AU2293101A - Method for making hbed - Google Patents

Method for making hbed

Info

Publication number
AU2293101A
AU2293101A AU22931/01A AU2293101A AU2293101A AU 2293101 A AU2293101 A AU 2293101A AU 22931/01 A AU22931/01 A AU 22931/01A AU 2293101 A AU2293101 A AU 2293101A AU 2293101 A AU2293101 A AU 2293101A
Authority
AU
Australia
Prior art keywords
hbed
making
making hbed
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU22931/01A
Inventor
James M. Mckearin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Geltex Pharmaceuticals Inc
Original Assignee
Geltex Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Geltex Pharmaceuticals Inc filed Critical Geltex Pharmaceuticals Inc
Publication of AU2293101A publication Critical patent/AU2293101A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C251/02—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups
    • C07C251/24—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups having carbon atoms of imino groups bound to carbon atoms of six-membered aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/46—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C215/48—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by hydroxy groups
    • C07C215/50—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by hydroxy groups with amino groups and the six-membered aromatic ring, or the condensed ring system containing that ring, bound to the same carbon atom of the carbon chain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/02—Formation of carboxyl groups in compounds containing amino groups, e.g. by oxidation of amino alcohols
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
    • C07C227/18—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
AU22931/01A 1999-12-21 2000-12-21 Method for making hbed Abandoned AU2293101A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US17167399P 1999-12-21 1999-12-21
US60171673 1999-12-21
PCT/US2000/035321 WO2001046114A1 (en) 1999-12-21 2000-12-21 Method for making hbed

Publications (1)

Publication Number Publication Date
AU2293101A true AU2293101A (en) 2001-07-03

Family

ID=22624703

Family Applications (2)

Application Number Title Priority Date Filing Date
AU22931/01A Abandoned AU2293101A (en) 1999-12-21 2000-12-21 Method for making hbed
AU24562/01A Abandoned AU2456201A (en) 1999-12-21 2000-12-21 N,n'-bis(2-hydroxybenzyl)ethylenediamine-n,n'-diacetic acid in iron chelating therapy

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU24562/01A Abandoned AU2456201A (en) 1999-12-21 2000-12-21 N,n'-bis(2-hydroxybenzyl)ethylenediamine-n,n'-diacetic acid in iron chelating therapy

Country Status (5)

Country Link
US (2) US6646157B2 (en)
EP (1) EP1246618A1 (en)
AU (2) AU2293101A (en)
CA (1) CA2394524A1 (en)
WO (2) WO2001046114A1 (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7160855B2 (en) * 2002-03-14 2007-01-09 Children's Hospital & Research Center At Oakland Enhancement of iron chelation therapy
JP2009531379A (en) * 2006-03-29 2009-09-03 ビーエーエスエフ ソシエタス・ヨーロピア Use of strobilurin to treat iron metabolism dysfunction
ES2551880T3 (en) * 2007-09-20 2015-11-24 Przedsiebiorstwo Produkcyjno-Consultingowe Adob Sp. Z O.O. Sp. K. A process for the preparation of N, N'-bis (2-hydroxybenzyl) ethylenediamine-N, N'-diacetic acid and its derivatives
IT1396903B1 (en) * 2009-03-23 2012-12-20 River Pharma Srl COMPOSITIONS INCLUDING ANTIOXIDANTS AND CHELANTS OF THE IRON AND THEIR USE FOR THE TREATMENT OF THE IRON OVERLOAD
US8378134B2 (en) * 2009-09-30 2013-02-19 General Electric Company Hydroxylated contrast enhancement agents
US20110077417A1 (en) * 2009-09-30 2011-03-31 General Electric Company Intermediates for Hydroxylated Contrast Enhancement Agents
US20110077396A1 (en) * 2009-09-30 2011-03-31 General Electric Company Intermediates for hydroxylated contrast enhancement agents
TR201909965T4 (en) * 2015-06-25 2019-07-22 Akzo Nobel Chemicals Int Bv Process of preparing phenolic ethylenediamine diacetic acid compounds.
ES2746868T3 (en) * 2015-06-25 2020-03-09 Nouryon Chemicals Int Bv Process for preparing phenolic compounds of diacetic ethylenediamine acid
CN109438267B (en) * 2018-11-29 2021-06-01 首都医科大学 Bifunctional complexing agent containing tetraphenylethylene and preparation method and application thereof
CN110041267A (en) * 2019-05-29 2019-07-23 宁夏蓝丰精细化工有限公司 Carbendazim clean-production system
ES2944701T3 (en) 2020-12-01 2023-06-23 Przed Produkcyjno Consultingowe Adob Sp Z O O A process for the preparation of salts of N,N'-disubstituted ethylenediamine-N,N'-diacetic acid derivatives and their use

