ES2061030T3 - Sistema de tratamiento antitrombogenico de la sangre. - Google Patents
Sistema de tratamiento antitrombogenico de la sangre.Info
- Publication number
- ES2061030T3 ES2061030T3 ES90906364T ES90906364T ES2061030T3 ES 2061030 T3 ES2061030 T3 ES 2061030T3 ES 90906364 T ES90906364 T ES 90906364T ES 90906364 T ES90906364 T ES 90906364T ES 2061030 T3 ES2061030 T3 ES 2061030T3
- Authority
- ES
- Spain
- Prior art keywords
- blood
- treatment system
- contact surface
- polyethylene oxide
- unit
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000008280 blood Substances 0.000 title abstract 4
- 210000004369 blood Anatomy 0.000 title abstract 4
- 229920003171 Poly (ethylene oxide) Polymers 0.000 abstract 2
- 229920001480 hydrophilic copolymer Polymers 0.000 abstract 2
- -1 CHLORIDE VINYL Chemical class 0.000 abstract 1
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 abstract 1
- 230000002785 anti-thrombosis Effects 0.000 abstract 1
- 239000003146 anticoagulant agent Substances 0.000 abstract 1
- 239000000470 constituent Substances 0.000 abstract 1
- 229920001577 copolymer Polymers 0.000 abstract 1
- 239000000835 fiber Substances 0.000 abstract 1
- 229920000669 heparin Polymers 0.000 abstract 1
- 239000012528 membrane Substances 0.000 abstract 1
- 230000035699 permeability Effects 0.000 abstract 1
- 229920002554 vinyl polymer Polymers 0.000 abstract 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D71/00—Semi-permeable membranes for separation processes or apparatus characterised by the material; Manufacturing processes specially adapted therefor
- B01D71/06—Organic material
- B01D71/76—Macromolecular material not specifically provided for in a single one of groups B01D71/08 - B01D71/74
- B01D71/82—Macromolecular material not specifically provided for in a single one of groups B01D71/08 - B01D71/74 characterised by the presence of specified groups, e.g. introduced by chemical after-treatment
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L33/00—Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
- A61L33/0005—Use of materials characterised by their function or physical properties
- A61L33/0011—Anticoagulant, e.g. heparin, platelet aggregation inhibitor, fibrinolytic agent, other than enzymes, attached to the substrate
- A61L33/0029—Anticoagulant, e.g. heparin, platelet aggregation inhibitor, fibrinolytic agent, other than enzymes, attached to the substrate using an intermediate layer of polymer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L33/00—Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
- A61L33/06—Use of macromolecular materials
- A61L33/068—Use of macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3672—Means preventing coagulation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3672—Means preventing coagulation
- A61M1/3673—Anticoagulant coating, e.g. Heparin coating
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D63/00—Apparatus in general for separation processes using semi-permeable membranes
- B01D63/02—Hollow fibre modules
- B01D63/021—Manufacturing thereof
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D63/00—Apparatus in general for separation processes using semi-permeable membranes
- B01D63/02—Hollow fibre modules
- B01D63/021—Manufacturing thereof
- B01D63/0233—Manufacturing thereof forming the bundle
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D69/00—Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor
- B01D69/08—Hollow fibre membranes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D71/00—Semi-permeable membranes for separation processes or apparatus characterised by the material; Manufacturing processes specially adapted therefor
