ATE73495T1 - Impfstoff gegen varicella-zoster-virus. - Google Patents

Impfstoff gegen varicella-zoster-virus.

Info

Publication number
ATE73495T1
ATE73495T1 AT87303561T AT87303561T ATE73495T1 AT E73495 T1 ATE73495 T1 AT E73495T1 AT 87303561 T AT87303561 T AT 87303561T AT 87303561 T AT87303561 T AT 87303561T AT E73495 T1 ATE73495 T1 AT E73495T1
Authority
AT
Austria
Prior art keywords
zoster virus
vaccine against
glycoprotein
dna sequence
varicella zoster
Prior art date
Application number
AT87303561T
Other languages
English (en)
Inventor
Paul M Keller
Ronald W Ellis
Robert S Lowe
Mark W Riemen
Andrew J Davison
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Application granted granted Critical
Publication of ATE73495T1 publication Critical patent/ATE73495T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16711—Varicellovirus, e.g. human herpesvirus 3, Varicella Zoster, pseudorabies
    • C12N2710/16722—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
AT87303561T 1986-05-02 1987-04-23 Impfstoff gegen varicella-zoster-virus. ATE73495T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/859,159 US4952674A (en) 1986-05-02 1986-05-02 Vaccine against varicella-zoster virus
EP87303561A EP0244155B1 (de) 1986-05-02 1987-04-23 Impfstoff gegen Varicella-Zoster-Virus

Publications (1)

Publication Number Publication Date
ATE73495T1 true ATE73495T1 (de) 1992-03-15

Family

ID=25330208

Family Applications (1)

Application Number Title Priority Date Filing Date
AT87303561T ATE73495T1 (de) 1986-05-02 1987-04-23 Impfstoff gegen varicella-zoster-virus.

Country Status (8)

Country Link
US (2) US4952674A (de)
EP (1) EP0244155B1 (de)
JP (1) JP2530847B2 (de)
AT (1) ATE73495T1 (de)
DE (1) DE3777233D1 (de)
DK (1) DK222587A (de)
ES (1) ES2039239T3 (de)
IE (1) IE59791B1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CY1933A (en) * 1989-06-27 1990-06-22 Smithkline Biolog Novel compounds
US5434074A (en) * 1991-07-05 1995-07-18 Gibson; D. Wade Cytomegalovirus proteinase
US6406902B1 (en) 1991-07-05 2002-06-18 Johns Hopkins University Herpes virus proteinase and methods of assaying
ES2165367T5 (es) * 1992-07-17 2009-08-05 MERCK & CO., INC. Procedimiento para prevenir el herpes zoster o para aliviar la neuralgia post-herpetica relacionada con la varicela.
JPH09506777A (ja) * 1993-12-21 1997-07-08 メルク エンド カンパニー インコーポレーテッド 熱安定性の水痘帯状疱疹ウイルス
WO1995029991A1 (en) * 1994-04-28 1995-11-09 Aviron A novel vzv gene, mutant vzv and immunogenic compositions
KR100374308B1 (ko) * 1995-07-27 2003-12-18 주식회사 엘지생명과학 재조합차이니스햄스터오바리세포로부터발현된수두바이러스의지피i당단백질의정제방법
US6313127B1 (en) 1996-02-02 2001-11-06 Zeneca Limited Heterocyclic compounds useful as pharmaceutical agents
TR199801531T2 (xx) * 1996-02-09 1998-10-21 Smithkline Beecham Biologicals S.A. Zoster vir�s geni ve �r�n�ne kar�� a��lar.
US7112331B2 (en) 1996-02-09 2006-09-26 Smithkline Beecham Biologicals, S.A. Vaccines against varicella zoster virus gene 63 product
US5710248A (en) * 1996-07-29 1998-01-20 University Of Iowa Research Foundation Peptide tag for immunodetection and immunopurification
US6210683B1 (en) 1997-09-05 2001-04-03 Merck & Co., Inc. Stabilizers containing recombinant human serum albumin for live virus vaccines
JP6099573B2 (ja) * 2011-01-31 2017-03-22 ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア 新規なヘルペス抗原をコードする核酸分子、それを含むワクチン及びその使用方法
CN115210249A (zh) * 2020-02-28 2022-10-18 赛特瑞恩股份有限公司 水痘带状疱疹病毒融合蛋白以及包含该融合蛋白的免疫原性组合物
CN114081943B (zh) * 2021-11-08 2024-04-02 中国医学科学院医学生物学研究所 一种水痘-带状疱疹mRNA疫苗组合物及其制备方法和应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0211756A1 (de) * 1985-08-01 1987-02-25 Merck & Co. Inc. Assay für Varicella-Zoster-Virus (VZV)-Antikörper
US4686101A (en) * 1985-08-02 1987-08-11 Merck & Co., Inc. Vaccine against varicella-zoster virus
US4665159A (en) * 1985-11-07 1987-05-12 Miles Laboratories, Inc. High titer varicella-zoster immune globulin for intravenous administration

