ES2062724T3 - Utilizacion de derivados de la triazina y de la pirimidina para la obtencion de medicamentos que combaten la resistencia a los agentes anticancerosos y antimalaricos. - Google Patents

Utilizacion de derivados de la triazina y de la pirimidina para la obtencion de medicamentos que combaten la resistencia a los agentes anticancerosos y antimalaricos.

Info

Publication number
ES2062724T3
ES2062724T3 ES91402472T ES91402472T ES2062724T3 ES 2062724 T3 ES2062724 T3 ES 2062724T3 ES 91402472 T ES91402472 T ES 91402472T ES 91402472 T ES91402472 T ES 91402472T ES 2062724 T3 ES2062724 T3 ES 2062724T3
Authority
ES
Spain
Prior art keywords
agents
antimalaric
triazine
cancer
resistance
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91402472T
Other languages
English (en)
Inventor
Bernard Paramelle
Xavier Leverve
Gilbert Regnier
Alain Dhainaut
Ghanem Atassi
Alain Pierre
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ADIR SARL
Original Assignee
ADIR SARL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ADIR SARL filed Critical ADIR SARL
Application granted granted Critical
Publication of ES2062724T3 publication Critical patent/ES2062724T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

LA INVENCION SE REFIERE A LA UTILIZACION PARA LA OBTENCION DE MEDICAMENTOS QUE TRANSFIEREN LA RESISTENCIA A LOS AGENTES ANTICANCERIGENOS Y ANTIMALARICOS DE COMPUESTOS DE FORMULA (I): EN LA QUE LAS DESCRIPCIONES, ASI COMO SUS SALES DE ADICION DE ACIDOS FISIOLOGICAMENTE TOLERABLES.
ES91402472T 1990-09-27 1991-09-18 Utilizacion de derivados de la triazina y de la pirimidina para la obtencion de medicamentos que combaten la resistencia a los agentes anticancerosos y antimalaricos. Expired - Lifetime ES2062724T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9011887A FR2667243B1 (fr) 1990-09-27 1990-09-27 Utilisation de s derives de la triazine et de la pyrimidine pour l'obtention de medicaments reversant la resistance aux agents anticancereux et antimalariques.

Publications (1)

Publication Number Publication Date
ES2062724T3 true ES2062724T3 (es) 1994-12-16

Family

ID=9400676

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91402472T Expired - Lifetime ES2062724T3 (es) 1990-09-27 1991-09-18 Utilizacion de derivados de la triazina y de la pirimidina para la obtencion de medicamentos que combaten la resistencia a los agentes anticancerosos y antimalaricos.

Country Status (14)

Country Link
US (1) US5225405A (es)
EP (1) EP0478416B1 (es)
JP (1) JPH0761943B2 (es)
AT (1) ATE100711T1 (es)
AU (1) AU648584B2 (es)
CA (1) CA2052441A1 (es)
DE (1) DE69101097T2 (es)
DK (1) DK0478416T3 (es)
ES (1) ES2062724T3 (es)
FR (1) FR2667243B1 (es)
IE (1) IE65594B1 (es)
NZ (1) NZ239953A (es)
PT (1) PT99091B (es)
ZA (1) ZA917699B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1181702A (zh) * 1995-04-20 1998-05-13 日本新药株式会社 血管新生抑制剂
DE69701506T2 (de) 1996-08-13 2000-08-03 Kyowa Hakko Kogyo Co., Ltd. Tabletten auf basis von isotopenmarkiertem harnstoff
US6335339B1 (en) 1998-01-13 2002-01-01 Scriptgen Pharmaceuticals, Inc. Triazine antiviral compounds
US6693099B2 (en) 2000-10-17 2004-02-17 The Procter & Gamble Company Substituted piperazine compounds optionally containing a quinolyl moiety for treating multidrug resistance
US6376514B1 (en) * 2000-10-17 2002-04-23 The Procter & Gamble Co. Substituted six-membered heterocyclic compounds useful for treating multidrug resistance and compositions and methods thereof
SG11202000331YA (en) * 2017-07-13 2020-02-27 Michael David Forrest Therapeutic modulators of the reverse mode of atp synthase

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1256513A (es) * 1968-10-02 1971-12-08
FR2521560A1 (fr) * 1982-02-17 1983-08-19 Adir Nouveaux derives de piperazine et d'homopiperazine, leurs procedes de preparation et les compositions pharmaceutiques les renfermant
FR2524467A1 (fr) * 1982-03-30 1983-10-07 Adir Polymethylene-imines disubstituees, leurs procedes de preparation et les compositions pharmaceutiques les renfermant
FR2525597B1 (fr) * 1982-04-21 1985-06-07 Adir Polymethylene diamines n,n'-substituees, leurs procedes de preparation et les compositions pharmaceutiques les renfermant
FR2544315B1 (fr) * 1983-04-12 1985-07-05 Adir Polymethylene imines disubstituees, leurs procedes de preparation, et les compositions pharmaceutiques les renfermant

Also Published As

Publication number Publication date
DE69101097T2 (de) 1994-08-04
CA2052441A1 (fr) 1992-03-28
JPH0672878A (ja) 1994-03-15
ZA917699B (en) 1992-06-24
AU648584B2 (en) 1994-04-28
PT99091B (pt) 1999-02-26
EP0478416B1 (fr) 1994-01-26
ATE100711T1 (de) 1994-02-15
NZ239953A (en) 1997-06-24
JPH0761943B2 (ja) 1995-07-05
FR2667243B1 (fr) 1994-11-04
US5225405A (en) 1993-07-06
PT99091A (pt) 1992-08-31
AU8475291A (en) 1992-04-02
FR2667243A1 (fr) 1992-04-03
DK0478416T3 (da) 1994-05-02
EP0478416A1 (fr) 1992-04-01
IE913375A1 (en) 1992-04-08
IE65594B1 (en) 1995-11-01
DE69101097D1 (de) 1994-03-10

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