ES2061554T3 - Estabilizacion de productos biologicos y farmaceuticos durante la inactivacion de contaminantes viricos y bacterianos. - Google Patents

Estabilizacion de productos biologicos y farmaceuticos durante la inactivacion de contaminantes viricos y bacterianos.

Info

Publication number
ES2061554T3
ES2061554T3 ES88108131T ES88108131T ES2061554T3 ES 2061554 T3 ES2061554 T3 ES 2061554T3 ES 88108131 T ES88108131 T ES 88108131T ES 88108131 T ES88108131 T ES 88108131T ES 2061554 T3 ES2061554 T3 ES 2061554T3
Authority
ES
Spain
Prior art keywords
biological
viric
inactivation
stabilization
aqueous solution
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES88108131T
Other languages
English (en)
Inventor
Fred Feldman
Mark S Klekamp
Michael E Hrinda
Arthur B Shaw
Sudhish Chandra
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Armour Pharmaceutical Co
Original Assignee
Armour Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Armour Pharmaceutical Co filed Critical Armour Pharmaceutical Co
Application granted granted Critical
Publication of ES2061554T3 publication Critical patent/ES2061554T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
    • A61L2/0023—Heat
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

UN METODO DE INACTIVAR PATOGENOS EN UN MATERIAL BIOLOGICO O FARMACEUTICO COMPRENDIENDO LOS PASOS DE: MEZCLAR EL MATERIAL EN UNA SOLUCION ACUOSA CONTENIENDO AL MENOS UNA PRIMERA ESTABILIZACION SELECTIVA DE AZUCARES O ALCOHOLES AZUCARADOS Y AL MENOS UNA SECUNDARIA ESTABILIZACION SELECTIVA DE GRUPOS CONSISTENTES DE SALES NEUTRAS; AJUSTE DEL PH DE LA SOLUCION ACUOSA ALREDEDOR DE 5,0 A 10,0; SOMETER LA SOLUCION ACUOSA AL PROCESO DE INACTIVACION PATOGENA; Y ELIMINACION OPCIONAL DE LOS ESTABILIZADORES PRIMARIO Y SECUNDARIO DE LA SOLUCION ACUOSA.
ES88108131T 1987-05-22 1988-05-20 Estabilizacion de productos biologicos y farmaceuticos durante la inactivacion de contaminantes viricos y bacterianos. Expired - Lifetime ES2061554T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US5292687A 1987-05-22 1987-05-22

Publications (1)

Publication Number Publication Date
ES2061554T3 true ES2061554T3 (es) 1994-12-16

Family

ID=21980809

Family Applications (1)

Application Number Title Priority Date Filing Date
ES88108131T Expired - Lifetime ES2061554T3 (es) 1987-05-22 1988-05-20 Estabilizacion de productos biologicos y farmaceuticos durante la inactivacion de contaminantes viricos y bacterianos.

Country Status (11)

Country Link
EP (1) EP0292003B1 (es)
JP (2) JP2605102B2 (es)
AT (1) ATE103185T1 (es)
AU (1) AU606159B2 (es)
CA (1) CA1337688C (es)
DE (1) DE3888571T2 (es)
ES (1) ES2061554T3 (es)
FI (1) FI95778C (es)
IL (1) IL86417A (es)
NO (1) NO176234C (es)
NZ (1) NZ224740A (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3619565A1 (de) * 1986-06-11 1987-12-17 Behringwerke Ag Verfahren zur herstellung einer pasteurisierten immunglobulinpraeparation
EP0440509A3 (en) * 1990-02-02 1991-12-18 Common Services Agency Novel cell growth medium components and process for producing same
AT402891B (de) * 1991-06-20 1997-09-25 Immuno Ag Verfahren zur herstellung eines inaktivierten blutproduktes
AT399818B (de) * 1992-04-24 1995-07-25 Immuno Ag Verfahren zur herstellung einer hochgereinigten virussicheren faktor viii-präparation
JP3133338B2 (ja) * 1992-12-16 2001-02-05 イムノ・アクチエンゲゼルシャフト ウイルス的に安全な生物学的組成物の調製方法
DE4320294A1 (de) * 1993-06-18 1994-12-22 Immuno Ag Verwendung von humanem Protein C zur Verhinderung und Behandlung von Thrombozytenablagerungen
HRP940645A2 (en) * 1993-10-06 1996-12-31 Immuno Ag Process for virus deactivation in the presence of polyalkylene glycol and the pharmaceutical preparation thus obtained
US5616693A (en) * 1996-07-01 1997-04-01 Alpha Therapeutic Corporation Process for seperating alpha-1-proteinase inhibitor from COHN IV1 +1V4 paste
RU2244556C2 (ru) 1999-02-22 2005-01-20 Юниверсити Оф Коннектикут Новые не содержащие альбумин составы фактора viii
AU2006256802A1 (en) * 2005-06-06 2006-12-14 Novo Nordisk A/S Stabilised IL-21 compositions
DE102006008613A1 (de) 2006-02-24 2007-08-30 Dade Behring Marburg Gmbh Stabilisierte Zubereitungen von Serin-Endopeptidasen, deren Herstellung und Verwendung
JP5779780B2 (ja) 2008-11-07 2015-09-16 バクスター・インターナショナル・インコーポレイテッドＢａｘｔｅｒ Ｉｎｔｅｒｎａｔｉｏｎａｌ Ｉｎｃｏｒｐ０Ｒａｔｅｄ 第ｖｉｉｉ因子製剤

