EP3090720A1 - Bouteille de collecte de plasma sanguin - Google Patents

Bouteille de collecte de plasma sanguin Download PDF

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Publication number
EP3090720A1
EP3090720A1 EP16168073.1A EP16168073A EP3090720A1 EP 3090720 A1 EP3090720 A1 EP 3090720A1 EP 16168073 A EP16168073 A EP 16168073A EP 3090720 A1 EP3090720 A1 EP 3090720A1
Authority
EP
European Patent Office
Prior art keywords
blood plasma
bottle
lid
plasma collection
bottle neck
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP16168073.1A
Other languages
German (de)
English (en)
Inventor
Reinhard Rettinghaus
Hubert Franzaring
Uwe Taborski
Jürgen Schulz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Octapharma Plasma GmbH
Original Assignee
Octapharma Plasma GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Octapharma Plasma GmbH filed Critical Octapharma Plasma GmbH
Publication of EP3090720A1 publication Critical patent/EP3090720A1/fr
Withdrawn legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14Details; Accessories therefor
    • A61J1/1412Containers with closing means, e.g. caps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14Details; Accessories therefor
    • A61J1/1443Containers with means for dispensing liquid medicaments in a filtered or sterile way, e.g. with bacterial filters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14Details; Accessories therefor
    • A61J1/1443Containers with means for dispensing liquid medicaments in a filtered or sterile way, e.g. with bacterial filters
    • A61J1/1456Containers with means for dispensing liquid medicaments in a filtered or sterile way, e.g. with bacterial filters using liquid filters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14Details; Accessories therefor
    • A61J1/1475Inlet or outlet ports
    • A61J1/1487Inlet or outlet ports with friction fit, e.g. connecting tubes directly to a protruding port
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14Details; Accessories therefor
    • A61J1/20Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2068Venting means