Also Published As

Publication number Publication date
EP0244155B1 (de) 1992-03-11
IE871169L (en) 1987-11-02
DK222587A (da) 1987-11-03
US4952674A (en) 1990-08-28
EP0244155A1 (de) 1987-11-04
ES2039239T3 (es) 1995-04-01
JP2530847B2 (ja) 1996-09-04
DK222587D0 (da) 1987-05-01
DE3777233D1 (de) 1992-04-16
JPS62285792A (ja) 1987-12-11
IE59791B1 (en) 1994-04-06
US5306635A (en) 1994-04-26

Similar Documents

Publication Publication Date Title
DE3777233D1 (de) Impfstoff gegen varicella-zoster-virus.
Keller et al. Identification and structure of the gene encoding gpII, a major glycoprotein of varicella-zoster virus
EP0405867B1 (de) Verbindungen
DE3588022T3 (de) Pre-S genkodierte Hepatitis B Peptide und diese enthaltende Immunogene und Vakzine
NO874750D0 (no) Bestemte dna-sekvenser avledet fra en papillomavirusgenom, deres bruk i in vitro diagnostikk og produksjon av antigene preparater.
FI863041A0 (fi) Fusionsprotein, foerfarande foer deras framstaellning och deras anvaendning.
NO167359C (no) Fremgangsmaate for fremstilling av en vaksine mot infeksjon av hepatitis b virus.
DE69131513D1 (de) Für abgeänderte retrovirale GAG-Polypeptide kodierende DNA-Sequenzen und diese enthaltende Impfstoffe oder Aggregate davon
HUT41845A (en) Process for preparing peptides
BR9303226A (pt) Processo e vacina para produzir anticorpos ou imundade mediada por celulas e adenovirus recombinante
AU605155B2 (en) A structural phosphoprotein (PP 15) of human cytomegalovirus, and the preparation and use thereof
ES8505253A1 (es) Un procedimiento para preparar un organismo unicelular que tiene una secuencia de adn que codifica un plipeptid0 que tiene un determinante inmunorreactivo u antigeno de una glicoproteina de virus de herpes simplex.
SE9903031D0 (sv) Peptide mixture and vaccine against a chronic viral infection
DE69231705D1 (de) Gag-Env Fusion-Antigen aus HIV
Petrovskis et al. A small open reading frame in pseudorabies virus and implications for evolutionary relationships between herpesviruses
BG105065A (en) A vaccine-induced hepatitis b viral strain and uses thereof
Sauer et al. Amino acid sequence of p15 from avian myeloblastosis virus complex
SE8601940D0 (sv) Preparation of fused proteins, antibodies and processes therefor
ATE93543T1 (de) Varicella-zoster-virus als lebende rekombinante vakzine.
HUT62330A (en) Process for producing recombinant vaccines against marek disease
Varsanyi et al. F1 polypeptides of two canine distemper virus strains: variation in the conserved N-terminal hydrophobic region
DE59814427D1 (de) Immunreaktive Bereiche des Glycoproteins gpII des Varicella Zoster-Virus (VZV)
TH6687A (th) ชิ้นส่วนของจีนที่มีรหัสสำหรับกลิโคโปรตีนของไวรัสโรคกลัวน้ำและกรรมวิธีสำหรับเตรียมกลีโคโปรตีนของไวรัสโรคกลัวน้ำที่ใช้จีนนั้น
TH6687EX (th) ชิ้นส่วนของจีนที่มีรหัสสำหรับกลิโคโปรตีนของไวรัสโรคกลัวน้ำและกรรมวิธีสำหรับเตรียมกลีโคโปรตีนของไวรัสโรคกลัวน้ำที่ใช้จีนนั้น
TH46562A3 (th) สายพันธุ์ไวรัสมิวแทนท์ฃเฮพาไททิส บี ของคนและการใช้งานของมัน