EP4716533A2 - Fluoreszenzindikatoren zur detektion von metallionen als substrate für ein selbstmarkierungsenzym - Google Patents

Fluoreszenzindikatoren zur detektion von metallionen als substrate für ein selbstmarkierungsenzym

Info

Publication number
EP4716533A2
EP4716533A2 EP24811949.7A EP24811949A EP4716533A2 EP 4716533 A2 EP4716533 A2 EP 4716533A2 EP 24811949 A EP24811949 A EP 24811949A EP 4716533 A2 EP4716533 A2 EP 4716533A2
Authority
EP
European Patent Office
Prior art keywords
compound
group
independently represent
nhr
counter cation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP24811949.7A
Other languages
English (en)
French (fr)
Inventor
Miguel Angel MACIAS-CONTRERAS
Jessica Patricia GRANADOS
Pedro Rogelio Escamilla
Derek Scott HERNANDEZ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ion Biosciences
Original Assignee
Ion Biosciences
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ion Biosciences filed Critical Ion Biosciences
Publication of EP4716533A2 publication Critical patent/EP4716533A2/de
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/10—Spiro-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78—Ring systems having three or more relevant rings
    • C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
    • C07D311/82—Xanthenes
    • C07D311/90—Xanthenes with hydrocarbon radicals, substituted by amino radicals, directly attached in position 9
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
EP24811949.7A 2023-05-23 2024-05-23 Fluoreszenzindikatoren zur detektion von metallionen als substrate für ein selbstmarkierungsenzym Pending EP4716533A2 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US202363503873P 2023-05-23 2023-05-23
US202363514500P 2023-07-19 2023-07-19
US202363613281P 2023-12-21 2023-12-21
PCT/US2024/030898 WO2024243471A2 (en) 2023-05-23 2024-05-23 Fluorescent indicators for metal ion detection as substrates for a self-labeling enzyme

Publications (1)

Publication Number Publication Date
EP4716533A2 true EP4716533A2 (de) 2026-04-01

Family

ID=93590408

Family Applications (1)

Application Number Title Priority Date Filing Date
EP24811949.7A Pending EP4716533A2 (de) 2023-05-23 2024-05-23 Fluoreszenzindikatoren zur detektion von metallionen als substrate für ein selbstmarkierungsenzym

Country Status (2)

Country Link
EP (1) EP4716533A2 (de)
WO (1) WO2024243471A2 (de)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9810700B1 (en) * 2017-05-31 2017-11-07 Aat Bioquest, Inc. Fluorogenic calcium ion indicators and methods of using the same

Also Published As

Publication number Publication date
WO2024243471A2 (en) 2024-11-28
WO2024243471A3 (en) 2025-04-10

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