ES2047171T3 - Sistema terapeutico para la administracion transdermica o transmucosa de sustancias activas, asi como su aplicacion. - Google Patents

Sistema terapeutico para la administracion transdermica o transmucosa de sustancias activas, asi como su aplicacion.

Info

Publication number
ES2047171T3
ES2047171T3 ES90102174T ES90102174T ES2047171T3 ES 2047171 T3 ES2047171 T3 ES 2047171T3 ES 90102174 T ES90102174 T ES 90102174T ES 90102174 T ES90102174 T ES 90102174T ES 2047171 T3 ES2047171 T3 ES 2047171T3
Authority
ES
Spain
Prior art keywords
reservoir
another
parts
therapeutic system
layer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90102174T
Other languages
English (en)
Inventor
Walter Dr Dipl-Chem Muller
Michael Roreger
Heinrich Kindel
Peter Bohnenkamper
Heike Palm
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LTS Lohmann Therapie Systeme AG
Original Assignee
LTS Lohmann Therapie Systeme AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by LTS Lohmann Therapie Systeme AG filed Critical LTS Lohmann Therapie Systeme AG
Application granted granted Critical
Publication of ES2047171T3 publication Critical patent/ES2047171T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7092—Transdermal patches having multiple drug layers or reservoirs, e.g. for obtaining a specific release pattern, or for combining different drugs

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Polyesters Or Polycarbonates (AREA)

Abstract

EL INVENTO SE REFIERE A UN SISTEMA TERAPEUTICO PARA SUMINISTRAR AGENTES TRANSDERMALES O TRANSMUCOSOS DE UNA CAPA POSTERIOR IMPERMEABLE, UN RESERVORIO QUE CONTIENE POR LO MENOS PARCIALMENTE LOS AGENTES Y QUE SE COMPONE DE DOS CAPAS DE PARTE SEPARADAS ENTRE SI DE UNA CAPA PROTECTORA, SIENDO LAS DOS PARTES DEL RESERVORIO (A) COLOCADAS UNA ENCIMA DE LA OTRA EN SU MAYOR PARTE PARALELAMENTE (B) SEPARADAS POR UNA CAPA INTERMEDIA E IMPERMEABLE PARA LOS CONTENIDOS DE AMBAS PARTES DEL RESERVORIO Y QUE SE PUEDE QUITAR (C) Y TENIENDO AMBAS PARTES DEL RESERVORIO O BIEN AGENTES, AGENTES AUXILIARES O AMBOS EN CONCENTRACIONES QUE NO CORRESPONDEN AL EQUILIBRIO DE REPARTO SIENDO PEGADOS DE FORMA AUTOADHESIVA Y PARCIALMENTE MEDIANTE UNA MASCARA AMBAS PARTES DEL RESERVORIO. LA CAPA INTERMEDIA (B) SE ENCUENTRA ENTRE UNA PARTE DEL RESERVORIO Y LA MASCARA Y ESTA FORMADA POR LAMINAS PLEGADAS QUE TRANSMITEN LAS SUPERFICIES DE LAS PARTES DEL RESERVORIO POR LO MENOS PARCIALMENTE.
ES90102174T 1989-02-09 1990-02-03 Sistema terapeutico para la administracion transdermica o transmucosa de sustancias activas, asi como su aplicacion. Expired - Lifetime ES2047171T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3903794A DE3903794A1 (de) 1989-02-09 1989-02-09 Therapeutisches system zur transdermalen oder transmucosalen verabreichung von wirkstoffen und seine verwendung

Publications (1)

Publication Number Publication Date
ES2047171T3 true ES2047171T3 (es) 1994-02-16

Family

ID=6373693

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90102174T Expired - Lifetime ES2047171T3 (es) 1989-02-09 1990-02-03 Sistema terapeutico para la administracion transdermica o transmucosa de sustancias activas, asi como su aplicacion.

