EP3369409B1 - Dispositif et procédé de dosage de matériaux de remplissage pulvérulents - Google Patents

Dispositif et procédé de dosage de matériaux de remplissage pulvérulents Download PDF

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Publication number
EP3369409B1
EP3369409B1 EP17000326.3A EP17000326A EP3369409B1 EP 3369409 B1 EP3369409 B1 EP 3369409B1 EP 17000326 A EP17000326 A EP 17000326A EP 3369409 B1 EP3369409 B1 EP 3369409B1
Authority
EP
European Patent Office
Prior art keywords
dosing
filling material
rotational movement
plunger
powder
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
EP17000326.3A
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German (de)
English (en)
Other versions
EP3369409A1 (fr
Inventor
Marco Weigel
Florian Huhnen
Jonas Höpfer
Philipp GAUS
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Harro Hofliger Verpackungsmaschinen GmbH
Original Assignee
Harro Hofliger Verpackungsmaschinen GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Harro Hofliger Verpackungsmaschinen GmbH filed Critical Harro Hofliger Verpackungsmaschinen GmbH
Priority to EP17000326.3A priority Critical patent/EP3369409B1/fr
Publication of EP3369409A1 publication Critical patent/EP3369409A1/fr
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Publication of EP3369409B1 publication Critical patent/EP3369409B1/fr
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
    • A61J3/071—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use into the form of telescopically engaged two-piece capsules
    • A61J3/074—Filling capsules; Related operations
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B1/00—Packaging fluent solid material, e.g. powders, granular or loose fibrous material, loose masses of small articles, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans, or jars
    • B65B1/30—Devices or methods for controlling or determining the quantity or quality or the material fed or filled
    • B65B1/36—Devices or methods for controlling or determining the quantity or quality or the material fed or filled by volumetric devices or methods
    • B65B1/38—Devices or methods for controlling or determining the quantity or quality or the material fed or filled by volumetric devices or methods by pistons co-operating with measuring chambers