Definitions

  • the present invention relates to a plastic blood plasma collection bottle for storing blood plasma in the frozen state with a bottle body having a bottleneck at its top, wherein at the top of the bottle body on opposite sides of the bottle neck and laterally spaced therefrom are provided with connecting pieces, wherein a connection point for filling the bottle body with blood plasma and the sampling is used and at the connection piece of this connection point an L-shaped connector is provided, one connector leg is connected to the connecting piece and the other connector leg is directed to the bottle neck and a hose, and wherein the other connection point is the ventilation or venting of the bottle body.
  • Blood plasma collection containers have been known in the form of plastic bags for many years and have proven themselves through the use of materials such as ethylene-vinyl acetate (EVA) and polyethylene (PE) during freezing.
  • EVA ethylene-vinyl acetate
  • PE polyethylene
  • the disadvantage of blood plasma collection containers in the form of blood bags is the poor handling, as they can not be set up without tools or special designs and also there is a risk that they will be damaged in the frozen state when dropped. In addition, they bulge out unchecked, so that the amount is difficult to control.
  • the bottle body in horizontal section has a cross-section rectangular basic shape and has on its upper side a closed by a cover bottle neck.
  • two connection points are provided, one of which is provided a connection point for filling the bottle body with blood plasma and the other connection point of the venting and sampling is used.
  • a lid can be fastened to protect the connection points. This has two slots, which serve the implementation of fixed at the connection points hoses.
  • the lid is in a position where the tubing passes unhindered through the slots. After completion of the plasma donation, the tubes are cut off and welded. To fix the free ends of the cut tubes, the lid is rotated, pulling the free ends into the lid.
  • Object of the present invention is therefore to design a blood plasma collection bottle made of plastic for the storage of plasma in the frozen state of the type mentioned so that their handling is improved.
  • the operability is simplified and the dimensional stability can be increased.
  • a sterile filter with a hydrophobic layer is provided.
  • the sterile filter may comprise exclusively a hydrophobic layer or may also comprise, in addition to the hydrophobic layer, a thin hydrophilic layer which is arranged on the blood plasma-facing side of the sterile filter.
  • a connection point is designed such that it serves to fill the bottle body with blood plasma and to take the sample.
  • an L-shaped connector is provided, whose one connector leg is directed towards the bottleneck.
  • the other connection piece is used only for venting when filling with blood plasma or the ventilation during sampling, so that both processes can be carried out easily.
  • This connection piece is equipped with a preferably hydrophobic sterile filter. This can be inserted in the connection piece. Hydrophobic materials are preferable to hydrophilic materials for a sterile filter as they better retain bacteria.
  • hydrophobic materials are self-swelling on liquid contact, they are particularly suitable for the simple design of filters for blood plasma collection bottles, as they allow a sterile aeration of the bottle during filling, but at the withdrawal of the blood plasma cause a tight closure of the bottle.
  • conventional closures such as ball, needle or duckbill valves (duckbills) additionally require an upstream sterile antibacterial filter to ensure sterility during filling.
  • the L-shaped connectors are permanently attached to the connecting piece.
  • the connectors may be glued or welded to the spigot.
  • they are non-detachable and self-sealingly fixed to the connecting piece by means of a latching connection.
  • corresponding sealing surfaces can be formed on the connection piece and the L-shaped connectors, which are connected to each other especially under pressure come into contact when the L-shaped connectors are fixed to the connection piece.
  • the sealing surfaces may be provided, for example, at the upper edge of the connecting piece and a corresponding annular surface on the inside of the connector.
  • a sample tube or pilot tube is usually used for sampling.
  • the tube carries at least one pilot bag at its end, the pilot bag having a vent opening in which an at least partially hydrophobic frit is provided.
  • the frit can also be constructed from a combination of hydrophilic and hydrophobic material.
  • the sampling takes place in a simple manner in that the blood plasma collection container is tilted so that liquid flows from the container into the pilot bag. Subsequently, the pilot bag is sealed by its container-side end is welded. Furthermore, the vent is closed. This is preferably formed in a tubular Absch doende the pilot bag, in which also the at least partially hydrophobic frit is positioned, so that the vent opening can be closed by welding the Absch spaendes.
  • pilot bags are connected to the hose of the connection point for the venting and sampling via a corresponding, in particular Y-shaped connecting hose.
  • a connection point serves both the filling of the bottle body with blood plasma and the sampling
  • a lid can be fixed or fixable to the bottleneck and in particular to a cover flap closing the top of the bottle. This is designed such that it engages over the bottle neck protruding portions of the tubes in the fixed state and so positioned.
  • the cover can be designed so that it overlaps in the fixed state, the connection points and also protects from access from the outside.
  • the cover has the connectors / tubes associated and open towards the lid bottom recesses, which engage with the projecting over the bottle neck tube sections and are penetrated by these, when the lid is fixed to the bottle neck.
  • the lid may have on the inside holding webs, which engage over the long connector legs / hose sections and position when the lid is fixed to the bottle neck.
  • a latching mechanism is provided, via which the lid is fixed to the bottle neck and in particular the cover plate when the lid is pressed onto the bottleneck from above.
