EP3661566A1 - Ensemble de décontamination, système ainsi que procédé de décontamination - Google Patents

Ensemble de décontamination, système ainsi que procédé de décontamination

Info

Publication number
EP3661566A1
EP3661566A1 EP18730990.1A EP18730990A EP3661566A1 EP 3661566 A1 EP3661566 A1 EP 3661566A1 EP 18730990 A EP18730990 A EP 18730990A EP 3661566 A1 EP3661566 A1 EP 3661566A1
Authority
EP
European Patent Office
Prior art keywords
decontamination
atomizers
pressure vessel
fluid
space
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP18730990.1A
Other languages
German (de)
English (en)
Inventor
Stefan Kleinmann
Thomas Kassner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Metall and Plastic GmbH
Original Assignee
Metall and Plastic GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Metall and Plastic GmbH filed Critical Metall and Plastic GmbH
Publication of EP3661566A1 publication Critical patent/EP3661566A1/fr
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/16—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
    • A61L2/22—Phase substances, e.g. smokes, aerosols or sprayed or atomised substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/16—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
    • A61L2/18—Liquid substances or solutions comprising solids or dissolved gases
    • A61L2/186—Peroxide solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2202/00—Aspects relating to methods or apparatus for disinfecting or sterilising materials or objects
    • A61L2202/10—Apparatus features
    • A61L2202/11—Apparatus for generating biocidal substances, e.g. vaporisers, UV lamps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2202/00—Aspects relating to methods or apparatus for disinfecting or sterilising materials or objects
    • A61L2202/10—Apparatus features
    • A61L2202/12—Apparatus for isolating biocidal substances from the environment
    • A61L2202/122—Chambers for sterilisation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2202/00—Aspects relating to methods or apparatus for disinfecting or sterilising materials or objects
    • A61L2202/10—Apparatus features
    • A61L2202/15—Biocide distribution means, e.g. nozzles, pumps, manifolds, fans, baffles, sprayers

Definitions

  • the invention relates to a decontamination arrangement, in particular for pharmaceutical applications, according to the preamble of claim 1, comprising at least one space to be decontaminated, in particular an isolator space, preferably a manipulator space and / or one of the manipulator space via a membrane (for laminarizing the air flow during operation after decontamination) separate plenum space, further comprising a decontamination liquid container from the plurality of arranged in the space to be decontaminated, preferably designed as two-fluid nozzles, atomizer for generating a
  • Dekontaminationsmittelaerosols with decontamination fluid preferably hydrogen peroxide, are supplied via at least one supply line.
  • the invention relates to a system according to claim 12, comprising an insulator, which is preferably adapted for pharmaceutical applications, with a space to be decontaminated, in particular a manipulator space and / or a separate from the manipulator chamber via a membrane for laminarizing an air flow of a circulating air blower of the insulator Plenum room and with a decontamination arrangement according to the invention.
  • the circulating air blower is preferably arranged in a recirculation generator space above the abovementioned plenum space.
  • the manipulator space is air-conductively connected to the recirculation generator space via a return flow channel which is more preferably formed between two transparent disks.
  • a dosing and / or a Filling device for a pharmaceutical agent and / or a manufacturing device for such an active ingredient arranged. It is particularly preferred if the manipulator space is accessible to an operator via gloves for manual intervention from the outside, wherein the gloves or so-called glove ports are arranged or fixed in a side wall of the manipulator space.
  • the invention relates to a decontamination method according to the preamble of claim 13, in particular for operating a decontamination arrangement according to the invention and / or a system according to the invention, wherein a space to be decontaminated, in particular an insulator space, preferably a manipulator space and / or a separate from the manipulator space via a membrane Plenum space is decontaminated by means arranged in the space to be decontaminated, preferably designed as compressed air supplied with two-fluid nozzles, a decontamination liquid aerosol from a
  • Decontamination liquid in particular hydrogen peroxide, is generated, which are supplied for this purpose with the decontamination liquid from the decontamination liquid container.
  • WO 201 1/085735 A1 or EP 2 719 962 A1 describes a decontamination arrangement comprising a pharmaceutical isolator and an H 2 O 2 evaporator.
  • the H 2 O 2 evaporator flash evaporator
  • the H 2 O 2 evaporator is connected via a supply line directly to a plenum space, which is separated from an underlying manipulator space via a membrane for generating a laminar air flow during operation of the insulator.
  • hydrogen peroxide vapor is introduced into the plenum via the supply line, wherein the Hydrogen peroxide vapor passes through the membrane down into the manipulator room.
  • WO 2013/003967 A1 describes a decontamination arrangement in which hydrogen peroxide is not vaporized conventionally via a flash evaporator, but in which two-substance nozzles are used in order to atomize the liquid hydrogen peroxide, ie to produce an aerosol.
  • a reservoir and an atomizer are an integral part of a device which can be installed as a whole in the space to be decontaminated.
  • solutions are known from practice, in which a plurality of atomizers are connected to a common decontamination liquid container via a respective end to the associated atomizer supply line.
  • Each supply line are assigned a pump and a valve.
  • the individual supply lines are filled via the respective pump; only then does the actual decontamination cycle begin, in which decontamination fluid is indicated via the atomizers in the space to be decontaminated in the form of an aerosol.
  • the supply lines are again emptied into the decontamination liquid container in order to determine the amount of decontamination liquid delivered via the atomizer total, including the Feed pumps are operated backwards.
  • the total amount of spent or discharged decontamination fluid is determined by subtraction of the container weight before filling the supply lines and the weight of the container after completion of the decontamination cycle and after the emptying of the supply lines.
  • Decontamination process is the elaborate determination of the total amount of decontamination fluid dispensed necessary for a validated decontamination process, since all supply lines must be emptied back into the container for this purpose.
  • the control of the plurality of pumps is complex and faulty or toleranced.
  • EP 2 889 045 A1 describes a pharmaceutical isolator in which an atomizer is operated intermittently and a further finest distribution is achieved by intermittent operation of a blower. The atomizer sucks in hydrogen peroxide from a pressureless decontamination fluid tank, which in turn is filled via a pump from a decontamination fluid tank. This principle is also described in EP 2 692 848 B1. Due to the suction pressure prevailing by the suction of the hydrogen peroxide in the supply line there is a risk of gas bubble formation over the entire conveying path.
  • the present invention seeks to provide an improved decontamination arrangement, in particular for pharmaceutical applications and an improved decontamination process, which provides reproducible decontamination results and also has a simple structure.
  • the inventive Decontamination assembly and the decontamination method according to the invention make it possible to easily and accurately determine the total amount of decontamination fluid delivered via the atomizers during a decontamination cycle.
  • Decontamination fluid container is formed as connected to a compressed air source pressure vessel in which by pressurizing, in particular sterile compressed air from the compressed air source, a delivery pressure can be generated by the decontamination of the pressure tank through the at least one supply line in the direction of the atomizer, preferably up to the atomizers is eligible.
  • the compressed air source comprises a compressed air compressor and / or a compressed air tank and / or a compressed air cylinder. It is particularly preferred if the compressed air source in the flow direction of the air before the pressure vessel a filter, in particular according to pharmaceutical standards (preferably 0.22mm) is arranged downstream, or alternatively upstream to ensure the supply of the pressure vessel with sterile compressed air.
  • the object is achieved with the features of claim 12 and with respect to the decontamination process with the features of claim 13, ie in a generic method, characterized in that the decontamination liquid container is formed as connected to a compressed air source pressure vessel in which by applying, in particular sterile, compressed air from the compressed air source, a delivery pressure is generated, with which the decontamination fluid from the pressure vessel in the direction of the atomizer, preferably conveyed to the atomizers.
  • Advantageous developments of the invention are specified in the subclaims. All combinations of at least two of the features disclosed in the description, claims and / or figures fall within the scope of the invention.
  • the invention is based on the idea to provide as a decontamination liquid container a pressure vessel in which with, in particular sterile, compressed air from a compressed air source, a delivery pressure is generated or can be generated, with which decontamination fluid from the pressure vessel distributed to the atomizer or in the direction of the atomizer through the at least one supply line, in particular the plurality, in particular a common distribution section dividing supply lines can be conveyed.
  • active, ie electrical feed pumps are dispensed with in a region between the decontamination liquid container designed as a pressure container and the atomizers for conveying the decontamination liquid from the decontamination liquid container to the atomizers. This simplifies the design and control of the device or of active components considerably.
  • the total amount of decontamination fluid discharged via the atomizers during a decontamination cycle can be easily determined without decontamination fluid from the at least one to have to feed a supply line back into the decontamination fluid tank.
  • Another significant advantage of the invention is that due to the delivery pressure generated by compressed air critical negative pressures in the at least one supply line, at least over most of its longitudinal extension can be avoided, leading to gas bubble formation and thus possibly an uneven distribution of the decontamination on the Nebulizer or a shortage of individual atomizers can lead to decontamination fluid.
  • Such an embodiment with throttling means is particularly useful when a comparatively low delivery pressure is to be selected and / or in the flow direction of the decontamination fluid before the atomizers not one, in particular clocked operable switching valve is arranged.
  • the invention provides a simple by the compressed air delivery of decontamination fluid in the direction of the atomizer System structure and a good basis for a large number of possible training courses as well as for a validatable, repeatable and reliable decontamination process.
  • the decontamination arrangement it is possible and provided within the scope of the invention for the decontamination arrangement to have a plurality of spaces to be decontaminated. It is possible to assign individual rooms each a pressure tank with this associated atomizers.
  • An alternative embodiment can also be implemented, in which the pressure tank supplies atomizers arranged in different rooms via at least one corresponding supply line.
  • the delivery pressure is selected from a value range between 0.2 bar and 0.8 bar, even more preferably between 0.25 bar and 0.5 bar.
  • the abovementioned pressure ranges are preferred ranges, which in practice may, however, also deviate from this, in particular it may be preferable to select or set a higher delivery pressure in the case of the provision of switching valves.
  • the delivery pressure depends on the type or type of atomizer used, in particular the design of the nozzle. Some atomizers require a higher inlet or discharge pressure than others.
  • the delivery pressure is dependent on whether the atomizers a valve, in particular a switching valve is arranged upstream and if so, the optimal delivery pressure in turn depends on the type of valve or the valve type. Basically, valves with a smaller flow cross section or diameter require a higher delivery pressure.
  • a Dekontaminations remplikeitsvorrats constituer is connected, from which the pressure vessel with decontamination fluid over, in particular one, even more preferably electrically operated, conveying pump comprehensive, funding is supplied.
  • the conveying means are controlled such that the fluid flow is influenced, for example via a valve, so that the pressure vessel is filled with a predetermined amount of decontamination fluid, which can be adjusted in particular by the user, within the scope of a decontamination cycle, either at once or in several filling steps. It can the
  • Dekontaminations hookkeitsmenge be determined, for example, characterized in that the reservoir is arranged on a balance and the amount delivered to the pressure vessel is classically detected by subtraction. Additionally or alternatively, the use of a flow meter (flow meter) is possible. It is also conceivable to arrange in the pressure vessel a level gauge, in particular a pressure switch, which emits a corresponding signal for stopping the conveying means and / or closing a valve upon reaching a predetermined filling quantity.
  • the pressure vessel in the invention Druckeinstellstoff for holding the delivery pressure in the pressure vessel in a predetermined, in particular adjustable range associated with the pressure range is preferably selected between 0.2bar and 0.8bar, in particular between 0.25bar and 0.8bar.
  • the maximum difference of the supply line lengths is preferably 20%, preferably 10%, even more preferably only 5%, wherein it is very particularly preferred if the line lengths to the atomizers are the same.
  • a compressed air pressure below the vapor pressure of the decontamination liquid in the case of hydrogen peroxide 5 mm Hg, at 30.degree. C.
  • a compressed air pressure below the vapor pressure of the decontamination liquid can generally result from the pressurization of the atomizers in the respective supply line.
  • Either the delivery pressure should be selected so high that the vapor pressure of the decontamination fluid, at least over the largest portion or part of the length of the at least one supply line is not exceeded or in the case of realization of low delivery pressures, it is advantageous in a range in the flow direction of Decontamination fluid before the Atomizers in the at least one supply line corresponding throttle means to provide a diaphragm in the simplest case, which is responsible for a correspondingly sufficient overpressure between the throttle means and the pressure tank, in particular over a majority of the longitudinal extent of the at least one supply line concern.
  • the throttle means may not be adjustable in the simplest case, for example, be designed as a diaphragm or throttle valve.
  • Conceivable is alternatively also the realization of adjustable throttle means, for example in the form of a proportional valve for varying the throttle effect and thus the fluid pressure in a region between the throttle means and the pressure tank.
  • adjustable throttle means for example in the form of a proportional valve for varying the throttle effect and thus the fluid pressure in a region between the throttle means and the pressure tank.
  • the throttle means are located immediately in front of the respective atomizer.
  • valve means in the form of switching valves in the flow direction of the decontamination liquid are arranged in front of the atomizers, which can be operated more preferably clocked to deliver pulsed or pulsed aerosol to the room to be decontaminated.
  • additional throttle means then preferably in the flow direction of the decontamination fluid upstream of the switching valves, realized.
  • each valve means in the form of, in particular clocked controllable, switching valves, most preferably 2- / 2-way valves provided are over which the atomizer can be supplied with decontamination fluid from the pressure vessel.
  • this is Understand feature of the supply of the atomizer via valve means so that the decontamination liquid must pass through or flow on their flow path from the pressure vessel to the atomizers corresponding valve means.
  • the valve means can be controlled via control means (control device), in particular open and closed.
  • the valve means are formed so that with these a fluid-conducting connection between the atomizers and the pressure vessel, in particular clocked, can be interrupted.
  • the discretely switching switching valves in particular in the form of the aforementioned 2- / 2-way valves are preferably arranged such that between each atomizers, in particular all atomizers and the pressure vessel each such valve is and / or between the pressure vessel and at least one group of atomizers , In the case of providing a plurality of atomizer groups arranged on the pressure vessel, it is preferable to associate such a valve with each group. For optimum control and influenceability of the decontamination fluid aerosol generation, however, it is preferable to assign each atomizer its own valve, in particular a switching valve, ie a valve that can be switched between a fully closed and a fully open valve position.
  • the distance of the switching valves to the respectively associated atomizer is as short as possible.
  • the atomizer With regard to the specific design of the atomizer, there are again different possibilities. Thus, it is conceivable in principle to use ultrasonic atomizers or atomizers working on other physical principles of action. However, it is very particularly preferred to use two-substance nozzles (mixing nozzles) as atomizers, which are connected to a compressed-air source for producing a stream of carrier gas. Alternatively, it is also possible to use single-substance nozzles, in particular for smaller spaces to be decontaminated, which are preferably also operated pulsed or supplied with decontamination fluid. In principle, it is advantageous if the atomizers are in any case designed in such a way that 90% of the decontamination mist or aerosol droplets leaving the atomizers have a particle size of less than 20 ⁇ , preferably less than 10 ⁇ .
  • the atomizers detection means in particular a respective flow switch are assigned to be able to check whether actually decontamination liquid is present and / or discharged into the space to be decontaminated via the respective atomizer.
  • the invention also leads to a decontamination process, which is disclosed in large part in the foregoing description of the device. According to the invention, it is provided
  • the decontamination liquid is conveyed by means of or due to the delivery pressure at least up to the conveying means, whereby possibly the minimized distance between the throttling means and the atomizers by or possibly only takes place with the assistance of suction pressure, which can occur in the case of the use of two-fluid nozzles as an atomizer or occurs.
  • the at least one supply line is preferably blown over the atomizers by means of the compressed air or the delivery pressure into the space to be decontaminated.
  • the corresponding valves of the decontamination arrangement can be controlled or controlled by a controller in such a way that a defined amount of decontamination liquid from the
  • Decontamination fluid reservoir is promoted at one time or in several steps in the empty or emptied pressure vessel or conveyed and this entire amount is promoted by appropriate Druck Kunststoffbeetzschung the pressure vessel in the direction of the atomizers or is conveyed and discharged through this in the space to be decontaminated is or can be dispensed, wherein the total amount (filling) of decontamination fluid, which is conveyed during a Dekontaminationszyklus in the pressure vessel, for example by weighing by means of a balance (difference) can be determined and / or other means for delivering a defined amount of decontamination, for example a Pressure switch, which stops on reaching a predetermined Grelevels of the pressure vessel, the funding and / or closes a valve or the like.
  • FIG. 1 shows in the single FIGURE 1 a fluid scheme for preferred embodiments of a trained according to the concept of the invention decontamination arrangement in which the space to be decontaminated an insulator space in the present case is preferably a manipulator space.
  • FIG. 1 shows in the single FIGURE 1 a fluid scheme for preferred embodiments of a trained according to the concept of the invention decontamination arrangement in which the space to be decontaminated an insulator space in the present case is preferably a manipulator space.
  • FIG. 1 shows an isolator system 1 with an insulator 2 for pharmaceutical applications and a decontamination arrangement 3 associated with the isolator 2 for decontaminating a decontaminating space 4, which in the present case is a so-called manipulator space of the insulator 2 in that a pharmaceutical-technical process, for example a dosing or production and / or filling process, takes place with the appropriate machinery or apparatus, it being possible to intervene manually in the manipulator space via glove ports (not shown).
  • a pharmaceutical-technical process for example a dosing or production and / or filling process
  • the manipulator space is connected in a conventional manner via at least one return flow channel with a arranged above the space to be decontaminated Um Kunststoffer Wegerraum in which there is a circulating air blower over which a circulating air volume flow can be generated during operation of the insulator 2 and that of the circulating air space via corresponding Hoch insschwebstofffilter in a so-called plenum space into and over this through a membrane into the manipulator space.
  • the aforementioned return flow channels are preferably formed in sections between two transparent panes, in particular transparent glass panes.
  • the decontamination arrangement comprises a plurality of atomizers A, B, C, which are each designed as two-substance nozzles (mixing nozzle).
  • each atomizer A, B, C connected to an associated compressed air supply line 5, 6, 7, which in turn can be supplied with compressed air from a compressed air source 8, which in turn are assigned or downstream of filter media according to pharmaceutical standard for producing sterile air.
  • the compressed air supply lines 5, 6, 7 are associated with pressure measuring means 10 in order to check the applied pressure can.
  • These pressure measuring means 10 are preceded by pressure reducing means 1 1 to reduce the supply pressure of the compressed air source 8 of preferably at least 6bar.
  • pressure reducing means 1 1 to reduce the supply pressure of the compressed air source 8 of preferably at least 6bar.
  • the compressed air supply of the atomizers A, B, C can be opened or closed.
  • the respectively applied pressure of the carrier gas stream can be adjusted via adjusting means which are integrated in the pressure supply line 5, 6, 7, in particular manually operable.
  • With FS the downstream of the setting means 13, 14, 15 flow switches (flow switches) with an upper and a lower limit to check whether the carrier gas pressure at the atomizers A, B, C is in a
  • the compressed air source 8 serves at the same time for acting as a pressure vessel 16 formed Dekontaminations remplikeits macers.
  • different sources of compressed air for supplying the two-fluid nozzles and the pressure vessel 16 may be provided.
  • the pressure vessel 16 is preceded by a pressure reduction valve 18 in the associated compressed air supply line 17, wherein the delivery pressure generated by the pressurization in the pressure vessel via a pressure control valve 19 (holding means) is maintained in a predetermined range of values.
  • a discharge valve 20 in particular for filling the pressure vessel 16 with decontamination liquid, residual pressure can be released to the atmosphere.
  • the prevailing pressure in the pressure vessel 16 pressure is monitored by appropriate pressure measuring means 21.
  • a Dekontaminations remplikeitsvorrats constituer 22 is connected at the pressure vessel 16.
  • the pressure vessel 16 via conveying means 23, in this case an electrically driven pump, with a predetermined, settable Dekontaminations remplikeitsmenge filled (after the pressure vessel 16 was previously completely emptied).
  • the amount delivered in the pressure vessel 16 for a decontamination cycle is determined here by way of example by weighing - for this purpose the decontamination liquid reservoir 22 is mounted on a balance 24.
  • decontamination liquid here hydrogen peroxide conveyed over the applied, in particular for subsequent filling with decontamination fluid delivery pressure via supply lines 25, 26, 27 which are dimensioned such that the atomizer A, B, C are the same distance from the pressure vessel 16 relative to the respective supply line length.
  • the decontamination liquid transport from the pressure vessel 16 to the atomizers A, B, C can be started and interrupted via a valve 28.
  • the pressure tank is still assigned a level gauge 29.