Definitions

  • the invention relates to a device and a method by means of which a powdery filling material can be dosed.
  • the powdery contents can then be transferred, in particular into hard gelatine capsules, but also into other containers.
  • Devices and methods of this type are used in particular in the pharmaceutical industry for filling hard gelatine capsules with drugs.
  • the powder to be filled is filled into a dosing chamber, for example into the bores of a dosing disk.
  • the powder is then compacted in the dosing chamber using a stamp.
  • the ram performs at least one lifting movement, so that a compact is formed.
  • the finished compact is then pressed out of the dosing chamber by opening the dosing chamber and ejecting the compact by means of a stamp.
  • a stamp For example, in DE 10 2015 206407 A1 shown.
  • the invention is based on the object of specifying an improved device for dosing powdered filling material, by means of which dosing inaccuracies can be avoided.
  • the device according to the invention for dosing powdery filling material has a filling material container in which the powdery filling material can be kept in stock.
  • a defined quantity of the powdery filling material can be removed from this filling material container by means of a metering tool and transferred to a container, for example to the lower part of a hard gelatine capsule.
  • the dosing tool is designed to be movable in its longitudinal direction.
  • the dosing tool can be set into a rotational movement about its longitudinal axis by a drive unit.
  • a defined rotational movement is carried out by this drive unit, which prevents the powdered solid from adhering to the dosing tool. Dosing inaccuracies can thus be avoided, which leads to fewer rejects and thus to increased productivity.
  • a first motor drive by means of which the metering tool can be moved along its longitudinal axis.
  • the dosing tool is rotated by means of a separately designed drive unit.
  • the rotational movement can affect this Way done independently of the transport movement of the metering tool by means of the first motor drive.
  • several dosing tools could be moved in the longitudinal direction by means of a common motor drive.
  • the drive unit can enable both a clockwise rotational movement and a counter-clockwise rotational movement.
  • an alternating clockwise and anti-clockwise rotation can generate a pendulum or shearing movement, which can particularly effectively prevent solids from adhering to the metering tool.
  • the dosing tool is designed as a stamp.
  • at least one dosing chamber is formed at the base of the filling material container, into which a defined quantity of the filling material can be filled.
  • the filling material in the dosing chamber can first be compacted by the stamp to form a compact. The compact can then be ejected from the dosing chamber by the plunger.
  • the rotary movements of the ram can be carried out during the compaction of the powdery filling material in the dosing chamber and/or during the ejection of the compact from the dosing chamber.
  • Rotational movements during the compaction of the powdered filling material in the dosing chamber can already prevent the compact from adhering to the stamp.
  • a rotational movement during the ejection of the compact from the dosing chamber can ensure that the compact can be detached more easily from the plunger.
  • a rotational movement can be applied during only one of the two processes, or a combination. It would also be possible to have the punch continuously perform a rotational movement.
  • the dosing tool can be designed as a siphon.
  • the pipette can be immersed in the powder bed present in the filling material container in order to remove a defined quantity of filling material. Then the amount of powder present in the dosing chamber of the pipette can be transferred to a container that is available.
  • the rotational movements of the siphon can be carried out during the immersion of the siphon into the powder bed and/or during the ejection of the powder from the dosing chamber of the siphon.
  • Rotational movements during the immersion of the pipette into the powder bed can already prevent powder from adhering to the inner walls of the dosing chamber of the pipette at an early stage and thus enable the dosing chamber to be filled completely and precisely.
  • a rotational movement during the ejection of the powder from the dosing chamber of the siphon can ensure a complete and easy ejection of the powder.
  • a rotary movement can only be applied during one of the two processes, or a combination. It would also be possible to have the siphon continuously perform a rotational movement.
  • At least one rotational movement of the dosing piston should take place during a rotational movement of the siphon.
  • This rotational movement can already be sufficient to effectively prevent powder from sticking in the dosing chamber.
  • the dosing sleeve could also perform a rotational movement.
  • the rotational movements of the dosing piston and dosing sleeve can run in opposite directions to one another, so that a shearing movement takes place.
  • the device 10 is in Figures 1 and 2 shown.
  • the device 10 has a stamp 20 as a dosing tool, which can be set in a vertical lifting movement (arrow 22) by means of a motor drive, not shown here.
  • the plunger 20 moves through the stroke movement 22 in the bore 24 of a metering disk 26.
  • Each bore 24 of the metering disk 26 forms a metering chamber.
  • the bore 24 is closed by a plate 28 from the underside.
  • the bore 24 can initially be filled with a defined quantity of filling material.
  • the punch 20 can then in accordance with the powder present in the bore 24 1 compact to a pellet 30.
  • the plunger 20 in the embodiment shown here is set into a rotational movement (arrow 34) by a drive unit 32 .
