EP3137027A1 - Dispositif pour pratiquer des incisions ou des perforations dans l'oeil - Google Patents

Dispositif pour pratiquer des incisions ou des perforations dans l'oeil

Info

Publication number
EP3137027A1
EP3137027A1 EP15727462.2A EP15727462A EP3137027A1 EP 3137027 A1 EP3137027 A1 EP 3137027A1 EP 15727462 A EP15727462 A EP 15727462A EP 3137027 A1 EP3137027 A1 EP 3137027A1
Authority
EP
European Patent Office
Prior art keywords
eye
cutting element
cutting
field generator
field
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP15727462.2A
Other languages
German (de)
English (en)
Inventor
Georg Gerten
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Vossamed & Co KG GmbH
Original Assignee
Vossamed & Co KG GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vossamed & Co KG GmbH filed Critical Vossamed & Co KG GmbH
Publication of EP3137027A1 publication Critical patent/EP3137027A1/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007—Methods or devices for eye surgery
    • A61F9/00736—Instruments for removal of intra-ocular material or intra-ocular injection, e.g. cataract instruments
    • A61F9/00754—Instruments for removal of intra-ocular material or intra-ocular injection, e.g. cataract instruments for cutting or perforating the anterior lens capsule, e.g. capsulotomes

Definitions

  • the invention relates to a device for generating from cuts or perforations in the human or animal eye front or rear opening of the eye lens (capsulotomy, Rhexis), with an insertable inside the eye cutting element and one outside the eye arranged drive means to the cutting element inside the eye in a movement, in particular in oscillating oscillations or rotation too offset.
  • the device according to the invention is particularly suitable for use in ophthalmic surgery, especially for cutting out parts of Capsule of the human eye lens.
  • IOL intraocular lens
  • Rhexis the intraocular lens
  • the Rhexis is decisive for the outcome of the entire operation.
  • Your Stability / integrity is important to the course of the operation itself.
  • the aim is a round Rhexis without edges, tears or inhomogeneities, because such forms a stable hole in the capsular bag. This tears the Capsular bag during the operation despite the manipulation inside the lens not a.
  • the rear capsule leaf can are overgrown by epithelial cells, clouding and visually disturbing.
  • IOL intraocular artificial lens
  • Nd: YAG laser a Nd: YAG laser
  • Rhexis a Rhexis too large in relation to the IOL (pinching the IOL optics in the Rhexis and decentration of the IOL).
  • Rhexis which does not circularly cover the front of the IOL optics, may cause pressure the shrinking Rhexiskante on the IOL optics and decentrations of the IOL to lead. The same applies to a non-circular shape of the Rhexis.
  • Rhexis In addition to the previously described Rhexis, the most one be as circular centered hole in the front of the capsular bag should (other, more oval forms of rhexis can in certain situations also be useful), in some cases, a rear Rhexis is generated. This is also a circular hole in the back of the lens capsule. In principle, similar considerations apply to the rear rhexis as to the front rhexis. However, a rear rhexis is technically even more difficult too generate and also medically risky. The anterior vitreous body abuts the posterior capsule directly to and the anterior vitreous border membrane should not be injured by a rear rhexis.
  • Previous method for opening the capsule the Eye lenses are based on mechanical methods or optical methods, ie Laser surgical procedures, in particular using a Femtosecond laser.
  • the simplest mechanical procedures become complete executed manually.
  • a needle or tweezers in the front Eye chamber introduced. This will then perforate the front capsule and enter more or less round, central hole of about 5mm diameter in the front Capsule ruptured (Rhexis or capsulotomy).
  • Centering, shape, size and Stability / integrity of a capsulorhexis generated in this way hang strong of the skill of the surgeon and the conditions in each Isolated case.
  • the manual procedures can also be supported with devices be, e.g. with the Fugo Blade® or Cystotome®.
  • the optical cutting / perforation of the lens capsule using ultrashort pulsed laser systems is already in clinical use.
  • the tissue interactions of ultrashort pulsed lasers are exploited.
  • the perforation is done by non-linear effects over the Ionization / plasma formation in the eye tissue at extremely high photon densities.
  • the resulting expansion of the cavitation bubble eventually ruptures the local Tissue.
  • the perforation of the posterior capsule is postoperative as Secondary treatment usually with Nd: YAG lasers, the infrared laser pulses in the nano- or picosecond range with mJ of energy.
