ES2018909A6 - Un metodo para producir un polipeptido util en un metodo y sistema de diagnostico para el ensayo de la presencia de anticuerpos anti-ebna enuna muestra corporal. - Google Patents

Un metodo para producir un polipeptido util en un metodo y sistema de diagnostico para el ensayo de la presencia de anticuerpos anti-ebna enuna muestra corporal.

Info

Publication number
ES2018909A6
ES2018909A6 ES8902818A ES8902818A ES2018909A6 ES 2018909 A6 ES2018909 A6 ES 2018909A6 ES 8902818 A ES8902818 A ES 8902818A ES 8902818 A ES8902818 A ES 8902818A ES 2018909 A6 ES2018909 A6 ES 2018909A6
Authority
ES
Spain
Prior art keywords
epstein
nuclear antigen
systems
barr virus
synthetic polypeptides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
ES8902818A
Other languages
English (en)
Inventor
Gary Rhodes
Richard S Smith
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Scripps Research Institute
Original Assignee
Scripps Clinic and Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scripps Clinic and Research Foundation filed Critical Scripps Clinic and Research Foundation
Publication of ES2018909A6 publication Critical patent/ES2018909A6/es
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/245—Herpetoviridae, e.g. herpes simplex virus
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983—Viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/6081—Albumin; Keyhole limpet haemocyanin [KLH]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16111—Cytomegalovirus, e.g. human herpesvirus 5
    • C12N2710/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16211—Lymphocryptovirus, e.g. human herpesvirus 4, Epstein-Barr Virus
    • C12N2710/16222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16211—Lymphocryptovirus, e.g. human herpesvirus 4, Epstein-Barr Virus
    • C12N2710/16234—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Food Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

METODO PARA PRODUCIR UN POLIPEPTIDO UTIL EN UN METODO Y SISTEMA DE DIAGNOSTICO PARA EL ENSAYO DE LA PRESENCIA DE ANTICUERPOS ANTI-BBNA EN UNA MUESTRA CORPORAL. SE DESCRIBEN ANTIGENOS, INMUNOGENOS, INOCULOS Y PARTICULARMENTE METODOS Y SISTEMAS DE DIAGNOSTICO RELACIONADOS CON EL ANTIGENO NUCLEAR DEL VIRUS EPSTEIN-BARR, ASI COMO EL METODO PARA PRODUCIR EL POLIPEPTIDO QUE SE UTILIZA EN DICHOS SISTEMAS Y QUE CONSISTE EN UN COPOLIMERO AL AZAR, SINTETICO, CONTENIENDO DE 6 A 40 RESIDUOS DE AMINOACIDOS, APROXIMADAMENTE, CON UNA SECUENCIA CORRESPONDIENTE A LA SECUENCIA DE UN ANTIGENO POLIPEPTIDO CODIFICADO POR CMV. LOS METODOS Y SISTEMAS DE DIAGNOSTICO SON PARTICULARMENTE UTILES EN LA IDENTIFICACION DE INFECCION POR MUNONUCLEOSIS DURANTE SU FASE AGUDA.
ES8902818A 1988-08-09 1989-08-08 Un metodo para producir un polipeptido util en un metodo y sistema de diagnostico para el ensayo de la presencia de anticuerpos anti-ebna enuna muestra corporal. Expired - Fee Related ES2018909A6 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/230,250 US5717065A (en) 1984-08-08 1988-08-09 Synthetic polypeptides and antibodies related to epstein-barr virus nuclear antigen

Publications (1)

Publication Number Publication Date
ES2018909A6 true ES2018909A6 (es) 1991-05-16

Family

ID=22864499

Family Applications (1)

Application Number Title Priority Date Filing Date
ES8902818A Expired - Fee Related ES2018909A6 (es) 1988-08-09 1989-08-08 Un metodo para producir un polipeptido util en un metodo y sistema de diagnostico para el ensayo de la presencia de anticuerpos anti-ebna enuna muestra corporal.

