ES2055845T3 - Composicion farmaceutica para el tratamiento de la osteoporosis. - Google Patents
Composicion farmaceutica para el tratamiento de la osteoporosis.Info
- Publication number
- ES2055845T3 ES2055845T3 ES90120567T ES90120567T ES2055845T3 ES 2055845 T3 ES2055845 T3 ES 2055845T3 ES 90120567 T ES90120567 T ES 90120567T ES 90120567 T ES90120567 T ES 90120567T ES 2055845 T3 ES2055845 T3 ES 2055845T3
- Authority
- ES
- Spain
- Prior art keywords
- treatment
- pharmaceutical composition
- osteoporosis
- estrogen
- thyroid hormone
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 208000001132 Osteoporosis Diseases 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 229940011871 estrogen Drugs 0.000 abstract 3
- 239000000262 estrogen Substances 0.000 abstract 3
- AUYYCJSJGJYCDS-LBPRGKRZSA-N Thyrolar Chemical class IC1=CC(C[C@H](N)C(O)=O)=CC(I)=C1OC1=CC=C(O)C(I)=C1 AUYYCJSJGJYCDS-LBPRGKRZSA-N 0.000 abstract 2
- 239000005495 thyroid hormone Substances 0.000 abstract 2
- 229940036555 thyroid hormone Drugs 0.000 abstract 2
- 210000000988 bone and bone Anatomy 0.000 abstract 1
- 239000004615 ingredient Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/24—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Endocrinology (AREA)
- Physical Education & Sports Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Zoology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Reproductive Health (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
UN COMPUESTO FARMACEUTICO PARA EL TRATAMIENTO DE OSTEOPOROSIS, COMPRENDE UN ESTREGENO Y UNA HORMONA DE TIROIDE COMO INGREDIENTES EFECTIVOS. UTILIZANDO EL ESTROGENO CON COMBINACION CON LA HORMONA DE TIROIDE, SE PUEDE OBTENER UNA ACTIVIDAD MUCHISIMO MAS GRANDE EN INCREMENTAR LA CANTIDAD DE HUESO QUE EN EL CASO DE SUMINISTRAR SOLAMENTE EL ESTROGENO.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP28114189 | 1989-10-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2055845T3 true ES2055845T3 (es) | 1994-09-01 |
Family
ID=17634937
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES90120567T Expired - Lifetime ES2055845T3 (es) | 1989-10-26 | 1990-10-26 | Composicion farmaceutica para el tratamiento de la osteoporosis. |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US5116828A (es) |
| EP (1) | EP0424954B1 (es) |
| JP (1) | JP3113269B2 (es) |
| AT (1) | ATE104854T1 (es) |
| DE (1) | DE69008476T2 (es) |
| ES (1) | ES2055845T3 (es) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2123666T3 (es) * | 1992-03-21 | 1999-01-16 | Entec | Aplicacion de estriol para la preparacion de un sistema terapeutico transdermico para tratar la osteoporosis climaterica. |
| CA2152163A1 (en) * | 1992-12-29 | 1994-07-07 | Michael F. Holick | Use of vitamin d glycosides for the treatment or prevention of osteoporosis |
| US5776923A (en) * | 1993-01-19 | 1998-07-07 | Endorecherche, Inc. | Method of treating or preventing osteoporosis by adminstering dehydropiandrosterone |
| IL108371A (en) * | 1993-01-19 | 2009-09-01 | Endorech Inc | Use of sex steroid precursors to prepare medicaments for treatment of vaginal atrophy |
| US20030170290A1 (en) * | 1993-06-16 | 2003-09-11 | Shug Austin L. | Delayed release carnitine |
| JPH09100293A (ja) * | 1995-10-03 | 1997-04-15 | Kanebo Ltd | インターロイキン8の作用増強剤 |
| US6236946B1 (en) | 1995-12-13 | 2001-05-22 | Thomas S. Scanlan | Nuclear receptor ligands and ligand binding domains |
