EP4151315A1 - Centrifugeuse et procédé de nettoyage d'une centrifugeuse - Google Patents

Centrifugeuse et procédé de nettoyage d'une centrifugeuse Download PDF

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Publication number
EP4151315A1
EP4151315A1 EP22196177.4A EP22196177A EP4151315A1 EP 4151315 A1 EP4151315 A1 EP 4151315A1 EP 22196177 A EP22196177 A EP 22196177A EP 4151315 A1 EP4151315 A1 EP 4151315A1
Authority
EP
European Patent Office
Prior art keywords
rotor
cleaning solution
centrifuge
space
cleaning
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP22196177.4A
Other languages
German (de)
English (en)
Inventor
Dr. Wolfgang Mann
Frank FEIST
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bluecatbio GmbH
Original Assignee
Bluecatbio GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bluecatbio GmbH filed Critical Bluecatbio GmbH
Publication of EP4151315A1 publication Critical patent/EP4151315A1/fr
Pending legal-status Critical Current

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L13/00—Cleaning or rinsing apparatus
    • B01L13/02—Cleaning or rinsing apparatus for receptacle or instruments
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B15/00—Other accessories for centrifuges
    • B04B15/06—Other accessories for centrifuges for cleaning bowls, filters, sieves, inserts, or the like
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B5/00—Other centrifuges
    • B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
    • B04B5/0407—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers for liquids contained in receptacles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B7/00—Elements of centrifuges
    • B04B7/02—Casings; Lids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B08—CLEANING
    • B08B—CLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
    • B08B3/00—Cleaning by methods involving the use or presence of liquid or steam
    • B08B3/003—Cleaning involving contact with foam
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B08—CLEANING
    • B08B—CLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
    • B08B3/00—Cleaning by methods involving the use or presence of liquid or steam
    • B08B3/04—Cleaning involving contact with liquid
    • B08B3/10—Cleaning involving contact with liquid with additional treatment of the liquid or of the object being cleaned, e.g. by heat, by electricity or by vibration
    • B08B3/102—Cleaning involving contact with liquid with additional treatment of the liquid or of the object being cleaned, e.g. by heat, by electricity or by vibration with means for agitating the liquid
    • B08B3/104—Cleaning involving contact with liquid with additional treatment of the liquid or of the object being cleaned, e.g. by heat, by electricity or by vibration with means for agitating the liquid using propellers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B08—CLEANING
    • B08B—CLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
    • B08B9/00—Cleaning hollow articles by methods or apparatus specially adapted thereto 
    • B08B9/08—Cleaning containers, e.g. tanks
    • B08B9/0804—Cleaning containers having tubular shape, e.g. casks, barrels, drums
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B08—CLEANING
    • B08B—CLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
    • B08B9/00—Cleaning hollow articles by methods or apparatus specially adapted thereto 
    • B08B9/08—Cleaning containers, e.g. tanks
    • B08B9/0821—Handling or manipulating containers, e.g. moving or rotating containers in cleaning devices, conveying to or from cleaning devices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B08—CLEANING
    • B08B—CLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
    • B08B9/00—Cleaning hollow articles by methods or apparatus specially adapted thereto 
    • B08B9/08—Cleaning containers, e.g. tanks
    • B08B9/20—Cleaning containers, e.g. tanks by using apparatus into or on to which containers, e.g. bottles, jars, cans are brought
    • B08B9/28—Cleaning containers, e.g. tanks by using apparatus into or on to which containers, e.g. bottles, jars, cans are brought the apparatus cleaning by splash, spray, or jet application, with or without soaking
    • B08B9/34—Arrangements of conduits or nozzles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B08—CLEANING
    • B08B—CLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
    • B08B9/00—Cleaning hollow articles by methods or apparatus specially adapted thereto 
    • B08B9/08—Cleaning containers, e.g. tanks
    • B08B9/20—Cleaning containers, e.g. tanks by using apparatus into or on to which containers, e.g. bottles, jars, cans are brought
    • B08B9/42—Cleaning containers, e.g. tanks by using apparatus into or on to which containers, e.g. bottles, jars, cans are brought the apparatus being characterised by means for conveying or carrying containers therethrough
    • B08B9/44—Cleaning containers, e.g. tanks by using apparatus into or on to which containers, e.g. bottles, jars, cans are brought the apparatus being characterised by means for conveying or carrying containers therethrough the means being for loading or unloading the apparatus
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0829—Multi-well plates; Microtitration plates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0409—Moving fluids with specific forces or mechanical means specific forces centrifugal forces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B08—CLEANING
    • B08B—CLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
    • B08B2209/00—Details of machines or methods for cleaning hollow articles
    • B08B2209/08—Details of machines or methods for cleaning containers, e.g. tanks