Country Status (13)

Country Link
US (1) US5717065A (es)
EP (1) EP0428629B1 (es)
AT (1) ATE134648T1 (es)
AU (1) AU643188B2 (es)
CA (1) CA1340446C (es)
DE (1) DE68925819T2 (es)
DK (1) DK175828B1 (es)
ES (1) ES2018909A6 (es)
FI (1) FI102381B1 (es)
GR (1) GR890100501A (es)
NO (1) NO309720B1 (es)
PT (1) PT91397B (es)
WO (1) WO1990001495A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5374517A (en) * 1989-11-24 1994-12-20 Council Of The Queensland Institute Of Medical Research IM peptides
JPH04310861A (ja) * 1991-04-09 1992-11-02 Kazuo Yanagi 抗ｅｂｎａ抗体の測定方法および抗ｅｂｎａ抗体測定キット
ES2221922T3 (es) * 1992-09-14 2005-01-16 Biomerieux B.V. Peptidos del virus de epstein-barr y anticuerpos contra estos peptidos.
US5833991A (en) * 1995-04-10 1998-11-10 Cobra Therapeutics, Ltd. Glycine-containing sequences conferring invisibility to the immune system

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4686282A (en) * 1983-08-12 1987-08-11 Immunetech, Inc. Immunotherapeutic polypeptide agents which block immune complex binding to immunoglobulin Fc receptors
US5116725A (en) * 1984-08-08 1992-05-26 Scripps Clinic And Research Foundation Assay for Epstein-Barr virus infection with solid phase bound synthetic polypeptides
US4654419A (en) * 1984-08-08 1987-03-31 Scripps Clinic And Research Foundation Synthetic polypeptides and antibodies related to epstein-barr virus nuclear antigen
ZA846192B (en) * 1984-08-09 1986-03-26 Merck Patent Gmbh Immunotherapeutic polypeptide agents

Also Published As

Publication number Publication date
DE68925819T2 (de) 1996-10-02
PT91397B (pt) 1995-05-04
ATE134648T1 (de) 1996-03-15
DK175828B1 (da) 2005-03-14
DE68925819D1 (de) 1996-04-04
WO1990001495A1 (en) 1990-02-22
EP0428629B1 (en) 1996-02-28
EP0428629A4 (en) 1991-12-27
US5717065A (en) 1998-02-10
FI102381B (fi) 1998-11-30
DK21191A (da) 1991-04-04
FI910587A0 (fi) 1991-02-07
EP0428629A1 (en) 1991-05-29
CA1340446C (en) 1999-03-16
GR890100501A (el) 1991-12-30
AU643188B2 (en) 1993-11-11
NO910479L (no) 1991-04-05
NO910479D0 (no) 1991-02-07
DK21191D0 (da) 1991-02-07
FI102381B1 (fi) 1998-11-30
NO309720B1 (no) 2001-03-19
AU4400089A (en) 1990-03-05
PT91397A (pt) 1990-03-08

Similar Documents

Publication Publication Date Title
DK532284A (da) Fremgangsmaade til bestemmelse af antigenaktive aminosyresekvenser
DE3750339D1 (de) HTLV-III umhüllende Peptiden.
SG47062A1 (en) Synthetic antigens for the detection of antibodies to hepatitis virus
EP0280813A3 (en) Synthetic polypeptides and antibodies related to epstein-barr virus early diffuse antigen
GB2102810B (en) Human interferon-related peptides antigens antibodies and process for preparing the same
GR3018773T3 (en) Antibodies to human papillomavirus latent proteins, diagnostic systems and methods.
EP0284587A3 (en) Synthetic peptide antigens for the detection of hiv-1 infection
HUT44619A (en) Process for preparing monoclonal antibodies and peptides suitable for the treatment and detection of hiv infections
ATE123072T1 (de) Testsystem zum nachweis von antikörpern und methode zur herstellung nichtmenschlicher immunantikörper.
CA2111325A1 (en) Detection of mammalian immunodeficiency viruses
GR3018371T3 (en) Method for identifying or determining proteins and applications therefor.
IL132414A0 (en) Type alpha platelet derived growth factor receptor gene
ES2018909A6 (es) Un metodo para producir un polipeptido util en un metodo y sistema de diagnostico para el ensayo de la presencia de anticuerpos anti-ebna enuna muestra corporal.
AU608413B2 (en) Mouse monoclonal antibody (5-21-3) to human immunodeficiency virus gp41 protein
EP0582243A3 (de) HCV Peptidantigene und Verfahren zur Bestimmung von HCV.
JPS55141452A (en) Synthetic polypeptide
CA2120342A1 (en) Epstein-barr virus peptides and antibodies against these peptides
Poulsen The nature of an iso-antigen of the human sperm membrane
ATE122150T1 (de) Einschritt-immuntest zur bestimmung von antigen- spezifischen antikörpern aller immunglobulin- klassen und dazu geeignetes mittel.
SG145521A1 (en) Synthetic antigens for the detection of antibodies to hepatitis c virus

Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20100412