ES2067254T3 - Oxisulfonilcarbamatos. - Google Patents

Oxisulfonilcarbamatos.

Info

Publication number
ES2067254T3
ES2067254T3 ES91920380T ES91920380T ES2067254T3 ES 2067254 T3 ES2067254 T3 ES 2067254T3 ES 91920380 T ES91920380 T ES 91920380T ES 91920380 T ES91920380 T ES 91920380T ES 2067254 T3 ES2067254 T3 ES 2067254T3
Authority
ES
Spain
Prior art keywords
compounds
formula
carbon atoms
naphthyl
phenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91920380T
Other languages
English (en)
Inventor
Joseph Armand Picard
Drago Robert Sliskovic
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Warner Lambert Co LLC
Original Assignee
Warner Lambert Co LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co LLC filed Critical Warner Lambert Co LLC
Application granted granted Critical
Publication of ES2067254T3 publication Critical patent/ES2067254T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C333/00—Derivatives of thiocarbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C333/02—Monothiocarbamic acids; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C333/00—Derivatives of thiocarbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C333/02—Monothiocarbamic acids; Derivatives thereof
    • C07C333/12—Monothiocarbamic acids; Derivatives thereof having nitrogen atoms of thiocarbamic groups bound to other hetero atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C307/00—Amides of sulfuric acids, i.e. compounds having singly-bound oxygen atoms of sulfate groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C307/02—Monoamides of sulfuric acids or esters thereof, e.g. sulfamic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)
  • Surgical Instruments (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

Un compuesto de fórmula(Ver fórmula)en donde:X es oxígeno o azufre;R es hidrógeno, un grupo alquilo lineal o ramificado que tiene de 1 a 8 átomos de carbono o bencilo; cadauno de R1 y R2 se elige entre:(a) fenilo que está insustituido o sustituido con 1 a 3 sustituyentes elegidos entre:fenilo,un grupo alquilo de 1 a 6 átomos de carbono y de cadena lineal o ramificada,un grupo alcoxi de 1 a 6 átomos de carbono y de cadena lineal o ramificada,fenoxi,hidroxi,flúor,cloro,bromo,trifluormetilo,-COOH,-COO alquilo en donde el alquilo tiene de 1 a 4 átomos de carbono y es de cadena lineal o ramificada,-(CH2)pNR3R4 en donde p es 0 o 1 y cada uno de R3 y R4 se elige entre hidrógeno o un grupo alquilolineal o ramificado que tiene de 1 a 4 átomos de carbono;(b)...
ES91920380T 1990-10-30 1991-10-02 Oxisulfonilcarbamatos. Expired - Lifetime ES2067254T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US60600690A 1990-10-30 1990-10-30
US73877291A 1991-08-01 1991-08-01

Publications (1)

Publication Number Publication Date
ES2067254T3 true ES2067254T3 (es) 1995-03-16

Family

ID=27085111

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91920380T Expired - Lifetime ES2067254T3 (es) 1990-10-30 1991-10-02 Oxisulfonilcarbamatos.

Country Status (16)

Country Link
EP (1) EP0555351B1 (es)
JP (1) JP3541384B2 (es)
KR (1) KR100193743B1 (es)
AT (1) ATE116291T1 (es)
AU (1) AU654688B2 (es)
CA (1) CA2093510C (es)
DE (1) DE69106386T2 (es)
DK (1) DK0555351T3 (es)
ES (1) ES2067254T3 (es)
FI (1) FI112358B (es)
GR (1) GR3014992T3 (es)
IE (1) IE65912B1 (es)
NO (1) NO179445C (es)
NZ (1) NZ240404A (es)
PT (1) PT99360B (es)
WO (1) WO1992007826A1 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL109431A (en) * 1993-05-14 2001-01-11 Warner Lambert Co Pharmaceutical compositions containing n-acyl sulfamic acid esters (or thioesters), n-acyl sulfonamides, and n-sulfonyl carbamic acid esters (or thioesters), for regulating plasma cholesterol concentration, and certain such novel compounds
US5491172A (en) * 1993-05-14 1996-02-13 Warner-Lambert Company N-acyl sulfamic acid esters (or thioesters), N-acyl sulfonamides, and N-sulfonyl carbamic acid esters (or thioesters) as hypercholesterolemic agents
KR19990036127A (ko) * 1995-08-03 1999-05-25 로즈 암스트롱 지방단백질의 농도를 감소시키는 의약의 제조를 위한 술팜산 유도체, 아실 술폰아미드 또는 술포닐 카르바메이트의 용도
US6093744A (en) * 1997-04-21 2000-07-25 Warner-Lambert Company N-acyl sulfamic acid esters useful as hypocholesterolemic agents
IL149145A0 (en) * 1999-11-05 2002-11-10 Warner Lambert Co Prevention of plaque rupture by acat inhibitors
KR100522446B1 (ko) * 2003-01-07 2005-10-18 한국생명공학연구원 아실 코에이:콜레스테롤 아실 트란스퍼라제의 저해활성을갖는 화합물 또는 그 염을 유효성분으로 하는 살충제
DE102014226666B3 (de) 2014-12-19 2015-12-24 Voith Patent Gmbh Stellantrieb für ein Regelventil, insbesondere Dampfturbinenregelventil und Verfahren zum Betreiben desselben

