ES2055541T3 - Un proceso para la preparacion de una capa de revestimiento no cohesiva. - Google Patents

Un proceso para la preparacion de una capa de revestimiento no cohesiva.

Info

Publication number
ES2055541T3
ES2055541T3 ES91306041T ES91306041T ES2055541T3 ES 2055541 T3 ES2055541 T3 ES 2055541T3 ES 91306041 T ES91306041 T ES 91306041T ES 91306041 T ES91306041 T ES 91306041T ES 2055541 T3 ES2055541 T3 ES 2055541T3
Authority
ES
Spain
Prior art keywords
coating layer
preparing
microcapsules
medium
cohesive coating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91306041T
Other languages
English (en)
Inventor
Hiroaki Jizomoto
Koichiro Hirano
Eri Kanaoka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shionogi and Co Ltd
Original Assignee
Shionogi and Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi and Co Ltd filed Critical Shionogi and Co Ltd
Application granted granted Critical
Publication of ES2055541T3 publication Critical patent/ES2055541T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/20—After-treatment of capsule walls, e.g. hardening
    • B01J13/22—Coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5089—Processes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2984—Microcapsule with fluid core [includes liposome]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

ES UN PROCESO PARA PRODUCIR MICROCAPSULAS CON UNA CAPA DE REVESTIMIENTO NO ADHESIVA, QUE COMPRENDE LA FORMACION DE UN LODO DE MICROCAPSULAS EN UN MEDIO ACUOSO SELECCIONADO, UNO O MAS SOLVENTES ORGANICOS O UNA MEZCLA DE ELLOS POR UN METODO DE COACERVACION, AÑADIENDO POLVOS DE UN COMPUESTO INORGANICO, FARMACEUTICAMENTE ACEPTABLE QUE SEA INSOLUBLE EN DICHO MEDIO Y EN DICHO LODO, DE TAL MANERA QUE DICHO COMPUESTO INORGANICO SE ADHIERA A TODA LA SUPERFICIE DE DICHA CAPA DE REVESTIMIENTO ADHESIVA Y LA SEPARACION DE LAS CAPSULAS DE DICHO MEDIO
ES91306041T 1990-07-04 1991-07-03 Un proceso para la preparacion de una capa de revestimiento no cohesiva. Expired - Lifetime ES2055541T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP17809790 1990-07-04

Publications (1)

Publication Number Publication Date
ES2055541T3 true ES2055541T3 (es) 1994-08-16

Family

ID=16042590

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91306041T Expired - Lifetime ES2055541T3 (es) 1990-07-04 1991-07-03 Un proceso para la preparacion de una capa de revestimiento no cohesiva.

Country Status (8)

