ES2063513T3 - Nuevos derivados del oxazol, su preparacion y las composiciones farmaceuticas que les contienen. - Google Patents

Nuevos derivados del oxazol, su preparacion y las composiciones farmaceuticas que les contienen.

Info

Publication number
ES2063513T3
ES2063513T3 ES91912243T ES91912243T ES2063513T3 ES 2063513 T3 ES2063513 T3 ES 2063513T3 ES 91912243 T ES91912243 T ES 91912243T ES 91912243 T ES91912243 T ES 91912243T ES 2063513 T3 ES2063513 T3 ES 2063513T3
Authority
ES
Spain
Prior art keywords
pct
preparation
oxazole
contain
pharmaceutical compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91912243T
Other languages
English (en)
Inventor
Michel Barreau
Michel Kryvenko
Marc Pierre Lavergne
Auguste Techer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratoire Roger Bellon SA
Original Assignee
Laboratoire Roger Bellon SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoire Roger Bellon SA filed Critical Laboratoire Roger Bellon SA
Application granted granted Critical
Publication of ES2063513T3 publication Critical patent/ES2063513T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pain & Pain Management (AREA)
  • Animal Behavior & Ethology (AREA)
  • Rheumatology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

NUEVOS DERIVADOS DE OXAZOL DE FORMULA GENERAL (I), EN LA QUE : R Y R'' SON HIDROGENO O ALKILO QUE CONTIENE 1 O 2 ATOMOS DE CARBONO, R1 Y R2 SON IDENTICOS O DIFERENTES Y REPRESENTAN HIDROGENO, HALOGENO O RADICALES ALKILOXI (1 A 4C) EN CADENA RECTA O RAMIFICADA, Y N IGUAL A 3 O 6, ASI COMO SUS SALES , CUANDO EXISTEN, SUS ISOMEROS Y SUS MEZCLAS, Y SU PREPARACION. ESTOS PRODUCTOS MANIFIESTAN UNA ACTIVIDAD ANTIINFLAMATORIA.
ES91912243T 1990-06-14 1991-06-13 Nuevos derivados del oxazol, su preparacion y las composiciones farmaceuticas que les contienen. Expired - Lifetime ES2063513T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9007388A FR2663331B1 (fr) 1990-06-14 1990-06-14 Nouveaux derives de l'oxazole, leur preparation et les compositions pharmaceutiques qui les contiennent.

Publications (1)

Publication Number Publication Date
ES2063513T3 true ES2063513T3 (es) 1995-01-01

Family

ID=9397581

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91912243T Expired - Lifetime ES2063513T3 (es) 1990-06-14 1991-06-13 Nuevos derivados del oxazol, su preparacion y las composiciones farmaceuticas que les contienen.

Country Status (21)

