ES2052391T3 - Derivados de acido 5-aminosalicilico para la terapia de enfermedades inflamatorias cronicas del intestino. - Google Patents

Derivados de acido 5-aminosalicilico para la terapia de enfermedades inflamatorias cronicas del intestino.

Info

Publication number
ES2052391T3
ES2052391T3 ES91916335T ES91916335T ES2052391T3 ES 2052391 T3 ES2052391 T3 ES 2052391T3 ES 91916335 T ES91916335 T ES 91916335T ES 91916335 T ES91916335 T ES 91916335T ES 2052391 T3 ES2052391 T3 ES 2052391T3
Authority
ES
Spain
Prior art keywords
acid
derivatives
aminosalicilico
intestine
therapy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91916335T
Other languages
English (en)
Inventor
Roberto Pellicciari
Aaron Garzon
Carlo Clerici
Camillo Maria Francesc Palazzi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Depha Team SRL
Original Assignee
Depha Team SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Depha Team SRL filed Critical Depha Team SRL
Application granted granted Critical
Publication of ES2052391T3 publication Critical patent/ES2052391T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0205—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)3-C(=0)-, e.g. statine or derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

SE PRESENTAN DERIVADOS DEL ACIDO 5-AMINOSALICILICO ACILADOS EN EL GRUPO AMINO CON ACIDO GLUTAMICO O ASPARTICO Y/ O QUE TIENEN EL GRUPO DE CARBOXIDO INVOLUCRADO EN UN ENLACE PEPTIDO CON EL RESIDUO DE LEUCIL-PROLIL, LOS DERIVADOS SON UTILES COMO PRODROGAS DEL ACIDO 5-AMINOSALICILICO.
ES91916335T 1990-09-12 1991-09-10 Derivados de acido 5-aminosalicilico para la terapia de enfermedades inflamatorias cronicas del intestino. Expired - Lifetime ES2052391T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT02144390A IT1244873B (it) 1990-09-12 1990-09-12 Derivati dell'acido 5-aminosalicilico (5-asa) per la terapia delle infiammazioni croniche intestinali

Publications (1)

Publication Number Publication Date
ES2052391T3 true ES2052391T3 (es) 1994-07-01

Family

ID=11181864

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91916335T Expired - Lifetime ES2052391T3 (es) 1990-09-12 1991-09-10 Derivados de acido 5-aminosalicilico para la terapia de enfermedades inflamatorias cronicas del intestino.

Country Status (11)

Country Link
US (1) US5424292A (es)
EP (1) EP0548177B1 (es)
JP (1) JPH06500787A (es)
AT (1) ATE105841T1 (es)
AU (1) AU8530891A (es)
CA (1) CA2091459A1 (es)
DE (1) DE69102069T2 (es)
DK (1) DK0548177T3 (es)
ES (1) ES2052391T3 (es)
IT (1) IT1244873B (es)
WO (1) WO1992004369A1 (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5484605A (en) * 1988-11-25 1996-01-16 Henning Berlin Gmbh Chemie-Und Pharmawerk Agent for treating chronically inflammatory intestinal diseases
JP2002512625A (ja) * 1997-05-29 2002-04-23 メルク エンド カンパニー インコーポレーテッド 細胞接着阻害薬としての複素環アミド化合物
US6903075B1 (en) 1997-05-29 2005-06-07 Merck & Co., Inc. Heterocyclic amide compounds as cell adhesion inhibitors
US6716452B1 (en) * 2000-08-22 2004-04-06 New River Pharmaceuticals Inc. Active agent delivery systems and methods for protecting and administering active agents
US8394813B2 (en) 2000-11-14 2013-03-12 Shire Llc Active agent delivery systems and methods for protecting and administering active agents
US20060014697A1 (en) * 2001-08-22 2006-01-19 Travis Mickle Pharmaceutical compositions for prevention of overdose or abuse
US7169752B2 (en) * 2003-09-30 2007-01-30 New River Pharmaceuticals Inc. Compounds and compositions for prevention of overdose of oxycodone
NZ544162A (en) * 2003-05-29 2008-09-26 Shire Llc Abuse resistant amphetamine compounds

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7008623A (es) * 1969-06-25 1970-12-29
NL7008620A (es) * 1969-06-25 1970-12-29
JPS5569549A (en) * 1978-11-16 1980-05-26 Nitto Boseki Co Ltd Novel substrate for determination of enzyme activity
WO1981002672A1 (en) * 1980-03-20 1981-10-01 Ferring Farma Lab Pharmaceutical composition and method for the treatment of colitis ulcerosa and crohn's disease
US4505898A (en) * 1982-04-21 1985-03-19 Marks Robert E Derivatives of acetylsalicylic acid and substituted phenylacetic acids and compositions containing them
IT1196348B (it) * 1984-11-29 1988-11-16 Italfarmaco Spa Composti ad attivita'antiinfiammatoria
US5120306A (en) * 1990-03-21 1992-06-09 Gosselin Leon F Direct delivery of anti-inflammatories to the proximal small bowel

Also Published As

Publication number Publication date
AU8530891A (en) 1992-03-30
EP0548177A1 (en) 1993-06-30
US5424292A (en) 1995-06-13
CA2091459A1 (en) 1992-03-13
EP0548177B1 (en) 1994-05-18
JPH06500787A (ja) 1994-01-27
DK0548177T3 (da) 1994-08-22
ATE105841T1 (de) 1994-06-15
DE69102069D1 (de) 1994-06-23
DE69102069T2 (de) 1994-09-01
IT9021443A1 (it) 1992-03-12
IT9021443A0 (it) 1990-09-12
WO1992004369A1 (en) 1992-03-19
IT1244873B (it) 1994-09-12

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