  • the latching mechanism according to a further aspect of the invention, a first detent position, in which the lid can be released again from the bottle neck, and a second detent position, in which the lid is further pressed onto the bottle neck than in the first detent position and in the prevents the lid from being detached from the neck of the bottle will be on.
  • the cover in the delivery state is releasably attached to the bottle neck, ie it is locked in the upper, first latching point. This makes it possible to detach the lid for filling the blood plasma collection bottle and then welding off the connectors from the bottleneck. After welding off the lid can then be finally fixed to the bottle neck by being brought into the second detent position in which a release is no longer possible.
  • latching noses are formed on the lower, open edge of the lid, which engage when pressing the lid on the bottleneck with a retaining web formed on the bottleneck and in particular the outer edge region of the cover, are elastically expanded and at resiliently spring back further impressions and engage behind the retaining web to produce the first detent position.
  • a latching opening and / or at least one latching notch may be formed in the web, in which engage receiving side provided in the second detent locking elements.
  • retaining elements in particular retaining clips for the detachable attachment of test tubes, are provided on the cover and in particular on the top side of the cover. This embodiment offers the possibility to deliver the sample tubes as a unit with the blood plasma collection bottle.
  • the side surfaces of the bottle body can each define a flat or slightly inwardly curved region, followed by rounded areas to the end surfaces. It has been shown that bottle bodies shaped in this way are particularly dimensionally stable. This is especially true when the areas are slightly curved inward, with the dome having a maximum depth of 2mm, especially 1.5mm from the edges of the dome. The inward curvature a kind of bias is achieved, which counteracts buckling of the bottle body during filling.
  • the stability of the bottle is further increased when the flat or slightly inwardly curved portions have a hexagonal shape, the bases are at the transition areas of the side surfaces to the top and bottom of the bottle body and preferably such hexagonal evenly designed that the between the bases lying corners are positioned approximately at the central height of the bottle body.
  • the bottle body then has a shape obtained by flattening an oval or round body, in which case the sides of the hexagonal faces lying between the bases are slightly rounded.
  • the flat or slightly inwardly curved areas may have a round, in particular oval or elliptical shape such that the lying between the bases horizontal symmetry axes are positioned approximately at the central height of the bottle body.
  • the bottle body may include a plurality of stiffening beads that extend around the bottle body and are preferably positioned to function, at least in part, as a level indicator.
  • a total of four stiffening beads may be formed on the bottle body, wherein in particular two stiffening beads are provided on the upper bottle body half and two stiffening beads in the lower bottle body half.
  • the blood plasma collection bottle is made of plastic, in particular polyethylene (PE) and has a bottle body 1, which has a cross section of rectangular basic shape in horizontal section and carries on its upper side a bottle neck 2 with a top provided cover plate 2a.
  • PE polyethylene
  • the side surfaces of the bottle body 1 each define a planar region 3 of elliptical shape, wherein the horizontal axes of symmetry E lying between the bases 3a, 3b are positioned approximately at the central height of the bottle body 1.
  • On the flat side surfaces of the bottle body 1 close to the end faces, which have a rounded shape.
  • the bottle body 1 has a shape that is obtained when flattening a base round shape. It can not be seen in the drawing that the flat areas 3 can also be curved slightly inwards, the curvature in the center of the elliptical area 3 having a depth of approximately 1.5 mm with respect to the edges of the elliptical area 3. By this configuration, a kind of bias is achieved, which counteracts buckling of the bottle body 1 when filling with blood plasma. Alternatively, the flat portion 3 may also have an oval shape.
  • the bottle body 1 has a total of four stiffening beads 5, which extend around the bottle body 1, wherein a stiffening bead 5 in the upper bottle body half and three stiffening beads 5 are provided in the lower bottle body half.
  • the upper stiffening bead 5 can act as Brown Bushnan Garnier
  • a blood plasma collection bottle is shown, the bottle body having four stiffening beads 5, which extend around the bottle body 1, wherein two stiffening beads 5 are provided in the upper bottle body half and two stiffening beads 5 in the lower bottle body half.
  • the upper stiffening bead 5 can act as a level indicator.
  • flat areas 3 of hexagonal shape are formed on the bottle body, the bases 3a, 3b lie at the transition areas of the side surfaces to the top and bottom of the bottle body 1. In this case, the corners E lying between the base sides 3a, 3b are positioned approximately at the central height of the bottle body 1.
  • the sides 3c, 3d, 3e, 3f of the hexagonal areas located between the bases 3a, 3b are slightly rounded off.
  • three adjustable feet 4 are provided, by which it is ensured that the flat blood plasma collection bottle can be stably placed.
  • connection points 7a, 7b are provided on opposite sides of the bottle neck 2 and laterally spaced therefrom, one of which 7a serves to fill the bottle body 1 with blood plasma and the other connection point 7b serves for venting and sampling.
  • connection points 7a, 7b firmly connected to the bottle body 1 connecting piece 8 are provided, on which L-shaped connectors 9 are held insoluble.
  • the bottle body 1 may have two connection points 7c, 7d, of which one connection point 7c serves both for filling the bottle body 1 with blood plasma and for sampling.
  • one connection point 7c serves both for filling the bottle body 1 with blood plasma and for sampling.
  • an attachment piece 8 of the connection point 7c serving for filling and sampling is provided with an L-shaped connector 9.
  • the connecting piece 8 of the other connection point 7d is used only for loading and bleeding the bottle body 1.
