ES2037599A1 - Metodo de cultivo para la preparacion de una vacuna tifoidea oral de tipo vivo - Google Patents

Metodo de cultivo para la preparacion de una vacuna tifoidea oral de tipo vivo

Info

Publication number
ES2037599A1
ES2037599A1 ES919101949A ES9101949A ES2037599A1 ES 2037599 A1 ES2037599 A1 ES 2037599A1 ES 919101949 A ES919101949 A ES 919101949A ES 9101949 A ES9101949 A ES 9101949A ES 2037599 A1 ES2037599 A1 ES 2037599A1
Authority
ES
Spain
Prior art keywords
bacteria
medium
hours
cultivating
cultivation method
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES919101949A
Other languages
English (en)
Other versions
ES2037599B1 (es
Inventor
Bong Wha Park
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BORYUNG BIOPHARMA CO Ltd
Original Assignee
BORYUNG BIOPHARMA CO Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BORYUNG BIOPHARMA CO Ltd filed Critical BORYUNG BIOPHARMA CO Ltd
Publication of ES2037599A1 publication Critical patent/ES2037599A1/es
Application granted granted Critical
Publication of ES2037599B1 publication Critical patent/ES2037599B1/es
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/04Preserving or maintaining viable microorganisms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/025Enterobacteriales, e.g. Enterobacter
    • A61K39/0275Salmonella
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/522Bacterial cells; Fungal cells; Protozoal cells avirulent or attenuated
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541Mucosal route
    • A61K2039/542Mucosal route oral/gastrointestinal
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Public Health (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

METODO DE CULTIVO PARA LA PREPARACION DE UNA VACUNA TIFOIDEA ORAL DE TIPO VIVO. METODO DE CULTIVO PARA OBTENER VACUNA TIFOIDEA ORAL VIVA, QUE COMPRENDE LAS FASES DE CULTIVO DE LAS BACTERIAS SIMIENTE OBTENIDAS A PARTIR DE CEPA TIFOIDEA TY21A EN MEDIO BHI, SUSPENDIENDO LAS BACTERIAS CULTIVADAS EN UN MEDIO DE PROTECCION Y LIOFILIZANDO LAS BACTERIAS SUSPENDIDAS EN AMPOLLA, HACIENDO REVIVIR LAS BACTERIAS LIOFILIZADAS E INOCULANDO LAS BACTERIAS QUE SE HAN HECHO REVIVIR EN MEDIO DE PRODUCCION, CULTIVANDO LAS BACTERIAS EN UN FERMENTADOR, Y LIOFILIZANDO LAS BACTERIAS Y FORMULANDO LAS MISMAS PARA UTILIZACION ORAL.
ES9101949A 1990-09-05 1991-08-28 Metodo de cultivo para la preparacion de una vacuna tifoidea oral de tipo vivo Expired - Fee Related ES2037599B1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1019900014019A KR930001382B1 (ko) 1990-09-05 1990-09-05 경구용 장티프스 생균백신 및 그의 제조방법

Publications (2)

Publication Number Publication Date
ES2037599A1 true ES2037599A1 (es) 1993-06-16
ES2037599B1 ES2037599B1 (es) 1994-02-01

Family

ID=19303271

Family Applications (1)

Application Number Title Priority Date Filing Date
ES9101949A Expired - Fee Related ES2037599B1 (es) 1990-09-05 1991-08-28 Metodo de cultivo para la preparacion de una vacuna tifoidea oral de tipo vivo

Country Status (8)

Country Link
JP (1) JPH0771471B2 (es)
KR (1) KR930001382B1 (es)
CN (1) CN1056876C (es)
CH (1) CH683187A5 (es)
ES (1) ES2037599B1 (es)
GB (1) GB2248241B (es)
IL (1) IL99138A (es)
TW (1) TW209244B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2727128B1 (fr) * 1994-11-17 1997-01-17 Fdm Pharma Moyens pour le traitement de prelevements susceptibles de renfermer des microorganismes pathogenes
GB0900350D0 (en) * 2009-01-09 2009-02-11 Cambridge Entpr Ltd Formulations of viable bacteria for oral delivery
LT2794849T (lt) 2011-12-22 2017-12-11 Vaximm Ag Didelio produktyvumo susilpnintų salmonella padermių gamybos būdas
CN104519908B (zh) 2012-07-05 2020-10-30 万科斯蒙股份有限公司 用于胰腺癌患者的dna疫苗
GB2564481B (en) * 2017-07-14 2019-10-23 4D Pharma Leon S L U Process

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3856935A (en) * 1971-04-29 1974-12-24 Schweiz Serum & Impfinst Oral typhoid vaccine and method of preparing the same

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5522448A (en) * 1978-08-03 1980-02-18 Shin Meiwa Ind Co Ltd Rotary working table
US4632830A (en) * 1981-07-31 1986-12-30 The United States Of America As Represented By The Secretary Of The Army Oral vaccine for immunization against enteric disease
US4879239A (en) * 1983-11-03 1989-11-07 American Type Culture Collection Method of culturing freeze-dried microorganisms and resultant preparation

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3856935A (en) * 1971-04-29 1974-12-24 Schweiz Serum & Impfinst Oral typhoid vaccine and method of preparing the same

Also Published As

Publication number Publication date
CH683187A5 (fr) 1994-01-31
GB2248241B (en) 1995-01-04
IL99138A (en) 1995-10-31
CN1060110A (zh) 1992-04-08
KR930001382B1 (ko) 1993-02-27
TW209244B (es) 1993-07-11
KR920006496A (ko) 1992-04-27
GB9117918D0 (en) 1991-10-09
GB2248241A (en) 1992-04-01
JPH0771471B2 (ja) 1995-08-02
ES2037599B1 (es) 1994-02-01
IL99138A0 (en) 1992-07-15
CN1056876C (zh) 2000-09-27
JPH05336950A (ja) 1993-12-21

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Effective date: 20111025