DK0548177T3 - 5-Aminosalicylsyrederivater til terapi af kroniske inflammatoriske tarmsygdomme - Google Patents
5-Aminosalicylsyrederivater til terapi af kroniske inflammatoriske tarmsygdommeInfo
- Publication number
- DK0548177T3 DK0548177T3 DK91916335.2T DK91916335T DK0548177T3 DK 0548177 T3 DK0548177 T3 DK 0548177T3 DK 91916335 T DK91916335 T DK 91916335T DK 0548177 T3 DK0548177 T3 DK 0548177T3
- Authority
- DK
- Denmark
- Prior art keywords
- aminosalicylic acid
- acid derivatives
- pct
- therapy
- inflammatory bowel
- Prior art date
Links
- KBOPZPXVLCULAV-UHFFFAOYSA-N mesalamine Chemical class NC1=CC=C(O)C(C(O)=O)=C1 KBOPZPXVLCULAV-UHFFFAOYSA-N 0.000 title abstract 3
- 208000022559 Inflammatory bowel disease Diseases 0.000 title 1
- 230000001684 chronic effect Effects 0.000 title 1
- 238000002560 therapeutic procedure Methods 0.000 title 1
- OZDAOHVKBFBBMZ-UHFFFAOYSA-N 2-aminopentanedioic acid;hydrate Chemical compound O.OC(=O)C(N)CCC(O)=O OZDAOHVKBFBBMZ-UHFFFAOYSA-N 0.000 abstract 1
- WHUUTDBJXJRKMK-UHFFFAOYSA-N Glutamic acid Natural products OC(=O)C(N)CCC(O)=O WHUUTDBJXJRKMK-UHFFFAOYSA-N 0.000 abstract 1
- CKLJMWTZIZZHCS-REOHCLBHSA-N L-aspartic acid Chemical compound OC(=O)[C@@H](N)CC(O)=O CKLJMWTZIZZHCS-REOHCLBHSA-N 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 235000003704 aspartic acid Nutrition 0.000 abstract 1
- OQFSQFPPLPISGP-UHFFFAOYSA-N beta-carboxyaspartic acid Natural products OC(=O)C(N)C(C(O)=O)C(O)=O OQFSQFPPLPISGP-UHFFFAOYSA-N 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 235000013922 glutamic acid Nutrition 0.000 abstract 1
- 229960004963 mesalazine Drugs 0.000 abstract 1
- 229940002612 prodrug Drugs 0.000 abstract 1
- 239000000651 prodrug Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0205—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)3-C(=0)-, e.g. statine or derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Crystallography & Structural Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT02144390A IT1244873B (it) | 1990-09-12 | 1990-09-12 | Derivati dell'acido 5-aminosalicilico (5-asa) per la terapia delle infiammazioni croniche intestinali |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0548177T3 true DK0548177T3 (da) | 1994-08-22 |
Family
ID=11181864
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK91916335.2T DK0548177T3 (da) | 1990-09-12 | 1991-09-10 | 5-Aminosalicylsyrederivater til terapi af kroniske inflammatoriske tarmsygdomme |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US5424292A (da) |
| EP (1) | EP0548177B1 (da) |
| JP (1) | JPH06500787A (da) |
| AT (1) | ATE105841T1 (da) |
| AU (1) | AU8530891A (da) |
| CA (1) | CA2091459A1 (da) |
| DE (1) | DE69102069T2 (da) |
| DK (1) | DK0548177T3 (da) |
| ES (1) | ES2052391T3 (da) |
| IT (1) | IT1244873B (da) |
| WO (1) | WO1992004369A1 (da) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5484605A (en) * | 1988-11-25 | 1996-01-16 | Henning Berlin Gmbh Chemie-Und Pharmawerk | Agent for treating chronically inflammatory intestinal diseases |
| US6903075B1 (en) | 1997-05-29 | 2005-06-07 | Merck & Co., Inc. | Heterocyclic amide compounds as cell adhesion inhibitors |
