ES2052370T3 - Peptidos o polipeptidos inmunologicamente activos del parvovirus b19. - Google Patents
Peptidos o polipeptidos inmunologicamente activos del parvovirus b19.Info
- Publication number
- ES2052370T3 ES2052370T3 ES91903270T ES91903270T ES2052370T3 ES 2052370 T3 ES2052370 T3 ES 2052370T3 ES 91903270 T ES91903270 T ES 91903270T ES 91903270 T ES91903270 T ES 91903270T ES 2052370 T3 ES2052370 T3 ES 2052370T3
- Authority
- ES
- Spain
- Prior art keywords
- gene
- parvovirus
- antigens
- polypeptides
- immunologically active
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/14011—Parvoviridae
- C12N2750/14211—Erythrovirus, e.g. B19 virus
- C12N2750/14222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Gastroenterology & Hepatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
SE OBTIENEN PEPTIDOS O POLIPEPTIDOS ACTIVOS INMUNOLOGICAMENTE CON UN SECUENCIA DE AMINOACIDO PARCIAL DE LAS CAPSIDOPROTEINAS VP1 Y VP2 DEL PARVOVIRUS B19, QUE PERMITEN UNA REALIZACION DE PRUEBAS ECONOMICA, SENSITIVA Y ESPECIFICA PARA LA DETERMINACION DE LOS ANTICUERPOS CONTRA EL PARVOVIRUS HUMANO B19. SE IDENTIFICAN SECUENCIAS CORTAS DE PEPTIDOS QUE APLICADAS COMO ANTIGENO SIRVEN PARA LA IDENTIFICACION DE LOS SUEROS ANTI-B19-IGG POSITIVOS. ADEMAS, SE DESCRIBE LA PRODUCCION DE ESTOS PEPTIDOS CON MEDIDAS DE INGENIERIA GENETICA. OTROS ANTIGENOS PRODUCIDOS GENETICAMENTE, QUE SE PUEDEN OBTENER ESTABLES CON UN MAYOR RENDIMIENTO EN E. COLI Y QUE SE PUEDEN DEPURAR A PARTIR DE ESTOS A CONTINUACION, SIRVEN COMO ANTIGENOS ADICIONALES PARA LA PRUEBA DE LA IGG. FINALMENTE, UN CONJUNTO DE ANTIGENOS PERMITE LAS REALIZACIONES DE PRUEBAS PARA LA DETERMINACION DE LOS ANTICUERPOS IGM CONTRA EL VIRUS. ADICIONALMENTE, LOS COMPONENTES GENERADOS GENETICAMENTE DE LA PROTEINA SUPERFICIAL REPRESENTAN SUSTANCIAS QUESE PUEDEN UTILIZAR PARA UNA INMUNIZACION PROFILACTICA.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE4003826A DE4003826C2 (de) | 1990-02-08 | 1990-02-08 | Peptide der Kapsidproteine VP1 oder VP2 des Parvovirus B19 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2052370T3 true ES2052370T3 (es) | 1994-07-01 |
Family
ID=6399718
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES91903270T Expired - Lifetime ES2052370T3 (es) | 1990-02-08 | 1991-02-08 | Peptidos o polipeptidos inmunologicamente activos del parvovirus b19. |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP0514413B1 (es) |
JP (2) | JP3061196B2 (es) |
AT (1) | ATE105303T1 (es) |
AU (1) | AU650864B2 (es) |
CA (1) | CA2075366C (es) |
DE (2) | DE4003826C2 (es) |
DK (1) | DK0514413T3 (es) |
ES (1) | ES2052370T3 (es) |
WO (1) | WO1991012269A1 (es) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP3149116B2 (ja) * | 1992-10-28 | 2001-03-26 | 信越化学工業株式会社 | ヒトパルボウイルスのエピトープ関連ペプチド |
US5785974A (en) * | 1993-01-23 | 1998-07-28 | Immunologia Y Genetica Aplicada, S.A. | Synthetic peptides and vaccines against parvovirus |
WO1995011997A1 (en) * | 1993-10-28 | 1995-05-04 | Deutsches Krebsforschungszentrum, Stiftung Des Öffentlichen Rechts | Adeno-associated virus - its diagnostic use with early abortion |
