ES2059411T3 - Agentes quelantes bifuncionales. - Google Patents

Agentes quelantes bifuncionales.

Info

Publication number
ES2059411T3
ES2059411T3 ES88101776T ES88101776T ES2059411T3 ES 2059411 T3 ES2059411 T3 ES 2059411T3 ES 88101776 T ES88101776 T ES 88101776T ES 88101776 T ES88101776 T ES 88101776T ES 2059411 T3 ES2059411 T3 ES 2059411T3
Authority
ES
Spain
Prior art keywords
chelating agents
bifunctional chelating
bifunctional
polyaminopolycarbonylate
carboxymethylate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES88101776T
Other languages
English (en)
Other versions
ES2059411T5 (es
Inventor
David K Johnson
Steven J Kline
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26686191&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2059411(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Application granted granted Critical
Publication of ES2059411T3 publication Critical patent/ES2059411T3/es
Publication of ES2059411T5 publication Critical patent/ES2059411T5/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C275/42—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by carboxyl groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C335/04—Derivatives of thiourea
    • C07C335/16—Derivatives of thiourea having nitrogen atoms of thiourea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C335/22—Derivatives of thiourea having nitrogen atoms of thiourea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by carboxyl groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

LA PRESENTE INVENCION PRESENTA AGENTES QUELANTES BIFUNCIONALES QUE COMPRENDEN UNAPORCION REACTIVA DE SUSTRATO UNICO INCORPORADA A UNA RAMA DE CARBOXIMETILO DE UNA ESTRUCTURA QUELANTE DE POLIAMINOPOLICARBOXILATO CAPAZ DE FORMAR COMPLEJOS ESTABLES CON IONES METALICOS.
ES88101776T 1987-02-13 1988-02-08 Agentes quelantes bifuncionales. Expired - Lifetime ES2059411T5 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1451787A 1987-02-13 1987-02-13
US07/136,180 US5057302A (en) 1987-02-13 1988-01-04 Bifunctional chelating agents

Publications (2)

Publication Number Publication Date
ES2059411T3 true ES2059411T3 (es) 1994-11-16
ES2059411T5 ES2059411T5 (es) 1997-03-16

Family

ID=26686191

Family Applications (1)

Application Number Title Priority Date Filing Date
ES88101776T Expired - Lifetime ES2059411T5 (es) 1987-02-13 1988-02-08 Agentes quelantes bifuncionales.

Country Status (6)

Country Link
US (1) US5057302A (es)
EP (1) EP0279307B2 (es)
JP (1) JPS63290854A (es)
AU (1) AU605241B2 (es)
DE (1) DE3884233T3 (es)
ES (1) ES2059411T5 (es)

