DE69014541T2 - Chemisch modifizierte Allergene und Verfahren zu ihrer Herstellung. - Google Patents

Chemisch modifizierte Allergene und Verfahren zu ihrer Herstellung.

Info

Publication number
DE69014541T2
DE69014541T2 DE69014541T DE69014541T DE69014541T2 DE 69014541 T2 DE69014541 T2 DE 69014541T2 DE 69014541 T DE69014541 T DE 69014541T DE 69014541 T DE69014541 T DE 69014541T DE 69014541 T2 DE69014541 T2 DE 69014541T2
Authority
DE
Germany
Prior art keywords
chemically modified
amino groups
production
allergens
substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69014541T
Other languages
English (en)
Other versions
DE69014541D1 (de
Inventor
Paolo Falagiani
Oreste Brenna
Giovanni Mistrello
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lofarma SpA
Original Assignee
LOFARMA FARMA LAB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by LOFARMA FARMA LAB filed Critical LOFARMA FARMA LAB
Publication of DE69014541D1 publication Critical patent/DE69014541D1/de
Application granted granted Critical
Publication of DE69014541T2 publication Critical patent/DE69014541T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/35—Allergens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/35—Allergens
    • A61K39/36—Allergens from pollen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/806—Antigenic peptides or proteins

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
DE69014541T 1989-10-06 1990-09-19 Chemisch modifizierte Allergene und Verfahren zu ihrer Herstellung. Expired - Lifetime DE69014541T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT04843189A IT1237475B (it) 1989-10-06 1989-10-06 Allergeni modificati chimicamente e procedimento per la loro preparazione

Publications (2)

Publication Number Publication Date
DE69014541D1 DE69014541D1 (de) 1995-01-12
DE69014541T2 true DE69014541T2 (de) 1995-06-22

Family

ID=11266497

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69014541T Expired - Lifetime DE69014541T2 (de) 1989-10-06 1990-09-19 Chemisch modifizierte Allergene und Verfahren zu ihrer Herstellung.

Country Status (11)

Country Link
US (1) US5354848A (de)
EP (1) EP0421949B1 (de)
JP (1) JPH0764874B2 (de)
AT (1) ATE114477T1 (de)
AU (1) AU637404B2 (de)
CA (1) CA2026610C (de)
DE (1) DE69014541T2 (de)
DK (1) DK0421949T3 (de)
ES (1) ES2067725T3 (de)
HK (1) HK1003979A1 (de)
IT (1) IT1237475B (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6566386B2 (en) 1993-08-09 2003-05-20 Nippon Zoki Pharmaceutical Co., Ltd. Immunomodulating and antiinflammatory agent
JP3193205B2 (ja) * 1993-08-09 2001-07-30 日本臓器製薬株式会社 好酸球増多抑制剤
JPH0959180A (ja) 1995-08-11 1997-03-04 Nippon Zoki Pharmaceut Co Ltd 活性化免疫グロブリン
JPH10212246A (ja) 1997-01-30 1998-08-11 Nippon Zoki Pharmaceut Co Ltd 経口投与用製剤
JP2000143536A (ja) 1998-11-13 2000-05-23 Nippon Zoki Pharmaceut Co Ltd 抗浮腫剤
US7142552B2 (en) * 2002-04-08 2006-11-28 International Business Machines Corporation Method and system for priority enforcement with flow control
WO2006097120A1 (en) * 2005-03-15 2006-09-21 Tred Srl A process for the preparation of hypoallergenic alimentary proteins
EP2140880B1 (de) 2008-07-04 2012-11-14 HAL Allergy Holding B.V. Modifikation von Allergenen
IT1391559B1 (it) * 2008-09-01 2012-01-11 Lofarma Spa Allergoidi derivati da allergeni
EP2239569A1 (de) 2009-04-09 2010-10-13 Lophius Biosciences GmbH Verfahren zur Übertragung von Polypeptiden in Zellen

