DE69206301D1 - Protein mit der Aktivität vom Typ von Cytokin, dafür kodierende rekombinante DNS, transformierte Zellen und Mikroorganismen. - Google Patents

Protein mit der Aktivität vom Typ von Cytokin, dafür kodierende rekombinante DNS, transformierte Zellen und Mikroorganismen.

Info

Publication number
DE69206301D1
DE69206301D1 DE69206301T DE69206301T DE69206301D1 DE 69206301 D1 DE69206301 D1 DE 69206301D1 DE 69206301 T DE69206301 T DE 69206301T DE 69206301 T DE69206301 T DE 69206301T DE 69206301 D1 DE69206301 D1 DE 69206301D1
Authority
DE
Germany
Prior art keywords
protein
activity
microorganisms
recombinant dna
transformed cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69206301T
Other languages
English (en)
Other versions
DE69206301T2 (de
Inventor
Daniel Caput
Pascual Ferrara
Jean-Claude Guillemot
Mourad Kaghad
Bouteiller Christine Labit-Le
Pascal Leplatois
Marilyn Magazin
Adrian Minty
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Sanofi SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR9103904A external-priority patent/FR2674537B1/fr
Priority claimed from FR9200137A external-priority patent/FR2685919B1/fr
Application filed by Sanofi SA filed Critical Sanofi SA
Publication of DE69206301D1 publication Critical patent/DE69206301D1/de
Application granted granted Critical
Publication of DE69206301T2 publication Critical patent/DE69206301T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/54Interleukins [IL]
    • C07K14/5446IL-16
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/54Interleukins [IL]
    • C07K14/5437IL-13
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244Interleukins [IL]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F02COMBUSTION ENGINES; HOT-GAS OR COMBUSTION-PRODUCT ENGINE PLANTS
    • F02BINTERNAL-COMBUSTION PISTON ENGINES; COMBUSTION ENGINES IN GENERAL
    • F02B75/00Other engines
    • F02B75/02Engines characterised by their cycles, e.g. six-stroke
    • F02B2075/022Engines characterised by their cycles, e.g. six-stroke having less than six strokes per cycle
    • F02B2075/027Engines characterised by their cycles, e.g. six-stroke having less than six strokes per cycle four

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
DE69206301T 1991-03-29 1992-03-27 Protein mit der Aktivität vom Typ von Cytokin, dafür kodierende rekombinante DNS, transformierte Zellen und Mikroorganismen. Expired - Lifetime DE69206301T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9103904A FR2674537B1 (fr) 1991-03-29 1991-03-29 Proteine a activite de type cytokine, adn recombinant codant pour cette proteine, cellules animales transformees.
FR9200137A FR2685919B1 (fr) 1992-01-08 1992-01-08 Proteine a activite de type cytokine, adn recombinant codant pour cette proteine, cellules animales transformees.

Publications (2)

Publication Number Publication Date
DE69206301D1 true DE69206301D1 (de) 1996-01-11
DE69206301T2 DE69206301T2 (de) 1996-06-13

Family

ID=26228598

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69206301T Expired - Lifetime DE69206301T2 (de) 1991-03-29 1992-03-27 Protein mit der Aktivität vom Typ von Cytokin, dafür kodierende rekombinante DNS, transformierte Zellen und Mikroorganismen.
DE0506574T Pending DE506574T1 (de) 1991-03-29 1992-03-27 Protein mit Cytokinaktivität, dafür kodierende rekombinante DNS, transformierte Zellen und Mikroorganismen.

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE0506574T Pending DE506574T1 (de) 1991-03-29 1992-03-27 Protein mit Cytokinaktivität, dafür kodierende rekombinante DNS, transformierte Zellen und Mikroorganismen.

Country Status (14)

