ES2039239T3 - Vacuna contra el virus varicela-zoster. - Google Patents
Vacuna contra el virus varicela-zoster.Info
- Publication number
- ES2039239T3 ES2039239T3 ES87303561T ES87303561T ES2039239T3 ES 2039239 T3 ES2039239 T3 ES 2039239T3 ES 87303561 T ES87303561 T ES 87303561T ES 87303561 T ES87303561 T ES 87303561T ES 2039239 T3 ES2039239 T3 ES 2039239T3
- Authority
- ES
- Spain
- Prior art keywords
- vaccine
- glycoprotein
- sequence
- zoster
- varicela
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 229960005486 vaccine Drugs 0.000 title abstract 3
- 208000007514 Herpes zoster Diseases 0.000 title abstract 2
- 102000003886 Glycoproteins Human genes 0.000 abstract 3
- 108090000288 Glycoproteins Proteins 0.000 abstract 3
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 3
- 241000700605 Viruses Species 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 230000002163 immunogen Effects 0.000 abstract 1
- 230000003472 neutralizing effect Effects 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16711—Varicellovirus, e.g. human herpesvirus 3, Varicella Zoster, pseudorabies
- C12N2710/16722—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Communicable Diseases (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Saccharide Compounds (AREA)
Abstract
SE HA IDENTIFICADO POR ANALISIS DE LAS SECUENCIAS ADN UN GEN DE VIRUS DE VARICELLA-ZOSTER (VVZ) QUE CODIFICA PROTEINAS VIRICAS EN LA SUPERFICIE EXTERIOR INMUNOGENICA. LOS ANTICUERPOS DIRIGIDOS CONTRA PEPTIDOS FORMADOS A PARTIR DE LA SECUENCIA DE ADN PUEDEN REACCIONAR CON LA GLICOPROTEINA, QUE A SU VEZ ES REACTIVA CON ANTICUERPOS NEUTRALIZANTES. LA SECUENCIA AMINOTERMINAL DE LA GLICOPROTEINA ES IDENTICA A UNA PORCION DE LA SECUENCIA DE AMINOACIDOS FORMADOS A PARTIR DE LA SECUENCIA DE ADN. ESTA GLICOPROTEINA ES UTIL PARA LA PREPARACION DE UNA VACUNA CONTRA EL VIRUS VVZ.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/859,159 US4952674A (en) | 1986-05-02 | 1986-05-02 | Vaccine against varicella-zoster virus |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2039239T3 true ES2039239T3 (es) | 1995-04-01 |
Family
ID=25330208
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES87303561T Expired - Lifetime ES2039239T3 (es) | 1986-05-02 | 1987-04-23 | Vacuna contra el virus varicela-zoster. |
Country Status (8)
Country | Link |
---|---|
US (2) | US4952674A (es) |
EP (1) | EP0244155B1 (es) |
JP (1) | JP2530847B2 (es) |
AT (1) | ATE73495T1 (es) |
DE (1) | DE3777233D1 (es) |
DK (1) | DK222587A (es) |
ES (1) | ES2039239T3 (es) |
IE (1) | IE59791B1 (es) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0405867B1 (en) * | 1989-06-27 | 1995-03-15 | SMITHKLINE BEECHAM BIOLOGICALS s.a. | Novel compounds |
US5434074A (en) * | 1991-07-05 | 1995-07-18 | Gibson; D. Wade | Cytomegalovirus proteinase |
US6406902B1 (en) | 1991-07-05 | 2002-06-18 | Johns Hopkins University | Herpes virus proteinase and methods of assaying |
ES2165367T5 (es) | 1992-07-17 | 2009-08-05 | MERCK & CO., INC. | Procedimiento para prevenir el herpes zoster o para aliviar la neuralgia post-herpetica relacionada con la varicela. |