| US6266622B1 (en) * | 1995-12-13 | 2001-07-24 | Regents Of The University Of California | Nuclear receptor ligands and ligand binding domains |
| US6197291B1 (en) | 1996-06-27 | 2001-03-06 | Kanebo Limited | Agent for potentiating the effect of interleukin-8 |
| IT1292129B1 (it) * | 1997-06-11 | 1999-01-25 | Sunnimex Ltd | Medicamento utile per ridurre la massa grassa ed aumentare la massa magra nella donna in menopausa ed in entrambi i sessi nella |
| WO1999007381A1 (en) * | 1997-08-11 | 1999-02-18 | Weider Nutrition International, Inc. | Compositions and treatments to reduce side effects of administration of androgenic testosterone precursors |
| US6342611B1 (en) * | 1997-10-10 | 2002-01-29 | Cytovia, Inc. | Fluorogenic or fluorescent reporter molecules and their applications for whole-cell fluorescence screening assays for capsases and other enzymes and the use thereof |
| ID27922A (id) | 1998-06-11 | 2001-05-03 | Endorech Inc | KOMPOSISI FARMASETIKAL DAN PENGGUNAAN DARI ANDROST-5-ENA-3β, 17β-DIOL |
| US6667299B1 (en) * | 2000-03-16 | 2003-12-23 | Hollis-Eden Pharmaceuticals, Inc. | Pharmaceutical compositions and treatment methods |
| DE10027887A1 (de) * | 2000-05-31 | 2001-12-13 | Jenapharm Gmbh | Verbindungen mit einer Sulfonamidgruppe und diese Verbindungen enthaltende pharmazeutische Zusammensetzungen |
| US6503894B1 (en) | 2000-08-30 | 2003-01-07 | Unimed Pharmaceuticals, Inc. | Pharmaceutical composition and method for treating hypogonadism |
| US20040002482A1 (en) * | 2000-08-30 | 2004-01-01 | Dudley Robert E. | Androgen pharmaceutical composition and method for treating depression |
| US20040092494A9 (en) * | 2000-08-30 | 2004-05-13 | Dudley Robert E. | Method of increasing testosterone and related steroid concentrations in women |
| ITMI20110713A1 (it) | 2011-04-29 | 2012-10-30 | Bracco Imaging Spa | Processo per la preparazione di un derivato solfatato di3,5-diiodo-o-[3-iodofenil]-l-tirosina |
| ITMI20022394A1 (it) | 2002-11-13 | 2004-05-14 | Bracco Spa | Uso di triiodotironina 3-solfato come farmaco ad attivita' tireomimetica e relative formulazioni farmaceutiche. |
| US7829552B2 (en) * | 2003-11-19 | 2010-11-09 | Metabasis Therapeutics, Inc. | Phosphorus-containing thyromimetics |
| DE102004025985A1 (de) * | 2004-05-21 | 2005-12-15 | Schering Ag | Estriol- und Estetrol-Prodrugs |
| US7534780B2 (en) * | 2004-05-21 | 2009-05-19 | Bayer Schering Pharma Aktiengesellschaft | Estradiol prodrugs |
| US20050277625A1 (en) * | 2004-05-21 | 2005-12-15 | Ralf Wyrwa | Estriol and estetrol prodrugs |
| US20070088012A1 (en) * | 2005-04-08 | 2007-04-19 | Woun Seo | Method of treating or preventing type-2 diabetes |
| JP2008542301A (ja) | 2005-05-26 | 2008-11-27 | メタバシス・セラピューティクス・インコーポレイテッド | 脂肪性肝疾患の処置のための甲状腺ホルモン様薬剤 |
| MX2007014501A (es) * | 2005-05-26 | 2008-02-07 | Metabasis Therapeutics Inc | Tiromimeticos novedosos que contienen acido fosfinico. |
| ES2523045T3 (es) * | 2005-07-12 | 2014-11-20 | Warner Chilcott Company, Llc | Derivado éster de etinil estradiol |
| CN101228177A (zh) * | 2005-07-12 | 2008-07-23 | 沃纳奇尔科特公司 | 雌二醇的3-酯前药 |
| DK2450041T3 (en) | 2005-10-12 | 2018-11-19 | Unimed Pharmaceuticals Llc | Enhanced testosterone gel for use in the treatment of hypogonadism |
| US20070197488A1 (en) * | 2005-11-29 | 2007-08-23 | Olaf Peters | Prodrugs of ERbeta-selective substances, process for their production, and pharmaceutical compositions that contain these compounds |