  • Femtosecond lasers for capsulotomy during surgery. These lasers usually emit radiation in the near-infrared or ultra-violet range. there pulses are emitted from a few fs to a few 100 fs. This succeeds more precise cutting of eye tissue with significantly less energy input (Single pulses in the ⁇ J range).
  • the achievable capsulotomies are clinical very stable, centered and circular.
  • the patient's eye has to be firmly connected with such a laser device. The patient must be under The laser device can be spent and the patient's eye sucked. Operating time and procedure are extended by this. The devices are also quite large, considerably maintenance-intensive and expensive.
  • Clinical Investigations of the significant value of a centered, rounded and integrity Rhexis can be confirmed as they are generated with a femtosecond laser can.
  • the capsule has considerable elasticity (Modulus of elasticity approx. 1.3 N / mm2). This must be during mechanical perforation / cutting of the Capsule to be considered. These are u.a. Cutting heads have been described, which suck in the capsule during the cutting process. (WO 2009/140414 A1) These have several disadvantages.
  • the aspiration of the lens capsule within the eye is not without risk, as the reservoir of liquid in the front Eye chamber is limited, it can cause the collapse of the anterior chamber and eye tissue can be damaged. This is especially because of that probably because the aspirator in the eye with corresponding negative pressure work and therefore must be quite large and immobile.
  • US 5 269 787 discloses one on a shaft arranged cutting ring for making an opening in the front capsule of the human eye, where the shaft is attached to an ultrasound source is connected to vibrate the cutting ring and thereby perforating the anterior capsule.
  • the object of the invention is to provide a device for Perforating and / or cutting tissue especially on the eye, which in a simple way a position and shape-appropriate, clean cut can be carried out.
  • the drive device has a field generator for generating a having magnetic or electro-magnetic generator field and the Cutting element excitable by means of the field generated by the field generator and thus can be driven without mechanical coupling.
  • the drive of the Cutting elements, over a magnetic field, that of coils of the outside of the Auges arranged field generator is generated.
  • the cutting element contains itself ferromagnetic parts and is therefore with the help of (electro-) magnetic field excitable. It can thereby become inside the eye in one Rotation, a partial rotation or one in a circumferential direction of the then preferably as a cutting ring formed cutting element or a before and be returned oscillating oscillation.
  • a particularly advantageous has a Embodiment proved in which the cutting element movable, in particular rotatably mounted on a holding element and with this by an opening in the Eye is inserted into the inside of the eye.
  • the cutting element which at the distal, free end of the Holding element is mounted, insert into the eye and in the desired Hold cutting position while the (rotary) driving the cutting element then contactless by switching on the magnetic generated by the field generator Fields done.
  • the retaining element for this purpose by means of a dedicated robot to be manipulated, the tool with Handle high accuracy and reliable in the found position keep calm.
  • the invention requires no direct mechanical connection for transmitting power from a drive source (e.g. an electric motor or the like.) On the cutting element.
  • a drive source e.g. an electric motor or the like.
  • the invention uses the transmission of force through a magnetic field and thus generates fast, mechanical vibrations / rotations of the cutting element to the desired Cut or perform the perforation, for example, to the Open the lens capsule of one eye.
  • the oscillation or rotational frequency is preferably in a range of more than 30 Hz, more preferably more than 50 Hz and even more preferably in the kHz or even in the ultrasonic range.
  • the Frequency can be of an order of magnitude that is either significant is lower or higher than the elastic relaxation time (natural frequency) of Membrane or the eye lens capsule, which is particularly reliable Cutting effect or a perforation is achieved, even if the cutting edge of the moving cutting element is not optimally sharp is ground and / or in the case of a running as a cutting ring Cutting elements on the lens capsule is not circular.
  • Et al these Property makes it possible for the cutting element of metals or with out ferromagnetic excitable metal at least partially coated plastic to manufacture as a disposable device.
  • the vibrations caused by the cutting element of the magnetic field acting on it can be oscillating.
  • the cutting element can be set in a rotational movement And it is of course also possible, an oscillation of the cutting element with a rotation to improve the cutting effect.
  • the Frequency of the rotational movement may differ from that of the vibration.
  • the Field generator preferably has at least two traveling field generator forming excitation magnets, for example, comprise electromagnets or can consist of such. It is also not required that Cutting element to perform the desired cut a full or even executes several revolutions, but it is sufficient with appropriate Design of the cutting element, for example as a cutting ring with a over the entire circumference circumferential cutting edge, a partial rotation by one if necessary, even only a small angle of rotation of a few degrees to the lens capsule open.
  • the Exciter magnets may be arranged on an annular magnet carrier, which in the Insert the head of a patient at a distance.
  • the field generator or its Locating magnets can be positioned on the eye or near the eyes by holding for example, a near or on the dermis (sclera) and / or the Cornea (cornea) of the eye positionable, preferably annular or ring-segment-shaped contact element, wherein the exciter magnets on the Contact element are arranged.
  • the cutting element consists at least partially made of a ferromagnetic material, in particular of metal, or it is with a ferromagnetic coating or a ferromagnetic Core provided.
  • the cutting element not guided by a mechanical holding element during the cutting process may be a holding and positioning magnetic field for the cutting element generating magnet means may be provided to the cutting element in the of Surgeon desired position.
  • This magnetic device may e.g. in the Essentially of at least one permanent magnet and / or a switchable Electromagnets are formed.
  • a suction of the lens capsule or to cutting tissue is basically not necessary.
  • the cutting element can be considered in particular be designed closed cutting ring, so that it is a circumferential Cutting edge forms or similar to a pot saw with serrated cutting side is designed. But it is also possible, the cutting element in the manner of a to perform two- or multi-bladed rotor whose rotor blades at their radially outer ends are provided with sharp cutting edges. Particularly preferred in this embodiment is a two-bladed rotor.
  • the rotor blades may then preferably be designed so that they pass through Introduced a small cut or bore in the eye along its length can be, so their sharp cutting edges towards the too show opening eye lens.
  • the cutting element may be a central shaft or Have hub with which it rotates on the holding element and at least back and forth can be movably mounted. It performs in the electromagnetic field fast, mostly circular motion, leaving in the capsule a round hole arises.
  • the rotor blades therefore not stab- or needle-shaped, but perpendicular to the direction of the magnetic field lines generated by the field generator, a have comparatively large area, which is effective in the magnetic field.
  • This design is particularly advantageous when the cutting element only the stray field of the magnetic field is applied. Due to the comparatively large area of the rotor blades extends the field strength of the Magnetic stray field then still reliable to the rotor over his the rotor blades sent, for example, arranged radially outside to bring ferromagnetic areas into motion.
  • the cutting element is made of elastic Made of materials or material combinations. This makes it possible to Press together cutting element or fold or otherwise deform, making it by the usual in eye surgery very small Incisions can be introduced into the eye, for example, by passing through a fine tube is injected into the inside of the eye.
  • the for the cutting head or the cutting element used materials may e.g. also Have shape-memory properties. Fast altering / expanding materials (e.g., nitinol as in WO 2012/082386 A1 described) are less suitable because jerky movements in the Eye anterior chamber uncontrolled contact and possibly injury intraocular tissue. They are mostly metals or Plastic-metal combinations are suitable, which are slow after compression deform back to its original shape.
  • energy input mechanical, electrical, optical
  • the Memory effect particularly easy to achieve, since the cutting element after a shape change, e.g. Compression in an injector, only once at his Must remember form.
  • Alternatively or supportive others may mechanical elements, such as micro-springs or elastic bridges, a Change the shape of the cutting element in the eye effect.
  • Optical elements can be attached to the cutting head be in order to allow a centering of the capsule-cutting device in the eye, possibly in combination with a laser beam or light marks, surgical microscope, computer controlled video system.
  • the cutting element with a central aperture, a lens or an optical gap provided be arranged with a preferably arranged on the field generator optical Centering such as a crosshair, a laser aiming beam or Light beam for position determination and / or positioning of the cutting element can be acted upon.
  • the invention thus provides a novel device for Perforation / cutting of tissues, especially in or on the eye.
  • the device is used for anterior and posterior perforation (capsulotomy, Rhexis) of the human eye lens.
  • the device has a cutting element or Also cutting head on, the or through a small incision into the eye is insertable, and has an out of the eye facility, with the cutting element on electro-magnetic way mechanical vibrations or movements are generated as a small electric motor.
  • the opening of the eyelid capsule has a diameter in the Range of several tens of ⁇ m to several millimeters (e.g., 0.01 to 10 mm).
  • the construction can be done using a Cutting elements with ring-shaped closed (straight) cutting edge such be that the cutting ring significantly in z-axis, i. towards the Lens capsule and back vibrates, i. the field generator then works together with the cutting element in the manner of an (oscillating) linear motor. Vibrations in a perpendicular x / y plane may vary Construction of the cutting element have a lower cut quality.
  • the preferably oscillating oscillation of the cutting head can be supported by a rotational movement.
  • the electromagnetic field generated by the field generator may cause a rotational movement of the cutting element or parts thereof.
  • the rotational movement and the oscillation in circumference can - or Z-direction have different frequencies.
  • the frequency of the vibrations is in any case like that chosen that a clean perforation of the lens capsule is achieved, which in the As a rule, this is guaranteed if the frequency is either significantly lower or greater than the natural frequency of the tissue to be cut. Ideally It is in the range of a few Hz over the KHz range up to the MHz range (Ultrasonic). The vibration of the cutting element or one on this arranged cutting edge is required only for a short time ( ⁇ 1 min) to the to perform the desired cut.
  • the cutting element can by the at a Eye surgery usual incisions (cuts under about 2.8mm) in the eye be introduced. This is done by the usual injector or tube systems through which intraocular artificial lenses, Capsule tension rings, vitreous instruments and the like in eye surgery in the Inside of the eye are introduced.
  • the materials are in the injector system compressed and unfold in the eye or take in the eye again their original shape.
  • materials with memory properties suitable In the case of the cutting head this can be (metal coated) Plastics and metals with shape-memory properties be.
  • the memory effect can be e.g. optical, temperature dependent or be triggered mechanically.
  • the cutting head or the cutting element can be so be designed that an optical element its centering, and thus the Rhexis, relative to the optical axes (face line, apex of the cornea, middle the entrance pupil, Purkinje reflexes) of the eye.
  • This can be the Cutting head or the cutting element, for example, a central Have opening / lens / optical gap in the middle.
  • This can then be of one optical element (e.g., laser aiming beam, light on the surgical microscope) become.
  • the eye of the surgeon himself can be used for centering or the centering can be controlled via electronic image processing become.
  • FIG. 1 shows a schematic representation of a first Embodiment of the device according to the invention for carrying out a Rhexis on the human eye in section;
  • FIG. 2 shows the subject of FIG. 1 in a plan view on the eye
  • FIG. 3 shows a second embodiment of the invention in simplified representation in a head view of one with the device treated patients
  • FIG. 5 shows the subject of FIG. 4 in a Side view.
  • Figures 1 and 2 show a first embodiment a device according to the invention, for generating a Rhexis, so a circular section in the eye 10 for opening the eye lens 11 is used.
  • the device has a cutting element 12, which has a small Incision 13 in the cornea 14 of the eye 10 to be operated on the inside of the eye can be introduced.
  • the cutting element can be elastically deformable for this purpose be it by the comparatively small section 13 with the eye surgeon known methods comparable to an intraocular lens in the interior of the eye introduce.
  • the cutting element is magnetizable or magnetic, what it either completely made of a metal with ferromagnetic properties or a metallic coating, a ferromagnetic core or a strut of (ferromagnetic) metal has.