Families Citing this family (97)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5567411A (en) * 1986-11-10 1996-10-22 State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of The University Of Oregon Dendritic amplifier molecules having multiple terminal active groups stemming from a benzyl core group
US4994560A (en) * 1987-06-24 1991-02-19 The Dow Chemical Company Functionalized polyamine chelants and radioactive rhodium complexes thereof for conjugation to antibodies
ATE107276T1 (de) * 1988-02-03 1994-07-15 Hybritech Inc Modifizierte haptene, nützlich als bildformendes agens und als arzneimittel.
US5756065A (en) * 1988-06-24 1998-05-26 The Dow Chemical Company Macrocyclic tetraazacyclododecane conjugates and their use as diagnostic and therapeutic agents
BR8907507A (pt) * 1988-06-24 1991-06-11 Dow Chemical Co Quelante bifuncional macrociclico,seus complexos e seus conjugados com anticorpos
PT90959B (pt) * 1988-06-24 1995-05-04 Dow Chemical Co Processo para a preparacao de quelantes macrociclicos bifuncionais, de seus complexos e seus conjugados com anticorpos
US5439665A (en) * 1988-07-29 1995-08-08 Immunomedics Detection and treatment of infectious and inflammatory lesions
US5066789A (en) * 1988-09-30 1991-11-19 Neorx Corporation Targeting substance-diagnostic/therapeutic agent conjugates having Schiff base linkages
WO1990003401A1 (en) * 1988-09-30 1990-04-05 Neorx Corporation Targeting substance-diagnostic/therapeutic agent conjugates having schiff base linkages
US6139603A (en) * 1989-02-22 2000-10-31 L'air Liquide, Societe Anonyme Pour L'etude Et L'exploitation Des Procedes Georges Claude Process for recovering oxygen
US5645818A (en) * 1989-03-24 1997-07-08 Guerbet S.A. Diagnostic compositions comprising a complex formed by a nitrogenous macrocyclic ligand with metal ions
US5914095A (en) * 1989-04-07 1999-06-22 Salutar, Inc. Polychelants containg amide bonds
US5292868A (en) * 1989-05-26 1994-03-08 Akzo N.V. Chelating agents for attaching metal ions to proteins
US5808003A (en) * 1989-05-26 1998-09-15 Perimmune Holdings, Inc. Polyaminocarboxylate chelators
US5334729A (en) * 1989-06-29 1994-08-02 Associated Universities, Inc. Stable radiometal antibody immunoconjugates
US5089663A (en) * 1989-06-29 1992-02-18 Associated Universities, Inc. Cyclohexyl-triethylenetetraamine hexacetic acid
US5695739A (en) * 1989-06-30 1997-12-09 Schering Aktiengesellschaft Derivatized DTPA complexes, pharmaceutical agents containing these compounds, their use, and processes for their production
US6039931A (en) * 1989-06-30 2000-03-21 Schering Aktiengesellschaft Derivatized DTPA complexes, pharmaceutical agents containing these compounds, their use, and processes for their production
US5244816A (en) * 1989-10-11 1993-09-14 Akzo N.V. Method for purifying chelator conjugated compounds
DE3938992A1 (de) 1989-11-21 1991-05-23 Schering Ag Kaskadenpolymer-gebundene komplexbildner, deren komplexe und konjugate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mittel
US5091542A (en) * 1990-03-09 1992-02-25 Hybritech Incorporated Tris-maleimido compounds as intermediates in trifunctional antibody synthesis
US5124471A (en) * 1990-03-26 1992-06-23 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Bifunctional dtpa-type ligand
US5645815A (en) 1991-02-08 1997-07-08 Diatide, Inc. Radiolabled compounds for thrombus imaging
DE69219924T2 (de) * 1991-03-01 1998-01-02 Uyemura & Co C Analyse von Zinn, Blei oder Zinn-Blei-Legierung enthaltende Plattierungslösungen
US5310539A (en) * 1991-04-15 1994-05-10 Board Of Regents, The University Of Texas System Melanin-based agents for image enhancement
JP2901787B2 (ja) * 1991-07-15 1999-06-07 日本メジフィジックス株式会社 核磁気共鳴造影剤
US5378807A (en) * 1991-08-08 1995-01-03 University Of Massachusetts At Lowell γ-poly(glutamic acid) esters
US5562894A (en) * 1991-08-09 1996-10-08 Regents Of The University Of California Amino-acyl-type and catecholamine-type contrast agents for MRI
EP0662001A4 (en) * 1991-11-08 1995-11-22 Univ Missouri Multifunctional ligands for potential use in the design of therapeutic or diagnostic radiopharmaceutical imaging agents.
US5310535A (en) * 1992-04-24 1994-05-10 The Dow Chemical Company Carboxamide modified polyamine chelators and radioactive complexes thereof for conjugation to antibodies
US5505931A (en) * 1993-03-04 1996-04-09 The Dow Chemical Company Acid cleavable compounds, their preparation and use as bifunctional acid-labile crosslinking agents
