EP4211197A1 - Procédé de traitement d'une surface, et utilisation d'un hydrolysat de collagène pour traiter une surface - Google Patents

Procédé de traitement d'une surface, et utilisation d'un hydrolysat de collagène pour traiter une surface

Info

Publication number
EP4211197A1
EP4211197A1 EP21748797.4A EP21748797A EP4211197A1 EP 4211197 A1 EP4211197 A1 EP 4211197A1 EP 21748797 A EP21748797 A EP 21748797A EP 4211197 A1 EP4211197 A1 EP 4211197A1
Authority
EP
European Patent Office
Prior art keywords
treatment solution
microorganisms
collagen hydrolyzate
collagen
treating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP21748797.4A
Other languages
German (de)
English (en)
Inventor
Berthold Köhler
Matthias Reihmann
Peter Reiter
Nina RITTEREISER
Ceren Yüce
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gelita AG
Original Assignee
Gelita AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gelita AG filed Critical Gelita AG
Publication of EP4211197A1 publication Critical patent/EP4211197A1/fr
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09D—COATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
    • C09D189/00—Coating compositions based on proteins; Coating compositions based on derivatives thereof
    • C09D189/04—Products derived from waste materials, e.g. horn, hoof or hair
    • C09D189/06—Products derived from waste materials, e.g. horn, hoof or hair derived from leather or skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/16—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
    • A61L2/18—Liquid substances or solutions comprising solids or dissolved gases
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09D—COATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
    • C09D5/00—Coating compositions, e.g. paints, varnishes or lacquers, characterised by their physical nature or the effects produced; Filling pastes
    • C09D5/14—Paints containing biocides, e.g. fungicides, insecticides or pesticides
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09D—COATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
    • C09D5/00—Coating compositions, e.g. paints, varnishes or lacquers, characterised by their physical nature or the effects produced; Filling pastes
    • C09D5/16—Antifouling paints; Underwater paints
    • C09D5/1606—Antifouling paints; Underwater paints characterised by the anti-fouling agent
    • C09D5/1637—Macromolecular compounds

