ES2053562T3 - Irradiacion gamma de mezclas de colageno y un mineral. - Google Patents

Irradiacion gamma de mezclas de colageno y un mineral.

Info

Publication number
ES2053562T3
ES2053562T3 ES87309810T ES87309810T ES2053562T3 ES 2053562 T3 ES2053562 T3 ES 2053562T3 ES 87309810 T ES87309810 T ES 87309810T ES 87309810 T ES87309810 T ES 87309810T ES 2053562 T3 ES2053562 T3 ES 2053562T3
Authority
ES
Spain
Prior art keywords
mineral
gamma irradiation
collagen mixtures
collagen
mixtures
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES87309810T
Other languages
English (en)
Inventor
Thomas L Smestad
Daniel Prows
George H Chu
Diana M Hendriks
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Collagen Aesthetics Inc
Original Assignee
Collagen Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Collagen Corp filed Critical Collagen Corp
Application granted granted Critical
Publication of ES2053562T3 publication Critical patent/ES2053562T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
    • A61L2/0029—Radiation
    • A61L2/0035—Gamma radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A61L27/46—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with phosphorus-containing inorganic fillers
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S128/00—Surgery
    • Y10S128/08—Collagen
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S623/00—Prosthesis, i.e. artificial body members, parts thereof, or aids and accessories therefor
    • Y10S623/92—Method or apparatus for preparing or treating prosthetic
    • Y10S623/923—Bone

Abstract

UN PROCEDIMIENTO PARA ESTERILIZACION DE COMPOSICIONES DE COLAGENO/MINERAL UTILIZANDO RADIACION GAMMA SE LLEVA A CABO EN CONDICIONES QUE GENERAN UN PRODUCTO CON PROPIEDADES DE MANEJO Y DE BIOCOMPATIBILIDAD DESEADAS.
ES87309810T 1986-11-06 1987-11-05 Irradiacion gamma de mezclas de colageno y un mineral. Expired - Lifetime ES2053562T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/928,306 US4865602A (en) 1986-11-06 1986-11-06 Gamma irradiation of collagen/mineral mixtures
CA000616394A CA1320451C (en) 1986-11-06 1992-06-02 Gamma irradiation of collagen/mineral mixtures

Publications (1)

Publication Number Publication Date
ES2053562T3 true ES2053562T3 (es) 1994-08-01

Family

ID=25673243

Family Applications (1)

Application Number Title Priority Date Filing Date
ES87309810T Expired - Lifetime ES2053562T3 (es) 1986-11-06 1987-11-05 Irradiacion gamma de mezclas de colageno y un mineral.

Country Status (7)

Country Link
US (3) US4865602A (es)
EP (1) EP0270254B1 (es)
JP (2) JPH062151B2 (es)
AU (1) AU603744B2 (es)
CA (1) CA1320451C (es)
ES (1) ES2053562T3 (es)
GR (1) GR3007382T3 (es)

