EP4003010A1 - Nouvelle formulation à base d'un oléogel, en particulier permettant la libération de composants volatiles, et procédé permettant la fabrication de celui-ci - Google Patents

Nouvelle formulation à base d'un oléogel, en particulier permettant la libération de composants volatiles, et procédé permettant la fabrication de celui-ci

Info

Publication number
EP4003010A1
EP4003010A1 EP20746600.4A EP20746600A EP4003010A1 EP 4003010 A1 EP4003010 A1 EP 4003010A1 EP 20746600 A EP20746600 A EP 20746600A EP 4003010 A1 EP4003010 A1 EP 4003010A1
Authority
EP
European Patent Office
Prior art keywords
oleogel
liquid
formulation
hydrophilic
formulation according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP20746600.4A
Other languages
German (de)
English (en)
Inventor
Anant Patel
Linda MUSKAT
Pascal HUMBERT
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hochschule Bielefeld University Of Applied Sciences And Arts Hsbi
Original Assignee
Fachhochschule Bielefeld
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fachhochschule Bielefeld filed Critical Fachhochschule Bielefeld
Publication of EP4003010A1 publication Critical patent/EP4003010A1/fr
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/02—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing liquids as carriers, diluents or solvents
    • A01N25/04—Dispersions, emulsions, suspoemulsions, suspension concentrates or gels

Definitions

  • the present invention is directed to an oleogel formulation suitable for releasing volatile components such as semiochemicals; this formulation contains at least one oleogelator, such as alkyl cellulose, a volatile component and a non-polar liquid.
  • an oleogel formulation is provided containing an active ingredient comprising at least one oleogelator, the active ingredient and an unpolar liquid.
  • the present invention also relates to a process for producing the oleogel formulation according to the invention.
  • the use of the oleogel formulation according to the invention is described in particular as a plant protection agent and pest control agent, but also in the food or pharmaceutical industry, containing pharmaceutical or cosmetic active ingredients, flavors or fragrances.
  • WO 90/00005 describes microencapsulated pesticides with an attractant.
  • an attractant in an outer shell with an outer shell, while the core of this capsule contains a pesticide.
  • the insect is attracted by the attractant and when the capsule is pierced, the insect picks up a pesticide.
  • liquid core capsules for combating pests such as biting-sucking insects are known.
  • This liquid core capsule has an aqueous core and a diffusion-inhibiting outer shell. While the outer shell contains an attractant for the pest, the core contains a pest control agent.
  • This document describes the use of hydrogel casings as the outer material. Similar constructs can be found in EP 2 415 356 A2. Here, capsules with a solid shell are described, which have a diffusion barrier z. B. of ethyl cellulose and / or resin-based polymers.
  • WO 2015/073439 A1 describes liposomal attractant formulations comprising pesticides or nematicides.
  • oleogelator such as alkyl cellulose
  • volatile component such as volatile semiochemicals and
  • an oleogel formulation containing an active ingredient comprising
  • oleogelator such as alkyl cellulose
  • the oleogel capsule shell has advantages over both the bilayer structure of liposomes and over hydrogels as hydrophilic gels.
  • hydrophilic ingredients and components can be provided with the formulation according to the invention.
  • the oleogelators are a combination of alkyl cellulose and vegetable wax.
  • the combinations of Ethylcellu loose with vegetable wax, such as carnauba wax and candelilla wax, are particularly suitable, these being present in amounts of 0.1-20% and proportions of 2: 0.01 to 0.01: 2.
  • Suitable non-polar liquids include, in particular, those selected from vegetable, animal, microbial or mineral oils.
  • Suitable materials are e.g. B. sunflower oil, rapeseed oil, sesame oil, olive oil, linseed oil, corn oil, palm oil, soybean oil, cocoa butter, fish oil, paraffin oil, castor oil, nut oil, coconut oil, peanut oil, palk kernel oil, cottonseed oil but also saturated, mono- and polyunsaturated fatty acids (PUFAs), such as arachidonic acid and fatty alcohols such as octyldodecanol, or also co-solvents such as hexane, xylene, etc.
  • Vegetable oils in particular such as those mentioned above, are preferred.
  • the formulation in the form of a core-shell capsule can be one which has a liquid core, in particular a liquid hydrophilic core, with a shell formed from hydrophobic oleogels. That is to say that the oleogel formulation according to the invention is suitable for forming the shell of such core-shell capsules.
  • These core-shell capsules according to the invention are particularly suitable for providing formulations with hydrophilic volatile components and / or active ingredients, these active ingredients optionally being dissolved in the hydrophilic liquid.
  • a layer can additionally be applied to the surface of the formulation obtained in this way based on the oleogel, which further inhibits diffusion or introduces other properties which change the surface of the formulation.
  • This can e.g. B. be done by adding wax or other additives.
  • the use of the formulation according to the invention as a crop protection agent or pest control agent is provided, which in particular comprises biocides, insecticides, fungicides, nematicides, acaricides or flerbicides containing such agents.
  • the hollow spheres can be removed from the oleogel sol and the oleogel shell formed with the filling contained therein can be completely solidified on an inert surface
  • the presence and the release rate of the volatiles formulated therein are examined by means of thermosorption-coupled gas chromatography and (thermo-) gravimetry.
  • the analysis of the formulations with volatile semiochemicals and without, as well as an unformulated semiochemical, clearly showed that the volatile semiochemical is released with a time delay at elevated temperatures. It was also found that the semiochemical is essentially completely present in the oleogel formulation. It was also possible to show what influence the addition of different wax concentrations in the ethyl cellulose oleogel formulation has on the release of the formulated volatile.