Definitions

  • the present invention relates to a method of treating a surface to improve the removability of microorganisms from the surface.
  • microorganisms in particular with bacteria and viruses
  • contamination of surfaces with microorganisms is a problem in various areas of daily life and in industry, because diseases can be transmitted by a large number of pathogenic microorganisms by means of smear infection, or because food can be contaminated by contact with a such surface can be contaminated.
  • cleaning with water or surfactants cannot, or only partially, remove, kill or inactivate microorganisms on surfaces.
  • biocides are often used as disinfectants to reduce the contamination of surfaces with microorganisms.
  • Various chemical compounds having biocidal (e.g. bactericidal) activity are known, including, for example, alcohols, isothiazolinones, quaternary ammonium compounds and formaldehyde-releasing compounds.
  • biocidal activity e.g. bactericidal
  • alcohols e.g. alcohols
  • isothiazolinones e.g. quaternary ammonium compounds
  • formaldehyde-releasing compounds e.g. bactericidal
  • the use of such disinfectants especially if they are used frequently, can be problematic or undesirable with regard to health risks (e.g. due to contact allergies) or with regard to environmental pollution.
  • the disinfectants mentioned only have a one-time effect in the respective application.
  • surface treatment agents against microorganisms with a long-term effect are known, such as colloidal or nanoparticulate silver, certain copper compounds or nanoparticulate titanium dioxide.
  • colloidal or nanoparticulate silver, certain copper compounds or nanoparticulate titanium dioxide are known, such as colloidal or nanoparticulate silver, certain copper compounds or nanoparticulate titanium dioxide.
  • these substances are even more problematic in terms of health risks, and in the case of titanium dioxide, plastic surfaces can also be attacked due to the mechanism of action (formation of radicals by UV light).
  • the invention is based on the object of proposing a method by the use of which the contamination of surfaces by microorganisms can be reduced in a simple manner over the longer term.
  • the treatment solution comprising an aqueous solution of a collagen hydrolyzate
  • microorganisms can be removed more easily from a surface treated according to the invention, which is contaminated with microorganisms after treatment, than from an untreated surface.
  • the method according to the invention means that a larger proportion of the microorganisms can be removed again just by rinsing with water than with an untreated surface.
  • the applied collagen hydrolyzate forms a hydrophilic layer on the treated surface, which is typically a few nanometers thick. Since collagen hydrolyzate as a protein represents a potential nutrient substrate for microorganisms, it is quite surprising that the method according to the invention contributes to being able to remove microorganisms more easily from surfaces. Without being bound to a theory, the inventors assume that adhesion of microorganisms to the collagen hydrolyzate layer, which swells in the presence of water, is made more difficult, see above that cleaning with water (or a cleaning agent) is made easier. Furthermore, during the subsequent cleaning, parts of the layer could become detached together with the microorganisms.
  • the method according to the invention can thus contribute to at least reducing the use of chemical disinfectants (biocides) when cleaning surfaces.
  • Collagen hydrolyzate that is used within the scope of the method according to the invention is a degradation product of the animal connective tissue protein collagen.
  • collagen hydrolyzate is water-soluble even at room temperature due to its lower molecular weight and does not form a gel.
  • the collagen hydrolyzate is preferably produced by enzymatic hydrolysis of a collagen-containing starting material.
  • microbial or plant endopeptidases and exopeptidases can be used for the hydrolysis.
  • the molecular weight of the collagen hydrolyzate produced can be influenced by the selection of the peptidases and the hydrolysis conditions.
  • the collagen-containing starting material is usually selected from the skin or bones of vertebrates, in particular cattle or pigs. However, the use of starting materials from other mammals, birds or fish is also conceivable.
  • the collagen hydrolyzate can be produced within the scope of the invention by recombinant gene expression.
  • natural collagen sequences in particular from cattle or pigs, and their expression in genetically modified cells (e.g. yeasts, bacteria or plant cells, in particular tobacco)
  • products can be produced which, with the hydrolysis products of the corresponding collagen-containing raw materials are essentially identical. In this way it is possible to obtain a narrower or precisely specified molecular weight distribution.
  • the collagen hydrolyzate preferably has an average molecular weight of from about 1000 to about 7000 Da, more preferably from about 2000 to about 5000 Da. This information relates to the weight-average molecular weight, which is determined by means of gel permeation chromatography. As already mentioned, collagen hydrolysates in this molecular weight range have good solubility in cold water.
  • the treatment solution preferably comprises from about 0.5% to about 8% by weight of the collagen hydrolyzate, more preferably from about 2% to about 6% by weight.
  • the treatment solution is applied to the surface in an amount of about 10 to about 50 ml/m 2 , more preferably in an amount of about 20 to about 30 ml/m 2 .
  • the treatment solution can be brushed onto the surface, e.g. with a sponge or cloth, or sprayed onto the surface.
  • microorganisms whose removability can be improved by the method according to the invention include, in particular, bacteria, fungi, algae and viruses. Although the latter are not living beings according to the prevailing view, they are often included under the generic term of microorganisms, including within the scope of the present invention. All types of microorganisms mentioned contain pathogens or can lead to spoilage of food that comes into contact with a contaminated surface.
  • the microorganisms are bacteria, in particular faecal bacteria such as Escherichia coli.
  • the treatment solution contains no biocides. Biocides are not required for the basic mode of operation of the process, since the removability of the microorganisms with water or a cleaning agent is already improved.
  • a treatment solution can be used according to the invention which, in addition to the collagen hydrolyzate, does not include any other active substances, in particular no surfactants. Such a treatment solution is completely safe from a health and ecological point of view and can therefore be used frequently. This can then be combined with the use of a disinfectant at longer intervals.
  • the treatment solution comprises further active substances which are preferably selected from biocides, in particular bactericides, surfactants, phosphates, preservatives, fragrances and/or auxiliaries.
  • the collagen hydrolyzate is in principle added to a common cleaning agent or disinfectant.
  • the method according to the invention can be used on all surfaces, preferably smooth surfaces.
  • the method is particularly suitable for treating surfaces made of glass, plastic or metal.
  • the method according to the invention can be used in a wide variety of areas, for example in the home, in industry and in public transport.
  • the surface to be treated is in particular a surface of furniture, furnishings, walls, floors or vehicles.
  • the method according to the invention can also be used in areas in which food, drinking water or other products in which contamination with microorganisms is to be avoided are in contact with a surface.
  • the surface to be treated is in particular an inner surface of containers or pipelines.
  • the invention further relates to the use of collagen hydrolyzate to treat a surface to improve the removability of microorganisms from the surface.
  • FIG. 1 to 8 Micrographs of E. coli bacteria
  • the treatment solution or water was then allowed to air dry on all eight slides.
  • a small amount of a colony was removed from a pure-strain dish of E. coli using a sterile inoculation loop and suspended in 5 ml of sterile tap water. 0.5 ⁇ l of this germ suspension were dropped 3 times onto each of the eight slides, the suspension being homogenized again with a vortex mixer before coating a slide. The germ suspension was then air-dried on the slides for a period of 17 hours.
  • slides #2 and #6 were immersed in a beaker filled with distilled water for 30 seconds and slides #4 and #8 for 60 seconds, and then air-dried again. Slides #1, 3, 5, and 7 were untreated in this regard.
  • Figures 1 through 8 show photomicrographs of fixed and stained slides #1 through #8, respectively, at 100X magnification.
  • the first thing that is striking is the different drying behavior of the germ suspension on slides nos. 5 to 8 treated according to the invention compared to slides nos. 1 to 4, which were previously only treated with water. While the drop on the untreated slides dries from the outside in, with concentric Rings of bacteria form, the germ suspension dries very homogeneously on the slides coated with collagen hydrolyzate. This makes it difficult to directly compare the germ counts, for example using automatic image analysis.
  • the microscopic images were therefore digitized and the number of bacteria within an identical area inside the drops was determined several times using image analysis software. Based on the data obtained in this way, the percentage reduction in the number of bacteria caused by the respective washing process (immersion in water) compared to an unwashed slide was determined.
  • a comparison of the values shows that removing bacteria from the glass surface by immersing the slide in water is significantly more effective is when the surface has been treated with collagen hydrolyzate prior to application of the bacteria.

