ES2054601T3 - Proteina con actividad de tipo citoquina, adn recombinante codante para esta proteina, celulas y microorganismos transformados. - Google Patents

Proteina con actividad de tipo citoquina, adn recombinante codante para esta proteina, celulas y microorganismos transformados.

Info

Publication number
ES2054601T3
ES2054601T3 ES92400858T ES92400858T ES2054601T3 ES 2054601 T3 ES2054601 T3 ES 2054601T3 ES 92400858 T ES92400858 T ES 92400858T ES 92400858 T ES92400858 T ES 92400858T ES 2054601 T3 ES2054601 T3 ES 2054601T3
Authority
ES
Spain
Prior art keywords
protein
cells
type activity
recombinant dna
transformed microorganisms
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92400858T
Other languages
English (en)
Other versions
ES2054601T1 (es
Inventor
Daniel Caput
Pascual Ferrara
Jean-Claude Guillemot
Mourad Kaghad
Bouteiller Christine Labit-Le
Pascal Leplatois
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi SA
Original Assignee
Sanofi SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR9103904A external-priority patent/FR2674537B1/fr
Priority claimed from FR9200137A external-priority patent/FR2685919B1/fr
Application filed by Sanofi SA filed Critical Sanofi SA
Publication of ES2054601T1 publication Critical patent/ES2054601T1/es
Application granted granted Critical
Publication of ES2054601T3 publication Critical patent/ES2054601T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/5446—IL-16
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/5437—IL-13
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F02—COMBUSTION ENGINES; HOT-GAS OR COMBUSTION-PRODUCT ENGINE PLANTS
    • F02B—INTERNAL-COMBUSTION PISTON ENGINES; COMBUSTION ENGINES IN GENERAL
    • F02B75/00—Other engines
    • F02B75/02—Engines characterised by their cycles, e.g. six-stroke
    • F02B2075/022—Engines characterised by their cycles, e.g. six-stroke having less than six strokes per cycle
    • F02B2075/027—Engines characterised by their cycles, e.g. six-stroke having less than six strokes per cycle four

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)

Abstract

PROTEINA DE ACTIVIDAD DE TIPO CITOQUINA, ADN RECOMBINANTE CODIFICANTE PARA ESTA PROTEINA, CELULA Y MICROORGANISMOS TRANSFORMADOS. LA PRESENTE INVENCION SE REFIERE A UNA PROTEINA DE ACTIVIDAD DE TIPO CITOQUINA, O UN PRECURSOR DE ESTA PROTEINA, QUE COMPRENDE LA SIGUIENTE SECUENCIA DE AMINOACIDOS (A1): EN LA QUE XAA REPRESENTA ASP O GLY.
ES92400858T 1991-03-29 1992-03-27 Proteina con actividad de tipo citoquina, adn recombinante codante para esta proteina, celulas y microorganismos transformados. Expired - Lifetime ES2054601T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9103904A FR2674537B1 (fr) 1991-03-29 1991-03-29 Proteine a activite de type cytokine, adn recombinant codant pour cette proteine, cellules animales transformees.
FR9200137A FR2685919B1 (fr) 1992-01-08 1992-01-08 Proteine a activite de type cytokine, adn recombinant codant pour cette proteine, cellules animales transformees.

Publications (2)

Publication Number Publication Date
ES2054601T1 ES2054601T1 (es) 1994-08-16
ES2054601T3 true ES2054601T3 (es) 1996-04-01

Family

ID=26228598

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92400858T Expired - Lifetime ES2054601T3 (es) 1991-03-29 1992-03-27 Proteina con actividad de tipo citoquina, adn recombinante codante para esta proteina, celulas y microorganismos transformados.