Definitions

  • U.S. 4,953,575 relates to a washing device for cuvettes.
  • the cuvettes are placed in a holder in a rotor.
  • the liquid is removed from the cuvettes by turning the rotor.
  • the disclosed centrifuge housing has an opening at its lowest point through which the removed liquid can leave the housing.
  • the JP 2007/178355 A discloses a system for cleaning printed circuit boards in which one or more microtiter plates are placed in a rotary unit whose axis of rotation is vertical.
  • the device has a number of nozzles which can spray the microtiter plates with a cleaning liquid from the outside.
  • a cleaning solution can thus be supplied to this centrifuge and distributed in the rotor space.
  • the rotor is used to distribute the cleaning solution. This is discussed further below in explaining the procedure for cleaning the centrifuge.
  • the inlet can be arranged above an axis of rotation of the rotor, so that when the cleaning solution is fed in, it can come into contact with the rotor.
  • the rotor can of course be in a position where it does not come into contact with the cleaning solution fed by the inlet, for example when it is oriented vertically.
  • a cleaning liquid supplied in this way is carried along by a rotating, in particular rapidly rotating, rotor and is distributed in the rotor chamber. Low speeds of a few rpm are already sufficient for this.
  • the rotor is rotated at speeds of at least 10 rpm or at least 50 rpm or more.
  • the inlet can also have one or more nozzles in order to atomize the cleaning solution into the rotor space.
  • a cleaning liquid which is atomized in the rotor space in this way can also be distributed uniformly in the rotor space by turning the rotor.
  • the air flow generated by the rotor when rotating is lowest in this area, so that liquid can settle on the bottom of the funnel, i.e. in the trough 22, and flow out of the Channel 22 flows out through the outlet opening 23. Because of the low flow rate, there is also little risk of liquids located in the funnel-shaped area adjacent to the channel 22 being driven upwards by the air flow.
  • the balcony 18 is formed in the area below the dispensing unit 30 with a channel 33 which is open at the top and in which the reagents dispensed by the dispensing nozzles 31 are collected if no reaction vessel unit 7 is arranged below the dispensing nozzles 31, as is the case in Figure 4a is shown.
  • the channel 33 communicates with a collecting tube 34 so that the reagents collected in the channel 33 flow off via the collecting tube 34 .
  • the collecting hose 34 opens into the hose 25 at a branch 35. With regard to the rotor chamber 9, starting from the branch 35, the collecting hose forms an inlet line and the hose 25 forms an outlet line for discharging liquids from the rotor chamber 9.
  • the rotor space 9 is at least filled up to a level 43, as is the case figure 2 is shown.
  • the level 43 is about 5% of the radius of the rotor 2 and preferably at least 10% of the radius of the rotor 2 above the level 29, which is just not touched when the rotor 2 rotates.
  • Such a defoaming solution may contain, for example, alcohol.
  • a solution containing alcohol also has the advantage that it evaporates very quickly and the rotor space 9 dries accordingly quickly as a result.
  • an atomizing nozzle 40 in the feed opening 39 . This depends on the dimensions of the rotor space, the rotor and the air flow generated thereby during the turning of the rotor. Adequate distribution of the cleaning solution can thus be achieved simply by turning the rotor and the air flow generated thereby, without the need for atomizing nozzles.

Landscapes

  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Centrifugal Separators (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Cleaning By Liquid Or Steam (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
EP22196177.4A 2021-09-16 2022-09-16 Centrifugeuse et procédé de nettoyage d'une centrifugeuse Pending EP4151315A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE102021124023.9A DE102021124023A1 (de) 2021-09-16 2021-09-16 Zentrifuge und Verfahren zum Reinigen einer Zentrifuge

Publications (1)

Publication Number Publication Date
EP4151315A1 true EP4151315A1 (fr) 2023-03-22

Family

ID=83361094

Family Applications (1)

Application Number Title Priority Date Filing Date
EP22196177.4A Pending EP4151315A1 (fr) 2021-09-16 2022-09-16 Centrifugeuse et procédé de nettoyage d'une centrifugeuse

Country Status (5)

Country Link
US (1) US20230077651A1 (fr)
EP (1) EP4151315A1 (fr)
JP (1) JP2023047313A (fr)
CN (1) CN115805145A (fr)
DE (1) DE102021124023A1 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102017113583A1 (de) * 2017-06-20 2018-12-20 Bluecatbio Gmbh Zentrifuge
DE102022102705A1 (de) 2022-02-04 2023-08-10 BlueCat Solutions GmbH Auffangvorrichtung für eine Reaktionsgefäßeinheit und Reaktionsgefäßeinheit
DE102022102701A1 (de) 2022-02-04 2023-08-10 Bluecatbio Gmbh Ableitvorrichtung für eine Reaktionsgefäßeinheit, Zentrifuge und Verfahren zum Reinigen einer Reaktionsgefäßeinheit

