ES2006484A6 - Dispositivo y metodo para determinar la presencia de antigenos en una muestra - Google Patents

Dispositivo y metodo para determinar la presencia de antigenos en una muestra

Info

Publication number
ES2006484A6
ES2006484A6 ES8701677A ES8701677A ES2006484A6 ES 2006484 A6 ES2006484 A6 ES 2006484A6 ES 8701677 A ES8701677 A ES 8701677A ES 8701677 A ES8701677 A ES 8701677A ES 2006484 A6 ES2006484 A6 ES 2006484A6
Authority
ES
Spain
Prior art keywords
antigen
antibodies
zone
bound
trapping zone
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES8701677A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of ES2006484A6 publication Critical patent/ES2006484A6/es
Expired legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/537—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54386—Analytical elements
    • G01N33/54387—Immunochromatographic test strips
    • G01N33/54391—Immunochromatographic test strips based on vertical flow
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/558—Immunoassay; Biospecific binding assay; Materials therefor using diffusion or migration of antigen or antibody
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/807—Apparatus included in process claim, e.g. physical support structures
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/819—Multifunctional antigen or antibody
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/824—Immunological separation techniques
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/828—Protein A

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

DISPOSITIVO Y METODO PARA DETERMINAR LA PRESENCIA DE ANTIGENOS EN UNA MUESTRA, COMPRENDIENDO EL DISPOSITIVO UNA ZONA DE ATRAPAMIENTO QUE CAPTURA ANTICUERPOS UNIDOS A ENZIMAS, PERO NO ANTICUERPOS ENLAZADOS CON PARTICULAS DE TRANSPORTE, Y UNA ZONA DE SUSTRATO QUE REACCIONA CON ANTICUERPOS UNIDOS A ENZIMAS PARA PRODUCIR UNA REACCION INDICATIVA DE ANTICUERPOS. EL METODO COMPRENDE MEZCLAR UNA MUESTRA CON DOS CLASES DE ANTICUERPOS ESPECIFICOS PARA EL ANTIGENO ENSAYADO, PERO REACCIONANTES CON DIFERENTES DOMINIOS DEL ANTIGENO, ESTANDO LOS ANTIGENOS DE LA PRIMERA CLASE ENLAZADOS CON DICHAS PARTICULAS DE TRANSPORTE Y ESTANDO LOS ANTIGENOS DE LA SEGUNDA CLASE UNIDOS A ENZIMAS, ENLAZANDOSE AMBAS CLASES DE ANTICUERPOS CON EL ANTIGENO Y PASANDO A LA ZONA DE SUSTRATO EN QUE SE PRODUCE LA REACCION INDICATIVA DE LA PRESENCIA DE DICHO ANTIGENO. EL INVENTO ES APLICABLE A LA DETECCION DEL EMBARAZO.
ES8701677A 1986-06-09 1987-06-08 Dispositivo y metodo para determinar la presencia de antigenos en una muestra Expired ES2006484A6 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/871,857 US4837145A (en) 1986-06-09 1986-06-09 Layered immunoassay using antibodies bound to transport particles to determine the presence of an antigen

Publications (1)

Publication Number Publication Date
ES2006484A6 true ES2006484A6 (es) 1989-05-01

Family

ID=25358311

Family Applications (1)

Application Number Title Priority Date Filing Date
ES8701677A Expired ES2006484A6 (es) 1986-06-09 1987-06-08 Dispositivo y metodo para determinar la presencia de antigenos en una muestra

Country Status (17)