| US20070123500A1 (en) * | 2005-11-29 | 2007-05-31 | Gerd Mueller | Prodrugs of ERbeta-selective substances, processes for their preparation and pharmaceutical compositions comprising these compounds |
| US20070135375A1 (en) * | 2005-11-30 | 2007-06-14 | Ralf Wyrwa | Sulfamoyl sulfonate prodrugs |
| US8288366B2 (en) | 2006-06-20 | 2012-10-16 | Chochinov Ronald H | Formulation for hair growth |
| PL2206727T3 (pl) | 2007-10-11 | 2015-08-31 | Daiichi Sankyo Co Ltd | Przeciwciało skierowane na białko Siglec-15 związane z osteoklastami |
| JP2012520883A (ja) * | 2009-03-16 | 2012-09-10 | アイピントゥル,エルエルシー | アルツハイマー病及び骨粗鬆症の治療並びに老化の軽減 |
| EP3541395A4 (en) | 2016-11-21 | 2020-07-01 | Viking Therapeutics, Inc. | GLYCOGENOSIS TREATMENT METHODS |
| EP3634426A4 (en) | 2017-06-05 | 2021-04-07 | Viking Therapeutics, Inc. | COMPOSITIONS FOR TREATMENT OF FIBROSE |
| CA3094167A1 (en) | 2018-03-22 | 2019-09-26 | Viking Therapeutics, Inc. | Crystalline forms and methods of producing crystalline forms of a compound |
| WO2020117962A1 (en) | 2018-12-05 | 2020-06-11 | Viking Therapeutics, Inc. | Compositions for the treatment of fibrosis and inflammation |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR6434M (es) * | 1967-02-23 | 1968-11-04 | ||
| US4041022A (en) * | 1967-05-24 | 1977-08-09 | Ciba-Geigy Corporation | Process for the manufacture of thyrocalcitonin |
| GB2138286B (en) * | 1983-04-19 | 1986-10-08 | Dr Christopher Harry Mortimer | Pharmaceutical composition for the treatment of hair loss |
| US4692433A (en) * | 1983-10-12 | 1987-09-08 | The Regents Of The University Of California | Method and composition for regulating serum calcium levels of mammals |
| JPS6089422A (ja) * | 1983-10-24 | 1985-05-20 | Kureha Chem Ind Co Ltd | 抗骨粗鬆症剤 |
| US4812304A (en) * | 1984-12-21 | 1989-03-14 | The Procter & Gamble Company | Treatment of osteoporosis |
| US4822609A (en) * | 1984-12-21 | 1989-04-18 | The Procter & Gamble Company | Treatment of osteoporosis |
| US4812311A (en) * | 1984-12-21 | 1989-03-14 | The Procter & Gamble Company | Kit for use in the treatment of osteoporosis |
| US5001118A (en) * | 1986-12-29 | 1991-03-19 | Kureha Kagaku Kogyo Kabushiki Kaisha | Method for preventing senescence and increasing bone mass |
| JP2542846B2 (ja) * | 1987-05-22 | 1996-10-09 | 日本臓器製薬株式会社 | 糖尿病治療剤 |
| US4946679A (en) * | 1988-07-25 | 1990-08-07 | Thys Jacobs Susan | Method for the treatment of premenstrual syndrome |
| US4945103A (en) * | 1989-01-17 | 1990-07-31 | Michael Cohen | Method of treating pre-menstrual syndrome |
-
1990
- 1990-10-25 US US07/603,214 patent/US5116828A/en not_active Expired - Fee Related
- 1990-10-26 DE DE69008476T patent/DE69008476T2/de not_active Expired - Fee Related
- 1990-10-26 ES ES90120567T patent/ES2055845T3/es not_active Expired - Lifetime
- 1990-10-26 AT AT9090120567T patent/ATE104854T1/de not_active IP Right Cessation
- 1990-10-26 JP JP02289657A patent/JP3113269B2/ja not_active Expired - Fee Related
- 1990-10-26 EP EP90120567A patent/EP0424954B1/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DE69008476D1 (de) | 1994-06-01 |
| EP0424954B1 (en) | 1994-04-27 |
| US5116828A (en) | 1992-05-26 |
| DE69008476T2 (de) | 1994-09-01 |
| JP3113269B2 (ja) | 2000-11-27 |
| EP0424954A1 (en) | 1991-05-02 |
| JPH03209328A (ja) | 1991-09-12 |
| ATE104854T1 (de) | 1994-05-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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