ES2002023A6 - Procedimiento para la fabricacion de derivados de 9-(tio-substituido)-4h-pirido(1,2-a)pirimidin-4-ona - Google Patents
Procedimiento para la fabricacion de derivados de 9-(tio-substituido)-4h-pirido(1,2-a)pirimidin-4-onaInfo
- Publication number
- ES2002023A6 ES2002023A6 ES8602449A ES8602449A ES2002023A6 ES 2002023 A6 ES2002023 A6 ES 2002023A6 ES 8602449 A ES8602449 A ES 8602449A ES 8602449 A ES8602449 A ES 8602449A ES 2002023 A6 ES2002023 A6 ES 2002023A6
- Authority
- ES
- Spain
- Prior art keywords
- optionally substituted
- pyrido
- pyrimidin
- derivatives
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
PROCEDIMIENTO PARA LA FABRICACION DE DERIVADOS DE 9-(TIO SUBSTITUIDO)-4H-PIRIDO 1,2-A PIRIMIDIN-4-ONA DE FORMULA: QUE COMPRENDE LA REACCION DEL COMPUESTO CON UN COMPUESTO ACILANTE DE FORMULA R1COX, A UNA TEMPERATURA COMPRENDIDA APROXIMADAMENTE ENTRE 0JC Y 80JC, PREFERENTEMENTE A TEMPERATURA AMBIENTE EN PRESENCIA DE UNA BASE EN UN DISOLVENTE, LA ACILACION CON EL ACIDO CARBOXILICO SE PUEDE OBTENER CONDUCIENDO LA REACCION EN PRESENCIA DE UN AGENTE DESHIDRATANTE TAL COMO DCC O SIMILAR EN UN DISOLVENTE, ADEMAS SE PUEDE REALIZAR LA ACILACION CON EL ACIDO CARBOXILICO Y CLOROCARBONATO-TRIETILAMINA ALQUILO INFERIOR EN UN DISOLVENTE ENTRE 0JC Y 100JC.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP21318185 | 1985-09-25 | ||
JP1159186 | 1986-01-21 | ||
JP18115986 | 1986-07-30 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2002023A6 true ES2002023A6 (es) | 1988-07-01 |
Family
ID=27279485
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES8602449A Expired ES2002023A6 (es) | 1985-09-25 | 1986-09-25 | Procedimiento para la fabricacion de derivados de 9-(tio-substituido)-4h-pirido(1,2-a)pirimidin-4-ona |
Country Status (10)
Country | Link |
---|---|
US (1) | US4840953A (es) |
EP (1) | EP0218423B1 (es) |
KR (1) | KR930009011B1 (es) |
CN (1) | CN1013447B (es) |
AU (1) | AU588917B2 (es) |
CA (1) | CA1283411C (es) |
DE (1) | DE3670843D1 (es) |
DK (1) | DK169580B1 (es) |
ES (1) | ES2002023A6 (es) |
GB (1) | GB2181129B (es) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2668259B2 (ja) * | 1988-02-18 | 1997-10-27 | 塩野義製薬株式会社 | 複素環化合物および抗潰瘍剤 |
US8785452B2 (en) * | 2008-06-17 | 2014-07-22 | Institut National De La Sante Et De La Recherche Medicale | Anti-infective compounds |
CA2771588C (en) * | 2009-09-09 | 2018-07-31 | E I Du Pont De Nemours And Company | Herbicidal pyrimidone derivatives |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3907798A (en) * | 1966-06-15 | 1975-09-23 | Sterling Drug Inc | Preparation of 4H-pyrido{8 1,2-a{9 pyrimidin-4-ones from cyclic alkylidene 2-pyridylaminomethylenemalonates |
AT302311B (de) * | 1966-11-02 | 1972-09-15 | Chinoin Gyogyszer Es Vegyeszet | Verfahren zur herstellung von homopyrimidazol-derivaten und deren saeureadditionssalzen und quaternaeren ammoniumsalzen |
US3960847A (en) * | 1972-04-17 | 1976-06-01 | E. R. Squibb & Sons, Inc. | 9-Substituted-4-oxopyrido(1,2-α)pyrimidine-3-carboxylic acids and derivatives thereof |
HU168541B (es) * | 1973-11-24 | 1976-05-28 | ||
US4022897A (en) * | 1974-03-04 | 1977-05-10 | E. R. Squibb & Sons, Inc. | CNS active compounds |
US4122274A (en) * | 1977-05-25 | 1978-10-24 | Bristol-Myers Company | 3-Tetrazolo-5,6,7,8-substituted-pyrido[1,2-a]pyrimidin-4-ones |
US4209620A (en) * | 1978-06-19 | 1980-06-24 | Bristol-Myers Company | Substituted 3-(1H-tetrazol-5-yl)-4H-pyrido[1,2-a]pyrimidin-4-one derivatives having antiallergy activity |
JPS5830760B2 (ja) * | 1980-10-09 | 1983-07-01 | 株式会社日立製作所 | プリント回路板の製法 |
US4457932A (en) * | 1983-07-22 | 1984-07-03 | Bristol-Myers Company | Anti-ulcer agents |
-
1986
- 1986-09-24 AU AU63104/86A patent/AU588917B2/en not_active Ceased
- 1986-09-24 DK DK456986A patent/DK169580B1/da active
- 1986-09-24 CA CA000519033A patent/CA1283411C/en not_active Expired - Fee Related
- 1986-09-25 CN CN86106902A patent/CN1013447B/zh not_active Expired
- 1986-09-25 GB GB8623116A patent/GB2181129B/en not_active Expired
- 1986-09-25 EP EP86307404A patent/EP0218423B1/en not_active Expired - Lifetime
- 1986-09-25 KR KR1019860008029A patent/KR930009011B1/ko not_active IP Right Cessation
- 1986-09-25 ES ES8602449A patent/ES2002023A6/es not_active Expired
- 1986-09-25 DE DE8686307404T patent/DE3670843D1/de not_active Expired - Fee Related
-
1988
- 1988-06-15 US US07/206,665 patent/US4840953A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
DK169580B1 (da) | 1994-12-12 |
AU588917B2 (en) | 1989-09-28 |
DK456986D0 (da) | 1986-09-24 |
EP0218423A2 (en) | 1987-04-15 |
DE3670843D1 (de) | 1990-06-07 |
CN1013447B (zh) | 1991-08-07 |
KR870003105A (ko) | 1987-04-15 |
CA1283411C (en) | 1991-04-23 |
EP0218423A3 (en) | 1988-01-20 |
US4840953A (en) | 1989-06-20 |
AU6310486A (en) | 1987-03-26 |
KR930009011B1 (ko) | 1993-09-18 |
GB2181129B (en) | 1989-09-20 |
GB8623116D0 (en) | 1986-10-29 |
CN86106902A (zh) | 1987-06-10 |
GB2181129A (en) | 1987-04-15 |
EP0218423B1 (en) | 1990-05-02 |
DK456986A (da) | 1987-03-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 20000601 |