CA2177060A1 (en) * | 1993-12-21 | 1995-06-29 | Philip J. Provost | Thermostable varicella zoster virus |
AU2361495A (en) | 1994-04-28 | 1995-11-29 | Aviron | A novel vzv gene, mutant vzv and immunogenic compositions |
KR100374308B1 (ko) * | 1995-07-27 | 2003-12-18 | 주식회사 엘지생명과학 | 재조합차이니스햄스터오바리세포로부터발현된수두바이러스의지피i당단백질의정제방법 |
US6313127B1 (en) | 1996-02-02 | 2001-11-06 | Zeneca Limited | Heterocyclic compounds useful as pharmaceutical agents |
DE69738597T2 (de) * | 1996-02-09 | 2008-07-24 | Glaxosmithkline Biologicals S.A. | Vakzine gegen das varicella zostervirus produkt von gen 63 |
US7112331B2 (en) | 1996-02-09 | 2006-09-26 | Smithkline Beecham Biologicals, S.A. | Vaccines against varicella zoster virus gene 63 product |
US5710248A (en) | 1996-07-29 | 1998-01-20 | University Of Iowa Research Foundation | Peptide tag for immunodetection and immunopurification |
US6210683B1 (en) | 1997-09-05 | 2001-04-03 | Merck & Co., Inc. | Stabilizers containing recombinant human serum albumin for live virus vaccines |
EP2670443A4 (en) * | 2011-01-31 | 2015-10-14 | Univ Pennsylvania | NUCLEIC ACID MOLECULES ENCODING NEW HERPES ANTIGENS, VACCINE COMPRISING THE SAME, AND METHODS OF USING SAME |
JP2023516629A (ja) * | 2020-02-28 | 2023-04-20 | セルトリオン, インク. | 水痘帯状疱疹ウイルス融合タンパク質およびこれを含む免疫原性組成物 |
CN114081943B (zh) * | 2021-11-08 | 2024-04-02 | 中国医学科学院医学生物学研究所 | 一种水痘-带状疱疹mRNA疫苗组合物及其制备方法和应用 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0211756A1 (en) * | 1985-08-01 | 1987-02-25 | Merck & Co. Inc. | Assay for varicella-zoster virus (VZV) antibodies |
US4686101A (en) * | 1985-08-02 | 1987-08-11 | Merck & Co., Inc. | Vaccine against varicella-zoster virus |
US4665159A (en) * | 1985-11-07 | 1987-05-12 | Miles Laboratories, Inc. | High titer varicella-zoster immune globulin for intravenous administration |
-
1986
- 1986-05-02 US US06/859,159 patent/US4952674A/en not_active Expired - Lifetime
-
1987
- 1987-04-23 DE DE8787303561T patent/DE3777233D1/de not_active Expired - Fee Related
- 1987-04-23 AT AT87303561T patent/ATE73495T1/de active
- 1987-04-23 ES ES87303561T patent/ES2039239T3/es not_active Expired - Lifetime
- 1987-04-23 EP EP87303561A patent/EP0244155B1/en not_active Expired - Lifetime
- 1987-05-01 JP JP62108777A patent/JP2530847B2/ja not_active Expired - Lifetime
- 1987-05-01 DK DK222587A patent/DK222587A/da not_active Application Discontinuation
- 1987-05-11 IE IE116987A patent/IE59791B1/en not_active IP Right Cessation
-
1992
- 1992-06-09 US US07/896,038 patent/US5306635A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
JP2530847B2 (ja) | 1996-09-04 |
EP0244155B1 (en) | 1992-03-11 |
IE871169L (en) | 1987-11-02 |
EP0244155A1 (en) | 1987-11-04 |
DK222587A (da) | 1987-11-03 |
US4952674A (en) | 1990-08-28 |
US5306635A (en) | 1994-04-26 |
IE59791B1 (en) | 1994-04-06 |
DK222587D0 (da) | 1987-05-01 |
JPS62285792A (ja) | 1987-12-11 |
DE3777233D1 (de) | 1992-04-16 |
ATE73495T1 (de) | 1992-03-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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