Country Link
US (1) US5480655A (es)
EP (1) EP0465238B1 (es)
JP (1) JP3179132B2 (es)
KR (1) KR0168850B1 (es)
AT (1) ATE103806T1 (es)
DE (1) DE69101594T2 (es)
DK (1) DK0465238T3 (es)
ES (1) ES2055541T3 (es)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4310076A1 (de) * 1993-03-27 1994-09-29 Boehringer Ingelheim Kg Neue Suspensionsformulierungen
JP3625940B2 (ja) * 1996-01-29 2005-03-02 信越化学工業株式会社 水系液のカプセルおよびその製造方法
EP1393706A1 (en) * 2002-08-14 2004-03-03 Quest International B.V. Fragranced compositions comprising encapsulated material
EP1534216B1 (en) * 2002-08-14 2017-01-04 Givaudan S.A. Compositions comprising encapsulated material
ES2665464T3 (es) * 2003-03-28 2018-04-25 Sigmoid Pharma Limited Forma de dosificación oral sólida que contiene microcápsulas sin costuras
JP2005036001A (ja) * 2003-07-03 2005-02-10 Shiseido Co Ltd 油性粒子を含有する外用組成物
WO2006003733A1 (ja) * 2004-07-02 2006-01-12 Shiseido Company, Ltd. 油性粒子を含有する外用組成物
CA2581775A1 (en) * 2004-09-27 2006-04-06 Sigmoid Biotechnologies Limited Dihydropyrimidine microcapsule - formulations
JP2010523554A (ja) * 2007-04-04 2010-07-15 シグモイド・ファーマ・リミテッド タクロリムスの医薬組成物
ES2963291T3 (es) * 2007-04-26 2024-03-26 Sublimity Therapeutics Ltd Fabricación de múltiples minicápsulas
CA2685591A1 (en) * 2007-05-01 2008-11-06 Sigmoid Pharma Limited Pharmaceutical nimodipine compositions
CA2762179A1 (en) 2009-05-18 2010-11-25 Sigmoid Pharma Limited Composition comprising oil drops
IN2012DN00781A (es) 2009-08-12 2015-06-26 Sigmoid Pharma Ltd
KR100978583B1 (ko) * 2009-09-02 2010-08-27 (주)바이오제닉스 화장품용 색조캡슐 조성물, 이의 제조방법 및 이를 이용한 화장품 제제
BR112013006381B1 (pt) 2010-09-20 2024-02-15 Spi Pharma Inc Composição que compreende um material de núcleo tendo um valor de sabor e um revestimento polimérico e formulação farmacêutica
GB201020032D0 (en) 2010-11-25 2011-01-12 Sigmoid Pharma Ltd Composition
BR112013029422B1 (pt) * 2011-06-07 2021-12-28 Firmenich Sa Cápsulas núcleo-revestimento
GB201212010D0 (en) 2012-07-05 2012-08-22 Sigmoid Pharma Ltd Formulations
GB201319791D0 (en) 2013-11-08 2013-12-25 Sigmoid Pharma Ltd Formulations
ES2858517T3 (es) 2014-11-07 2021-09-30 Sublimity Therapeutics Ltd Composiciones que comprenden ciclosporina
JP6768551B2 (ja) * 2017-02-17 2020-10-14 テクノロジック スリー エス．アール．エル．Ｔｅｃｎｏｌｏｇｉｃ ３ Ｓ．ｒ．ｌ． ボルトおよびナットを封止し、遮断するための嫌気性硬化性配合物

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL262194A (es) * 1960-03-10 1900-01-01
US3137630A (en) * 1961-06-09 1964-06-16 Eastman Kodak Co Process for preparing a dry, finely divided, gelatin particle product
NL6710475A (es) * 1966-07-30 1968-01-31
NL136382C (es) * 1966-10-28
FR2420994A1 (fr) * 1978-03-30 1979-10-26 Pentel Kk Microcapsules ayant une paroi en substance minerale et procede de leur preparation
US4464317A (en) * 1980-01-28 1984-08-07 The Washington University Method of encapsulating active agents with inorganic coatings
DE3016189A1 (de) * 1980-04-26 1981-10-29 Bayer Ag, 5090 Leverkusen Lagerbestaendige, pflanzenbehandlungsmittel enthaltende mikrokapsel-suspensionen, verfahren zu deren herstellung und deren verwendung
US4479911A (en) * 1982-01-28 1984-10-30 Sandoz, Inc. Process for preparation of microspheres and modification of release rate of core material
JPS6210087A (ja) * 1985-07-03 1987-01-19 Shionogi & Co Ltd ４，７−ジヒドロチエノ〔２，３−ｂ〕ピリジン誘導体，その製造法および循環器系疾患治療剤
US4966770A (en) * 1989-07-26 1990-10-30 Himedics, Inc. Prednisone microencapsulated granules
US5013557A (en) * 1989-10-03 1991-05-07 Warner-Lambert Company Taste masking compositions comprising spray dried microcapsules containing sucralfate and methods for preparing same

Also Published As

Publication number Publication date
ATE103806T1 (de) 1994-04-15
JP3179132B2 (ja) 2001-06-25
EP0465238A1 (en) 1992-01-08
DE69101594T2 (de) 1994-07-21
DE69101594D1 (de) 1994-05-11
JPH04358533A (ja) 1992-12-11
KR920002217A (ko) 1992-02-28
US5480655A (en) 1996-01-02
KR0168850B1 (ko) 1999-01-15
DK0465238T3 (da) 1994-05-02
EP0465238B1 (en) 1994-04-06

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