH0764874B2 (es) |
| AT (1) | ATE114477T1 (es) |
| AU (1) | AU637404B2 (es) |
| CA (1) | CA2026610C (es) |
| DE (1) | DE69014541T2 (es) |
| DK (1) | DK0421949T3 (es) |
| ES (1) | ES2067725T3 (es) |
| HK (1) | HK1003979A1 (es) |
| IT (1) | IT1237475B (es) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6566386B2 (en) | 1993-08-09 | 2003-05-20 | Nippon Zoki Pharmaceutical Co., Ltd. | Immunomodulating and antiinflammatory agent |
| JP3193205B2 (ja) * | 1993-08-09 | 2001-07-30 | 日本臓器製薬株式会社 | 好酸球増多抑制剤 |
| JPH0959180A (ja) | 1995-08-11 | 1997-03-04 | Nippon Zoki Pharmaceut Co Ltd | 活性化免疫グロブリン |
| JPH10212246A (ja) | 1997-01-30 | 1998-08-11 | Nippon Zoki Pharmaceut Co Ltd | 経口投与用製剤 |
| JP2000143536A (ja) | 1998-11-13 | 2000-05-23 | Nippon Zoki Pharmaceut Co Ltd | 抗浮腫剤 |
| US7142552B2 (en) * | 2002-04-08 | 2006-11-28 | International Business Machines Corporation | Method and system for priority enforcement with flow control |
| WO2006097120A1 (en) * | 2005-03-15 | 2006-09-21 | Tred Srl | A process for the preparation of hypoallergenic alimentary proteins |
| EP2140880B1 (en) | 2008-07-04 | 2012-11-14 | HAL Allergy Holding B.V. | Modification of allergens |
| IT1391559B1 (it) * | 2008-09-01 | 2012-01-11 | Lofarma Spa | Allergoidi derivati da allergeni |
| EP2239569A1 (en) | 2009-04-09 | 2010-10-13 | Lophius Biosciences GmbH | Method for polypeptide transfer into cells |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3893993A (en) * | 1969-08-06 | 1975-07-08 | Beecham Group Ltd | Allergenic extracts cross linked under acid conditions with inorganic cyanates |
| GB1282163A (en) * | 1969-08-06 | 1972-07-19 | Beecham Group Ltd | Modified allergens and a process for their preparation |
| US3761585A (en) * | 1971-04-05 | 1973-09-25 | Beecham Group Ltd | Vaccines containing modified allergenic material |
| US4222907A (en) * | 1978-09-25 | 1980-09-16 | Scripps Clinic & Research Foundation | Induction of immunological tolerance |
| US4234569A (en) * | 1978-10-04 | 1980-11-18 | The Johns Hopkins University | Production of aldehyde-treated allergen-containing substances |
| US4469677A (en) * | 1980-02-19 | 1984-09-04 | Michael J Gabriel | Polypeptide active immunosuppressant fraction |
| US4629706A (en) * | 1982-02-01 | 1986-12-16 | Miles Laboratories, Inc. | Method for determining allergic sensitivity |
-
1989
- 1989-10-06 IT IT04843189A patent/IT1237475B/it active IP Right Grant
-
1990
- 1990-09-19 DK DK90830412.4T patent/DK0421949T3/da active
- 1990-09-19 DE DE69014541T patent/DE69014541T2/de not_active Expired - Lifetime
- 1990-09-19 AT AT90830412T patent/ATE114477T1/de not_active IP Right Cessation
- 1990-09-19 EP EP90830412A patent/EP0421949B1/en not_active Expired - Lifetime
- 1990-09-19 ES ES90830412T patent/ES2067725T3/es not_active Expired - Lifetime
- 1990-09-26 AU AU63155/90A patent/AU637404B2/en not_active Expired
- 1990-09-26 US US07/588,344 patent/US5354848A/en not_active Expired - Lifetime
- 1990-10-01 CA CA002026610A patent/CA2026610C/en not_active Expired - Lifetime
- 1990-10-05 JP JP2268253A patent/JPH0764874B2/ja not_active Expired - Lifetime
-
1998
- 1998-04-16 HK HK98103177A patent/HK1003979A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| IT1237475B (it) | 1993-06-07 |
| EP0421949A1 (en) | 1991-04-10 |
| CA2026610C (en) | 2000-01-04 |
| ATE114477T1 (de) | 1994-12-15 |
| DE69014541T2 (de) | 1995-06-22 |
| HK1003979A1 (en) | 1998-11-13 |
| IT8948431A0 (it) | 1989-10-06 |
| CA2026610A1 (en) | 1991-04-07 |
| US5354848A (en) | 1994-10-11 |
| EP0421949B1 (en) | 1994-11-30 |
| DK0421949T3 (da) | 1995-05-08 |
| AU6315590A (en) | 1991-04-11 |
| JPH0764874B2 (ja) | 1995-07-12 |
| DE69014541D1 (de) | 1995-01-12 |
| JPH03151400A (ja) | 1991-06-27 |
| AU637404B2 (en) | 1993-05-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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