  • the device further includes an outside of the Auges arranged drive device 15, the essential part of a Field generator 16 for generating an electromagnetic generator field, the indicated schematically by the dotted lines 17 in the drawings is.
  • the electromagnetic generator field generated by the field generator 16 acts on the inserted into the inner eye cutting element 12 by this moves back and forth in the axial direction in Z-axis 18 and / or rotatory about the Z-axis drives or oscillating in a torsional vibration added.
  • the field generator 16 more in a ring segment-shaped Contact element 19 arranged excitation magnets 20, which are at Electromagnets, which is used to generate the generator field by means of a only schematically shown control unit 21 connected become.
  • the excitation magnets 20 are driven in such a way that they open on generate a circular path wandering generator field around the Z-axis 18, due the cutting element 12 inside the eye in a corresponding rotation is offset.
  • the circular rotating generator field a generator field be superimposed in the Z axis by a preferably pulsating arrival and Shutdown of the exciter magnets, bringing to the cutting element a force in Axial direction is exerted against the eye lens 11, against which the annular Cutting element 12 with its front cutting edge 22 presses.
  • ring segment-shaped Contact element 19 on which in the embodiment, a total of six Exciting magnets are arranged, one over an angle of about 120 ° extending interruption 23 has.
  • a Work area for the surgeon free by attaching the incision 13 can, inserted through the cutting element inside the eye and after Generating the cut can be removed again and through which the Cutting element with a suitable tool before switching on the field generator can be aligned correctly.
  • the incision 13 is then used later, to introduce the artificial lens to be implanted into the eye.
  • the device is one with the field generator 16th arranged centering means, wherein it is at the first Embodiment to two light beam projectors, not shown acts, with which on the cornea of the eye a crosshairs are projected can, which is designated 24 in Fig. 2.
  • the cutting element 12 has a optical centering, for example, also one of two itself crossing, preferably flexible struts or threads existing cross whose Crossing point from the surgeon just below the crossing point of the crosshair 14 is brought so as to the cutting element 12 exactly in the desired position to bring the eye lens 11. It is possible, this in Fig. 1 at 25 to provide indicated centering element of a ferromagnetic material, so that this centering element for the implementation of the electromagnetic field provides the desired mechanical movement of the cutting element 12.
  • the second embodiment differs from the embodiment of FIGS. 1 and 2 substantially in that the field generator for the generation of the electromagnetic field not in the immediate vicinity of the cutting element right on the eye of the is arranged on an operating apparatus, but on an apparatus that the surrounds the entire head of the patient at a greater distance from the cutting element.
  • the Excitation magnets are arranged on magnetic carriers 26, of which several preferably at even angular distance from each other the head of the patient Surrounded at the level of the eye to be operated on. It can be seen that in the in Fig. 3 illustrated embodiment of the operating table 27 with the lying on it Patients can be moved laterally to optimally the eye to be operated on to adjust relative to the magnetic carriers 26.
  • a cutting element used in the invention can.
  • the cutting element 12 in this embodiment has two approximately cloverleaf-shaped rotor blades 28 attached to a central shaft 29 of the as two-bladed rotor 30 configured cutting element are mounted.
  • the Rotor shaft 29 is rotatably mounted on a holding element 31, with which the Cutting element from the surgeon through the incision in the eye into the inside of the eye introduced and held there in the desired position.
  • the Rotor blades of relatively large areas of soft magnetic Material are formed, this can be elastically deformable, so they fold up for insertion of the element into the inner eye and make it smaller.
  • a contactless, magnetic, quasi electromotive drive for moving the cutting element created within the eye, wherein the cutting element to the movable rotor and the field generator corresponds to the stationary stator. It is with the invention possible to use the eye lens with high precision for performing a capsulotomy open, wherein during the actual cutting process external influences, such as they in previously known systems due to a mechanical coupling of the Cutting elements on the associated drive regularly occurred, reliable be avoided.
  • Memory material can be plastic materials or metallic materials, the original form, for example, when exposed to light or Recover heat energy