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3005848A (en) 1957-09-09 1961-10-24 Geigy Chem Corp Ethylenediamine derivatives containing aromatic rings
US3758540A (en) 1968-02-13 1973-09-11 A Martell Ferric chelates of n-(2-hydroxybenzyl) substituted aminopoly carboxylic acids
BE786946A (en) 1971-07-29 1973-01-29 Ciba Geigy CHELATES TO COMBAT SYMPTOMS OF METAL DEFICIENCY IN BIOLOGICAL SYSTEMS
GB1439048A (en) 1973-09-11 1976-06-09 Ciba Geigy Ag Metal complexes of bis-azomethines and processes for their manufacture
FR2267308B1 (en) 1974-04-12 1976-10-08 Protex Manuf Prod Chimiq
CH602857A5 (en) 1976-12-10 1978-08-15 Ciba Geigy Ag
US4130582A (en) 1977-04-19 1978-12-19 Ciba-Geigy Corporation Preparation of phenolic ethylenediaminepolycarboxylic acids
US4352751A (en) 1979-09-10 1982-10-05 Analytical Radiation Corporation Species-linked diamine triacetic acids and their chelates
US4528196A (en) 1981-02-23 1985-07-09 The United States Of America As Represented By The Department Of Health And Human Services Chelating agents for the treatment of iron overload
US4647447A (en) 1981-07-24 1987-03-03 Schering Aktiengesellschaft Diagnostic media
US4454106A (en) 1982-06-07 1984-06-12 Gansow Otto A Use of metal chelate conjugated monoclonal antibodies
US4909257A (en) 1986-05-01 1990-03-20 The Regents Of The University Of California Method for attaining in vivo tissue-specific contrast by nuclear magnetic resonance imaging
US5057302A (en) 1987-02-13 1991-10-15 Abbott Laboratories Bifunctional chelating agents
US5227474A (en) 1987-02-13 1993-07-13 Abbott Laboratories Bifunctional chelating agents
IE980697A1 (en) * 1988-10-31 2000-12-13 Dow Chemical Co Chelants possessing ortho ligating functionality and complexes thereof
US5376154A (en) * 1991-05-13 1994-12-27 The Lubrizol Corporation Low-sulfur diesel fuels containing organometallic complexes
US5840739A (en) 1992-11-16 1998-11-24 University Of Florida Research Foundation, Inc. Thiazoline acid derivatives
US5534241A (en) 1993-07-23 1996-07-09 Torchilin; Vladimir P. Amphipathic polychelating compounds and methods of use
AU1033495A (en) 1993-12-16 1995-07-03 Ciba-Geigy Ag N,n'-bis(2-hydroxybenzyl)ethylenediamine-n,n'-diacetic acid derivatives as chelating agents
US5539138A (en) 1994-07-28 1996-07-23 Merck Frosst Canada, Inc. High affinity chelates containing isothiocyanate groups, useful for coupling with peptides and proteins
AU2958397A (en) * 1996-05-21 1997-12-09 Novartis Ag N,n'-di(2-hydroxybenzyl)ethylenediamine-n,n'-diacetic acid derivatives
TR200002256T2 (en) * 1998-02-04 2001-03-21 University Of Florida Research Foundation, Inc. Pharmaceuticals containing N, N '-BIS (2-Hydroxybenzyl) ethylenediamine-N, N'diacetic acid in the treatment of iron chelating.

Also Published As

Publication number Publication date
CA2394524A1 (en) 2001-06-28
WO2001045696A1 (en) 2001-06-28
EP1246618A1 (en) 2002-10-09
US6646157B2 (en) 2003-11-11
WO2001046114A1 (en) 2001-06-28
US20010047108A1 (en) 2001-11-29
AU2456201A (en) 2001-07-03
US20010039295A1 (en) 2001-11-08

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase