EP3694645A1 - Dispositif comportant une première chambre pour la réception d'un fluide corporel - Google Patents

Dispositif comportant une première chambre pour la réception d'un fluide corporel

Info

Publication number
EP3694645A1
EP3694645A1 EP18793575.4A EP18793575A EP3694645A1 EP 3694645 A1 EP3694645 A1 EP 3694645A1 EP 18793575 A EP18793575 A EP 18793575A EP 3694645 A1 EP3694645 A1 EP 3694645A1
Authority
EP
European Patent Office
Prior art keywords
chamber
body fluid
guide
wall
centrifugation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP18793575.4A
Other languages
German (de)
English (en)
Other versions
EP3694645B1 (fr
Inventor
Nina Breidenbach
Julio Reinecke
Julien TROILLET
Peter Wehling
Julia HEINDIRK
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Orthogen AG
Original Assignee
Orthogen AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orthogen AG filed Critical Orthogen AG
Priority to PL18793575T priority Critical patent/PL3694645T3/pl
Publication of EP3694645A1 publication Critical patent/EP3694645A1/fr
Application granted granted Critical
Publication of EP3694645B1 publication Critical patent/EP3694645B1/fr
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/02Blood transfusion apparatus
    • A61M1/029Separating blood components present in distinct layers in a container, not otherwise provided for
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5021Test tubes specially adapted for centrifugation purposes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3693Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02Adapting objects or devices to another
    • B01L2200/026Fluid interfacing between devices or objects, e.g. connectors, inlet details
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06Fluid handling related problems
    • B01L2200/0621Control of the sequence of chambers filled or emptied
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/04Closures and closing means
    • B01L2300/041Connecting closures to device or container
    • B01L2300/044Connecting closures to device or container pierceable, e.g. films, membranes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/04Closures and closing means
    • B01L2300/041Connecting closures to device or container
    • B01L2300/045Connecting closures to device or container whereby the whole cover is slidable
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/06Auxiliary integrated devices, integrated components
    • B01L2300/0672Integrated piercing tool
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0832Geometry, shape and general structure cylindrical, tube shaped
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0861Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/087Multiple sequential chambers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0403Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0409Moving fluids with specific forces or mechanical means specific forces centrifugal forces
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0475Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0478Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure pistons

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Anesthesiology (AREA)
  • Pathology (AREA)
  • Cardiology (AREA)
  • External Artificial Organs (AREA)
  • Centrifugal Separators (AREA)
  • Air Bags (AREA)
  • Massaging Devices (AREA)

Abstract

L'invention concerne un dispositif de réception d'un fluide corporel, le dispositif comprenant : une première chambre munie d'une paroi coulissante et une deuxième chambre présentant une taille effective constante, qui peut être déplacée par rapport à la paroi mobile, le dispositif étant conçu de manière à relier la première chambre et la deuxième chambre en cas de mouvement axial longitudinal de la deuxième chambre par rapport à la paroi coulissante, et pour transférer du fluide corporel de la première chambre à la deuxième chambre en cas de mouvement conjoint de la deuxième chambre et de la paroi coulissante.
EP18793575.4A 2017-10-11 2018-10-10 Dispositif comportant une première et une deuxième chambre pour la réception d'un fluide corporel Active EP3694645B1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PL18793575T PL3694645T3 (pl) 2017-10-11 2018-10-10 Urządzenie z pierwszą i drugą komorą do przyjmowania płynu ustrojowego

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP17195982.8A EP3470142A1 (fr) 2017-10-11 2017-10-11 Dispositif doté d'une première chambre permettant de recevoir un liquide biologique
PCT/EP2018/077574 WO2019072903A1 (fr) 2017-10-11 2018-10-10 Dispositif comportant une première chambre pour la réception d'un fluide corporel

Publications (2)

Publication Number Publication Date
EP3694645A1 true EP3694645A1 (fr) 2020-08-19
EP3694645B1 EP3694645B1 (fr) 2021-12-01

Family

ID=60119852

Family Applications (2)

Application Number Title Priority Date Filing Date
EP17195982.8A Pending EP3470142A1 (fr) 2017-10-11 2017-10-11 Dispositif doté d'une première chambre permettant de recevoir un liquide biologique
EP18793575.4A Active EP3694645B1 (fr) 2017-10-11 2018-10-10 Dispositif comportant une première et une deuxième chambre pour la réception d'un fluide corporel

Family Applications Before (1)

Application Number Title Priority Date Filing Date
EP17195982.8A Pending EP3470142A1 (fr) 2017-10-11 2017-10-11 Dispositif doté d'une première chambre permettant de recevoir un liquide biologique

Country Status (13)

Country Link
US (1) US11896972B2 (fr)
EP (2) EP3470142A1 (fr)
JP (1) JP7303185B2 (fr)
KR (1) KR20200064093A (fr)
CN (1) CN111278563B (fr)
AU (1) AU2018348719B2 (fr)
BR (1) BR112020006199A2 (fr)
CA (1) CA3097515A1 (fr)
ES (1) ES2907935T3 (fr)
IL (1) IL273577A (fr)
MX (1) MX2020003432A (fr)
PL (1) PL3694645T3 (fr)
WO (1) WO2019072903A1 (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3830301A1 (fr) * 2018-08-01 2021-06-09 Mammoth Biosciences, Inc. Compositions de nucléase programmable et leurs méthodes d'utilisation
WO2020142754A2 (fr) 2019-01-04 2020-07-09 Mammoth Biosciences, Inc. Améliorations de nucléase programmable ainsi que compositions et méthodes d'amplification et de détection d'acide nucléique
DE102019206126A1 (de) * 2019-04-29 2020-10-29 B. Braun Melsungen Aktiengesellschaft Medizinische Fluidübertragungsvorrichtung
DE102019217908A1 (de) * 2019-11-20 2021-05-20 B. Braun Melsungen Aktiengesellschaft Medizinische Fluidübertragungsvorrichtung
KR102365747B1 (ko) * 2019-12-23 2022-02-22 (주)글로핀 원심분리기용 목표물질 추출키트 및 이를 이용한 목표물질 추출방법
AT523531B1 (de) * 2020-05-05 2021-09-15 Univ Wien Med Vorrichtung zum Verbinden einer Kanüle mit einem Behältnis
CN111974475B (zh) * 2020-08-20 2021-09-21 四川行之智汇知识产权运营有限公司 血液成分分离器

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LU39422A1 (fr) 1960-11-16
US3706305A (en) 1971-03-03 1972-12-19 Harold J Berger Combination blood sampling vacuum syringe centrifuge container and specimen cup
US4209488A (en) * 1978-10-10 1980-06-24 Owens-Illinois, Inc. Fluid collection apparatus
US4644807A (en) * 1985-02-21 1987-02-24 Dionex Corporation Fluid sample delivery apparatus
US4828716A (en) 1987-04-03 1989-05-09 Andronic Devices, Ltd. Apparatus and method for separating phases of blood
US5360011A (en) * 1993-07-13 1994-11-01 Mccallister Teresa D Blood sample collection
ZA948564B (en) 1993-11-19 1995-07-26 Bristol Myers Squibb Co Liquid separation apparatus and method
DE19903876B4 (de) 1999-02-01 2006-09-28 Orthogen Gentechnologie Gmbh Verfahren zur in-vitro-Bildung und Anreicherung von Interleukin-1 Rezeptor-Antagonisten
US6398972B1 (en) 1999-04-12 2002-06-04 Harvest Technologies Corporation Method for producing platelet rich plasma and/or platelet concentrate
US20030205538A1 (en) 2002-05-03 2003-11-06 Randel Dorian Methods and apparatus for isolating platelets from blood
ES2349749T3 (es) 2004-12-21 2011-01-11 BECTON, DICKINSON & COMPANY Conjunto de jeringuilla que tiene un mecanismo de inutilización.
US8052969B2 (en) * 2006-12-28 2011-11-08 Arthrex, Inc. Method of making plasma enriched with platelets using a double syringe system where the second sytringe is within the first syringe and use thereof
DE102007056759A1 (de) 2007-11-23 2009-05-28 Roderfeld, Enno, Dr. Blutentnahmevorrichtung
DE102008023545A1 (de) 2008-05-14 2009-11-19 Roderfeld Und Bora Gmbh & Co.Kg Vorrichtung zur Herstellung einer biologisch aktiven Substanz
EP2352533B1 (fr) 2008-12-01 2018-01-10 General Electric Company Système et procédé pour séparer des cellules nucleés de liquides biologiques
JP5691581B2 (ja) 2011-02-04 2015-04-01 ニプロ株式会社 多血小板血漿分離キット及び多血小板血漿分離方法
WO2012154257A1 (fr) 2011-02-17 2012-11-15 Prometheus Laboratories Inc. Appareil et procédé pour l'isolement de leucocytes et de cellules tumorales par filtration
BR112013022656B1 (pt) 2011-03-11 2021-06-22 Fenwal, Inc Sistema de coleta de sangue automático de passagem única
WO2014168409A1 (fr) 2013-04-11 2014-10-16 (주)굿모닝바이오 Récipient pour séparation du sang permettant d'extraire les plaquettes en vue d'une auto-transfusion

Also Published As

Publication number Publication date
EP3694645B1 (fr) 2021-12-01
CN111278563A (zh) 2020-06-12
JP7303185B2 (ja) 2023-07-04
EP3470142A1 (fr) 2019-04-17
KR20200064093A (ko) 2020-06-05
US11896972B2 (en) 2024-02-13
PL3694645T3 (pl) 2022-04-19
US20200238274A1 (en) 2020-07-30
AU2018348719A1 (en) 2020-04-16
CN111278563B (zh) 2022-12-20
RU2020114945A (ru) 2021-11-12
MX2020003432A (es) 2020-07-29
BR112020006199A2 (pt) 2020-10-13
AU2018348719B2 (en) 2023-07-27
CA3097515A1 (fr) 2019-04-18
ES2907935T3 (es) 2022-04-27
WO2019072903A1 (fr) 2019-04-18
IL273577A (en) 2020-05-31
JP2020536604A (ja) 2020-12-17

Similar Documents

Publication Publication Date Title
EP3694645B1 (fr) Dispositif comportant une première et une deuxième chambre pour la réception d'un fluide corporel
DE102010003223B4 (de) Vorrichtung zum Einsetzen in einen Rotor einer Zentrifuge, Zentrifuge und Verfahren zum fluidischen Koppeln von Kavitäten
DE69930192T2 (de) Vorrichtung und Verfahren zur Trennung von Bestandteilen einer flüssigen Probe
EP2292334B1 (fr) Centrifugeuse destinée à séparer du sang, récipients à communication fluidique correspondants, ainsi que procédé de production de concentré de thrombocytes hautement enrichis à partir de sang
DE69912785T2 (de) Vorrichtung zur filtration und extraktion und methode für ihre verwendung
EP3120929B1 (fr) Soupape d'admission pour systemes de chambres et recipients a echantillons ainsi que systemes de chambres dotes de recipients a echantillons dotes de telles soupapes d'admission
EP2413138B1 (fr) Dispositif et procédé de séparation de composants d'un liquide d'échantillon
EP1919625B1 (fr) Dispositif et procede de separation de particules magnetiques d'un liquide
DE2308485A1 (de) Vorrichtung zum trennen von fluessigen gemischen, insbesondere blut, in ihre bestandteile
DE2711731A1 (de) Fluid -sammelvorrichtung
WO2003019131A2 (fr) Procede et dispositif de preparation d'un prelevement d'origine biologique pour determiner au moins un constituants
DE10134913A1 (de) Vorrichtung und Verfahren zur Blutpräparation
EP0734767A2 (fr) Récepient pour le traitement à contamination réduite de liquides
EP2647433B1 (fr) Pièce d'insertion de flacon de réactif et flacon de réactif
EP3778027B1 (fr) Séparateur et procédé de séparation du plasma sanguin et des cellules sanguines
DE102015203779A1 (de) Vorrichtung zur automatisierten Prozessierung von Flüssigkeiten
WO2020234218A1 (fr) Système d'analyse microfluidique pour l'analyse d'échantillons de sang
EP3990179B1 (fr) Bouchon de fermeture pour fermer un tube pour prélèvement destiné à recevoir un liquide
DE102016123658B4 (de) Filtrationsvorrichtung und Verfahren zur Anreicherung von Targets und der nachfolgenden Freisetzung biogener Agenzien
EP2926906A1 (fr) Dispositif de soupape et dispositif de manipulation de liquides
DE2717963C2 (de) Einrichtung zur Aufbereitung von Probeflüssigkeiten, insbesondere zur Feststellung pathogener Mikroben in Körperflüssigkeiten
DE102011122579A1 (de) Verfahren zum Trennen von Suspensions- oder Kolloidbestandteilen und Vorrichtung zum Trennen von Suspensions- oder Kolloidbestandteilen
WO2023061630A1 (fr) Dispositif, en particulier cartouche microfluidique, et procédé, comprenant une chambre de prélèvement et un couvercle amovible
DE102019213313A1 (de) Zentrifugeneinheit für eine mikrofluidische Vorrichtung zur Prozessierung von flüssigen Proben
WO2007054159A1 (fr) Dispositif destine a l'obtention de suspensions cellulaires avec incorporation ulterieure d'additifs et procede associe