| EP1001764A4 (en) * | 1997-05-29 | 2005-08-24 | Merck & Co Inc | Heterocyclic amides as cell adhesion inhibitors |
| US6716452B1 (en) * | 2000-08-22 | 2004-04-06 | New River Pharmaceuticals Inc. | Active agent delivery systems and methods for protecting and administering active agents |
| US8394813B2 (en) | 2000-11-14 | 2013-03-12 | Shire Llc | Active agent delivery systems and methods for protecting and administering active agents |
| US20060014697A1 (en) * | 2001-08-22 | 2006-01-19 | Travis Mickle | Pharmaceutical compositions for prevention of overdose or abuse |
| US7169752B2 (en) * | 2003-09-30 | 2007-01-30 | New River Pharmaceuticals Inc. | Compounds and compositions for prevention of overdose of oxycodone |
| BRPI0410792B8 (pt) * | 2003-05-29 | 2021-05-25 | New River Pharmaceuticals Inc | compostos de anfetamina resistentes à dependencia |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL7008623A (da) * | 1969-06-25 | 1970-12-29 | ||
| NL7008620A (da) * | 1969-06-25 | 1970-12-29 | ||
| JPS5569549A (en) * | 1978-11-16 | 1980-05-26 | Nitto Boseki Co Ltd | Novel substrate for determination of enzyme activity |
| WO1981002672A1 (en) * | 1980-03-20 | 1981-10-01 | Ferring Farma Lab | Pharmaceutical composition and method for the treatment of colitis ulcerosa and crohn's disease |
| US4505898A (en) * | 1982-04-21 | 1985-03-19 | Marks Robert E | Derivatives of acetylsalicylic acid and substituted phenylacetic acids and compositions containing them |
| IT1196348B (it) * | 1984-11-29 | 1988-11-16 | Italfarmaco Spa | Composti ad attivita'antiinfiammatoria |
| US5120306A (en) * | 1990-03-21 | 1992-06-09 | Gosselin Leon F | Direct delivery of anti-inflammatories to the proximal small bowel |
-
1990
- 1990-09-12 IT IT02144390A patent/IT1244873B/it active IP Right Grant
-
1991
- 1991-09-10 ES ES91916335T patent/ES2052391T3/es not_active Expired - Lifetime
- 1991-09-10 WO PCT/EP1991/001718 patent/WO1992004369A1/en active IP Right Grant
- 1991-09-10 EP EP91916335A patent/EP0548177B1/en not_active Expired - Lifetime
- 1991-09-10 DE DE69102069T patent/DE69102069T2/de not_active Expired - Fee Related
- 1991-09-10 AU AU85308/91A patent/AU8530891A/en not_active Abandoned
- 1991-09-10 AT AT91916335T patent/ATE105841T1/de not_active IP Right Cessation
- 1991-09-10 JP JP3515457A patent/JPH06500787A/ja active Pending
- 1991-09-10 DK DK91916335.2T patent/DK0548177T3/da active
- 1991-09-10 CA CA002091459A patent/CA2091459A1/en not_active Abandoned
- 1991-09-10 US US07/984,575 patent/US5424292A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| IT9021443A0 (it) | 1990-09-12 |
| EP0548177B1 (en) | 1994-05-18 |
| WO1992004369A1 (en) | 1992-03-19 |
| EP0548177A1 (en) | 1993-06-30 |
| AU8530891A (en) | 1992-03-30 |
| IT1244873B (it) | 1994-09-12 |
| ES2052391T3 (es) | 1994-07-01 |
| CA2091459A1 (en) | 1992-03-13 |
| US5424292A (en) | 1995-06-13 |
| IT9021443A1 (it) | 1992-03-12 |
| JPH06500787A (ja) | 1994-01-27 |
| DE69102069D1 (de) | 1994-06-23 |
| DE69102069T2 (de) | 1994-09-01 |
| ATE105841T1 (de) | 1994-06-15 |
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