ES2006438T3 - Aparato para analisis automatico. - Google Patents

Aparato para analisis automatico.

Info

Publication number
ES2006438T3
ES2006438T3 ES198888105418T ES88105418T ES2006438T3 ES 2006438 T3 ES2006438 T3 ES 2006438T3 ES 198888105418 T ES198888105418 T ES 198888105418T ES 88105418 T ES88105418 T ES 88105418T ES 2006438 T3 ES2006438 T3 ES 2006438T3
Authority
ES
Spain
Prior art keywords
reaction
reagent
reagents
sample
samples
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES198888105418T
Other languages
English (en)
Other versions
ES2006438A4 (es
Inventor
Takejirou Yokosuka
Kazutomi Yokota
Teruo Mochida
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Japan Tectron Instruments Corp
Original Assignee
Japan Tectron Instruments Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Japan Tectron Instruments Corp filed Critical Japan Tectron Instruments Corp
Publication of ES2006438A4 publication Critical patent/ES2006438A4/es
Application granted granted Critical
Publication of ES2006438T3 publication Critical patent/ES2006438T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584—Control arrangements for automatic analysers
    • G01N35/0092—Scheduling
    • G01N35/0095—Scheduling introducing urgent samples with priority, e.g. Short Turn Around Time Samples [STATS]
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/251—Colorimeters; Construction thereof
    • G01N21/253—Colorimeters; Construction thereof for batch operation, i.e. multisample apparatus
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/025—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations having a carousel or turntable for reaction cells or cuvettes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00346—Heating or cooling arrangements
    • G01N2035/00356—Holding samples at elevated temperature (incubation)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00346—Heating or cooling arrangements
    • G01N2035/00435—Refrigerated reagent storage
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00465—Separating and mixing arrangements
    • G01N2035/00534—Mixing by a special element, e.g. stirrer
    • G01N2035/00544—Mixing by a special element, e.g. stirrer using fluid flow
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584—Control arrangements for automatic analysers
    • G01N2035/0097—Control arrangements for automatic analysers monitoring reactions as a function of time
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04—Details of the conveyor system
    • G01N2035/0439—Rotary sample carriers, i.e. carousels
    • G01N2035/0446—Combinations of the above
    • G01N2035/0448—Combinations of the above composed of interchangeable ring elements
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N2035/1027—General features of the devices
    • G01N2035/1048—General features of the devices using the transfer device for another function
    • G01N2035/1058—General features of the devices using the transfer device for another function for mixing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/04—Batch operation; multisample devices
    • G01N2201/0415—Carrusel, sequential

Landscapes

  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Devices For Use In Laboratory Experiments (AREA)