Landscapes

  • Health & Medical Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Vascular Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Prostheses (AREA)

Abstract

L'invention concerne un dispositif pour pratiquer des incisions ou des perforations dans un œil humain ou animal pour ouvrir le cristallin (11) (capsulotomie, rhéxis). Le dispositif fonctionne avec un élément coupant (12) pouvant être introduit à l'intérieur de l'œil et un dispositif d'entraînement (15) disposé à l'extérieur de l'œil (10), permettant de faire tourner ou notamment osciller mécaniquement l'élément coupant à l'intérieur de l'œil. L'invention vise à éviter les impacts extérieurs indésirables et à garantir ainsi une exécution très précise de l'incision en dotant le système d'entraînement d'un générateur de champ (16) permettant de produire un champ magnétique ou électromagnétique (17) et en rendant l'élément coupant excitable, en particulier entraînable au moyen du champ produit par le générateur de champ. Il se produit ainsi un actionnement magnétique de l'élément coupant à l'intérieur de l'œil sans que l'énergie cinétique alors dégagée ne doive être transférée mécaniquement de l'extérieur vers l'intérieur sur l'élément coupant au cours de l'opération d'incision.
EP15727462.2A 2014-04-28 2015-04-27 Dispositif pour pratiquer des incisions ou des perforations dans l'oeil Withdrawn EP3137027A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102014105943.3A DE102014105943A1 (de) 2014-04-28 2014-04-28 Vorrichtung zum Erzeugen von Schnitten oder Perforationen am Auge
PCT/IB2015/053047 WO2015166394A1 (fr) 2014-04-28 2015-04-27 Dispositif pour pratiquer des incisions ou des perforations dans l'œil

Publications (1)

Publication Number Publication Date
EP3137027A1 true EP3137027A1 (fr) 2017-03-08

Family

ID=53298561

Family Applications (1)

Application Number Title Priority Date Filing Date
EP15727462.2A Withdrawn EP3137027A1 (fr) 2014-04-28 2015-04-27 Dispositif pour pratiquer des incisions ou des perforations dans l'oeil

Country Status (5)

Country Link
US (1) US10213338B2 (fr)
EP (1) EP3137027A1 (fr)
CN (1) CN106232067B (fr)
DE (1) DE102014105943A1 (fr)
WO (1) WO2015166394A1 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014193702A1 (fr) 2013-05-31 2014-12-04 The Regents Of The University Of Colorado, A Body Corporate Dispositifs et procédés pour créer un capsulorhexis prévisible de diamètre spécifique
WO2018217579A1 (fr) * 2017-05-20 2018-11-29 Iantech, Inc. Procédés et systèmes de chirurgie ophthalmique
IT201800010363A1 (it) 2018-11-15 2020-05-15 Enrico Marchini Dispositivo e metodo della capsulotomia
DE102021109773A1 (de) * 2021-04-19 2022-10-20 Carl Zeiss Ag Phakoemulsifikationssystem

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0170650B1 (fr) * 1984-01-30 1988-05-04 SCHLEGEL, Hans-Joachim Appareil pour perforer la paroi frontale de la capsule du cristallin de l'oeil d'un etre vivant
DE4012882A1 (de) * 1990-04-23 1991-10-31 Michael Dr Med Sasu Ophthalmologisches skalpell fuer katarakt-operationen
US5269787A (en) 1991-12-17 1993-12-14 Cozean Jr Charles H Apparatus and method for capsulorhexis
WO1998048746A1 (fr) * 1997-04-25 1998-11-05 Technolas Gmbh Ophthalmologische Systeme Ablation laser ophtalmique a double mode
JP2002526148A (ja) * 1998-10-02 2002-08-20 ステリオタクシス インコーポレイテツド 身体の腔および洞から物質を取り除くための磁気的にナビゲート可能なおよび／または制御可能な装置
IL134370A0 (en) 2000-02-03 2001-04-30 Cutmed Ltd A medical instrument for use in cataract surgery and a method for use thereof
US7101379B2 (en) * 2001-04-02 2006-09-05 Acmi Corporation Retrieval basket for a surgical device and system and method for manufacturing same
DE10220253A1 (de) * 2001-05-04 2002-11-14 Michael Ulrich Dardenne Chirurgisches Instrument zum Ausführen runder Schnitte, zum Ausputzen eines linsenförmigen biologischen Objektes und zum Zerstören eines biologischen Objektes
US7166118B2 (en) * 2002-11-27 2007-01-23 Bausch & Lomb Incorporated Microkeratome blade assembly
US8702698B2 (en) 2008-05-15 2014-04-22 Mynosys Cellular Devices, Inc. Ophthalmic surgical device for capsulotomy
US8075578B2 (en) 2009-03-23 2011-12-13 V.R. Hexis Ltd. Apparatus and method for making a circular incision
US20100312252A1 (en) 2009-06-03 2010-12-09 Guangyao Jia Capsularhexis device with flexible heating element having an angled transitional neck
US20120158027A1 (en) 2010-12-16 2012-06-21 Ala Moradian Capsulotomy methods and apparatus using heat
US8591577B2 (en) * 2010-12-16 2013-11-26 Bausch & Lomb Incorporated Capsulotomy device and method using electromagnetic induction heating
US20130066351A1 (en) * 2011-03-08 2013-03-14 Christopher Kenneth Giardina Apparatus for creating an annular incision in soft tissue