Legal Events

Date Code Title Description
STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: UNKNOWN

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE INTERNATIONAL PUBLICATION HAS BEEN MADE

PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: REQUEST FOR EXAMINATION WAS MADE

17P Request for examination filed

Effective date: 20200511

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

AX Request for extension of the european patent

Extension state: BA ME

DAV Request for validation of the european patent (deleted)
DAX Request for extension of the european patent (deleted)
GRAP Despatch of communication of intention to grant a patent

Free format text: ORIGINAL CODE: EPIDOSNIGR1

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: GRANT OF PATENT IS INTENDED

RIC1 Information provided on ipc code assigned before grant

Ipc: A61M 1/36 20060101ALI20210408BHEP

Ipc: A61M 1/02 20060101ALI20210408BHEP

Ipc: B01L 3/00 20060101AFI20210408BHEP

INTG Intention to grant announced

Effective date: 20210512

GRAS Grant fee paid

Free format text: ORIGINAL CODE: EPIDOSNIGR3

GRAA (expected) grant

Free format text: ORIGINAL CODE: 0009210

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE PATENT HAS BEEN GRANTED

AK Designated contracting states

Kind code of ref document: B1

Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

REG Reference to a national code

Ref country code: GB

Ref legal event code: FG4D

Free format text: NOT ENGLISH

REG Reference to a national code

Ref country code: AT

Ref legal event code: REF

Ref document number: 1451251

Country of ref document: AT

Kind code of ref document: T

Effective date: 20211215

Ref country code: CH

Ref legal event code: EP

REG Reference to a national code

Ref country code: IE

Ref legal event code: FG4D

Free format text: LANGUAGE OF EP DOCUMENT: GERMAN

REG Reference to a national code

Ref country code: DE

Ref legal event code: R096

Ref document number: 502018008065

Country of ref document: DE

REG Reference to a national code

Ref country code: CH

Ref legal event code: PK

Free format text: BERICHTIGUNGEN

REG Reference to a national code

Ref country code: NL

Ref legal event code: FP

REG Reference to a national code

Ref country code: LT

Ref legal event code: MG9D

REG Reference to a national code

Ref country code: ES

Ref legal event code: FG2A

Ref document number: 2907935

Country of ref document: ES

Kind code of ref document: T3

Effective date: 20220427

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: FI

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20211201

Ref country code: BG

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20220301

Ref country code: RS

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20211201

Ref country code: LT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20211201

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: SE

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20211201

Ref country code: NO

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20220301

Ref country code: LV

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20211201

Ref country code: HR

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20211201

Ref country code: GR

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20220302

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: SM

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20211201

Ref country code: SK

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20211201

Ref country code: RO

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20211201

Ref country code: PT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20220401

Ref country code: EE

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20211201

Ref country code: CZ

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20211201

REG Reference to a national code

Ref country code: DE

Ref legal event code: R097

Ref document number: 502018008065

Country of ref document: DE

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: IS

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20220401

PLBE No opposition filed within time limit

Free format text: ORIGINAL CODE: 0009261

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: NO OPPOSITION FILED WITHIN TIME LIMIT

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: DK

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20211201

Ref country code: AL

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20211201

26N No opposition filed

Effective date: 20220902

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: SI

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20211201

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: MC

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20211201

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: LU

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20221010

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: PL

Payment date: 20230928

Year of fee payment: 6

Ref country code: NL

Payment date: 20231023

Year of fee payment: 6

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: GB

Payment date: 20231025

Year of fee payment: 6

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: ES

Payment date: 20231117

Year of fee payment: 6

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: TR

Payment date: 20231003

Year of fee payment: 6

Ref country code: IT

Payment date: 20231031

Year of fee payment: 6

Ref country code: IE

Payment date: 20231019

Year of fee payment: 6

Ref country code: FR

Payment date: 20231023

Year of fee payment: 6

Ref country code: DE

Payment date: 20231120

Year of fee payment: 6

Ref country code: CH

Payment date: 20231102

Year of fee payment: 6

Ref country code: AT

Payment date: 20231019

Year of fee payment: 6

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: BE

Payment date: 20231023

Year of fee payment: 6

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: CY

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20211201