Country Status (12)

Country Link
US (1) US5128137A (es)
EP (1) EP0382129B1 (es)
JP (1) JP2538371B2 (es)
AT (1) ATE95711T1 (es)
CA (1) CA2009558C (es)
DD (1) DD291700A5 (es)
DE (2) DE3903794A1 (es)
DK (1) DK0382129T3 (es)
ES (1) ES2047171T3 (es)
FI (1) FI105156B (es)
IE (1) IE64835B1 (es)
NO (1) NO180670C (es)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUT65957A (en) † 1992-03-17 1994-08-29 Becton Dickinson Co User operated iontophoretical device and method for manufacturing it
JP2542792B2 (ja) * 1992-11-05 1996-10-09 ベクトン・ディッキンソン・アンド・カンパニー ユ―ザ作動型のイオン導入式装置
US5445609A (en) * 1993-05-28 1995-08-29 Alza Corporation Electrotransport agent delivery device having a disposable component and a removable liner
US5962011A (en) * 1993-12-06 1999-10-05 Schering-Plough Healthcare Products, Inc. Device for delivery of dermatological ingredients
FR2728463A1 (fr) * 1994-12-21 1996-06-28 Lhd Lab Hygiene Dietetique Systeme transdermique d'administration simultanee de plusieurs principes actifs
US5658583A (en) * 1995-07-28 1997-08-19 Zhang; Jie Apparatus and methods for improved noninvasive dermal administration of pharmaceuticals
US6284266B1 (en) 1995-07-28 2001-09-04 Zars, Inc. Methods and apparatus for improved administration of fentanyl and sufentanil
US6245347B1 (en) 1995-07-28 2001-06-12 Zars, Inc. Methods and apparatus for improved administration of pharmaceutically active compounds
US20040265353A1 (en) * 1995-07-28 2004-12-30 Zars, Inc. Systems and methods for treating panic attacks
GB9515807D0 (en) * 1995-08-02 1995-10-04 Cantwell Evelyna D Topical hyperbaric bandage
DE29514849U1 (de) * 1995-09-15 1995-11-16 Weyergans, Rudolf, 52355 Düren Cellulitis-Pflaster
US5797867A (en) * 1996-09-27 1998-08-25 Becton Dickinson And Company Iontophoretic drug delivery system, including method for activating same for attachment to patient
US5738647A (en) * 1996-09-27 1998-04-14 Becton Dickinson And Company User activated iontophoretic device and method for activating same
US6955819B2 (en) 1998-09-29 2005-10-18 Zars, Inc. Methods and apparatus for using controlled heat to regulate transdermal and controlled release delivery of fentanyl, other analgesics, and other medical substances
US6726673B1 (en) 1999-05-24 2004-04-27 Zars, Inc. Methods and apparatus for improved administration of testosterone pharmaceuticals
US6453648B1 (en) 1999-07-06 2002-09-24 Zars, Inc. Method for manufacturing a heat generating apparatus
US6261595B1 (en) 2000-02-29 2001-07-17 Zars, Inc. Transdermal drug patch with attached pocket for controlled heating device
EP1284644B1 (en) * 2000-05-29 2004-10-20 Medicotest A/S An electrode for establishing electrical contact with the skin
US6767342B1 (en) 2001-04-23 2004-07-27 Evelyna D. Cantwell Oxygen bandage system
US8524272B2 (en) 2003-08-15 2013-09-03 Mylan Technologies, Inc. Transdermal patch incorporating active agent migration barrier layer
DE102004020463A1 (de) † 2004-04-26 2005-11-10 Grünenthal GmbH Wirkstoffabgabesystem aus einem wirkstoffhaltigen Pflaster und mindestens einem Wirkstoffabgaberegulierungsmittel
US20060099247A1 (en) * 2004-11-10 2006-05-11 Byrd-Walsh, Llc. Liquid, gas and/or vapor phase delivery systems
DE102004062614B4 (de) * 2004-12-24 2011-12-29 Lts Lohmann Therapie-Systeme Ag Transdermales therapeutisches System mit aktivierbarer Übersättigung und kontrollierter Permeationförderung sowie Verfahren zu dessen Herstellung
US7955677B2 (en) 2005-12-07 2011-06-07 Mylan Technologies, Inc. Two-sided non-stick release film
DE102007016684A1 (de) * 2007-04-04 2008-10-09 Dr. Schumacher Gmbh Biologisch abbaubares Mehrschichtsystem
US20090304776A1 (en) * 2008-06-06 2009-12-10 Totada Shantha Transmucosal delivery of therapeutic agents and methods of use thereof
CN102202728A (zh) * 2008-09-05 2011-09-28 特拉旺蒂药物股份有限公司 电离子透入药物传送组装结构
US9012477B2 (en) * 2009-01-06 2015-04-21 Nuvo Research Inc. Method of treating neuropathic pain
CA2757302A1 (en) * 2009-04-01 2010-10-07 Andrew Crockett Methods for treating myofascial, muscle, and/or back pain
US9186334B2 (en) 2009-05-04 2015-11-17 Nuvo Research Inc. Heat assisted lidocaine and tetracaine for transdermal analgesia
AU2010246064A1 (en) * 2009-05-04 2011-12-22 Zars Pharma, Inc. Methods of treating pains associated with neuroma, nerve entrapment, and other conditions
AU2011205730C1 (en) 2010-01-14 2014-10-09 Nuvo Research Inc. Solid-forming local anesthetic formulations for pain control
GB201019761D0 (en) * 2010-11-22 2011-01-05 Chowdhury Dewan F H Multilayered transdermal patch
CN103228318B (zh) 2010-11-23 2016-03-23 泰华制药国际有限公司 使用者激活的自包含共封装的离子透入给药系统
US8696637B2 (en) * 2011-02-28 2014-04-15 Kimberly-Clark Worldwide Transdermal patch containing microneedles
WO2014124945A1 (de) * 2013-02-12 2014-08-21 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Silikonbeschichtete trennfolien mit besonderer vakuumtiefziehfähigkeit