AU2404192A (en) * 1992-08-04 1994-03-03 State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of The University Of Oregon, The Amplifier molecules for enhancement of diagnosis and therapy
DE69327659T2 (de) * 1992-10-14 2000-09-21 Nycomed Imaging As Therapeutische und diagnostische bilderzeugungzusammensetzung und verfahren zur herstellung
EP0664819B1 (en) * 1992-10-14 1997-08-06 Nycomed Imaging As Chelating polymers
US5817292A (en) * 1992-10-14 1998-10-06 Nycomed Imaging As MR imaging compositions and methods
US5330743A (en) * 1992-11-12 1994-07-19 Magnetic Research, Inc. Aminosaccharide contrast agents for magnetic resonance images
US5466439A (en) * 1992-11-12 1995-11-14 Magnetic Research, Inc. Polymeric contrast enhancing agents for magnetic resonance images
US5650134A (en) * 1993-01-12 1997-07-22 Novartis Ag (Formerly Sandoz Ltd.) Peptides
US5578564A (en) * 1993-07-23 1996-11-26 Somatogen, Inc. Nickel-free hemoglobin and methods for producing such hemoglobin
IT1269839B (it) * 1994-05-26 1997-04-15 Bracco Spa Coniugati di acidi biliari, loro derivati con complessi metallici e relativi usi
IL114235A0 (en) * 1994-07-14 1995-10-31 Schering Ag Oligonucleotide conjugates and processes for noninvasive diagnosis utilizing the same
IL114237A (en) * 1994-07-14 2000-08-31 Schering Ag Oligonucleotide conjugates and diagnostic processes utilizing the same
US5539138A (en) * 1994-07-28 1996-07-23 Merck Frosst Canada, Inc. High affinity chelates containing isothiocyanate groups, useful for coupling with peptides and proteins
US5672335A (en) * 1994-11-30 1997-09-30 Schering Aktiengesellschaft Use of metal complexes as liver and gallbladder X-ray diagnostic agents
US5886143A (en) * 1994-12-07 1999-03-23 Neorx Corporation Hepatic-directed compounds and reagents for preparation thereof
US5641623A (en) * 1995-01-04 1997-06-24 Martin; Mark T. Electrochemiluminescence assay
US5643713A (en) * 1995-06-07 1997-07-01 Liang; Pam Electrochemiluminescent monitoring of compounds
TW319763B (es) 1995-02-01 1997-11-11 Epix Medical Inc
US5573747A (en) * 1995-05-19 1996-11-12 Lacy; Jeffrey L. Method for preparing a physiological isotonic pet radiopharmaceutical of 62 Cu
US6136311A (en) * 1996-05-06 2000-10-24 Cornell Research Foundation, Inc. Treatment and diagnosis of cancer
US6107090A (en) 1996-05-06 2000-08-22 Cornell Research Foundation, Inc. Treatment and diagnosis of prostate cancer with antibodies to extracellur PSMA domains
US6458337B1 (en) 1996-08-02 2002-10-01 Dibra S.P.A Diagnostic imaging contrast agent with improved in serum relaxivity
US6403055B1 (en) 1996-08-02 2002-06-11 Dibra S.P.A. Diagnostic imaging contrast agent with improved in serum relaxivity
IT1290417B1 (it) * 1996-08-02 1998-12-03 Bracco Spa Composti chelanti derivati di acidi poliamminopolicarbossilici, loro chelati con ioni metallici paramagnetici, loro preparazione ed
EP1052985B1 (en) 1998-02-04 2004-12-22 University Of Florida Research Foundation, Inc. N,n'-bis(2-hydroxybenzyl)ethylenediamine-n,n'-diacetic acid and sodium salts thereof for iron chelating therapy
IT1298613B1 (it) * 1998-03-10 2000-01-12 Bracco Spa Chelati complessi di manganese ad alta relassivita' in siero
IT1298614B1 (it) * 1998-03-10 2000-01-12 Bracco Spa Chelati complessi di manganese ad alta relassivita' in siero
US6703050B1 (en) * 1998-09-04 2004-03-09 The Regents Of The University Of Michigan Methods and compositions for the prevention or treatment of cancer
IT1304501B1 (it) * 1998-12-23 2001-03-19 Bracco Spa Uso di derivati di acidi biliari coniugati con complessi metallicicome "blood pool agents" per l'indagine diagnostica tramite risonanza
US6767741B1 (en) * 1999-08-27 2004-07-27 Invitrogen Corporation Metal binding compounds and their use in cell culture medium compositions
EP1229934B1 (en) 1999-10-01 2014-03-05 Immunogen, Inc. Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents
AU2293101A (en) 1999-12-21 2001-07-03 Geltex Pharmaceuticals, Inc. Method for making hbed
WO2001052900A2 (en) * 2000-01-21 2001-07-26 Mallinckrodt Inc. Novel orthogonally protected amino acid chelators for biomedical applications
IT1317862B1 (it) * 2000-02-29 2003-07-15 Bracco Spa Coniugati di acidi biliari con chelati complessi di ioni metallici eloro uso.
US7354721B2 (en) * 2000-09-22 2008-04-08 Clontech Laboratories, Inc. Highly sensitive proteomic analysis methods, and kits and systems for practicing the same
