IT8403511A0 - Procedimento per la preparazione di etofibrato o sostanze di pari osimili caratteristiche, inmicrogranuli-ritardo e prodotto ottenuto con tale procedimento - Google Patents
Procedimento per la preparazione di etofibrato o sostanze di pari osimili caratteristiche, inmicrogranuli-ritardo e prodotto ottenuto con tale procedimentoInfo
- Publication number
- IT8403511A0 IT8403511A0 IT8403511A IT351184A IT8403511A0 IT 8403511 A0 IT8403511 A0 IT 8403511A0 IT 8403511 A IT8403511 A IT 8403511A IT 351184 A IT351184 A IT 351184A IT 8403511 A0 IT8403511 A0 IT 8403511A0
- Authority
- IT
- Italy
- Prior art keywords
- procedure
- retay
- etofibrate
- microgranules
- substances
- Prior art date
Links
- XXRVYAFBUDSLJX-UHFFFAOYSA-N etofibrate Chemical compound C=1C=CN=CC=1C(=O)OCCOC(=O)C(C)(C)OC1=CC=C(Cl)C=C1 XXRVYAFBUDSLJX-UHFFFAOYSA-N 0.000 title 1
- 229960003501 etofibrate Drugs 0.000 title 1
- 239000000126 substance Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
Landscapes
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Magnetic Resonance Imaging Apparatus (AREA)
Priority Applications (9)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT03511/84A IT1180507B (it) | 1984-06-29 | 1984-06-29 | Procedimento per la preparazione di etofibrato o sostanze di pari o simili caratteristiche, in microgunuli-ritardo e prodotto ottenuto con tale procedimento |
EP85830154A EP0168360B1 (en) | 1984-06-29 | 1985-06-19 | Process for preparing etofibrate or similar compounds containing sustained release microgranules and products thus obtained |
AT85830154T ATE77052T1 (de) | 1984-06-29 | 1985-06-19 | Verfahren zur herstellung von etofibrat oder aehnliche verbindungen enthaltende mikrogranula mit verzoegerter freisetzung sowie die auf diese weise erhaltenen produkte. |
DE8585830154T DE3586185T2 (de) | 1984-06-29 | 1985-06-19 | Verfahren zur herstellung von etofibrat oder aehnliche verbindungen enthaltende mikrogranula mit verzoegerter freisetzung sowie die auf diese weise erhaltenen produkte. |
JP13707785A JPS6133113A (ja) | 1984-06-29 | 1985-06-25 | エトフイブレ−ト又は類似化合物含有遅延放出微小顆粒の製造方法及びその製品 |
ES544649A ES8701494A1 (es) | 1984-06-29 | 1985-06-27 | Procedimiento para la preparacion de etofibrato o compuestossimilares que contienen microgranulos de liberacion constan-te |
SU853917801A RU1829934C (ru) | 1984-06-29 | 1985-06-28 | Способ получени микрогранул этофибрата |
KR1019850004644A KR870001959B1 (ko) | 1984-06-29 | 1985-06-28 | 에토피브레이트 화합물을 함유하는 서방형 과립의 제조방법 |
US07/247,914 US4957746A (en) | 1984-06-29 | 1988-09-22 | Process for preparing etofibrate or similar compounds containing sustained release microgranules and products thus obtained |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT03511/84A IT1180507B (it) | 1984-06-29 | 1984-06-29 | Procedimento per la preparazione di etofibrato o sostanze di pari o simili caratteristiche, in microgunuli-ritardo e prodotto ottenuto con tale procedimento |
Publications (2)
Publication Number | Publication Date |
---|---|
IT8403511A0 true IT8403511A0 (it) | 1984-06-29 |
IT1180507B IT1180507B (it) | 1987-09-23 |
Family
ID=11108749
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT03511/84A IT1180507B (it) | 1984-06-29 | 1984-06-29 | Procedimento per la preparazione di etofibrato o sostanze di pari o simili caratteristiche, in microgunuli-ritardo e prodotto ottenuto con tale procedimento |
Country Status (9)
Country | Link |
---|---|
US (1) | US4957746A (it) |
EP (1) | EP0168360B1 (it) |
JP (1) | JPS6133113A (it) |
KR (1) | KR870001959B1 (it) |
AT (1) | ATE77052T1 (it) |
DE (1) | DE3586185T2 (it) |
ES (1) | ES8701494A1 (it) |
IT (1) | IT1180507B (it) |
RU (1) | RU1829934C (it) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4021678C2 (de) * | 1990-07-07 | 1994-07-07 | Merz & Co Gmbh & Co | Verfahren zur Herstellung klein dimensionierter Formkörper mit hohem Etofibrat-Gehalt und kontrollierter Wirkstoff-Freisetzung, deren Verwendung und daraus bestehende oral verabreichbare Applikationsformen |