WO1996027799A1 (en) * | 1995-03-08 | 1996-09-12 | Klaus Hedman | Method for the diagnosis of infections |
JPH0910000A (ja) | 1995-06-26 | 1997-01-14 | Nippon Sekijiyuujishiya | ヒトパルボウイルスの検出方法及びそのための試薬 |
FR2771751B1 (fr) * | 1997-12-03 | 2000-05-26 | Assist Publ Hopitaux De Paris | Erythrovirus et ses applications |
US6238860B1 (en) | 1998-11-05 | 2001-05-29 | Dyax Corp. | Binding moieties for human parvovirus B19 |
US6743772B1 (en) | 1998-11-24 | 2004-06-01 | Kristina Broliden | Use of parovirus capsid particles in the inhibition of cell proliferation and migration |
US6818612B2 (en) | 1998-11-24 | 2004-11-16 | Kristina Broliden | Use of parvovirus capsid particles in the inhibition of cell proliferation and migration |
KR100888377B1 (ko) | 2001-06-28 | 2009-03-13 | 노바티스 백신즈 앤드 다이아그노스틱스 인코포레이티드 | 파르보바이러스 b19의 진단 분석 |
US7094541B2 (en) | 2001-08-31 | 2006-08-22 | Gen-Probe Incorporated | Assay for detection of human parvovirus B19 nucleic acid |
WO2007096199A2 (en) * | 2006-02-22 | 2007-08-30 | Ikdt Institut Kardiale Diagnostik Und Therapie Gmbh | Differential diagnostics and therapy of virally induced heart muscle disease |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0322417A1 (en) * | 1986-09-08 | 1989-07-05 | Applied Biotechnology, Inc. | Empty viral capsid vaccines |
DE3939470A1 (de) * | 1989-11-29 | 1991-06-06 | Biochrom Beteiligungs Gmbh & C | Peptide und antikoerper gegen peptide, welche zur diagnose und zur verhuetung der b19-infektion verwendbar sind |
-
1990
- 1990-02-08 DE DE4003826A patent/DE4003826C2/de not_active Expired - Fee Related
-
1991
- 1991-02-08 EP EP91903270A patent/EP0514413B1/de not_active Expired - Lifetime
- 1991-02-08 DE DE59101577T patent/DE59101577D1/de not_active Expired - Lifetime
- 1991-02-08 WO PCT/DE1991/000106 patent/WO1991012269A1/de active IP Right Grant
- 1991-02-08 CA CA002075366A patent/CA2075366C/en not_active Expired - Lifetime
- 1991-02-08 AU AU72115/91A patent/AU650864B2/en not_active Expired
- 1991-02-08 JP JP3503659A patent/JP3061196B2/ja not_active Expired - Lifetime
- 1991-02-08 ES ES91903270T patent/ES2052370T3/es not_active Expired - Lifetime
- 1991-02-08 DK DK91903270.6T patent/DK0514413T3/da active
- 1991-02-08 AT AT9191903270T patent/ATE105303T1/de not_active IP Right Cessation
-
2000
- 2000-01-24 JP JP2000017931A patent/JP3130024B2/ja not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP0514413A1 (de) | 1992-11-25 |
DE4003826C2 (de) | 1995-11-23 |
JP3130024B2 (ja) | 2001-01-31 |
WO1991012269A1 (de) | 1991-08-22 |
JP2000184889A (ja) | 2000-07-04 |
CA2075366C (en) | 2003-02-18 |
EP0514413B1 (de) | 1994-05-04 |
JP3061196B2 (ja) | 2000-07-10 |
DK0514413T3 (da) | 1994-06-06 |
DE4003826A1 (de) | 1991-08-14 |
AU650864B2 (en) | 1994-07-07 |
ATE105303T1 (de) | 1994-05-15 |
DE59101577D1 (de) | 1994-06-09 |
AU7211591A (en) | 1991-09-03 |
CA2075366A1 (en) | 1991-08-09 |
JPH05504143A (ja) | 1993-07-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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