CO5300406A1 - Vacuna - Google Patents
VacunaInfo
- Publication number
- CO5300406A1 CO5300406A1 CO00028931A CO00028931A CO5300406A1 CO 5300406 A1 CO5300406 A1 CO 5300406A1 CO 00028931 A CO00028931 A CO 00028931A CO 00028931 A CO00028931 A CO 00028931A CO 5300406 A1 CO5300406 A1 CO 5300406A1
- Authority
- CO
- Colombia
- Prior art keywords
- vaccine
- derivative
- antigen
- immunogenic
- rsv
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/155—Paramyxoviridae, e.g. parainfluenza virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
- A61K39/092—Streptococcus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55561—CpG containing adjuvants; Oligonucleotide containing adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6068—Other bacterial proteins, e.g. OMP
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/70—Multivalent vaccine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18511—Pneumovirus, e.g. human respiratory syncytial virus
- C12N2760/18534—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Virology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Mycology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pulmonology (AREA)
- Molecular Biology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
Una formulación de vacuna que comprende un antígeno RSV y un oligonucleótido CpG inmuonestimulante.Una formulación de vacuna como la reivindicada en la reivindicación 1 en la que los antígenos RSV se seleccionan entre el grupo: proteína F o derivado inmunogénico de ésta, proteína G o derivado inmunogénico de ésta o proteína de fusión FG o derivado inmunogénico de ésta, y RSV inactivado.Una vacuna como la reivindicada en las reivindicaciones 1 o 2, en la que el derivado es un antígeno esencialmente desprovisto de un dominio transmembrana.Una vacuna como la reivindicada en las reivindicaciones 1 a 3, en la que el derivado es un antígeno en el que al menos un codón no preferido o menos preferido se ha reemplazado por un codón preferido que codifica el mismo aminoácido.Una formulación de vacuna como la reivindicada en cualquiera de las reivindicaciones 1 a 4, que comprende además una sal de aluminio o un coadyuvante de saponina.Una vacuna como la reivindicada en cualquiera de las reivindicaciones 1 a 5 en la que el oligonucleótido comprende dos dinucleótidos CpG. Una vacuna como la reivindicada en cualquiera de las reivindicaciones 1 a 6 en la que el oligonucleótido CpG tiene una longitud de 15 a 45 nucleótidos.Una vacuna como la reivindicada en cualquiera de las reivindicaciones 1 a 7 en la que el oligonucleótido CpG comprende al menos un enlace internucleotídico fosforotioato.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9909077.1A GB9909077D0 (en) | 1999-04-20 | 1999-04-20 | Novel compositions |
| GBGB9915106.0A GB9915106D0 (en) | 1999-06-28 | 1999-06-28 | Vaccine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CO5300406A1 true CO5300406A1 (es) | 2003-07-31 |
Family
ID=26315443
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CO00028931A CO5300406A1 (es) | 1999-04-20 | 2000-04-19 | Vacuna |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP1171158A2 (es) |
| AR (1) | AR023534A1 (es) |
| AU (1) | AU762857B2 (es) |
| CA (1) | CA2370708A1 (es) |
| CO (1) | CO5300406A1 (es) |
| HK (1) | HK1045099A1 (es) |
| WO (1) | WO2000062802A2 (es) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20010046967A1 (en) | 2000-03-10 | 2001-11-29 | Gary Van Nest | Methods of preventing and treating respiratory viral infection using immunomodulatory polynucleotide |
| US20020098199A1 (en) | 2000-03-10 | 2002-07-25 | Gary Van Nest | Methods of suppressing hepatitis virus infection using immunomodulatory polynucleotide sequences |
| US7157437B2 (en) | 2000-03-10 | 2007-01-02 | Dynavax Technologies Corporation | Methods of ameliorating symptoms of herpes infection using immunomodulatory polynucleotide sequences |
| AU2001285421A1 (en) * | 2000-08-10 | 2002-02-18 | Henry M. Jackson Foundation For The Advancement Of Military Medicine | Vaccine against rsv |
| CA2388049A1 (en) | 2002-05-30 | 2003-11-30 | Immunotech S.A. | Immunostimulatory oligonucleotides and uses thereof |
| US9815886B2 (en) | 2014-10-28 | 2017-11-14 | Adma Biologics, Inc. | Compositions and methods for the treatment of immunodeficiency |
| US10259865B2 (en) | 2017-03-15 | 2019-04-16 | Adma Biologics, Inc. | Anti-pneumococcal hyperimmune globulin for the treatment and prevention of pneumococcal infection |
| CN110052237A (zh) * | 2019-04-19 | 2019-07-26 | 贺州学院 | 一种多孔重质碳酸钙吸附材料的制备方法 |
| AU2021229710A1 (en) | 2020-03-01 | 2022-10-06 | Dynavax Technologies Corporation | CPG-adjuvanted SARS-CoV-2 virus vaccine |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL7015493A (es) * | 1969-11-14 | 1971-05-18 | ||