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE940292C (de) * 1952-07-01 1956-03-15 Hoechst Ag Verfahren zur Herstellung von Stickstoff und Schwefel enthaltenden Kondensationsprodukten
US3853953A (en) * 1970-02-11 1974-12-10 Hoffmann La Roche Alkyl (n-phenylsulfonyloxy) carbamates
PT65664B (en) * 1975-10-02 1978-04-12 Stauffer Chemical Co Process for obtention of new n-(benzenesulfonyl) thiocarbamates with herbicidal antidotes
GB1576314A (en) * 1976-02-27 1980-10-08 Ici Ltd Process for the crosslinking or chainextension of polymers

Also Published As

Publication number Publication date
NO931572D0 (no) 1993-04-29
EP0555351A1 (en) 1993-08-18
KR100193743B1 (ko) 1999-06-15
FI112358B (fi) 2003-11-28
PT99360B (pt) 1999-03-31
JP3541384B2 (ja) 2004-07-07
IE913774A1 (en) 1992-05-22
NO931572L (no) 1993-04-29
FI931838A (fi) 1993-04-23
NO179445B (no) 1996-07-01
DE69106386D1 (en) 1995-02-09
KR930702285A (ko) 1993-09-08
ATE116291T1 (de) 1995-01-15
CA2093510A1 (en) 1992-05-01
DE69106386T2 (de) 1995-05-04
WO1992007826A1 (en) 1992-05-14
GR3014992T3 (en) 1995-05-31
FI931838A0 (fi) 1993-04-23
PT99360A (pt) 1992-09-30
AU654688B2 (en) 1994-11-17
IE65912B1 (en) 1995-11-29
NZ240404A (en) 1994-02-25
NO179445C (no) 1996-10-09
EP0555351B1 (en) 1994-12-28
JPH06502415A (ja) 1994-03-17
CA2093510C (en) 2003-06-10
AU8937091A (en) 1992-05-26
DK0555351T3 (da) 1995-06-06

Similar Documents

Publication Publication Date Title
PT99436A (pt) Processo para a preparacao de derivados de amino-sulfonil-carbamatos e de com- posicoes farmaceuticas que os contem
ES525358A0 (es) Procedimiento para la fabricacion de 4-(3-trifluorometilfenil)-1,2,3,6-tetrahidropiridinas
DE3483861D1 (de) Oliglucosidderivate.
NO165921C (no) Fremgangsmaate for fremstilling av disubstituerte prolinderivater.
DE69106386T2 (de) Oxysulfonylcarbamate.
MX9301045A (es) Procedimiento para preparar antagonistas receptores de fibrinogeno.
DE69107217T2 (de) Oxysulfonylharnstoff-acat-inhibitoren.
YU47010B (sh) Derivati 1,6-naftiridina
DK439384D0 (da) Derivater af 4-(3-alkynyloxy-2-hydroxypropyl)-piperazin-1-yl-n-phenylacetamid, fremgangsmaade til fremstilling deraf samt farmaceutisk middel indeholdende disse
HUT61967A (en) Process for producing new alkyl aminoalkyl amine- and -ether derivatives and pharmaceutical compositions comprising such compounds
PT92494A (pt) Processo para a preparacao de novos derivados do indol
ES545617A0 (es) Procedimiento para la preparacion de derivados de carboci- clina
AR247737A1 (es) Un procedimiento para la fabricacion de compuestos.
DK0599732T3 (da) 1-phenylbicyklo 2.2.2 octanderivater, fremgangsmåde til fremstilling heraf og farmaceutiske midler, som indeholder dem.
IT1210914B (it) Eterociclilfenilsolfonil e fosfonilamidine sostituite, procedimento per la loro preparazione e loro uso farmaceutico.
ES460516A3 (es) Procedimiento para la obtencion de isotioureas.
ES469955A1 (es) Un procedimiento para la preparacion de derivados de 2-naf- tilamina

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 555351

Country of ref document: ES