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Plant Pathology (AREA)
  • Application Of Or Painting With Fluid Materials (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Detergent Compositions (AREA)
  • Peptides Or Proteins (AREA)

Abstract

La présente invention concerne un procédé de traitement d'une surface dans le but d'améliorer la possibilité d'enlever de la surface des micro-organismes, le procédé comprenant les étapes suivantes : - application d'une solution de traitement à la surface, la solution de traitement comprenant une solution aqueuse d'un hydrolysat de collagène ; et – le fait de laisser la surface sécher. L'invention porte également sur l'utilisation d'un hydrolysat de collagène pour traiter une surface dans le but d'améliorer la possibilité d'enlever de la surface des micro-organismes.
EP21748797.4A 2020-09-11 2021-07-08 Procédé de traitement d'une surface, et utilisation d'un hydrolysat de collagène pour traiter une surface Pending EP4211197A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102020123736.7A DE102020123736A1 (de) 2020-09-11 2020-09-11 Verfahren zur Behandlung einer Oberfläche und Verwendung von Kollagenhydrolysat zur Behandlung einer Oberfläche
PCT/EP2021/068937 WO2022053201A1 (fr) 2020-09-11 2021-07-08 Procédé de traitement d'une surface, et utilisation d'un hydrolysat de collagène pour traiter une surface

Publications (1)

Publication Number Publication Date
EP4211197A1 true EP4211197A1 (fr) 2023-07-19

Family

ID=77155737

Family Applications (1)

Application Number Title Priority Date Filing Date
EP21748797.4A Pending EP4211197A1 (fr) 2020-09-11 2021-07-08 Procédé de traitement d'une surface, et utilisation d'un hydrolysat de collagène pour traiter une surface

Country Status (7)

Country Link
US (1) US20230212427A1 (fr)
EP (1) EP4211197A1 (fr)
CN (1) CN116057129A (fr)
AR (1) AR123418A1 (fr)
AU (1) AU2021341356A1 (fr)
DE (1) DE102020123736A1 (fr)
WO (1) WO2022053201A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102022119507A1 (de) * 2022-08-03 2024-02-08 Gelita Ag Verfahren zur Herstellung eines Papiers mit einer verbesserten Fett- und Öldichtigkeit, hergestelltes Papier und dessen Verwendung

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4762768A (en) 1986-01-29 1988-08-09 Macdermid, Incorporated Thermally stabilized photoresist images
DE102005036688A1 (de) 2005-08-04 2007-02-08 Kalle Gmbh Imprägnierte oder beschichtete schlauchförmige Nahrungsmittelhülle auf Cellulosebasis
DE102005044321A1 (de) 2005-09-16 2007-03-29 Kalle Gmbh Pigmentierter und innenimprägnierter Cellulose-Faserdarm
WO2010001149A2 (fr) * 2008-07-04 2010-01-07 Fujifilm Manufacturing Europe Bv Procédé de revêtement pour dispositifs médicaux
US10821085B2 (en) 2010-12-07 2020-11-03 Kimberly-Clark Worldwide, Inc. Wipe coated with a botanical composition having antimicrobial properties
CN107984841A (zh) * 2017-11-02 2018-05-04 湖北德威包装科技有限公司 一种耐低温防起雾蒸煮膜及其制备方法

Also Published As

Publication number Publication date
WO2022053201A1 (fr) 2022-03-17
US20230212427A1 (en) 2023-07-06
AU2021341356A1 (en) 2023-03-23
DE102020123736A1 (de) 2022-03-17
CN116057129A (zh) 2023-05-02
AR123418A1 (es) 2022-11-30

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