Country Status (14)

Country Link
US (1) US5652123A (es)
EP (1) EP0506574B1 (es)
JP (1) JP2865423B2 (es)
AT (1) ATE130869T1 (es)
CA (1) CA2083826C (es)
DE (2) DE506574T1 (es)
DK (1) DK0506574T3 (es)
ES (1) ES2054601T3 (es)
GR (2) GR940300052T1 (es)
HK (1) HK1007435A1 (es)
HU (2) HU217099B (es)
IE (1) IE72165B1 (es)
MD (1) MD1652G2 (es)
WO (1) WO1992017586A1 (es)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07508179A (ja) * 1992-08-21 1995-09-14 シェリング・コーポレーション ヒトインターロイキン−１３
US5596072A (en) * 1992-08-21 1997-01-21 Schering Corporation Method of refolding human IL-13
US6274711B1 (en) 1993-06-14 2001-08-14 Inserm, Institut National De La Sante Et De La Recherche Medicale Purified mammalian CTLA-8 antigens and related reagents
BR9607403A (pt) * 1995-02-10 1998-07-07 Novo Nordisk As Protease cultura biologicamente pura isolada processos de preparação de uma protease e de lavagem uso de uma protease composição detergente aditivo de detergente
CN1093174C (zh) * 1995-02-10 2002-10-23 诺沃奇梅兹有限公司 芽孢杆菌属蛋白酶
US6576232B1 (en) * 1998-04-03 2003-06-10 The Penn State Research Foundation IL13 mutants
ES2277460T3 (es) 1998-12-14 2007-07-01 Genetics Institute, Llc Cadena del receptor de la citoquina.
US7553487B2 (en) 1998-12-14 2009-06-30 Genetics Institute, Llc Method and compositions for treating asthma
EP1268794A2 (en) 2000-04-07 2003-01-02 Heska Corporation Compositions and methods related to canine igg and canine il-13 receptors
US20070104710A1 (en) * 2002-06-28 2007-05-10 Domants Limited Ligand that has binding specificity for IL-4 and/or IL-13
US20110223168A1 (en) * 2002-12-27 2011-09-15 Greg Winter Ligand that has binding specificity for il-4 and/or il-13
US20050059024A1 (en) 2003-07-25 2005-03-17 Ambion, Inc. Methods and compositions for isolating small RNA molecules
DK2805728T3 (da) * 2003-12-23 2020-04-20 Genentech Inc Hidtil ukendte anti-IL13-antistoffer og anvendelser deraf
AR049390A1 (es) 2004-06-09 2006-07-26 Wyeth Corp Anticuerpos contra la interleuquina-13 humana y usos de los mismos
US20090098142A1 (en) * 2004-06-09 2009-04-16 Kasaian Marion T Methods and compositions for treating and monitoring treatment of IL-13-associated disorders
US7501121B2 (en) 2004-06-17 2009-03-10 Wyeth IL-13 binding agents
WO2006055638A2 (en) 2004-11-17 2006-05-26 Abgenix, Inc. Fully human monoclonal antibodies to il-13
WO2006124451A2 (en) * 2005-05-11 2006-11-23 Centocor, Inc. Anti-il-13 antibodies, compositions, methods and uses
WO2007036745A2 (en) 2005-09-30 2007-04-05 Medimmune Limited Interleukin-13 antibody composition
KR101544108B1 (ko) * 2006-09-08 2015-08-13 애브비 바하마스 리미티드 인터루킨-13 결합 단백질
JP2010527916A (ja) * 2007-04-23 2010-08-19 ワイス・エルエルシー Ｉｌ−１３関連障害を治療する方法および組成物ならびにその治療をモニターする方法
AU2009283008A1 (en) * 2008-08-20 2010-02-25 Centocor Ortho Biotech Inc. Engineered anti-IL-13 antibodies, compositions, methods and uses
GB0904214D0 (en) * 2009-03-11 2009-04-22 Ucb Pharma Sa Biological products
FR2957799B1 (fr) 2010-03-26 2012-08-17 Inst Des Vaisseaux Et Du Sang Compositions proangiogeniques, leur procede de preparation et leurs utilisations
SG10201802525QA (en) 2013-09-13 2018-04-27 Genentech Inc Methods and compositions comprising purified recombinant polypeptides
KR102332302B1 (ko) 2013-09-13 2021-12-01 제넨테크, 인크. 세포주에서 숙주 세포 단백질 및 재조합 폴리펩티드 생성물을 검출 및 정량화하기 위한 조성물 및 방법

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL92685A0 (en) * 1988-12-16 1990-09-17 Us Commerce Dna encoding lymphokine/cytokine like proteins,cells transformed thereby and production of said proteins and antibodies against them