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See references of WO2015166394A1 *

Also Published As

Publication number Publication date
WO2015166394A1 (fr) 2015-11-05
CN106232067A (zh) 2016-12-14
CN106232067B (zh) 2018-10-23
DE102014105943A1 (de) 2015-10-29
US10213338B2 (en) 2019-02-26
US20170042734A1 (en) 2017-02-16

Similar Documents

Publication Publication Date Title
EP2292194B1 (fr) Adaptateur destiné au couplage mécanique d'un dispositif d'usinage au laser et d'un objet
EP1810645B1 (fr) Dispositif et procédé destinés à l'exécution d'opérations ophtalmologiques
EP1126805B1 (fr) Instrument medical pour phaco-emulsification
WO2015166394A1 (fr) Dispositif pour pratiquer des incisions ou des perforations dans l'œil
DE102007044790A1 (de) Einhandgerät für die Augenchirurgie
DE102004021754A1 (de) Vorrichtung zum Entfernen von Epithelzellen aus einem Linsenkapselsack eines menschlichen oder tierischen Auges
WO2001037767A1 (fr) Dispositif pour ameliorer l'evacuation de l'humeur aqueuse de l'oeil d'un etre vivant
DE102011109058A1 (de) "Ophthalmologische Laservorrichtung und Verfahren zur Prävention und zur Behandlung von Nachstar"
EP0623328A1 (fr) Appareil chirurgical pour pulvériser et enlever le noyau du cristallin d'un oeil d'un être vivant
DE102010022298A1 (de) Vorrichtung und Verfahren zur Kataraktchirurgie
DE112008002511T5 (de) Verfahren und Vorrichtungen für integrierte Kataraktchirurgie
EP2908788A1 (fr) Dispositif et procédé d'exposition de l' oeil à un rayonnement
DE102013106920A1 (de) Gerätesystem und Verfahren zur Phakoemulsifikation
WO2019170752A1 (fr) Implant de dérivation
DE102013218415A1 (de) Augenchirurgisches Verfahren
DE2309205A1 (de) Chirurgische vorrichtung
EP2872083A1 (fr) Capsulotomie postérieure à l'aide de techniques laser
DE102017207529A1 (de) Nachbehandlung bei augenchirurgischer Refraktionskorrektur
DE102011116368A1 (de) Vorrichtung und Verfahren zur extrakapsulären chirurgischen Kataraktbehandlung
DE3736360C2 (de) Einrichtung zur klinischen Durchführung der außerkörperlichen Lithotripsie
DE60018517T2 (de) Mikrokeratom zur durchführung von hornhautresektionen
EP1441678B1 (fr) Dispositif de coupe
EP1087709B1 (fr) Instrument chirurgical pour emettre en continu ou par intermittence une lumiere laser et des ultrasons
DE102009053208A1 (de) Vorrichtung zur Überwachung der Implantation einer IOL (Orientierungsüberwachung)
DE102013223152A1 (de) System und Verfahren zur Erzeugung von Unterstützungsinformationen für lasergestützte Katarakt-Operation

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: REQUEST FOR EXAMINATION WAS MADE

17P Request for examination filed

Effective date: 20161128

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

AX Request for extension of the european patent

Extension state: BA ME

DAV Request for validation of the european patent (deleted)
DAX Request for extension of the european patent (deleted)
STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20201103