US20030007974A1 (en) * 2001-05-30 2003-01-09 Nanus David M. Endopeptidase/anti-PSMA antibody fusion proteins for treatment of cancer
ATE535258T1 (de) * 2001-06-01 2011-12-15 Cornell Res Foundation Inc Modifizierte antikörper gegen prostata- spezifisches membranantigen und ihre verwendungen
US7514078B2 (en) * 2001-06-01 2009-04-07 Cornell Research Foundation, Inc. Methods of treating prostate cancer with anti-prostate specific membrane antigen antibodies
US7666414B2 (en) * 2001-06-01 2010-02-23 Cornell Research Foundation, Inc. Methods for treating prostate cancer using modified antibodies to prostate-specific membrane antigen
JP2004534808A (ja) * 2001-06-22 2004-11-18 シエーリング アクチエンゲゼルシャフト （エチレン）−（プロピレン）−トリアミン五酢酸誘導体類、それらの製造方法、及び医薬剤の製造のためへのそれらの使用
EP1427377A4 (en) * 2001-09-20 2006-04-12 Cornell Res Foundation Inc METHOD AND COMPOSITIONS FOR TREATING OR PREVENTING SKIN DISEASES USING BINDERS SPECIFIC TO THE PROSTATE-SPECIFIC MEMBRANEANT
US20070248689A1 (en) * 2002-05-24 2007-10-25 Regents Of The University Of Michigan Copper lowering treatment of inflammatory and fibrotic diseases
US6855340B2 (en) * 2002-05-24 2005-02-15 Regents Of The University Of Michigan Copper lowering treatment of inflammatory and fibrotic diseases
GEP20074270B (en) 2002-07-23 2007-12-25 Univ Michigan Tetrapropylammonium tetrathiomolybdate and related compounds for anti-angiogenic therapies
US20040136998A1 (en) * 2002-10-30 2004-07-15 Bander Neil H. Methods and compositions for treating or preventing insulin-related disorders using binding agents specific for prostate specific membrane antigen
US7582308B2 (en) 2002-12-23 2009-09-01 Kimberly-Clark Worldwide, Inc. Odor control composition
WO2004063701A2 (en) * 2003-01-10 2004-07-29 Millennium Pharmaceuticals, Inc. Methods of diagnosing and treating cancer
US7141518B2 (en) 2003-10-16 2006-11-28 Kimberly-Clark Worldwide, Inc. Durable charged particle coatings and materials
US7582485B2 (en) 2003-10-16 2009-09-01 Kimberly-Clark Worldride, Inc. Method and device for detecting ammonia odors and helicobacter pylori urease infection
US7837663B2 (en) 2003-10-16 2010-11-23 Kimberly-Clark Worldwide, Inc. Odor controlling article including a visual indicating device for monitoring odor absorption
US7678367B2 (en) 2003-10-16 2010-03-16 Kimberly-Clark Worldwide, Inc. Method for reducing odor using metal-modified particles
US7413550B2 (en) 2003-10-16 2008-08-19 Kimberly-Clark Worldwide, Inc. Visual indicating device for bad breath
US7879350B2 (en) 2003-10-16 2011-02-01 Kimberly-Clark Worldwide, Inc. Method for reducing odor using colloidal nanoparticles
US7754197B2 (en) 2003-10-16 2010-07-13 Kimberly-Clark Worldwide, Inc. Method for reducing odor using coordinated polydentate compounds
US7438875B2 (en) 2003-10-16 2008-10-21 Kimberly-Clark Worldwide, Inc. Method for reducing odor using metal-modified silica particles
US7794737B2 (en) 2003-10-16 2010-09-14 Kimberly-Clark Worldwide, Inc. Odor absorbing extrudates
US7488520B2 (en) 2003-10-16 2009-02-10 Kimberly-Clark Worldwide, Inc. High surface area material blends for odor reduction, articles utilizing such blends and methods of using same
US7259249B2 (en) 2003-12-01 2007-08-21 Immunomedics, Inc. Method for preparing conjugates of proteins and chelating agents
US20050202020A1 (en) * 2004-01-09 2005-09-15 Jeffrey Ross Diagnosing and treating cancer
WO2005094882A1 (en) * 2004-03-03 2005-10-13 Millennium Pharmaceuticals, Inc. Modified antibodies to prostate-specific membrane antigen and uses thereof
US8445431B2 (en) * 2004-06-01 2013-05-21 The Ohio State University Ligands having metal binding ability and targeting properties
US20070025910A1 (en) 2005-07-29 2007-02-01 Norenberg Jeffrey P Anticancer therapy
EP2024117B1 (en) 2006-04-24 2012-11-14 Nm Tech Ltd. Nanomaterials And Microdevices Technology Functional nanomaterials with antibacterial and antiviral activity
US8859492B2 (en) 2011-05-12 2014-10-14 MetalloPharm, LLC Metallodrugs having improved pharmacological properties, and methods of manufacture and use thereof
WO2013109927A2 (en) 2012-01-18 2013-07-25 Metallopharm Llc Metallodrugs having improved pharmacological properties and methods of manufacture and use thereof
US10125385B2 (en) * 2013-02-25 2018-11-13 Pdl Biopharma, Inc. Electrochemiluminescence (ECL) detection reagents and related methods for measuring enzyme activity
EP3746535A1 (en) 2018-01-30 2020-12-09 Eastman Chemical Company Compositions comprising aminocarboxylate chelating agents