Also Published As

Publication number Publication date
EP0506574B1 (fr) 1995-11-29
US5652123A (en) 1997-07-29
HU217099B (hu) 1999-11-29
CA2083826A1 (en) 1992-09-30
WO1992017586A1 (fr) 1992-10-15
DE69206301T2 (de) 1996-06-13
GR940300052T1 (en) 1994-08-31
MD1652G2 (ro) 2001-12-31
IE72165B1 (en) 1997-03-26
GR3019043T3 (en) 1996-05-31
CA2083826C (en) 1999-04-27
HU9203753D0 (en) 1993-03-29
JPH06500567A (ja) 1994-01-20
DK0506574T3 (da) 1996-04-09
MD1652F2 (en) 2001-04-30
HK1007435A1 (en) 1999-04-09
HUT68162A (en) 1995-05-29
ES2054601T1 (es) 1994-08-16
MD970099A (en) 1998-04-30
EP0506574A1 (fr) 1992-09-30
JP2865423B2 (ja) 1999-03-08
ATE130869T1 (de) 1995-12-15
DE69206301D1 (de) 1996-01-11
IE921016A1 (en) 1992-10-07
DE506574T1 (de) 1994-11-17

Similar Documents

Publication Publication Date Title
ES2054601T3 (es) Proteina con actividad de tipo citoquina, adn recombinante codante para esta proteina, celulas y microorganismos transformados.
DE69128754D1 (de) Merschliches CNP-Gen und Vorläufer protein
NZ504548A (en) Polypeptides and nucleic acids encoding human chordin
NZ503100A (en) 2-deoxyglucose-6-phosphate (2-DOG-6-P) phosphatase DNA sequences as selection markers in plants
UA84666C2 (ru) ВЫДеЛЕНнЫЙ ПОЛИНУКЛЕОТИД, КОДИРУЮЩИЙ СЛИТОЙ ПРОТЕИН С ПЕСТИЦИДНОЙ АКТИВНОСТЬЮ, И ТРАНСГЕННАЯ КЛЕТКА-ХОЗЯИН
WO1999003881A3 (fr) Polypeptide chimerique comprenant le fragment b de la toxine shiga et des peptides d'interet therapeutique
ES2095243T3 (es) Proteina de actividad urato oxidasa; gen recombinante codante para esta, vector de expresion, micro-organismos y celulas transformadas.
ATE248918T1 (de) Rekombinante dnase b aus streptococcus pyogenes
CA2253006A1 (en) .beta.-carotene hydroxylase gene
EP0427863A4 (en) Dna coding for protein capable of combining with enhancer of alpha-fetoprotein gene
DE69231940D1 (de) Rekombinant DNS kodierend für eine Endochitinase
ATE61631T1 (de) Gen fuer ein protein mit insektizider wirkung.
EP0919621A4 (en) HUMAN TAK1 AND DNA CODING THEM
RU97103147A (ru) Днк-последовательности, кодирующие человеческие протеины тх и ту, родственные конвергирующему интерлейкин-1-бета ферменту
PT676413E (pt) Proteina de ligacao a interferoes alfa/beta, sua preparacao e utilizacao
AU654155B2 (en) A DNA encoding a protein which binds to the enhancer of alpha-fetoprotein gene
EP1013665A4 (en) NEW POLYPEPTIDE DEPLOYING WATER CIRCULATION ACTIVITY AND DNA SEQUENCE
DE69534738D1 (de) Leukocyten-aktivierender Faktor
DE69733026D1 (de) Cyclin e spezifische konstrukte und komplexe
CA2244928A1 (en) Dna coding for serine/threonine kinase
EP1295943A4 (en) POLYPEPTIDES CAPABLE THE POWER TO STIMULATE NEUTROPHILES
IT1262997B (it) Composto proteico e sequenze nucleotidiche codificanti per esso.
WO1999060117A3 (fr) Polypeptide prax-1
EP0953642A4 (en) ANTIGENIC PROTEIN DRAWN FROM THE INFECTIOUS LARYNGO-TRACHEITIS VIRUS

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 506574

Country of ref document: ES