- B01D71/06—Organic material
- B01D71/30—Polyalkenyl halides
- B01D71/301—Polyvinylchloride
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D71/00—Semi-permeable membranes for separation processes or apparatus characterised by the material; Manufacturing processes specially adapted therefor
- B01D71/06—Organic material
- B01D71/40—Polymers of unsaturated acids or derivatives thereof, e.g. salts, amides, imides, nitriles, anhydrides, esters
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D71/00—Semi-permeable membranes for separation processes or apparatus characterised by the material; Manufacturing processes specially adapted therefor
- B01D71/06—Organic material
- B01D71/40—Polymers of unsaturated acids or derivatives thereof, e.g. salts, amides, imides, nitriles, anhydrides, esters
- B01D71/401—Polymers based on the polymerisation of acrylic acid, e.g. polyacrylate
- B01D71/4011—Polymethylmethacrylate
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D71/00—Semi-permeable membranes for separation processes or apparatus characterised by the material; Manufacturing processes specially adapted therefor
- B01D71/06—Organic material
- B01D71/52—Polyethers
- B01D71/521—Aliphatic polyethers
- B01D71/5211—Polyethylene glycol or polyethyleneoxide
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D71/00—Semi-permeable membranes for separation processes or apparatus characterised by the material; Manufacturing processes specially adapted therefor
- B01D71/06—Organic material
- B01D71/76—Macromolecular material not specifically provided for in a single one of groups B01D71/08 - B01D71/74
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/04—Liquids
- A61M2202/0413—Blood
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/02—General characteristics of the apparatus characterised by a particular materials
- A61M2205/0238—General characteristics of the apparatus characterised by a particular materials the material being a coating or protective layer
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2313/00—Details relating to membrane modules or apparatus
- B01D2313/13—Specific connectors
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D71/00—Semi-permeable membranes for separation processes or apparatus characterised by the material; Manufacturing processes specially adapted therefor
- B01D71/06—Organic material
- B01D71/30—Polyalkenyl halides
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D71/00—Semi-permeable membranes for separation processes or apparatus characterised by the material; Manufacturing processes specially adapted therefor
- B01D71/06—Organic material
- B01D71/52—Polyethers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Hematology (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Epidemiology (AREA)
- Surgery (AREA)
- Materials Engineering (AREA)
- Cardiology (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Manufacturing & Machinery (AREA)
- Materials For Medical Uses (AREA)
- External Artificial Organs (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
