ES2052611T3 - Procedimiento mejorado de preparacion de celulas asesinas activadas. - Google Patents

Procedimiento mejorado de preparacion de celulas asesinas activadas.

Info

Publication number
ES2052611T3
ES2052611T3 ES88101138T ES88101138T ES2052611T3 ES 2052611 T3 ES2052611 T3 ES 2052611T3 ES 88101138 T ES88101138 T ES 88101138T ES 88101138 T ES88101138 T ES 88101138T ES 2052611 T3 ES2052611 T3 ES 2052611T3
Authority
ES
Spain
Prior art keywords
preparation
killer cells
improved procedure
activated killer
special
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES88101138T
Other languages
English (en)
Inventor
Joseph David Irr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Terumo Corp
Original Assignee
Terumo Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Terumo Corp filed Critical Terumo Corp
Application granted granted Critical
Publication of ES2052611T3 publication Critical patent/ES2052611T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0693—Tumour cells; Cancer cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0081—Purging biological preparations of unwanted cells
    • C12N5/0087—Purging against subsets of blood cells, e.g. purging alloreactive T cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/461—Cellular immunotherapy characterised by the cell type used
    • A61K39/4611—T-cells, e.g. tumor infiltrating lymphocytes [TIL], lymphokine-activated killer cells [LAK] or regulatory T cells [Treg]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
    • A61K39/4643—Vertebrate antigens
    • A61K39/4644—Cancer antigens
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0636—T lymphocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/02—Atmosphere, e.g. low oxygen conditions
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/30—Organic components
    • C12N2500/32—Amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/23—Interleukins [IL]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Mushroom Cultivation (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

LA INVENCION SE REFIERE A UN PROCESO MEJORADO PARA PREPARAR CELULAS MUERTAS ACTIVADAS CON LINFOQUINA O LINFOCITOS INFILTRANTES DE TUMORES, COMPRENDIENDO LA MEJORA EL CULTIVO DE CELULAS PRECURSORAS EN UN RECIPIENTE CERRADO HECHO DE UNA PELICULA DE UN MATERIAL COPOLIMERICO QUE TIEN UNA PERMEABILIDAD ESPECIFICADA AL OXIGENO, SELECCIONADO DE MATERIALES ESPECIFICADOS Y QUE TIENE UN ESPESOR COMPRENDIDO ENTRE 0,04 MM Y 0,23 MM.
ES88101138T 1987-01-29 1988-01-27 Procedimiento mejorado de preparacion de celulas asesinas activadas. Expired - Lifetime ES2052611T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US827387A 1987-01-29 1987-01-29

Publications (1)

Publication Number Publication Date
ES2052611T3 true ES2052611T3 (es) 1994-07-16

Family

ID=21730714

Family Applications (1)

Application Number Title Priority Date Filing Date
ES88101138T Expired - Lifetime ES2052611T3 (es) 1987-01-29 1988-01-27 Procedimiento mejorado de preparacion de celulas asesinas activadas.

Country Status (13)

Country Link
EP (1) EP0280054B1 (es)
JP (1) JPH06104060B2 (es)
KR (1) KR900004421B1 (es)
AT (1) ATE82319T1 (es)
AU (1) AU609768B2 (es)
CA (1) CA1300058C (es)
DE (1) DE3875752T2 (es)
DK (1) DK42188A (es)
ES (1) ES2052611T3 (es)
IE (1) IE880224L (es)
IL (1) IL85238A (es)
NZ (1) NZ223326A (es)
ZA (1) ZA88656B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8826298D0 (en) * 1988-11-10 1988-12-14 Williams N S Production of lak cells compositions containing them & their use in cancer therapy
DE69012105T2 (de) * 1989-02-21 1994-12-22 Terumo Corp Proliferation von cd4-lymfocyten.
CA2015294A1 (en) * 1989-04-28 1990-10-28 John J. Rinehart Generation and expansion of lak cells
US6190913B1 (en) * 1997-08-12 2001-02-20 Vijay Singh Method for culturing cells using wave-induced agitation
US7745209B2 (en) 2005-07-26 2010-06-29 Corning Incorporated Multilayered cell culture apparatus
US20080176318A1 (en) 2006-12-07 2008-07-24 Wilson John R Highly efficient devices and methods for culturing cells
DE102011106914B4 (de) 2011-07-08 2015-08-27 Zellwerk Gmbh Mäander- Bioreaktor und Verfahren zu dynamischen Expansion, Differenzierung und Ernte von hämatopoetischen Zellen

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4140162A (en) * 1977-07-28 1979-02-20 Baxter Travenol Lab Clear, autoclavable plastic formulation free of liquid plasticizers
US4280497A (en) * 1979-10-09 1981-07-28 Cutter Laboratories, Inc. Container for platelet storage
GB2065067B (en) * 1979-10-15 1983-06-22 Toppan Printing Co Ltd Laminated bags
US4496361A (en) * 1981-08-05 1985-01-29 E. I. Du Pont De Nemours And Company Platelet storage container
JPS5829465A (ja) * 1981-08-05 1983-02-21 イ−・アイ・デユ・ポン・ドウ・ヌム−ル・アンド・カンパニ− 血小板貯蔵容器
US4588401A (en) * 1982-06-29 1986-05-13 E. I. Du Pont De Nemours And Company Platelet storage container
JPS60160881A (ja) * 1984-01-03 1985-08-22 イ−・アイ・デユポン・ド・ネモア−ス・アンド・コンパニ− 細胞培養室のための薄いフイルム

Also Published As

Publication number Publication date
KR880009123A (ko) 1988-09-14
ATE82319T1 (de) 1992-11-15
EP0280054B1 (en) 1992-11-11
DK42188A (da) 1988-07-30
JPH06104060B2 (ja) 1994-12-21
AU1076188A (en) 1988-08-04
NZ223326A (en) 1989-10-27
IL85238A (en) 1992-03-29
AU609768B2 (en) 1991-05-09
JPS63202378A (ja) 1988-08-22
IL85238A0 (en) 1988-07-31
IE880224L (en) 1988-07-29
CA1300058C (en) 1992-05-05
DE3875752D1 (de) 1992-12-17
DE3875752T2 (de) 1993-04-22
DK42188D0 (da) 1988-01-28
EP0280054A1 (en) 1988-08-31
KR900004421B1 (ko) 1990-06-25
ZA88656B (en) 1989-09-27

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