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS53142593A (en) * 1977-12-12 1978-12-12 Green Cross Corp:The Stabilization of urokinase by heating
EP0035204B2 (en) * 1980-03-05 1991-05-22 Miles Inc. Pasteurized therapeutically active protein compositions
JPS56135418A (en) * 1980-03-27 1981-10-22 Green Cross Corp:The Heat treatment of aqueous solution containing 8 factor of coagulation of blood derived from human
DE3045153A1 (de) * 1980-11-29 1982-07-08 Behringwerke Ag, 3550 Marburg Verfahren zur herstellung von blutgerinnungsfaktoren und danach hergestellte praeparation der faktoren ix und x
JPS5874617A (ja) * 1981-10-28 1983-05-06 Green Cross Corp:The 人由来血液凝固第７因子含有水溶液の加熱処理方法
US4379085A (en) * 1982-05-14 1983-04-05 American National Red Cross Heat stabilization of plasma proteins
US4470968A (en) * 1983-01-13 1984-09-11 Miles Laboratories, Inc. Pasteurized therapeutically active blood coagulation factor concentrates
JPS59134730A (ja) * 1983-01-20 1984-08-02 Green Cross Corp:The 血液凝固第８因子の加熱処理法
CA1213827A (en) * 1983-04-29 1986-11-12 Ricardo H. Landaburu Process for pasteurizing fibronectin
JPH0669961B2 (ja) * 1984-09-25 1994-09-07 株式会社ミドリ十字 免疫グロブリンの加熱処理方法
JPS61189228A (ja) * 1985-02-19 1986-08-22 Nippon Sekijiyuujishiya 血液凝固第８因子製剤の製法
JPH0825902B2 (ja) * 1985-02-21 1996-03-13 株式会社ミドリ十字 γ−グロブリンの加熱処理方法
US4632980A (en) * 1985-04-03 1986-12-30 Immunologics Ozone decontamination of blood and blood products
JPS6289628A (ja) * 1985-09-11 1987-04-24 Green Cross Corp:The 人フイブリノゲン製剤の加熱処理法
JPS6281327A (ja) * 1985-10-04 1987-04-14 Green Cross Corp:The 人トロンビン製剤の加熱処理方法

Also Published As

Publication number Publication date
JPH09118634A (ja) 1997-05-06
IL86417A0 (en) 1988-11-15
JP2879427B2 (ja) 1999-04-05
JP2605102B2 (ja) 1997-04-30
NO176234B (no) 1994-11-21
JPS649937A (en) 1989-01-13
DE3888571D1 (de) 1994-04-28
EP0292003A3 (en) 1990-06-13
EP0292003B1 (en) 1994-03-23
AU1664288A (en) 1988-11-24
FI882387A0 (fi) 1988-05-20
AU606159B2 (en) 1991-01-31
FI95778C (fi) 1996-03-25
ATE103185T1 (de) 1994-04-15
IL86417A (en) 1992-09-06
CA1337688C (en) 1995-12-05
NO176234C (no) 1995-03-01
DE3888571T2 (de) 1994-08-11
FI882387A (fi) 1988-11-23
EP0292003A2 (en) 1988-11-23
NO882242D0 (no) 1988-05-20
FI95778B (fi) 1995-12-15
NZ224740A (en) 1990-01-29
NO882242L (no) 1988-11-23

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