SE9003296L (sv) * | 1990-10-16 | 1992-04-17 | Kabi Pharmacia Ab | Foerfarande foer att formulera laekemedel |
DE4317127A1 (de) * | 1993-05-19 | 1994-11-24 | Merz & Co Gmbh & Co | Verwendung von Etofibrat und pharmazeutische Zusammensetzungen, enthaltend Etofibrat, zur Behandlung der diabetischen Angio- und Retinopathie |
FR2758459B1 (fr) | 1997-01-17 | 1999-05-07 | Pharma Pass | Composition pharmaceutique de fenofibrate presentant une biodisponibilite elevee et son procede de preparation |
FR2758461A1 (fr) * | 1997-01-17 | 1998-07-24 | Pharma Pass | Composition pharmaceutique presentant une biodisponibilite elevee et son procede de preparation |
US6814977B1 (en) | 1998-12-18 | 2004-11-09 | Abbott Laboratories | Formulations comprising lipid-regulating agents |
US6838091B2 (en) | 1998-12-18 | 2005-01-04 | Abbott Laboratories | Formulations comprising lipid-regulating agents |
US7014864B1 (en) | 1998-12-18 | 2006-03-21 | Abbott Laboratories | Formulations comprising lipid-regulating agents |
US6368622B2 (en) | 1999-01-29 | 2002-04-09 | Abbott Laboratories | Process for preparing solid formulations of lipid regulating agents with enhanced dissolution and absorption |
US6719999B2 (en) | 1999-03-31 | 2004-04-13 | Abbott Laboratories | Formulations comprising lipid-regulating agents |
MXPA01012225A (es) * | 1999-05-28 | 2002-08-12 | Abbott Lab | Formulaciones novedosas que comprenden agentes reguladores de lipido. |
US6372251B2 (en) | 1999-06-11 | 2002-04-16 | Abbott Laboratories | Formulations comprising lipid-regulating agents |
FR2816507B1 (fr) * | 2000-11-16 | 2003-02-28 | Ethypharm Lab Prod Ethiques | Microgranules a base de principe actif, procede de fabrication et compositons pharmaceutiques integrant lesdits microgranules |
CN101961324A (zh) * | 2010-09-10 | 2011-02-02 | 武汉药谷生物工程有限公司 | 一种依托贝特缓释胶囊的处方及制备方法 |
CN102579366A (zh) * | 2012-03-23 | 2012-07-18 | 南京泽恒医药技术开发有限公司 | 一种依托贝特缓释微丸的制备方法 |
CN105769767A (zh) * | 2016-04-12 | 2016-07-20 | 武汉理工大学 | 依托贝特自乳化制剂及其制备方法 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4064230A (en) * | 1966-04-25 | 1977-12-20 | Schmid Laboratories, Inc. | Polyenic macrolide compositions |
US4000254A (en) * | 1966-04-25 | 1976-12-28 | Schmid Laboratories, Inc. | Fungimycin compositions |
US4321263A (en) * | 1980-09-30 | 1982-03-23 | Rowell Laboratories, Inc. | Psyllium compositions |
FR2494112B1 (it) * | 1980-11-19 | 1986-01-10 | Laruelle Claude | |
GB2115409B (en) * | 1982-02-24 | 1985-08-07 | Zyma Sa | Novel crystal modifications of (+)-catechin |
-
1984
- 1984-06-29 IT IT03511/84A patent/IT1180507B/it active
-
1985
- 1985-06-19 DE DE8585830154T patent/DE3586185T2/de not_active Expired - Fee Related
- 1985-06-19 AT AT85830154T patent/ATE77052T1/de not_active IP Right Cessation
- 1985-06-19 EP EP85830154A patent/EP0168360B1/en not_active Expired - Lifetime
- 1985-06-25 JP JP13707785A patent/JPS6133113A/ja active Pending
- 1985-06-27 ES ES544649A patent/ES8701494A1/es not_active Expired
- 1985-06-28 RU SU853917801A patent/RU1829934C/ru active
- 1985-06-28 KR KR1019850004644A patent/KR870001959B1/ko not_active IP Right Cessation
-
1988
- 1988-09-22 US US07/247,914 patent/US4957746A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
ATE77052T1 (de) | 1992-06-15 |
ES8701494A1 (es) | 1986-12-16 |
KR870001959B1 (ko) | 1987-10-23 |
JPS6133113A (ja) | 1986-02-17 |
US4957746A (en) | 1990-09-18 |
DE3586185D1 (de) | 1992-07-16 |
EP0168360B1 (en) | 1992-06-10 |
EP0168360A2 (en) | 1986-01-15 |
RU1829934C (ru) | 1993-07-23 |
EP0168360A3 (en) | 1987-01-07 |
IT1180507B (it) | 1987-09-23 |
DE3586185T2 (de) | 1993-01-21 |
KR860000069A (ko) | 1986-01-25 |
ES544649A0 (es) | 1986-12-16 |
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Legal Events
Date | Code | Title | Description |
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TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19970627 |