Families Citing this family (101)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4888366A (en) * 1984-10-24 1989-12-19 Collagen Corporation Inductive collagen-based bone repair preparations
US5001169A (en) * 1984-10-24 1991-03-19 Collagen Corporation Inductive collagen-based bone repair preparations
US5246457A (en) * 1985-03-28 1993-09-21 Collagen Corporation Xenogeneic collagen/mineral preparations in bone repair
US4865602A (en) * 1986-11-06 1989-09-12 Collagen Corporation Gamma irradiation of collagen/mineral mixtures
GB8708009D0 (en) * 1987-04-03 1987-05-07 Clayton Found Res Injectable soft tissue augmentation materials
US5735902A (en) * 1987-07-20 1998-04-07 Regen Biologics, Inc. Hand implant device
US5306311A (en) * 1987-07-20 1994-04-26 Regen Corporation Prosthetic articular cartilage
IT1215881B (it) * 1988-02-16 1990-02-22 Giancarlo Foresti Sussidio chirurgico ad azione osteotropa.
DE68928975T2 (de) * 1988-08-10 1999-10-28 Nitta Gelatin Kk Aushärtender Werkstoff für ärztlichen und zahnärztlichen Gebrauch
US5643464A (en) * 1988-11-21 1997-07-01 Collagen Corporation Process for preparing a sterile, dry crosslinking agent
DE69331096T2 (de) * 1992-02-28 2002-08-14 Cohesion Tech Inc Injektierbare, keramische verbindungen sowie verfahren zur deren herstellung und anwendung
US5204382A (en) * 1992-02-28 1993-04-20 Collagen Corporation Injectable ceramic compositions and methods for their preparation and use
US5358935A (en) * 1992-11-19 1994-10-25 Robert Allen Smith Nonantigenic keratinous protein material
US5362442A (en) * 1993-07-22 1994-11-08 2920913 Canada Inc. Method for sterilizing products with gamma radiation
US20040067157A1 (en) * 1993-07-22 2004-04-08 Clearant, Inc. Methods for sterilizing biological materials
US5531791A (en) * 1993-07-23 1996-07-02 Bioscience Consultants Composition for repair of defects in osseous tissues, method of making, and prosthesis
JP2775386B2 (ja) * 1993-10-04 1998-07-16 科学技術庁無機材質研究所長 アパタイト・有機物複合体とその製造法
US5721150A (en) * 1993-10-25 1998-02-24 Lsi Logic Corporation Use of silicon for integrated circuit device interconnection by direct writing of patterns therein
US5422068A (en) * 1994-01-05 1995-06-06 Shalaby; Shalaby W. Radiochemical sterilization
US6337389B1 (en) * 1995-03-17 2002-01-08 Bioscience Consultants, L.L.C. Method and process for the production of collagen preparations from invertebrate marine animals and compositions thereof
US5674292A (en) 1995-06-07 1997-10-07 Stryker Corporation Terminally sterilized osteogenic devices and preparation thereof
ES2260783T3 (es) * 1996-01-17 2006-11-01 Osteotech, Inc. Procedimiento para producir laminas flexibles a partir de particulas oseas alargadas y desmineralizadas.
US5788941A (en) * 1996-01-31 1998-08-04 Steris Corporation Method of sterilization of bone tussue
US8865788B2 (en) * 1996-02-13 2014-10-21 The General Hospital Corporation Radiation and melt treated ultra high molecular weight polyethylene prosthetic devices
US8563623B2 (en) * 1996-02-13 2013-10-22 The General Hospital Corporation Radiation melt treated ultra high molecular weight polyethylene prosthetic devices
US20020156536A1 (en) * 1996-02-13 2002-10-24 Harris William H. Polyethylene hip joint prosthesis with extended range of motion
US5792478A (en) * 1996-07-08 1998-08-11 Advanced Uro Science Tissue injectable composition and method of use
US6083522A (en) * 1997-01-09 2000-07-04 Neucoll, Inc. Devices for tissue repair and methods for preparation and use thereof
US6017366A (en) * 1997-04-18 2000-01-25 W. L. Gore & Associates, Inc. Resorbable interposition arthroplasty implant
US5889075A (en) * 1997-10-10 1999-03-30 United States Surgical Corporation Irradiated surgical suture and method for making same
US20040081704A1 (en) * 1998-02-13 2004-04-29 Centerpulse Biologics Inc. Implantable putty material
ES2247817T3 (es) * 1998-07-06 2006-03-01 Nanobac Oy Metodo para la erradicacion de nanobacterias.