Country Link
US (1) US4837145A (es)
JP (1) JPS6340859A (es)
AU (1) AU604020B2 (es)
BE (1) BE1001736A4 (es)
CA (1) CA1293442C (es)
DE (1) DE3718621A1 (es)
DK (1) DK282987A (es)
ES (1) ES2006484A6 (es)
FR (1) FR2599845B1 (es)
GB (1) GB2191577B (es)
GR (1) GR870872B (es)
IT (1) IT1205137B (es)
LU (1) LU86909A1 (es)
NL (1) NL8701324A (es)
NZ (1) NZ220560A (es)
SE (1) SE463894B (es)
ZA (1) ZA873748B (es)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5622871A (en) 1987-04-27 1997-04-22 Unilever Patent Holdings B.V. Capillary immunoassay and device therefor comprising mobilizable particulate labelled reagents
ATE225509T1 (de) * 1987-04-27 2002-10-15 Inverness Medical Switzerland Testgerät zur durchführung von spezifischen bindungsprüfungen
US5073344A (en) * 1987-07-17 1991-12-17 Porex Technologies Corp. Diagnostic system employing a unitary substrate to immobilize microspheres
US5024238A (en) * 1989-01-10 1991-06-18 Cancer Diagnostics, Inc. Blood withdrawing apparatus and antigen testing method
US6352862B1 (en) * 1989-02-17 2002-03-05 Unilever Patent Holdings B.V. Analytical test device for imuno assays and methods of using same
US6168956B1 (en) 1991-05-29 2001-01-02 Beckman Coulter, Inc. Multiple component chromatographic assay device
US5877028A (en) 1991-05-29 1999-03-02 Smithkline Diagnostics, Inc. Immunochromatographic assay device
US5998220A (en) 1991-05-29 1999-12-07 Beckman Coulter, Inc. Opposable-element assay devices, kits, and methods employing them
IL102486A (en) * 1991-10-04 1997-11-20 Orgenics Ltd Method and apparatus for detection of nucleic acid sequences with a nucleic acid probe
US5324634A (en) * 1992-03-31 1994-06-28 The Research Foundation Of State University Of New York Diagnostic tests measuring gelatinase/inhibitor complexes for detection of aggressive and metastatic cancer
US5597532A (en) * 1994-10-20 1997-01-28 Connolly; James Apparatus for determining substances contained in a body fluid
US5874216A (en) 1996-02-23 1999-02-23 Ensys Environmental Products, Inc. Indirect label assay device for detecting small molecules and method of use thereof
EP0888552A1 (en) * 1996-03-20 1999-01-07 Serex, Inc. Chromatographic immunoassay device and method utilizing particle valency for quantitation
US5942407A (en) * 1996-06-25 1999-08-24 Immunomatrix, Inc. Light-emitting immunoassay
US5879951A (en) 1997-01-29 1999-03-09 Smithkline Diagnostics, Inc. Opposable-element assay device employing unidirectional flow
US5939252A (en) 1997-05-09 1999-08-17 Lennon; Donald J. Detachable-element assay device
US5970782A (en) * 1997-05-16 1999-10-26 Life Technologies, Inc. Gradient filtration apparatus
US20050266499A1 (en) * 2001-04-25 2005-12-01 Rockeby Biomed Corporation, Ltd. Method and apparatus for testing for presence or absence of select biological substances
US8956859B1 (en) 2010-08-13 2015-02-17 Aviex Technologies Llc Compositions and methods for determining successful immunization by one or more vaccines

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0073593A1 (en) * 1981-09-01 1983-03-09 E.I. Du Pont De Nemours And Company Size-exclusion heterogeneous immunoassay
US4446232A (en) * 1981-10-13 1984-05-01 Liotta Lance A Enzyme immunoassay with two-zoned device having bound antigens
EP0092344A1 (en) * 1982-04-15 1983-10-26 AMERSHAM INTERNATIONAL plc Assay method
US4459361A (en) * 1982-06-04 1984-07-10 Angenics, Inc. Ligand assay with one or two particulate reagents and filter
EP0126772A1 (en) * 1982-12-03 1984-12-05 E.I. Du Pont De Nemours And Company Chromogenic support immunoassay
US4459358A (en) * 1982-12-29 1984-07-10 Polaroid Corporation Multilayer element for analysis
GB8305197D0 (en) * 1983-02-24 1983-03-30 Amersham Int Plc Assay methods
GB8331514D0 (en) * 1983-11-25 1984-01-04 Janssen Pharmaceutica Nv Visualization method
DE3342627A1 (de) * 1983-11-25 1985-06-05 Boehringer Mannheim Gmbh, 6800 Mannheim Immunchemischer schnelltest
US4703017C1 (en) * 1984-02-14 2001-12-04 Becton Dickinson Co Solid phase assay with visual readout
JPS6295463A (ja) * 1985-10-22 1987-05-01 Fuji Photo Film Co Ltd 生物学的反応生成物の分離方法
WO1987003690A1 (en) * 1985-12-10 1987-06-18 Murex Corporation Particle-bound binding component immunoassay

Also Published As

Publication number Publication date
GB2191577A (en) 1987-12-16
GB2191577B (en) 1990-08-01
CA1293442C (en) 1991-12-24
SE463894B (sv) 1991-02-04
DK282987D0 (da) 1987-06-03
LU86909A1 (fr) 1987-11-11
DE3718621C2 (es) 1990-06-21
ZA873748B (en) 1988-01-27
AU604020B2 (en) 1990-12-06
US4837145A (en) 1989-06-06
BE1001736A4 (nl) 1990-02-20
DK282987A (da) 1987-12-10
SE8702334D0 (sv) 1987-06-04
AU7345487A (en) 1987-12-10
GR870872B (en) 1987-10-06
IT1205137B (it) 1989-03-15
JPS6340859A (ja) 1988-02-22
GB8712777D0 (en) 1987-07-08
SE8702334L (sv) 1987-12-10
IT8720842A0 (it) 1987-06-09
FR2599845A1 (fr) 1987-12-11
DE3718621A1 (de) 1987-12-10
NZ220560A (en) 1989-01-06
NL8701324A (nl) 1988-01-04
FR2599845B1 (fr) 1990-08-24

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Legal Events

Date Code Title Description
SA6 Expiration date (snapshot 920101)

Free format text: 2007-06-08

FD1A Patent lapsed

Effective date: 20000201