Citations (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2404036A1 (de) 1974-01-29 1975-07-31 Heraeus Christ Gmbh Zentrifuge zur behandlung biologischer fluessigkeiten wie blut
JPS5143967U (fr) * 1974-09-28 1976-03-31
US4953575A (en) 1988-09-30 1990-09-04 Labsystems Oy Washing device
EP0937502A2 (fr) 1997-12-15 1999-08-25 Wallac Oy Méthode et appareil pour manipuler les plaques porte-échantillons
EP1033446A1 (fr) 1999-03-04 2000-09-06 Gert Dr. Dallach Procédé de construction d'une structure de fondation dans une excavation remplie d'eau
DE10355179A1 (de) 2003-11-26 2005-06-30 Kendro Laboratory Products Gmbh Luftgekühlte Zentrifuge
US20070037684A1 (en) 2005-08-10 2007-02-15 Moscone Kenneth J Sr Centrifuge bucket design
JP2007178355A (ja) 2005-12-28 2007-07-12 Nippon Support System Kk 試薬廃棄装置
JP2009264927A (ja) 2008-04-25 2009-11-12 Micronics Kk マイクロプレート処理装置
CN102175855A (zh) 2011-01-13 2011-09-07 邱重任 一种全自动360度甩干的卧式酶标洗板机
EP2705903A1 (fr) 2012-09-06 2014-03-12 Eppendorf AG Dispositif à rotor, cuvette de centrifugation et centrifugeuse ainsi que leur procédé de fabrication
WO2015018878A2 (fr) 2013-08-06 2015-02-12 Yantai Ausbio Laboratories Co., Ltd. Centrifugeuse et procédé de centrifugation d'une unité de récipient de réaction
WO2017125598A1 (fr) 2016-01-22 2017-07-27 Bluecatbio Gmbh Centrifugeuse
WO2018234420A1 (fr) 2017-06-20 2018-12-27 Bluecatbio Gmbh Centrifugeuse
CN113000230A (zh) * 2021-02-24 2021-06-22 安徽中科中佳科学仪器有限公司 一种杀菌消毒自清洁的实验室医用离心机

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH615604A5 (fr) * 1977-02-22 1980-02-15 Escher Wyss Ag
DE3633528C2 (de) * 1986-10-02 1996-03-07 Duerr Dental Gmbh Co Kg Verfahren zum Messen der Mächtigkeit einer Feststoffschicht auf der Umfangswand einer Zentrifugentrommel und Vorrichtung zur Durchführung des Verfahrens
SE459234B (sv) * 1987-10-15 1989-06-19 Alfa Laval Marine Power Eng Saett och utrustning foer invaendig diskning av en centrifugrotor
JP3676346B2 (ja) * 2003-01-30 2005-07-27 月島機械株式会社 遠心分離機、遠心分離機の洗浄方法

Patent Citations (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2404036A1 (de) 1974-01-29 1975-07-31 Heraeus Christ Gmbh Zentrifuge zur behandlung biologischer fluessigkeiten wie blut
JPS5143967U (fr) * 1974-09-28 1976-03-31
US4953575A (en) 1988-09-30 1990-09-04 Labsystems Oy Washing device
EP0937502A2 (fr) 1997-12-15 1999-08-25 Wallac Oy Méthode et appareil pour manipuler les plaques porte-échantillons
EP1033446A1 (fr) 1999-03-04 2000-09-06 Gert Dr. Dallach Procédé de construction d'une structure de fondation dans une excavation remplie d'eau
DE10355179A1 (de) 2003-11-26 2005-06-30 Kendro Laboratory Products Gmbh Luftgekühlte Zentrifuge
US20070037684A1 (en) 2005-08-10 2007-02-15 Moscone Kenneth J Sr Centrifuge bucket design
JP2007178355A (ja) 2005-12-28 2007-07-12 Nippon Support System Kk 試薬廃棄装置
JP2009264927A (ja) 2008-04-25 2009-11-12 Micronics Kk マイクロプレート処理装置
CN102175855A (zh) 2011-01-13 2011-09-07 邱重任 一种全自动360度甩干的卧式酶标洗板机
EP2705903A1 (fr) 2012-09-06 2014-03-12 Eppendorf AG Dispositif à rotor, cuvette de centrifugation et centrifugeuse ainsi que leur procédé de fabrication
WO2015018878A2 (fr) 2013-08-06 2015-02-12 Yantai Ausbio Laboratories Co., Ltd. Centrifugeuse et procédé de centrifugation d'une unité de récipient de réaction
WO2017125598A1 (fr) 2016-01-22 2017-07-27 Bluecatbio Gmbh Centrifugeuse
DE102016101163A1 (de) 2016-01-22 2017-07-27 Bluecatbio Gmbh Zentrifuge
WO2018234420A1 (fr) 2017-06-20 2018-12-27 Bluecatbio Gmbh Centrifugeuse
CN113000230A (zh) * 2021-02-24 2021-06-22 安徽中科中佳科学仪器有限公司 一种杀菌消毒自清洁的实验室医用离心机

Also Published As

Publication number Publication date
US20230077651A1 (en) 2023-03-16
DE102021124023A1 (de) 2023-03-16
JP2023047313A (ja) 2023-04-05
CN115805145A (zh) 2023-03-17

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