Abstract

SE PRESENTA UN APARATO DE ANALISIS AUTOMATICO QUE SUMINISTRA PARA VARIAS OPERACIONES ANALITICAS EN DIAGNOSIS CLINICAS Y EXPERIMENTOS QUE INCLUYEN MEDIDAS DE LOS CAMBIOS EN LA ABSORVENCIA DE LUZ DE UN LARGO NUMERO DE MUESTRAS MEZCLADAS CON DIFERENTES REAGENTES DE UNA MANERA PROGRESIVA ANALISIS BIOQUIMICOS, ELECTROLITICOS, FLUORESCENTES, E INMUNOLOGICOS Y ANALISIS EIA DE MUESTRAS EN FASE SOLIDA. UNA PLURALIDAD DE MUESTRAS SE MANTIENEN, JUNTO CON DILUYENTES Y MUESTRAS DE EMERGENCIA, EN UNA SECUENCIA ORDENADA SOBRE UNA MESA DE MUESTRAS GIRATORIA QUE SE HACE GIRAR PASO A PASO PARA MOVER LAS MUESTRAS PROGRESIVAMENTE HASTA UNA POSICION DE SUCCION PREDETERMINADA EN LA CUAL UNA PIPETA DE MUESTRAS TOMA UNA CANTIDAD MEDIDA DE LA MUESTRA Y LA DISPENSA A UNO DE UNA PLURALIDAD DE ENVASES DE REACCION QUE ESTAN DISPUESTOS EN UNA SECUENCIA ORDENADA SOBRE UNA MESA DE REACCION CAPAZ DE GIRAR PREFERIBLEMENTE ALREDEDOR DE DICHA MESA DE MUESTRAS. AL MENOS UN PAR DE MESAS DE REAGENTES ESTAN DISPUESTAS, CADA UNALLEVANDO UNA PLURALIDAD DE REAGENTES DE DIFERENTES CLASES, SELECCIONADOS PARA VARIOS ANALISIS A REALIZARSE. SE SUMINISTRA UNA PRIMERA Y UNA SEGUNDA PIPETA DE REAGENTE QUE TOMAN UNA CANTIDAD MEDIDA DE UN REAGENTE PARTICULAR Y LO MEZCLAN CON CUALQUIER MUESTRA SELECCIONADA EN LOS ENVASES DE REACCION. CADA MEZCLA DE MUESTRA Y REAGENTE PUEDE SER EXPLORADA PARA MEDIR LA CANTIDAD DE ABSORVENCIA DE LUZ DURANTE UN PERIODO DE TIEMPO A MEDIDA QUE LOS ENVASES DE REACCION GIRAN SOBRE LA MESA DE REACCION MEDIANTE UN FOTOMETRO QUE INCLUYE UNA ARMADURA GIRATORIA QUE LLEVA SOBRE SI FILTROS PARA DIFERENTES LONGITUDES DE ONDA A TRAVES DE LAS CUALES EL HAZ OPTICO DE LA FUENTE DE LUZ SE HACE PASAR PARA ATRAVESAR EL ENVASE DE REACCION QUE VA A MEDIRSE MEDIANTE UN SENSOR OPTICO A MEDIDA QUE EL ENVASE DE REACCION GIRA. CADA TUBO DE REAGENTE ESTA PROVISTO DE UN AGITADOR QUE FUNCIONA, DESPUES DE CADA OPERACION DE DISPENSACION DEL TUBO DENTRO DEL ENVASE DE REACCION, PARA BATIR LA MEZCLA EN EL ENVASE DE REACCIONHASTA UN ESTADO HOMOGENEO PARA LA REACCION APROPIADA. AL MENOS UNA DE LAS MESAS DE REAGENTES ESTA DIVIDIDA EN UN COMPARTIMENTO DE TEMPERATURA AMBIENTE DONDE SE MANTIENEN LOS REAGENTES A TEMPERATURA AMBIENTE Y UN COMPARTIMENTO DE ENFRIADO CONECTADO A MEDIOS DE REFRIGERACION MEDIANTE TUBOS EN EL CUAL LOS REAGENTES SE MANTIENEN A UNA BAJA TEMPERATURA. EL COMPARTIMENTO DE TEMPERATURA AMBIENTE PUEDE COMPRENDE UN ELEMENTO CALENTADOR MONTADO EN EL FONDO DEL COMPARTIMENTO Y CONECTADO A UNA FUENTE DE POTENCIA A TRAVES DE UN CIRCUITO EXTENDIDO EN LA MESA DE REAGENTE. SE INCORPORA UN SISTEMA DE LIMPIEZA, QUE, MIENTRAS SE DETIENE EL FUNCIONAMIENTO DE DISPENSACION DEL REAGENTE DE LA PIPETA DURANTE EL CICLO DE FUNCIONAMIENTO ANALITICO EN UN INTERVALO PREDETERMINADO, PROVOCA QUE LA PIPETA DEL REAGENTE ABSORVA UNA CANTIDAD MEDIDA DE UNA SOLUCION DE UN DETERGENTE DESDE UNA PLURALIDAD DE ENVASES DE DETERGENTE DISPUESTOS EN ORDEN SOBRE LA MESA DE REAGENTES Y DESCARGUE EL FLUIDO ABSORVIDO DENTRO DE UN VASO DEREACCION MONTADO SOBRE LA MESA DE REACCION DE TAL FORMA QUE EL RESIDUO DE LOS REAGENTES QUE PUDIERA PERMANECER ADHERIDO A LOS TUBOS SEA ELIMINADO.
ES198888105418T 1987-04-06 1988-04-05 Aparato para analisis automatico. Expired - Lifetime ES2006438T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP8528587A JPH0634932B2 (ja) 1987-04-06 1987-04-06 試薬ボトルテ−ブルの温度調整構造