US6706290B1 (en) 1998-07-06 2004-03-16 Olvai E. Kajander Methods for eradication of nanobacteria
FR2786400B1 (fr) * 1998-11-30 2002-05-10 Imedex Biomateriaux Procede de preparation d'un materiau collagenique a vitesse de biodegradation in vivo controlee et materiaux obtenus
ATE253385T1 (de) 1999-02-04 2003-11-15 Sdgi Holdings Inc Hochmineralisierte osteogene schwammzusammensetzungen und ihre verwendung
DE60020526T2 (de) * 1999-02-04 2006-05-11 SDGI Holdings, Inc., Wilmington Osteogene pastenzusammensetzungen und ihre verwendung
US20030228288A1 (en) 1999-10-15 2003-12-11 Scarborough Nelson L. Volume maintaining osteoinductive/osteoconductive compositions
KR20030011279A (ko) * 2000-03-23 2003-02-07 클리어런트, 인코포레이티드 생물학적 성분의 살균방법
US20040086420A1 (en) * 2000-03-23 2004-05-06 Macphee Martin J. Methods for sterilizing serum or plasma
US9387094B2 (en) * 2000-07-19 2016-07-12 Warsaw Orthopedic, Inc. Osteoimplant and method of making same
JP4354181B2 (ja) * 2000-07-31 2009-10-28 ザ・ジェネラル・ホスピタル・コーポレイション 転位の危険性を減少させる改良された寛骨臼コンポーネント
US7323193B2 (en) * 2001-12-14 2008-01-29 Osteotech, Inc. Method of making demineralized bone particles
US20020114795A1 (en) * 2000-12-22 2002-08-22 Thorne Kevin J. Composition and process for bone growth and repair
US20020115742A1 (en) * 2001-02-22 2002-08-22 Trieu Hai H. Bioactive nanocomposites and methods for their use
US6682695B2 (en) * 2001-03-23 2004-01-27 Clearant, Inc. Methods for sterilizing biological materials by multiple rates
US6696060B2 (en) 2001-06-14 2004-02-24 Clearant, Inc. Methods for sterilizing preparations of monoclonal immunoglobulins
US7105182B2 (en) 2001-07-25 2006-09-12 Szymaitis Dennis W Periodontal regeneration composition and method of using same
US20030026770A1 (en) * 2001-07-25 2003-02-06 Szymaitis Dennis W. Periodontal regeneration composition and method of using same
US6946098B2 (en) 2001-08-10 2005-09-20 Clearant, Inc. Methods for sterilizing biological materials
US6749851B2 (en) 2001-08-31 2004-06-15 Clearant, Inc. Methods for sterilizing preparations of digestive enzymes
US7252799B2 (en) * 2001-08-31 2007-08-07 Clearant, Inc. Methods for sterilizing preparations containing albumin
US20050152986A1 (en) * 2001-09-06 2005-07-14 Nicolaas Duneas Cross-linked collagenous biomaterial
US20030095890A1 (en) * 2001-09-24 2003-05-22 Shirley Miekka Methods for sterilizing biological materials containing non-aqueous solvents
US20030185702A1 (en) * 2002-02-01 2003-10-02 Wilson Burgess Methods for sterilizing tissue
US20110091353A1 (en) * 2001-09-24 2011-04-21 Wilson Burgess Methods for Sterilizing Tissue
WO2003030956A2 (en) * 2001-10-12 2003-04-17 Osteotech, Inc. Improved bone graft
US20030124023A1 (en) * 2001-12-21 2003-07-03 Wilson Burgess Method of sterilizing heart valves
US20030181371A1 (en) * 2001-12-28 2003-09-25 Angiotech Pharmaceuticals, Inc. Compositions and methods of using collajolie
US20030180181A1 (en) * 2002-02-01 2003-09-25 Teri Greib Methods for sterilizing tissue
US7455854B2 (en) * 2002-04-18 2008-11-25 University Of Florida Research Foundation, Inc. Method for producing a mineral fiber
US7514249B2 (en) * 2002-04-18 2009-04-07 The University Of Florida Research Foundation, Inc. Biomimetic organic/inorganic composites
US7514248B2 (en) 2002-04-18 2009-04-07 University Of Florida Research Foundation, Inc. Process for making organic/inorganic composites
DE50311735D1 (de) * 2002-04-29 2009-09-03 Biomet Deutschland Gmbh Das tissue engineering von knochen
WO2004043338A2 (en) * 2002-05-10 2004-05-27 The Ohio State University Flavin n-oxides: new anti-cancer agents and pathogen eradication agents
US7166133B2 (en) 2002-06-13 2007-01-23 Kensey Nash Corporation Devices and methods for treating defects in the tissue of a living being
US6908591B2 (en) * 2002-07-18 2005-06-21 Clearant, Inc. Methods for sterilizing biological materials by irradiation over a temperature gradient
US20040013562A1 (en) * 2002-07-18 2004-01-22 Wilson Burgess Methods for sterilizing milk.