  • the rotation 34 of the plunger 20 during the compacting of the filling material can ensure that the compact 30 being produced does not stick to the underside of the plunger 20 .
  • the rotational movement 34 takes place at a constant speed in the clockwise direction.
  • the rotational movement 34 could also take place in a counter-clockwise direction.
  • the speed during the rotational movement 34 could be varied.
  • the rotational movement could consist of several smaller, jerky movements.
  • the direction of rotation could also be changed at predetermined intervals, so that it would rotate first clockwise and then counter-clockwise. This change in direction could then be repeated as often as desired.
  • this is the lower part 40 of a hard gelatine capsule.
  • the lower capsule part 40 is positioned below the dosing chamber 24 by means of a receiving unit 42 .
  • the lower capsule part 40 can be removed laterally by the receiving unit 42 so that a new lower capsule part can be positioned under the dosing chamber 24 .
  • the filled lower capsule part 40 can then be provided with another pellet or another product in further processing stations, or it can also be closed directly.
  • the supply and removal of Capsule bottoms can be done in particular by a rotary indexing table, as for example from the EP 1 415 637 A1 or the EP 2 135 810 A1 is known.
  • the ram 20 is caused to rotate (arrow 44) by the drive unit 32 while the compact 30 is being ejected.
  • the rotation 44 of the stamp 20 during the ejection of the compact 30 detaches the compact 30 more easily from the underside of the stamp 20 and can fall into the lower capsule part 40 safely and reliably.
  • the rotational movement 44 can take place in a manner comparable to the rotational movement 34 with a constant rotational speed and direction, but also with a varying rotational speed and/or rotational direction. It would be possible to use both the rotational movement 34 during compacting ( 1 ) as well as the rotational motion 44 during ejection ( 2 ) to perform. In this case, the two rotational movements 34, 44 can be identical, but they can also be executed differently, adapted to the different situations. However, depending on the filling material used, the cycle speed of the rotary indexing table and/or the size of the compact 30, it may be sufficient to provide only the rotary movement 34 during the compaction of the filling material or the rotary movement 44 during the ejection of the compact 30 from the dosing chamber 24.
  • a device 12 not belonging to the invention is in Figures 3 and 4 shown.
  • the device 12 has a plunger 50 as a dosing tool, which can be set in a vertical lifting motion (arrow 52) by means of a motor drive, not shown here. Due to the lifting movement 52, the pipette 50 moves downwards into the filling material 56 present in a filling material container 54 and upwards out of it again.
  • the siphon 50 has an outer dosing sleeve 60 and a dosing piston 62 movably guided therein.
  • the dosing piston 62 is retracted a little from the free edge 64 of the dosing sleeve 60, so that a dosing chamber 66 is formed within the dosing sleeve 60.
  • the dosing sleeve 60 is in 3 is immersed with its free edge 64 in the filling material 56 that is present in the filling material container 54 and forms a powder bed. When the siphon 50 is immersed, the dosing chamber 66 is filled with the filling material 56.
  • the dosing piston 62 of the siphon 50 in the embodiment shown here is set in rotation by a drive unit 70 (arrow 72).
  • This rotation 72 of the dosing piston can ensure that the filling material 56 is distributed evenly in the dosing chamber 66, so that an optimal and reproducible filling of the dosing chamber 66 is achieved.
  • the rotational movement 72 takes place at a constant speed in the clockwise direction.
  • the rotational movement 72 could also take place in a counter-clockwise direction.
  • the speed during the rotational movement 72 could be varied.
  • the rotational movement could consist of several smaller, jerky movements.
  • the direction of rotation could also be changed at predetermined intervals, so that it would rotate first in a clockwise direction and then in a counter-clockwise direction. This change in direction could then be repeated as often as desired.
  • the amount of powder predetermined by the volume of the dosing chamber 66 remains in the dosing chamber 66 when the pipette 50 is pulled out of the powder bed. In this way, the powder can be transported with the siphon 50 and filled out of the dosing chamber 66 into a container provided for this purpose by means of the dosing piston 62 (see Fig 4 ). In the present example, this is the lower part 40 of a hard gelatine capsule was positioned below the lancing siphon 50 by means of a receiving unit 42 . In the present example, the dosing piston 62 of the siphon 50 is caused to rotate (arrow 74) by the drive unit 70 during the ejection of the powder present in the dosing chamber 66 . Due to the rotation 74 of the dosing piston 62 during the ejection of the powder, the dosing chamber 66 can be emptied quickly and completely.
  • the rotational movement 74 can take place in a manner comparable to the rotational movement 72 with a constant rotational speed and direction, but also with a varying rotational speed and/or rotational direction. In this case, it would be possible both the rotational movement 72 during the immersion of the pipette 50 into the filling material 56 ( 3 ) as well as the rotational movement 74 during the ejection of the powder ( 2 ) to perform. In this case, the two rotational movements 72, 74 can be identical, but they can also be executed differently, adapted to the different situations. However, it can also be sufficient to merely provide the rotational movement 72 during the immersion of the pipette 50 into the filling material 56 or the rotational movement 74 during the ejection of the powder from the dosing chamber 66 .