Country Link
US (1) US5403852A (es)
EP (1) EP0533827B1 (es)
JP (1) JPH05507710A (es)
KR (1) KR930700493A (es)
AT (1) ATE110381T1 (es)
AU (1) AU644454B2 (es)
CA (1) CA2080340A1 (es)
CS (1) CS180191A3 (es)
DE (1) DE69103630T2 (es)
DK (1) DK0533827T3 (es)
ES (1) ES2063513T3 (es)
FI (1) FI925191A (es)
FR (1) FR2663331B1 (es)
HU (1) HUT62888A (es)
IE (1) IE912019A1 (es)
IL (1) IL98488A0 (es)
NO (1) NO924634L (es)
NZ (1) NZ238524A (es)
PT (1) PT97974A (es)
WO (1) WO1991019714A1 (es)
ZA (1) ZA914516B (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5380738A (en) * 1993-05-21 1995-01-10 Monsanto Company 2-substituted oxazoles further substituted by 4-fluorophenyl and 4-methylsulfonylphenyl as antiinflammatory agents
US6090834A (en) * 1993-05-21 2000-07-18 G.D. Searle & Co. Substituted oxazoles for the treatment of inflammation
EP0825989A1 (en) * 1995-05-19 1998-03-04 G.D. Searle & Co. Substituted oxazoles for the treatment of inflammation
US5942530A (en) * 1997-08-28 1999-08-24 Eli Lilly And Company Method for treating pain
US5952360A (en) * 1997-08-28 1999-09-14 Eli Lilly And Company Method for treating neuropathic pain
US7358254B2 (en) 2001-07-13 2008-04-15 Bristol-Myers Squibb Company Method for treating atherosclerosis employing an aP2 inhibitor and combination
BR9913833A (pt) 1998-09-17 2001-05-29 Bristol Myers Squibb Co Método para tratar diabetes, empregando em inibidor de ap2 e combinação
US7390824B1 (en) 1999-09-07 2008-06-24 Bristol-Myers Squibb Company Method for treating diabetes employing an aP2 inhibitor and combination
FR2800373B1 (fr) * 1999-10-27 2001-12-07 Oreal Procede de preparation d'oxazoles trisubstitues
TW200505446A (en) * 2003-01-17 2005-02-16 Fuj Isawa Pharmaceutical Co Ltd Inhibitor of cox
JP5912946B2 (ja) * 2012-01-11 2016-04-27 株式会社Adeka 感光性樹脂組成物

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1206403A (en) * 1966-12-15 1970-09-23 Wyeth John & Brother Ltd Oxazoles
US3546342A (en) * 1966-11-18 1970-12-08 Wyeth John & Brother Ltd Method of relieving inflammation by administration of 2,4 - diarylthiazole- 5 - alkanoic acids and derivatives thereof
FI53314C (fi) * 1967-06-14 1978-04-10 Wyeth John & Brother Ltd Foerfarande foer framstaellning av farmaceutiskt anvaendbar 2-(fenyleller p-klorfenyl) oxazol-4-yl (aettiksyra -acetatsalt eller -acetamid)
US3586679A (en) * 1968-11-21 1971-06-22 Ciba Geigy Corp Process for the production of 2,4-dichloro-6-amino-s-triazines
GB1381860A (en) * 1971-06-03 1975-01-29 Wyeth John & Brother Ltd Tetrazole derivatives
DE2129012A1 (de) * 1971-06-11 1973-01-04 Merck Patent Gmbh Azol-derivate
GB1373352A (en) * 1972-04-27 1974-11-13 Wyeth John & Brother Ltd Oxazole derivatives
US5262540A (en) * 1989-12-20 1993-11-16 Bristol-Myers Squibb Company [2(4,5-diaryl-2 oxazoyl substituted phenoxy alkanoic acid and esters

Also Published As

Publication number Publication date
DK0533827T3 (da) 1994-09-26
ATE110381T1 (de) 1994-09-15
PT97974A (pt) 1992-03-31
AU8058391A (en) 1992-01-07
JPH05507710A (ja) 1993-11-04
DE69103630T2 (de) 1995-01-12
FI925191A0 (fi) 1992-11-16
FR2663331A1 (fr) 1991-12-20
CS180191A3 (en) 1992-02-19
CA2080340A1 (fr) 1991-12-15
EP0533827B1 (fr) 1994-08-24
NZ238524A (en) 1992-07-28
FI925191A (fi) 1992-11-16
HU9203942D0 (en) 1993-03-29
IE912019A1 (en) 1991-12-18
NO924634D0 (no) 1992-12-01
ZA914516B (en) 1992-03-25
US5403852A (en) 1995-04-04
WO1991019714A1 (fr) 1991-12-26
KR930700493A (ko) 1993-03-15
DE69103630D1 (de) 1994-09-29
EP0533827A1 (fr) 1993-03-31
AU644454B2 (en) 1993-12-09
NO924634L (no) 1992-12-01
FR2663331B1 (fr) 1994-05-06
HUT62888A (en) 1993-06-28
IL98488A0 (en) 1992-07-15

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