| US6764682B1 (en) * | 1994-06-16 | 2004-07-20 | Aventis Pasteur Limited | Adjuvant compositions containing more than one adjuvant |
| US6207646B1 (en) * | 1994-07-15 | 2001-03-27 | University Of Iowa Research Foundation | Immunostimulatory nucleic acid molecules |
| AU6908598A (en) * | 1996-10-29 | 1998-05-22 | Smithkline Beecham Biologicals (Sa) | Purification of respiratory syncytial virus antigens |
| EP0855184A1 (en) * | 1997-01-23 | 1998-07-29 | Grayson B. Dr. Lipford | Pharmaceutical composition comprising a polynucleotide and an antigen especially for vaccination |
| GB9727262D0 (en) * | 1997-12-24 | 1998-02-25 | Smithkline Beecham Biolog | Vaccine |
| SI1077722T1 (sl) * | 1998-05-22 | 2007-02-28 | Ottawa Health Research Inst | Metode in produkti za induciranje sluznicne imunosti |
-
2000
- 2000-04-17 AU AU45525/00A patent/AU762857B2/en not_active Ceased
- 2000-04-17 WO PCT/EP2000/003516 patent/WO2000062802A2/en not_active Application Discontinuation
- 2000-04-17 CA CA002370708A patent/CA2370708A1/en not_active Abandoned
- 2000-04-17 EP EP00926986A patent/EP1171158A2/en not_active Withdrawn
- 2000-04-18 AR ARP000101807A patent/AR023534A1/es unknown
- 2000-04-19 CO CO00028931A patent/CO5300406A1/es not_active Application Discontinuation
-
2002
- 2002-06-27 HK HK02104795.7A patent/HK1045099A1/zh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2000062802A2 (en) | 2000-10-26 |
| AR023534A1 (es) | 2002-09-04 |
| EP1171158A2 (en) | 2002-01-16 |
| AU762857B2 (en) | 2003-07-10 |
| CA2370708A1 (en) | 2000-10-26 |
| AU4552500A (en) | 2000-11-02 |
| WO2000062802A3 (en) | 2001-01-11 |
| HK1045099A1 (zh) | 2002-11-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES2572563T3 (es) | Oligonucleótidos inmunoestimulantes | |
| IL150602A (en) | Proteosome influenza vaccine, method for preparing such and use thereof | |
| AR014181A1 (es) | Formulaciones de vacuna capaces de incrementar las inmunorespuestas a los antigenos t-independientes y secuencias de deoxiribo o ribonucleoticosincluidos en dichas formulaciones; metodo para inducir inmunorespuestas a dichos t antigenos o antigenos de polisacaridos conjugados | |
| EA200100425A1 (ru) | Новые способы терапевтической вакцинации | |
| ATE549032T1 (de) | Adjuvanzverbindungen zur verbesserung von immunreaktionen auf polynukleotid-basierten impfstoffen | |
| NZ733383A (en) | Oil-based adjuvants | |
| US10987420B2 (en) | Synthetic conjugate of CpG DNA and T-help/CTL peptide | |
| OA13278A (en) | C-Class oligonucleotide analogs with enhanced immunostimulatory potency. | |
| Lingnau et al. | Poly-L-arginine synergizes with oligodeoxynucleotides containing CpG-motifs (CpG-ODN) for enhanced and prolonged immune responses and prevents the CpG-ODN-induced systemic release of pro-inflammatory cytokines | |
| CA2536139A1 (en) | Nucleic acid-lipophilic conjugates | |
| BRPI0414381A (pt) | composição de adjuvante, composição ou composições imunogênica(s), composição de vacina, processo para a fabricação de uma composição imunogênica, composição ou composições farmacêutica(s), kit, métodos para tratar um paciente que sofre de, ou que é suscetìvel a, um tumor, para incrementar uma resposta imune de um mamìfero a um antìgeno e para suscitar uma resposta imune em m mamìfero contra um estado de doença, usos de uma imidazoquinolina ou derivado da mesma e gm-csf e dos componentes | |
| CY1113553T1 (el) | Μεθυλιωση πλασμιδιακων κομιστων | |
| ATE315405T1 (de) | Cpg-zusammensetzungen, saponin-adjuvantien und verfahren zu deren verwendung | |
| MX9306841A (es) | Vacuna a base de ureasa contra la infeccion por helicobacter en mamiferos. | |
| PE20011217A1 (es) | Composicion farmaceutica para modulacion inmunologica y preparacion de vacunas | |
| NO20015073L (no) | Vaksiner | |
| BR9712970A (pt) | Método para produção de vacina para proteção contra virus sincitial respiratório, mistura de proteìna de fusão purificada, composição imunogênica | |
| CO5300406A1 (es) | Vacuna | |
| ES2158034T3 (es) | Derivado de benzotiepina opticamente activo, su preparacion y uso. | |
| ES2137310T3 (es) | Vacuna contra una infeccion por streptococcus suis. | |
| ES2039239T3 (es) | Vacuna contra el virus varicela-zoster. | |
| AR009365A1 (es) | Vacunas del virus de la fiebre aftosa (fmdv), peptidos, secuencias de adn y el uso de los peptidos en sistemas de deteccion y el uso de la vacuna fmdc para la preparacion de una composicion para inmunizar cerdos y ganado vacuno | |
| SE9903534D0 (sv) | Vaccin | |
| DK0762895T3 (da) | Syntetisk vaccine til beskyttelse mod infektion med human immundefektvirus | |
| AR022662A1 (es) | Acidos nucleicos y proteinas del gen mhp3 de mycoplasma hyopneumoniae y sus usos |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Application withdrawn |