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3994966A (en) * 1972-09-28 1976-11-30 The Board Of Trustees Of The Leland Stanford Junior University Chelating agents
US4647447A (en) * 1981-07-24 1987-03-03 Schering Aktiengesellschaft Diagnostic media
GB2109407B (en) * 1981-10-27 1985-12-18 Hybritech Inc Tumour imaging with radiolabelled monoclonal antibodies
CA1203164A (en) * 1982-03-09 1986-04-15 Thomas J. Mckearn Antibody conjugates
US4454106A (en) * 1982-06-07 1984-06-12 Gansow Otto A Use of metal chelate conjugated monoclonal antibodies
CA1223831A (en) * 1982-06-23 1987-07-07 Dean Engelhardt Modified nucleotides, methods of preparing and utilizing and compositions containing the same
DE3324235A1 (de) * 1983-07-01 1985-01-10 Schering AG, 1000 Berlin und 4709 Bergkamen Neue komplexbildner, komplexe und komplexsalze
CA1260827A (en) * 1984-08-31 1989-09-26 Richard C. Siegel Antibody-metal ion complexes
US4837003A (en) * 1984-09-13 1989-06-06 Mallinckrodt, Inc. Radiolabeled antibody fragments
US4826673A (en) * 1985-01-09 1989-05-02 Mallinckrodt, Inc. Methods and compositions for enhancing magnetic resonance imaging
US4678667A (en) * 1985-07-02 1987-07-07 501 Regents of the University of California Macrocyclic bifunctional chelating agents
US4885363A (en) * 1987-04-24 1989-12-05 E. R. Squibb & Sons, Inc. 1-substituted-1,4,7-triscarboxymethyl-1,4,7,10-tetraazacyclododecane and analogs
IT1213029B (it) * 1986-01-30 1989-12-07 Bracco Ind Chimica Spa Chelati di ioni metallici paramagnetici.
CA1304886C (en) * 1986-07-10 1992-07-07 Heinz Dobeli Metal chelate resins
US4831175A (en) * 1986-09-05 1989-05-16 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Backbone polysubstituted chelates for forming a metal chelate-protein conjugate

Also Published As

Publication number Publication date
EP0279307A3 (en) 1990-05-09
EP0279307B2 (en) 1996-11-13
DE3884233D1 (de) 1993-10-28
EP0279307A2 (en) 1988-08-24
DE3884233T3 (de) 1997-06-05
EP0279307B1 (en) 1993-09-22
AU605241B2 (en) 1991-01-10
JPS63290854A (ja) 1988-11-28
AU1168588A (en) 1988-08-18
ES2059411T5 (es) 1997-03-16
DE3884233T2 (de) 1994-03-03
US5057302A (en) 1991-10-15

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