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)

Abstract

La présente invention concerne un ensemble de décontamination, en particulier pour des applications pharmaceutiques, comprenant au moins une salle à décontaminer (4), en particulier une salle propre, de préférence une salle de manipulation et/ou une salle sous vide séparée de la salle de manipulation par une membrane, et comprenant en outre un réservoir (22) de liquide de décontamination à partir duquel plusieurs brumisateurs (A, B, C) agencés dans la salle à décontaminer (4), de préférence conçus comme des buses binaires, pour produire un aérosol de décontamination avec un liquide de décontamination, de préférence du peroxyde d'hydrogène, peuvent être alimentés à l'aide d'au moins une conduite d'alimentation (25, 26, 27), le réservoir (22) de liquide de décontamination étant conçu comme un réservoir sous pression (16) raccordé à une source d'air comprimé (8), dans lequel il est possible de produire, en appliquant notamment de l'air comprimé stérile provenant de la source d'air comprimé (8), une pression de refoulement au moyen de laquelle le liquide de décontamination peut être acheminé depuis le réservoir sous pression (16) en direction des brumisateurs (A, B, C) à l'aide de la ou des conduites d'alimentation (25, 26, 27).
EP18730990.1A 2017-08-02 2018-05-30 Ensemble de décontamination, système ainsi que procédé de décontamination Pending EP3661566A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102017117568.7A DE102017117568A1 (de) 2017-08-02 2017-08-02 Dekontaminationsanordnung, System sowie Dekontaminationsverfahren
PCT/EP2018/064160 WO2019025052A1 (fr) 2017-08-02 2018-05-30 Ensemble de décontamination, système ainsi que procédé de décontamination

Publications (1)

Publication Number Publication Date
EP3661566A1 true EP3661566A1 (fr) 2020-06-10

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Country Link
EP (1) EP3661566A1 (fr)
DE (1) DE102017117568A1 (fr)
WO (1) WO2019025052A1 (fr)

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CN114459089A (zh) * 2022-02-11 2022-05-10 杭州卓尔净化工程有限公司 一种用于称量室的无菌自净风循环装置
CN115006570B (zh) * 2022-06-28 2024-05-17 科立恩(苏州)医疗器械有限公司 一种可调流量的移动式过氧化氢消毒机

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EP2535650B1 (fr) 2010-01-13 2016-12-14 Metall + Plastic GmbH Agencement de décontamination ainsi que procédé
WO2012132146A1 (fr) 2011-03-29 2012-10-04 パナソニック ヘルスケア株式会社 Dispositif de pulvérisation de solution de décontamination
CH705249A1 (de) 2011-07-04 2013-01-15 Skan Ag Vorrichtung zur Dekontamination für ein Containment und/oder von temporär darin einbringbarem Behandlungsgut.
DE102013000064A1 (de) * 2013-01-08 2014-07-10 Lothar Saiger Verfahren zur Reinigung und / oder Desinfektion von medizinischen/zahnmedizinischen Instrumenten und zahnärztlichen Abdrücken. Wesentliche Bauteile die bei der Anwendung dieses Verfahrens eingesetzt werden können: Verteilerblock zur Verteilung der Medien und Grundkörper mit Düsen. Verfahren zur Herstellung von Düsen und/oder deren Zuleitung
EP2889045B1 (fr) 2013-03-29 2017-09-27 Panasonic Healthcare Holdings Co., Ltd. Système d'isolation
EP3244934B1 (fr) * 2016-04-07 2018-05-09 Metall + Plastic GmbH Système de décontamination

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