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pest Control & Pesticides (AREA)
  • Agronomy & Crop Science (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Plant Pathology (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

Dans un premier aspect, la présente invention concerne une formulation d'oléogel adaptée à la libération de composants volatiles, tels que des substances sémiochimiques ; cette formulation contient au moins un oléogélateur, tel que l'alkylcellulose, un composant volatile ainsi qu'un liquide non polaire. Dans un autre aspect, une formulation d'oléogel est mise au point, contenant un ingrédient actif comprenant au moins un gélateur, l'ingrédient actif ainsi qu'un liquide non polaire. La présente invention concerne en outre un procédé permettant la fabrication de la formulation d'oléogel selon l'invention. L'invention concerne enfin l'utilisation de la formulation d'oléogel selon l'invention en particulier comme produit phytosanitaire et pesticide mais également dans l'industrie alimentaire ou pharmaceutique, contenant des principes actifs pharmaceutiques ou cosmétiques, des arômes ou des parfums.
EP20746600.4A 2019-07-23 2020-07-23 Nouvelle formulation à base d'un oléogel, en particulier permettant la libération de composants volatiles, et procédé permettant la fabrication de celui-ci Pending EP4003010A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102019119888.7A DE102019119888A1 (de) 2019-07-23 2019-07-23 Neue Formulierung auf Basis eines Oleogels insbesondere zur Freisetzung von volatilen Komponenten und Verfahren zu dessen Herstellung
PCT/EP2020/070763 WO2021013917A1 (fr) 2019-07-23 2020-07-23 Nouvelle formulation à base d'un oléogel, en particulier permettant la libération de composants volatiles, et procédé permettant la fabrication de celui-ci

Publications (1)

Publication Number Publication Date
EP4003010A1 true EP4003010A1 (fr) 2022-06-01

Family

ID=71833316

Family Applications (1)

Application Number Title Priority Date Filing Date
EP20746600.4A Pending EP4003010A1 (fr) 2019-07-23 2020-07-23 Nouvelle formulation à base d'un oléogel, en particulier permettant la libération de composants volatiles, et procédé permettant la fabrication de celui-ci

Country Status (4)

Country Link
US (1) US20220256842A1 (fr)
EP (1) EP4003010A1 (fr)
DE (1) DE102019119888A1 (fr)
WO (1) WO2021013917A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4233541A1 (fr) 2022-02-28 2023-08-30 Fachhochschule Bielefeld Matériau support pour produits biologiques vivants et sa préparation

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3856699A (en) 1969-08-08 1974-12-24 Fuji Photo Film Co Ltd Process for producing capsules having walls of a waxy material
WO1990000005A1 (fr) 1988-06-30 1990-01-11 Redding Bruce K Jr Pesticides microencapsules a leurre
WO1999062497A1 (fr) * 1998-06-03 1999-12-09 Aiache Jean Marc Melange de gels stable constitue d'un oleogel et d'un gel aqueux
US6737394B2 (en) * 2002-03-04 2004-05-18 Unilever Home & Personal Care Usa, Division Of Conopco, Inc. Isotropic cleansing composition with benefit agent particles
US10744476B2 (en) 2007-05-31 2020-08-18 Philip Morris Usa Inc. Production of wax capsules containing liquid hydrophilic cores
DE102010033048A1 (de) 2010-08-02 2012-02-02 Katz Biotech Ag Verwendung eines mikroverkapselten Nahrungssubstrats
US9040034B2 (en) * 2013-04-09 2015-05-26 International Business Machines Corporation Vitamin functionalized gel-forming block copolymers for biomedical applications
US20160270400A1 (en) 2013-11-12 2016-09-22 Lipotec Laboratories Llc Liposome-Attractant Formulations
US10772841B2 (en) * 2014-04-07 2020-09-15 Patheon Softgels Inc. Opioid abuse-deterrent controlled release formulations
GB201419257D0 (en) * 2014-10-29 2014-12-10 Jagotec Ag Pharmaceutical compositions
DE102015016114A1 (de) 2015-12-11 2017-06-14 Katz Biotech Ag Flüssigkernkapseln zur Bekämpfung von Schädlingen
FR3053967B1 (fr) * 2016-07-12 2020-03-27 Centre National De La Recherche Scientifique (Cnrs) Organogels permettant de reduire et controler l'evaporation de liquides organiques volatils
US11666066B2 (en) * 2017-11-13 2023-06-06 Wm. Wrigley Jr. Company Organogel compositions and their use as a controlled delivery system in confectionery products

Also Published As

Publication number Publication date
WO2021013917A1 (fr) 2021-01-28
DE102019119888A1 (de) 2021-01-28
US20220256842A1 (en) 2022-08-18

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