UN SISTEMA DE TRATAMIENTO DE SANGRE ANTITROMBOTICO QUE CONSTA DE UNA COMBINACION DE MEMBRANA DE FIBRA HUECA DE PERMEABILIDAD SELECTIVA QUE CONTIENE UN COPOLIMERO QUE TIENE UNA UNIDAD DE OXIDO DE POLIETILENO; UN COLECTOR QUE TIENE UNA SUPERFICIE DE CONTACTO DE SANGRE RECUBIERTA CON BIEN UN COPOLIMERO HIDROFILICO HEPARINIZADO QUE CONTIENE VINIL CLORIDO COMO SU PARTE CONSTITUYENTE O BIEN UN COPOLIMERO HIDROFILICO QUE TIENE UNA UNIDAD DE OXIDO DE POLIETILENO; UN CATETER; Y UN CIRCUITO. ELLO HACE POSIBLE POR PRIMERA VEZ CONDUCIR CIRCULACION EXTRACORPORAL DURANTE UN LARGO PERIODO DE TIEMPO SIN LA NECESIDAD DE ADMINISTRAR HEPARINA INTERNAMENTE IMPARTIENDO UNA PROPIEDAD ANTITROMBOTICA A TODA LA SUPERFICIE DE CONTACTO DE SANGRE.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP10619689 | 1989-04-25 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2061030T3 true ES2061030T3 (es) | 1994-12-01 |
Family
ID=14427423
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES90906364T Expired - Lifetime ES2061030T3 (es) | 1989-04-25 | 1990-04-25 | Sistema de tratamiento antitrombogenico de la sangre. |
Country Status (7)
Country | Link |
---|---|
US (1) | US5254249A (es) |
EP (1) | EP0423369B1 (es) |
KR (1) | KR920700048A (es) |
AT (1) | ATE112967T1 (es) |
DE (1) | DE69013457T2 (es) |
ES (1) | ES2061030T3 (es) |
WO (1) | WO1990012607A1 (es) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5182317A (en) * | 1988-06-08 | 1993-01-26 | Cardiopulmonics, Inc. | Multifunctional thrombo-resistant coatings and methods of manufacture |
US5338770A (en) * | 1988-06-08 | 1994-08-16 | Cardiopulmonics, Inc. | Gas permeable thrombo-resistant coatings and methods of manufacture |
JP2006124714A (ja) * | 1992-09-29 | 2006-05-18 | Toray Ind Inc | 耐汚染性材料および耐汚染性半透膜 |
JPH08506977A (ja) * | 1993-02-18 | 1996-07-30 | バクスター インターナショナル インコーポレーテッド | 抗凝固剤注入用の別の位置を含むアフェレーシスシステム |
SE502222C2 (sv) * | 1994-01-17 | 1995-09-18 | Althin Medical Ab | Sätt vid dialys |
WO1999023127A1 (fr) * | 1996-07-16 | 1999-05-14 | Toray Industries, Inc. | Polymere greffe et moulages realises a partir de celui-ci pour fournitures medicales |
US5891196A (en) * | 1997-04-16 | 1999-04-06 | Baxter International Inc. | Method for actively binding heparin to crosslinked biological tissues |
US5955353A (en) * | 1997-05-22 | 1999-09-21 | Excorp Medical, Inc. | Hollow fiber bioreactor with an extrafilament flow plug |
US5945457A (en) * | 1997-10-01 | 1999-08-31 | A.V. Topchiev Institute Of Petrochemical Synthesis, Russian Academy Of Science | Process for preparing biologically compatible polymers and their use in medical devices |
ATE451131T1 (de) * | 1999-01-12 | 2009-12-15 | Gambro Renal Products Inc | Gerät für dialyse mit erwärmung vom blut |
JP3940546B2 (ja) * | 1999-06-07 | 2007-07-04 | 株式会社東芝 | パターン形成方法およびパターン形成材料 |
JP4404445B2 (ja) * | 2000-05-17 | 2010-01-27 | テルモ株式会社 | 血液フィルターおよび血液フィルターの製造方法 |
JP2004008693A (ja) * | 2002-06-11 | 2004-01-15 | Toyobo Co Ltd | 血液適合性血液浄化システム |
US20050045554A1 (en) * | 2003-08-28 | 2005-03-03 | Gambro Lundia Ab | Membrane unit element, semipermeable membrane, filtration device, and processes for manufacturing the same |
JP4064898B2 (ja) * | 2003-09-03 | 2008-03-19 | ポリエン・プロジェクト有限会社 | 流体管路用接続装置 |
RU2646506C1 (ru) * | 2014-02-12 | 2018-03-05 | Торэй Индастриз, Инк. | Искусственный кровеносный сосуд |
US20160045932A1 (en) * | 2014-08-18 | 2016-02-18 | Fenwal, Inc. | Anti-Thrombogenic Porous Membranes And Methods For Manufacturing Such Membranes |
WO2017154527A1 (ja) * | 2016-03-08 | 2017-09-14 | テルモ株式会社 | 医療用具 |
JP7242167B2 (ja) * | 2016-09-30 | 2023-03-20 | 東レ株式会社 | 血液処理装置 |
US11672898B2 (en) | 2018-06-08 | 2023-06-13 | Oregon State University | Microfluidic removal of excess bilirubin from blood |
US20210346580A1 (en) * | 2020-05-11 | 2021-11-11 | Qisda Corporation | Hemodialyzer and hemodialysis system |
Family Cites Families (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3673612A (en) * | 1970-08-28 | 1972-07-04 | Massachusetts Inst Technology | Non-thrombogenic materials and methods for their preparation |