Country Link
US (1) US5652123A (de)
EP (1) EP0506574B1 (de)
JP (1) JP2865423B2 (de)
AT (1) ATE130869T1 (de)
CA (1) CA2083826C (de)
DE (2) DE69206301T2 (de)
DK (1) DK0506574T3 (de)
ES (1) ES2054601T3 (de)
GR (2) GR940300052T1 (de)
HK (1) HK1007435A1 (de)
HU (2) HU217099B (de)
IE (1) IE72165B1 (de)
MD (1) MD1652G2 (de)
WO (1) WO1992017586A1 (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5596072A (en) * 1992-08-21 1997-01-21 Schering Corporation Method of refolding human IL-13
EP0656947A1 (de) * 1992-08-21 1995-06-14 Schering Corporation Menschliches interleukin-13
US6274711B1 (en) 1993-06-14 2001-08-14 Inserm, Institut National De La Sante Et De La Recherche Medicale Purified mammalian CTLA-8 antigens and related reagents
BR9607404A (pt) * 1995-02-10 1998-07-07 Novo Nordisk Protease cultura biologicamente pura isolada processos de preparação de uma protease e de lavagem uso de uma protease composição detergente e aditivo de detergente
WO1996024666A1 (en) * 1995-02-10 1996-08-15 Novo Nordisk A/S Bacillus proteases
US6576232B1 (en) * 1998-04-03 2003-06-10 The Penn State Research Foundation IL13 mutants
US7553487B2 (en) 1998-12-14 2009-06-30 Genetics Institute, Llc Method and compositions for treating asthma
CA2356779C (en) 1998-12-14 2012-03-13 Genetics Institute, Inc. Cytokine receptor chain
AU2001253282A1 (en) * 2000-04-07 2001-10-23 Heska Corporation Compositions and methods related to canine igg and canine il-13 receptors
US20070104710A1 (en) * 2002-06-28 2007-05-10 Domants Limited Ligand that has binding specificity for IL-4 and/or IL-13
US20110223168A1 (en) * 2002-12-27 2011-09-15 Greg Winter Ligand that has binding specificity for il-4 and/or il-13
US20050059024A1 (en) * 2003-07-25 2005-03-17 Ambion, Inc. Methods and compositions for isolating small RNA molecules
SI2805728T1 (sl) * 2003-12-23 2020-07-31 Genentech, Inc. Nova protitelesa proti il 13 in uporabe le-teh
US7501121B2 (en) 2004-06-17 2009-03-10 Wyeth IL-13 binding agents
US20090098142A1 (en) * 2004-06-09 2009-04-16 Kasaian Marion T Methods and compositions for treating and monitoring treatment of IL-13-associated disorders
AR049390A1 (es) 2004-06-09 2006-07-26 Wyeth Corp Anticuerpos contra la interleuquina-13 humana y usos de los mismos
DE602005025525D1 (de) 2004-11-17 2011-02-03 Amgen Inc Vollständige humane monoklonale antikörper gegen il-13
US20080044420A1 (en) * 2005-05-11 2008-02-21 Heavner George A Anti-IL-13 antibodies, compositions, methods and uses
SI1942939T2 (sl) * 2005-09-30 2021-11-30 Medimmune Limited Sestavek protitelesa proti interlevkinu-13
RU2472807C2 (ru) 2006-09-08 2013-01-20 Эбботт Лэборетриз Интерлейкин-13-связывающие белки
BRPI0810561A2 (pt) * 2007-04-23 2019-09-24 Wyeth Corp métodos e composições para tratar e monitorar tratamento de desordens associadas à il-13.
AU2009283008A1 (en) 2008-08-20 2010-02-25 Centocor Ortho Biotech Inc. Engineered anti-IL-13 antibodies, compositions, methods and uses
GB0904214D0 (en) 2009-03-11 2009-04-22 Ucb Pharma Sa Biological products
FR2957799B1 (fr) * 2010-03-26 2012-08-17 Inst Des Vaisseaux Et Du Sang Compositions proangiogeniques, leur procede de preparation et leurs utilisations
EP3683232A1 (de) 2013-09-13 2020-07-22 F. Hoffmann-La Roche AG Verfahren und zusammensetzungen mit gereinigten rekombinanten polypeptiden
MX2016002799A (es) 2013-09-13 2016-05-26 Genentech Inc Composiciones y metodos para detectar y cuantificar la proteina en la celula hospedera en las lineas de celulas y productos de polipeptidos recombinantes.

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL92685A0 (en) * 1988-12-16 1990-09-17 Us Commerce Dna encoding lymphokine/cytokine like proteins,cells transformed thereby and production of said proteins and antibodies against them

Also Published As

Publication number Publication date
MD1652G2 (ro) 2001-12-31
ES2054601T3 (es) 1996-04-01
CA2083826A1 (en) 1992-09-30
ATE130869T1 (de) 1995-12-15
HU217099B (hu) 1999-11-29
HUT68162A (en) 1995-05-29
MD1652F2 (en) 2001-04-30
GR3019043T3 (en) 1996-05-31
JP2865423B2 (ja) 1999-03-08
MD970099A (en) 1998-04-30
US5652123A (en) 1997-07-29
DK0506574T3 (da) 1996-04-09
DE69206301T2 (de) 1996-06-13
JPH06500567A (ja) 1994-01-20
IE72165B1 (en) 1997-03-26
HK1007435A1 (en) 1999-04-09
IE921016A1 (en) 1992-10-07
ES2054601T1 (es) 1994-08-16
EP0506574A1 (de) 1992-09-30
EP0506574B1 (de) 1995-11-29
CA2083826C (en) 1999-04-27
GR940300052T1 (en) 1994-08-31
DE506574T1 (de) 1994-11-17
HU9203753D0 (en) 1993-03-29
WO1992017586A1 (fr) 1992-10-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: SANOFI-SYNTHELABO, PARIS, FR

8327 Change in the person/name/address of the patent owner

Owner name: SANOFI-AVENTIS, PARIS, FR