Publications (2)

Publication Number Publication Date
ES2006438A4 ES2006438A4 (es) 1989-05-01
ES2006438T3 true ES2006438T3 (es) 1993-10-01

Family

ID=13854300

Family Applications (1)

Application Number Title Priority Date Filing Date
ES198888105418T Expired - Lifetime ES2006438T3 (es) 1987-04-06 1988-04-05 Aparato para analisis automatico.

Country Status (3)

Country Link
EP (1) EP0289789B1 (es)
JP (1) JPH0634932B2 (es)
ES (1) ES2006438T3 (es)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
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US5166889A (en) * 1989-01-10 1992-11-24 Medical Robotics, Inc. Robotic liquid sampling system
DE3922333A1 (de) * 1989-07-07 1991-01-17 Buehler Edmund Gmbh & Co Probenentnahmegeraet mit automatischer selbstentleerung
DE3923833C2 (de) * 1989-07-19 1998-07-02 Boehringer Mannheim Gmbh Analysegerät für heterogene immunologische Tests
FR2672129B1 (fr) * 1990-11-16 1994-04-08 Alcyon Analyser Sa Machine pour realiser des analyses d'un materiau biologique a partir de prelevements du dit materiau et de reactif.
FR2669428B1 (fr) * 1990-11-16 1993-04-23 Alcyon Analyzer Sa Analyseur automatique d'echantillons par colorimetrie.
CA2384519C (en) * 1991-03-04 2006-08-15 Bayer Corporation Automated analyzer
JP3193443B2 (ja) * 1992-04-24 2001-07-30 オリンパス光学工業株式会社 自動分析装置
JP3111027B2 (ja) * 1995-08-22 2000-11-20 キヤノン株式会社 インク吐出量測定方法及びその装置
JP3063584B2 (ja) * 1995-09-05 2000-07-12 株式会社日立製作所 自動分析装置
US5807523A (en) * 1996-07-03 1998-09-15 Beckman Instruments, Inc. Automatic chemistry analyzer
WO1998009172A1 (fr) * 1996-08-30 1998-03-05 Optimum Research Procede de dosage de proteines et systeme pour sa mise en oeuvre
FR2801108B1 (fr) * 1999-11-16 2002-03-01 Maxmat S A Analyseur chimique ou biochimique a regulation de la temperature reactionnelle
US6489094B2 (en) * 2000-05-31 2002-12-03 Pfizer Inc. Method and device for drug-drug interaction testing sample preparation
US6627156B1 (en) 2000-06-22 2003-09-30 Beckman Coulter, Inc. Cap piercing station for closed container sampling system
US7217391B2 (en) * 2001-03-16 2007-05-15 Beckman Coulter, Inc. Rotary incubation station for immunoassay systems
GB0303453D0 (en) * 2003-02-14 2003-03-19 Thermo Clinical Labsystems Oy Automated sample analyzer and cuvette
EP1653234A1 (de) * 2004-10-27 2006-05-03 Roche Diagnostics GmbH Carouselartige Probeentnahmestation
JP2007212211A (ja) * 2006-02-08 2007-08-23 Juki Corp 分注装置の試薬置場