US3844989A (en) * | 1971-12-23 | 1974-10-29 | Toray Industries | Shampooer with rotary foam generating means anti-thrombogenic polymer compositions with internally bound heparin |
JPS565542B2 (es) * | 1973-05-31 | 1981-02-05 | ||
US4269712A (en) * | 1979-05-14 | 1981-05-26 | Cordis Dow Corp. | Hollow fiber separatory element and method of making same |
US4425234A (en) * | 1979-07-30 | 1984-01-10 | Hospal Ltd. | Hollow fiber separatory device |
JPS5714358A (en) * | 1980-07-02 | 1982-01-25 | Toray Industries | Antithrombus medical material |
DE3071275D1 (en) * | 1980-09-01 | 1986-01-16 | Teijin Ltd | Heparin derivative, its production and methods for imparting antithrombotic activity to biomedical materials |
JPS5778862A (en) * | 1980-11-04 | 1982-05-17 | Kogyo Gijutsuin | Blood pump having antithrombus property |
JPS585320A (ja) * | 1981-07-01 | 1983-01-12 | Toray Ind Inc | グラフト共重合体 |
US4529614A (en) * | 1981-12-02 | 1985-07-16 | Becton, Dickinson And Company | One step anticoagulant coating |
JPS6022901A (ja) * | 1983-07-05 | 1985-02-05 | Toray Ind Inc | 選択透過性中空繊維 |
SE444950B (sv) * | 1984-09-28 | 1986-05-20 | Ytkemiska Inst | Ytbelagd artikel, forfarande och medel for framstellning derav samt anvendning derav |
SE8501111L (sv) * | 1985-03-07 | 1986-03-03 | Gambro Dialysatoren | Sett att framstella en semipermeabel halfiber |
WO1986007541A1 (en) * | 1985-06-19 | 1986-12-31 | Yasushi Zyo | Composition which can impart antithrombotic ability and medical apparatus to be in contact with blood |
US4871357A (en) * | 1986-01-21 | 1989-10-03 | Baxter International Inc. | Ionic heparin coating |
JP2510540B2 (ja) * | 1986-11-19 | 1996-06-26 | 東レ株式会社 | ポリアクリロニトリル系半透膜及びその製造法 |
EP0273700B1 (en) * | 1986-12-25 | 1992-03-04 | Sumitomo Electric Industries Limited | Process for producing a medical vinyl chloride resin material |
JPS63220878A (ja) * | 1987-03-09 | 1988-09-14 | 住友ベークライト株式会社 | 抗凝血性医用成形体の製造方法 |
US4906465A (en) * | 1987-10-19 | 1990-03-06 | Massachusetts Institute Of Technology | Antithrombogenic devices containing polysiloxanes |
NL8800577A (nl) * | 1988-03-08 | 1989-10-02 | Stichting Tech Wetenschapp | Werkwijze voor het aanbrengen van een bloedcompatibele bekleding op polyetherurethaanvormstukken. |
US4888109A (en) * | 1988-11-17 | 1989-12-19 | Manohar Namala L | Hemofilter for use in a continuous arterio-venous hemofiltration |
-
1990
- 1990-04-25 EP EP90906364A patent/EP0423369B1/en not_active Expired - Lifetime
- 1990-04-25 DE DE69013457T patent/DE69013457T2/de not_active Expired - Fee Related
- 1990-04-25 ES ES90906364T patent/ES2061030T3/es not_active Expired - Lifetime
- 1990-04-25 WO PCT/JP1990/000536 patent/WO1990012607A1/ja active IP Right Grant
- 1990-04-25 US US07/623,458 patent/US5254249A/en not_active Expired - Lifetime
- 1990-04-25 KR KR1019900702662A patent/KR920700048A/ko not_active Application Discontinuation
- 1990-04-25 AT AT90906364T patent/ATE112967T1/de not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
DE69013457D1 (de) | 1994-11-24 |
KR920700048A (ko) | 1992-02-19 |
WO1990012607A1 (en) | 1990-11-01 |
DE69013457T2 (de) | 1995-02-23 |
EP0423369A1 (en) | 1991-04-24 |
US5254249A (en) | 1993-10-19 |
EP0423369B1 (en) | 1994-10-19 |
EP0423369A4 (en) | 1991-10-02 |
ATE112967T1 (de) | 1994-11-15 |
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Legal Events
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FG2A | Definitive protection |
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