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1071897B (es) * 1957-12-19 1959-12-24
FR2562800A1 (fr) * 1984-04-11 1985-10-18 Fournier Laboratoires Dispositif pour l'administration percutanee de medicaments
US4627429A (en) * 1986-02-28 1986-12-09 American Home Products Corporation Storage-stable transdermal adhesive patch
EP0249475A3 (en) * 1986-06-13 1989-10-11 Alza Corporation Delayed percutaneous delivery
US4906169A (en) * 1986-12-29 1990-03-06 Rutgers, The State University Of New Jersey Transdermal estrogen/progestin dosage unit, system and process
US5023084A (en) * 1986-12-29 1991-06-11 Rutgers, The State University Of New Jersey Transdermal estrogen/progestin dosage unit, system and process
US5000956A (en) * 1987-03-09 1991-03-19 Alza Corporation Prevention of contact allergy by coadministration of a corticosteroid with a sensitizing drug
US4764379A (en) * 1987-08-24 1988-08-16 Alza Corporation Transdermal drug delivery device with dual permeation enhancers
US4885154A (en) * 1988-03-01 1989-12-05 Alza Corporation Method for reducing sensitization or irritation in transdermal drug delivery and means therefor

Also Published As

Publication number Publication date
IE900451L (en) 1990-08-09
FI105156B (fi) 2000-06-30
NO180670B (no) 1997-02-17
DE59003039D1 (de) 1993-11-18
JP2538371B2 (ja) 1996-09-25
US5128137A (en) 1992-07-07
CA2009558C (en) 1996-08-06
NO900604D0 (no) 1990-02-08
IE64835B1 (en) 1995-09-06
JPH02264715A (ja) 1990-10-29
DE3903794C2 (es) 1992-07-16
DE3903794A1 (de) 1990-08-16
ATE95711T1 (de) 1993-10-15
NO180670C (no) 1997-05-28
EP0382129A2 (de) 1990-08-16
DK0382129T3 (da) 1994-02-14
EP0382129B1 (de) 1993-10-13
NO900604L (no) 1990-08-10
FI900622A0 (fi) 1990-02-08
CA2009558A1 (en) 1990-08-09
DD291700A5 (de) 1991-07-11
EP0382129A3 (de) 1991-02-27

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