CN200960457Y (zh) 2006-10-26 2007-10-17 深圳迈瑞生物医疗电子股份有限公司 固体直热反应盘结构
CN101419240B (zh) 2007-10-23 2013-07-17 深圳迈瑞生物医疗电子股份有限公司 样本分析装置和样本分析方法
CN101419156B (zh) 2007-10-23 2012-12-05 深圳迈瑞生物医疗电子股份有限公司 分光光度检测方法与装置以及检测系统
KR101416694B1 (ko) * 2008-06-11 2014-07-09 삼성전자 주식회사 회전 가능한 미세유동 디스크를 이용한 시료 분석 장치
JP5414491B2 (ja) * 2009-12-02 2014-02-12 株式会社東芝 自動分析装置
JP4919119B2 (ja) * 2010-01-19 2012-04-18 株式会社日立プラントテクノロジー 試薬分注ノズルによる分取・分注方法および試薬分取・分注機構
CN102221604B (zh) 2010-04-14 2014-05-07 深圳迈瑞生物医疗电子股份有限公司 一种生化分析仪样本盘
JP5680383B2 (ja) * 2010-11-22 2015-03-04 株式会社東芝 自動分析装置
US8999241B2 (en) * 2011-03-16 2015-04-07 Sysmex Corporation Specimen analyzer
JP5134130B1 (ja) 2011-09-09 2013-01-30 シャープ株式会社 粒子検出装置
JP6047393B2 (ja) * 2012-12-17 2016-12-21 株式会社日立ハイテクノロジーズ 試薬保管庫および試薬保管庫を備えた自動分析装置
ES2905353T3 (es) * 2013-03-15 2022-04-08 Abbott Lab Gestor de reactivos automatizado de un sistema analizador de diagnóstico
WO2014171346A1 (ja) 2013-04-18 2014-10-23 株式会社日立ハイテクノロジーズ 自動分析装置
CN106918715B (zh) * 2017-04-27 2019-02-15 南京诺尔曼生物技术有限公司 一种化学发光诊断装置及其系统
CN109580595B (zh) * 2017-09-29 2024-05-14 深圳市新产业生物医学工程股份有限公司 化学发光检测仪、温育装置及反应盘机构
DE112017007781T5 (de) 2017-10-31 2020-04-23 Hitachi High-Technologies Corporation Abgabevorrichtung und Probenanalysevorrichtung
CN109856417B (zh) * 2019-04-04 2024-06-25 安图实验仪器(郑州)有限公司 新型自动微量加样装置
JP6995085B2 (ja) * 2019-05-31 2022-01-14 日本電子株式会社 自動分析装置及び自動分析装置の制御方法
CN112684127B (zh) * 2020-12-21 2024-02-13 江苏万略医药科技有限公司 一种生物类新药pkpd分析方法及分析装置
CN114236129B (zh) * 2021-12-20 2022-09-23 江苏集萃中科纳米科技有限公司 一种体外免疫诊断试剂背景发光处理系统
CN115447886B (zh) * 2022-08-01 2023-08-25 广州谱优峰科技有限公司 一种总淀粉检测试剂盒及其检测方法
CN116026821B (zh) * 2023-02-22 2023-12-12 深圳市深信信息技术有限公司 一种农产品智能检测方法及检测设备
CN117517124B (zh) * 2023-11-16 2024-03-26 四川省产品质量监督检验检测院 一种用于白酒固形物批量检测的装置

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US4169125A (en) * 1977-04-14 1979-09-25 Baxter Travenol Laboratories, Inc. Modular chemical analysis system
WO1982003462A1 (en) * 1981-03-27 1982-10-14 Ltd Biospecia Immunological analysis and a biochemical agent therefore
JPS60241884A (ja) * 1984-05-15 1985-11-30 Tokyo Daigaku 自動サイクリング反応装置およびこれを用いる自動分析装置
EP0216026B1 (en) * 1985-06-26 1992-01-22 Japan Tectron Instruments Corporation Automatic analysis apparatus

Also Published As

Publication number Publication date
EP0289789B1 (en) 1993-02-17
ES2006438A4 (es) 1989-05-01
JPS63248451A (ja) 1988-10-14
JPH0634932B2 (ja) 1994-05-11
EP0289789A1 (en) 1988-11-09

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