US20060147501A1 (en) * 2003-02-28 2006-07-06 Hillas Patrick J Collagen compositions and biomaterials
AU2004247143B2 (en) 2003-06-11 2010-09-23 Warsaw Orthopedic, Inc. Osteoimplants and methods for their manufacture
JP2005169008A (ja) * 2003-12-15 2005-06-30 Nipro Corp 生体適合性材料の滅菌方法
US20070190101A1 (en) * 2004-03-31 2007-08-16 Chunlin Yang Flowable bone grafts
US7678385B2 (en) * 2004-04-28 2010-03-16 Biomet Manufacturing Corp. Irradiated implantable bone material
US20050244450A1 (en) * 2004-04-28 2005-11-03 Reddi A H Heat-treated implantable bone material
WO2006083260A2 (en) 2004-04-28 2006-08-10 Angiotech Biomaterials Corporation Compositions and systems for forming crosslinked biomaterials and associated methods of preparation and use
US7722895B1 (en) 2004-09-20 2010-05-25 Warsaw Orthopedic, Inc. Osteogenic implants with combined implant materials, and materials and methods for same
US8506646B2 (en) * 2005-04-29 2013-08-13 Warsaw Orthopedic, Inc. Multi-purpose medical implant devices
US7857853B2 (en) * 2005-04-29 2010-12-28 Sdgi Holdings, Inc Synthetic loadbearing collagen-mineral composites useful for spinal implants, and methods of manufacture
DE202005009755U1 (de) * 2005-06-21 2005-09-08 Cervitech, Inc. Halter für Zwischenwirbelprothesen
US8920827B2 (en) * 2005-10-21 2014-12-30 Wake Forest University Health Sciences Keratin bioceramic compositions
WO2007056671A1 (en) * 2005-11-02 2007-05-18 Osteotech, Inc. Hemostatic bone graft
US8048857B2 (en) 2006-12-19 2011-11-01 Warsaw Orthopedic, Inc. Flowable carrier compositions and methods of use
US7718616B2 (en) 2006-12-21 2010-05-18 Zimmer Orthobiologics, Inc. Bone growth particles and osteoinductive composition thereof
US20120195938A1 (en) * 2007-05-30 2012-08-02 James Louis Rutkowski Formulations and methods for recovery from dental surgery
US9511076B2 (en) * 2008-05-30 2016-12-06 Clarion Research Group Formulations and methods for recovery from dental surgery
US9616153B2 (en) 2008-04-17 2017-04-11 Warsaw Orthopedic, Inc. Rigid bone graft substitute
US20090263507A1 (en) * 2008-04-18 2009-10-22 Warsaw Orthopedic, Inc. Biological markers and response to treatment for pain, inflammation, neuronal or vascular injury and methods of use
EP2358352B1 (en) * 2008-10-24 2018-08-29 Warsaw Orthopedic, Inc. Compositions and methods for promoting bone formation
US20130045923A1 (en) * 2009-08-28 2013-02-21 Tissue Science Laboratories Plc Collagenous material
CA3054722A1 (en) * 2010-07-08 2012-01-12 Lifecell Corporation Method for shaping tissue matrices
CN103313733A (zh) 2010-11-15 2013-09-18 捷迈整形外科生物材料有限公司 骨空隙填充剂
WO2012068376A2 (en) 2010-11-17 2012-05-24 Wake Forest University Health Sciences Keratin compositions for treatment of bone deficiency or injury
US10016528B2 (en) * 2013-09-09 2018-07-10 Eran Rosines Biologic prosthesis and methods of production and use
CZ307219B6 (cs) * 2015-10-09 2018-04-04 Ăšstav struktury a mechaniky hornin AVÄŚR, v.v.i. Biomateriál na bázi želatiny pro výrobu kostních náhrad a výplní a způsob jeho přípravy
EP3413943A1 (en) 2016-02-11 2018-12-19 LifeCell Corporation Methods for stabilizing collagen-containing tissue products against enzymatic degradation
US10058159B2 (en) 2016-12-01 2018-08-28 Richard L. Kronenthal Sterile compositions for human cosmetic products
CN111465418B (zh) 2017-12-14 2021-07-09 盖斯特里希医药公司 骨替代材料
IL275206B2 (en) 2017-12-14 2023-04-01 Geistlich Pharma Ag Dry implant composition and aqueous injection formulation of the implant
WO2020004646A1 (ja) * 2018-06-29 2020-01-02 国立研究開発法人量子科学技術研究開発機構 細胞培養用ハイドロゲル、ゲルキット、細胞培養物の製造方法、及び細胞培養用ハイドロゲルの製造方法
RO134200B1 (ro) 2018-11-23 2023-07-28 Institutul Naţional De Cercetare-Dezvoltare Textile Pielărie - Sucursala Institutul De Cercetare Pielărie Încălţăminte Procedeu de tratare şi piei conservate prin iradiere gama
KR102636183B1 (ko) 2019-06-14 2024-02-13 가이스틀리히 파마 아게 골 대체 물질의 콜라겐 기질 또는 그래뉼레이트 블렌드
CA3141985C (en) 2019-06-14 2023-12-05 Geistlich Pharma Ag Injectable aqueous implant formulation containing ascorbic acid

