ES2056813T3 - Preparacion de derivados del acido piperidinilciclopentilheptenoico. - Google Patents

Preparacion de derivados del acido piperidinilciclopentilheptenoico.

Info

Publication number
ES2056813T3
ES2056813T3 ES87300673T ES87300673T ES2056813T3 ES 2056813 T3 ES2056813 T3 ES 2056813T3 ES 87300673 T ES87300673 T ES 87300673T ES 87300673 T ES87300673 T ES 87300673T ES 2056813 T3 ES2056813 T3 ES 2056813T3
Authority
ES
Spain
Prior art keywords
sub
ions
preparation
formula
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES87300673T
Other languages
English (en)
Inventor
Roger Barrett
Clive Alwin Meerholz
Brian David Judkins
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Application granted granted Critical
Publication of ES2056813T3 publication Critical patent/ES2056813T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/155Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

SE DESCRIBE UN PROCEDIMIENTO PARA LA PREPARACION DE UN COMPUESTO DE FORMULA (2) (EN LA QUE R ES UN GRUPO ALQUILO DE 1 A 6 CARBONOS O UN GRUPO ARALQUILO DE 7 A 20 CARBONOS) Y SUS SALES, QUE COMPRENDE REDUCIR UN COMPUESTO DE FORMULA (3) ( O UNA SAL DEL MISMO), UTILIZANDO UN SISTEMA REDUCTOR QUE COMPRENDE IONES BOROHIDRURO E IONES METALICOS SELECCIONADOS DE ENTRE IONES LANTANIDOS, IONES DE METALES ALCALINOTERREOS E IONES DE ITRIO EN SOLUCION.EL SISTEMA REDUCTOR PUEDE SER PROPORCIONADO POR UN BOROHIDRURO (POR EJEMPLO, NABH4) Y UNA SAL METALICA (POR EJEMPLO, CECL3). SEGUIDAMENTE, SI SE DESEA, PUEDE HIDROLIZARSE EL ESTER (2) PARA DAR EL ACIDO DE PROCEDENCIA. EL ESTER DE FORMULA (3), EN LA QUE R ES UN GRUPO METILO, ES UN COMPUESTO NUEVO.
ES87300673T 1986-01-28 1987-01-27 Preparacion de derivados del acido piperidinilciclopentilheptenoico. Expired - Lifetime ES2056813T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB868601985A GB8601985D0 (en) 1986-01-28 1986-01-28 Chemical process

Publications (1)

Publication Number Publication Date
ES2056813T3 true ES2056813T3 (es) 1994-10-16

Family

ID=10592036

Family Applications (1)

Application Number Title Priority Date Filing Date
ES87300673T Expired - Lifetime ES2056813T3 (es) 1986-01-28 1987-01-27 Preparacion de derivados del acido piperidinilciclopentilheptenoico.

Country Status (18)

Country Link
US (1) US4835278A (es)
EP (1) EP0234737B1 (es)
JP (1) JPH0759573B2 (es)
KR (1) KR940007303B1 (es)
AT (1) ATE109140T1 (es)
AU (1) AU596822B2 (es)
CA (1) CA1292471C (es)
DE (1) DE3750267T2 (es)
DK (1) DK42587A (es)
ES (1) ES2056813T3 (es)
FI (1) FI87563C (es)
GB (1) GB8601985D0 (es)
HU (1) HU198462B (es)
IE (1) IE63943B1 (es)
NO (1) NO170279C (es)
PL (1) PL150767B1 (es)
PT (1) PT84195B (es)
ZA (1) ZA87586B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8715333D0 (en) * 1987-06-30 1987-08-05 Glaxo Group Ltd Process
US5221695A (en) * 1987-12-22 1993-06-22 Glaxo Group Limited Aqueous formulation containing a piperidinylcyclopentylheptenoic acid derivative and beta-cyclodextrin
JPH01115583U (es) * 1988-01-29 1989-08-03
GB8814725D0 (en) * 1988-06-21 1988-07-27 Glaxo Group Ltd Medicaments
SE465882B (sv) * 1990-03-15 1991-11-11 Uponor Nv Anordning vid avlopp innefattande sedimenteringskammare, vaetskekammare och haevert

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2927855A1 (de) * 1978-07-11 1980-03-20 Glaxo Group Ltd Prostanoid-verbindungen
JPS5718671A (en) * 1980-04-30 1982-01-30 Glaxo Group Ltd Aminocyclopentane alkenoic acid and esters thereof,manufacture and drug composition
CA1191134A (en) * 1981-04-29 1985-07-30 Eric W. Collington Aminocyclopentanol acids and esters and their preparation and pharmaceutical formulation
JPS57183772A (en) * 1981-04-29 1982-11-12 Glaxo Group Ltd Aminocyclopentanol acids and esters, manufacture and medicinal composition
IL67041A (en) * 1981-10-29 1988-03-31 Glaxo Group Ltd 2-aminocyclopentane alkanoic and alkenoic acid esters,process for their preparation and pharmaceutical compositions containing them
GB2127406B (en) * 1982-09-16 1986-03-05 Glaxo Group Ltd Piperidinlycyclopentanolheptenoic acid salt
AT387220B (de) * 1982-10-28 1988-12-27 Glaxo Group Ltd Verfahren zur herstellung von aminocyclopentansaeuren

Also Published As

Publication number Publication date
FI870350A0 (fi) 1987-01-27
DK42587A (da) 1987-07-29
NO170279C (no) 1992-09-30
DK42587D0 (da) 1987-01-27
IE63943B1 (en) 1995-06-28
US4835278A (en) 1989-05-30
FI870350A (fi) 1987-07-29
FI87563B (fi) 1992-10-15
EP0234737A1 (en) 1987-09-02
EP0234737B1 (en) 1994-07-27
ZA87586B (en) 1987-09-30
DE3750267T2 (de) 1994-12-01
HU198462B (en) 1989-10-30
FI87563C (fi) 1993-01-25
ATE109140T1 (de) 1994-08-15
NO170279B (no) 1992-06-22
JPH0759573B2 (ja) 1995-06-28
GB8601985D0 (en) 1986-03-05
IE870205L (en) 1987-07-28
DE3750267D1 (de) 1994-09-01
HUT44526A (en) 1988-03-28
KR940007303B1 (ko) 1994-08-12
JPS62185072A (ja) 1987-08-13
NO870336L (no) 1987-07-29
PT84195B (pt) 1989-03-30
AU596822B2 (en) 1990-05-17
PL150767B1 (en) 1990-06-30
NO870336D0 (no) 1987-01-27
PT84195A (en) 1987-02-01
KR870007135A (ko) 1987-08-17
AU6807587A (en) 1987-07-30
PL263838A1 (en) 1988-07-07
CA1292471C (en) 1991-11-26

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