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Basic Packing Technique (AREA)

Claims (4)

  1. Dispositif (10, 12) pour le dosage de produit en vrac pulvérulent (56),
    - avec un contenant de produit en vrac (54),
    - avec un disque de dosage (26) qui est agencé au fond du contenant de produit en vrac (54), au moins une chambre de dosage (24) étant présente dans le disque de dosage (26),
    - avec une plaque (28) par laquelle la chambre de dosage (24) peut être fermée à partir du côté inférieur du disque de dosage (24),
    - avec au moins un poinçon (20) mobile dans sa direction longitudinale, au moyen duquel une quantité définie du produit en vrac pulvérulent (56) peut être transférée dans un récipient (40),
    - avec un premier entraînement motorisé, au moyen duquel le poinçon (20) peut être déplacé dans un mouvement de soulèvement (22) le long de son axe longitudinal,
    - caractérisé en ce que
    - au moins une unité d'entraînement (32) est présente, par laquelle l'au moins un poinçon (20) peut être mis dans un mouvement de rotation (34, 44) autour de son axe longitudinal,
    - l'unité d'entraînement (32) pour la rotation (34, 44) du poinçon (20) est configurée sous forme d'entraînement séparé, de telle sorte que le mouvement de rotation (34, 44) peut s'effectuer indépendamment du mouvement de soulèvement (22).
  2. Dispositif selon la revendication 1,
    - caractérisé en ce que
    - l'au moins un poinçon (20) peut être mis par l'unité d'entraînement (32) dans un mouvement de rotation (34, 44) dans le sens des aiguilles d'une montre et/ou dans un mouvement de rotation dans le sens inverse des aiguilles d'une montre.
  3. Dispositif selon la revendication 2,
    - caractérisé en ce que
    - l'au moins un poinçon (20) peut être mis par l'unité d'entraînement (32) dans un mouvement pendulaire autour de son axe longitudinal.
  4. Dispositif selon l'une quelconque des revendications précédentes,
    - caractérisé en ce que
    - le poinçon (20) permet de compacter une quantité définie du produit en vrac pulvérulent à l'intérieur de la chambre de dosage (24) en un comprimé (30),
    - le comprimé (30) peut être expulsé de la chambre de dosage (24) par le poinçon (20).
EP17000326.3A 2017-03-02 2017-03-02 Dispositif et procédé de dosage de matériaux de remplissage pulvérulents Active EP3369409B1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP17000326.3A EP3369409B1 (fr) 2017-03-02 2017-03-02 Dispositif et procédé de dosage de matériaux de remplissage pulvérulents

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP17000326.3A EP3369409B1 (fr) 2017-03-02 2017-03-02 Dispositif et procédé de dosage de matériaux de remplissage pulvérulents

Publications (2)

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EP3369409A1 EP3369409A1 (fr) 2018-09-05
EP3369409B1 true EP3369409B1 (fr) 2023-07-12

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Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT201900012504A1 (it) * 2019-07-22 2021-01-22 Ima Spa Macchina e metodo per riempire capsule.

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102015206407A1 (de) * 2015-04-10 2016-10-13 Robert Bosch Gmbh Vorrichtung zum Dosieren von pulverförmigem Füllgut

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2050885C3 (de) * 1969-10-21 1974-02-28 Fratelli Zanasi S.P.A., Ozzano Emilia, Bologna (Italien) Verfahren zur Dosierung von pulverformigen Stoffen mit Hilfe eines Stechheberdosiergeräts
IT1304780B1 (it) * 1998-12-03 2001-03-29 Ima Spa Apparato per rilevare funzioni relative alla massa di tutte le dosi diprodotto da confezionare in capsule di gelatina dura, per rilevare
DE20216953U1 (de) 2002-10-31 2002-12-19 Hoefliger Harro Verpackung Rundschalttisch zum Befüllen von Behältnissen mit Pulver
DE102007031856A1 (de) 2007-07-09 2009-01-15 Robert Bosch Gmbh Vorrichtung zum Dosieren von pulverförmigem Füllgut
DE202008007921U1 (de) 2008-06-16 2008-08-21 Harro Höfliger Verpackungsmaschinen GmbH Taktweise antreibbarer Rundschalttisch zum Befüllen von Behältnissen mit Pulver

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102015206407A1 (de) * 2015-04-10 2016-10-13 Robert Bosch Gmbh Vorrichtung zum Dosieren von pulverförmigem Füllgut

Also Published As

Publication number Publication date
EP3369409A1 (fr) 2018-09-05

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