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3443261A (en) * 1967-09-01 1969-05-13 Fmc Corp Prosthetic structures from microcrystalline collagen
US3767437A (en) * 1971-10-20 1973-10-23 Avicon Inc Phosthetic structures derived from collagen
US3949073A (en) * 1974-11-18 1976-04-06 The Board Of Trustees Of Leland Stanford Junior University Process for augmenting connective mammalian tissue with in situ polymerizable native collagen solution
CH615099A5 (es) * 1975-08-07 1980-01-15 Ulf Sven Erik Rothman
CA1073360A (en) * 1975-10-22 1980-03-11 John R. Daniels Non-antigenic collagen and articles of manufacture
DE2843963A1 (de) * 1978-10-09 1980-04-24 Merck Patent Gmbh Im koerper resorbierbare geformte masse auf basis von kollagen und ihre verwendung in der medizin
US4349470A (en) * 1979-09-14 1982-09-14 Battista Orlando A Protein polymer hydrogels
EP0030583B1 (de) * 1979-12-18 1984-06-13 Oscobal Ag Knochenersatzmaterial und Verfahren zur Herstellung eines Knochenersatzmaterials
US4314380A (en) * 1980-09-26 1982-02-09 Koken Co., Ltd. Artificial bone
JPS5841A (ja) * 1981-06-22 1983-01-05 Matsushita Electric Ind Co Ltd パイプヒ−タ応用熱交換器
DE3124981A1 (de) * 1981-06-25 1983-01-13 Dr. Ruhland Nachfolger GmbH, 8425 Neustadt Wirkstoffhaltige kollageneinlage zum einfuehren in knochen oder weichteile und verfahren zu deren herstellung
JPS5858041A (ja) * 1981-10-05 1983-04-06 三菱鉱業セメント株式会社 骨欠損部及び空隙部充てん材
US4424208A (en) * 1982-01-11 1984-01-03 Collagen Corporation Collagen implant material and method for augmenting soft tissue
US4409332A (en) * 1982-01-12 1983-10-11 Jefferies Steven R Collagen-enzyme conjugates that exhibit no inflammatory response and method for making the same
US4582640A (en) * 1982-03-08 1986-04-15 Collagen Corporation Injectable cross-linked collagen implant material
EP0108661A1 (en) * 1982-10-04 1984-05-16 Merck & Co. Inc. Stabilized hydroxypropyl cellulose ophthalmic inserts and process to sterilize the same
DE3479402D1 (en) * 1984-06-12 1989-09-21 Oscobal Ag Method of producing a bone replacement material
US4789663A (en) * 1984-07-06 1988-12-06 Collagen Corporation Methods of bone repair using collagen
EP0169001A3 (en) * 1984-07-17 1987-11-25 Collagen Corporation Collagen coated bone implants
US4553974A (en) * 1984-08-14 1985-11-19 Mayo Foundation Treatment of collagenous tissue with glutaraldehyde and aminodiphosphonate calcification inhibitor
US4642117A (en) * 1985-03-22 1987-02-10 Collagen Corporation Mechanically sheared collagen implant material and method
CA1260391A (en) * 1985-03-28 1989-09-26 Karl A. Piez Xenogeneic collagen/mineral preparations in bone repair
US4992226A (en) * 1985-03-28 1991-02-12 Collagen Corporation Method of making molds with xenogeneic collagen/mineral preparations for bone repair
EP0246638A3 (en) * 1986-05-23 1989-03-15 Cordis Corporation Biologically modified synthetic grafts
US4865602A (en) * 1986-11-06 1989-09-12 Collagen Corporation Gamma irradiation of collagen/mineral mixtures

Also Published As

Publication number Publication date
EP0270254B1 (en) 1993-03-10
JPH0622571B2 (ja) 1994-03-30
US4865602A (en) 1989-09-12
AU603744B2 (en) 1990-11-22
AU8068087A (en) 1988-05-12
GR3007382T3 (es) 1993-07-30
US5035715A (en) 1991-07-30
JPS63132664A (ja) 1988-06-04
EP0270254A3 (en) 1990-03-07
CA1320451C (en) 1993-07-20
US5123925A (en) 1992-06-23
JPH062151B2 (ja) 1994-01-12
JPH05305133A (ja) 1993-11-19
EP0270254A2 (en) 1988-06-08

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