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1282163A (en) * 1969-08-06 1972-07-19 Beecham Group Ltd Modified allergens and a process for their preparation
US3893993A (en) * 1969-08-06 1975-07-08 Beecham Group Ltd Allergenic extracts cross linked under acid conditions with inorganic cyanates
US3761585A (en) * 1971-04-05 1973-09-25 Beecham Group Ltd Vaccines containing modified allergenic material
US4222907A (en) * 1978-09-25 1980-09-16 Scripps Clinic & Research Foundation Induction of immunological tolerance
US4234569A (en) * 1978-10-04 1980-11-18 The Johns Hopkins University Production of aldehyde-treated allergen-containing substances
US4469677A (en) * 1980-02-19 1984-09-04 Michael J Gabriel Polypeptide active immunosuppressant fraction
US4629706A (en) * 1982-02-01 1986-12-16 Miles Laboratories, Inc. Method for determining allergic sensitivity

Also Published As

Publication number Publication date
CA2026610A1 (en) 1991-04-07
US5354848A (en) 1994-10-11
EP0421949B1 (de) 1994-11-30
JPH03151400A (ja) 1991-06-27
JPH0764874B2 (ja) 1995-07-12
DE69014541D1 (de) 1995-01-12
IT1237475B (it) 1993-06-07
EP0421949A1 (de) 1991-04-10
DK0421949T3 (da) 1995-05-08
AU637404B2 (en) 1993-05-27
HK1003979A1 (en) 1998-11-13
ATE114477T1 (de) 1994-12-15
CA2026610C (en) 2000-01-04
ES2067725T3 (es) 1995-04-01
AU6315590A (en) 1991-04-11
IT8948431A0 (it) 1989-10-06

Similar Documents

Publication Publication Date Title
ATE170630T1 (de) Proteine mit geänderten epitopen und verfahren zur deren herstellung
ATE135375T1 (de) Glykosaminoglykan-modifiertes protein, verfahren zu dessen herstellung und pharmazeutische zubereitungen, die es enthalten
NL300062I2 (nl) Osteogene middelen.
DE68919246T2 (de) Verfahren zur Herstellung von Aminosäuren.
DE69129899D1 (de) Verfahren zur Herstellung von D-Alpha-Aminosäuren
DE69014541T2 (de) Chemisch modifizierte Allergene und Verfahren zu ihrer Herstellung.
KR900002795A (ko) 하이브리드 단백질c 작제물 및 그들의 제조방법
DE68918279T2 (de) Plasminogenaktivator-varianten und verfahren zu ihrer herstellung.
FI893681A (fi) N-2,3-butadienyltri- och tetra-aminoalkanderivat.
DE3856240T2 (de) Herstellung der p1 proteine und impfstoffe gegen gonorrhöe
ATE80406T1 (de) Biologisch aktive topische kollagentraegermatrix: kosmetische und pharmazeutische verwendung und verfahren zu deren herstellung.
ATE119914T1 (de) Peptide, deren verwendung als immuno- suppressanten und verfahren zu deren herstellung.
ATE96280T1 (de) Verfahren zur herstellung eines pflanzlichen eiweisshydrolysats und so hergestelltes produkt.
PT90739A (pt) Processo para a preparacao de uma proteina dotada de actividade de inibicao de trombina
NO890174L (no) Rekombinante interleukin-1alfa-polypeptider.
ATE141645T1 (de) In vitro-behandlung von fusionsproteinen
ES544175A0 (es) Un procedimiento para preparar un material polimero hidrofilo basado en polisacaridos polipeptidos y -o proteinas y derivados acrilicos hidrofilos.
PT88913A (pt) Processo para a preparacao da proteina pp4-x anticoagulante
EP0038153A3 (de) Modifizierte Allergene
ATE110775T1 (de) Verfahren zur herstellung von hirudin.
ATE6639T1 (de) Ein gereinigtes polypeptid, ein verfahren zu dessen herstellung, dessen anwendung und das enthaltende pharmazeutische praeparat.
ATA901889A (de) Verfahren zur herstellung von wasserlöslichem primycin und seinen komponenten sowie von diese enthaltenden pharmazeutischen präparaten
DK0741746T3 (da) Thymosin alpha 1-analoger

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: LOFARMA S.P.A., MAILAND/MILANO, IT MELILLO, GAETAN

8328 Change in the person/name/address of the agent

Free format text: MITSCHERLICH & PARTNER, PATENT- UND RECHTSANWAELTE, 80331 MUENCHEN