  • a non-illustrated hydrophobic sterile filter is housed.
  • the sterile filter may have, in addition to a hydrophobic layer 8a, a thin hydrophilic layer 8b on the blood plasma facing side
  • the L-shaped connectors 9 are fixed to the connecting piece 8 by a latching mechanism.
  • a latching mechanism for this purpose, in the lower end region of the connecting piece 8 an outwardly projecting latching shoulder 8a and the inside of the connectors 9 a corresponding latching lug 9a is formed, which engages the latching shoulder 8a latching when a connector 9 is pressed onto a connecting piece 8.
  • FIG. 11 shown that on the inside of the connectors 9 each have a sealing surface 9b is formed, which comes to a sealing surface 8b at the upper edge of the corresponding connecting piece 8 sealingly and under pressure in abutment when the connector 9 is fixed to the connecting piece 8.
  • hoses 10 are attached at the points away from the connecting piece 8 at the points away from the connecting piece 8 at the points away from the connecting piece 8 connector legs hoses 10 are attached.
  • the arrangement is made such that the connector legs pointing away from the connecting piece 8 are directed to the bottle neck 2, so that the tubes 10 held thereon extend over the cover plate 2a of the bottle neck 2.
  • the hoses 10 are shown in the solvesch doten state, in which the Hose ends are located directly above the cover plate 2a. In the unswelded state, the tubes 10 are significantly longer.
  • a lid 11 is fixed on the cover plate 2a of the bottle neck 2, a lid 11 is fixed. This is designed such that it overlaps in the fixed state over the bottle neck 2 projecting portions of the tubes 10 and protects against access from the outside. Specifically, the lid 11 the hoses 10 associated and the lid bottom side open, slot-shaped recesses 12, which come into engagement with the projecting over the bottle neck 2 tube sections and are penetrated by these when the lid 11 is fixed to the bottle neck 2. Like in the FIG. 12 is shown, the lid 11 may also be formed so wide that it surrounds the L-shaped connectors 9.
  • the latching mechanism comprises a first detent position, in which the lid 11 can be released again from the bottle neck 2, and a second detent position, in which a release of the lid 11 of the bottle neck 2 is substantially no longer possible.
  • latching lugs 13 are formed on the lower, open lid edge, which come when depressing the lid 11 on the bottle neck 2 with the outer edge region of the cover plate 2 engage, are elastically expanded and elastically spring back on further depression of the lid 11 and to produce the first Detent position engage behind the cover plate 2a.
  • an upright projecting web 14 is formed on the upper side of the cover plate 2a and a receptacle 15 corresponding to the web 14 is formed on the inner side of the cover, which engage with one another when the cover 11 is pressed onto the bottle neck 2.
  • a round latching opening 16 is formed on the web 14, with which a receiving side provided latching tooth 17a engages when the lid 11 is pushed beyond the first detent position on the bottle neck 2 in the second detent position.
  • the engagement region between the latching opening 16a and the latching tooth 17a is not accessible from the outside, so that a release of this connection is prevented.
  • a lateral detent groove 16b is formed, with which a receiving side provided latching tooth 17b engages when the lid 11 is pressed onto the bottle neck 2.
  • the lid 11 carries at its top retaining clips 18 for releasably attaching sample tube 19.
  • the lid 11 In the delivery state, the lid 11 is fixed on the bottleneck 2 via the upper, first latching point. After the blood plasma collection bottle has been filled in a conventional manner, the lid 11 is removed, and then the tubes 10 are welded so that they fit under the lid 11. After welding, the lid 11 is again attached to the bottle neck 2 and thereby depressed so far that a fixation on the second detent position takes place, so that a renewed removal of the lid 11 is prevented. Thus, the hoses 10 are inaccessible for subsequent manipulation.
  • FIG. 13 an embodiment is shown in which instead of sampling tubes two pilot bags 20 are connected to the sampler serving connector 9.
  • the hose 10 which is connected to the free end of the L-shaped connector 9 at the sampling point serving connection 7 b, connected at its free end via a Y-shaped connecting hose 21 with the two pilot bags 20.
  • the pilot bags 20 have a hose-like Absch usageende 22 with a vent opening 23, wherein in the Absch bulkende 22 a hydrophobic frit 24 is housed.
  • the frit 24 may also comprise a combination of hydrophobic and hydrophilic material.
  • the sampling is carried out in a simple manner in that the blood plasma collection container is tilted, so that liquid flows from the bottle body 1 in the two pilot bags 20 until the hydrophobic frit 24 closes. Subsequently, the pilot bags 20 are welded at their two Absch doenden 22.
  • Y-shaped connecting tube 21 may also be provided a connecting tube with three or more ports, the other ports then form ventilation openings in which hydrophobic sterile filter or frits are provided, via which air can escape from the bottle body 1 during filling of the blood plasma collection container ,

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  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Fluid Mechanics (AREA)
  • Hematology (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
EP16168073.1A 2015-05-06 2016-05-03 Bouteille de collecte de plasma sanguin Withdrawn EP3090720A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE202015102323.5U DE202015102323U1 (de) 2015-05-06 2015-05-06 Blutplasmasammelflasche

Publications (1)

Publication Number Publication Date
EP3090720A1 true EP3090720A1 (fr) 2016-11-09

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ID=55968911

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Application Number Title Priority Date Filing Date
EP16168073.1A Withdrawn EP3090720A1 (fr) 2015-05-06 2016-05-03 Bouteille de collecte de plasma sanguin

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EP (1) EP3090720A1 (fr)
DE (1) DE202015102323U1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108504553A (zh) * 2018-05-22 2018-09-07 中国农业科学院兰州畜牧与兽药研究所 一种便于取样的细菌培养瓶

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0379047A1 (fr) * 1989-01-19 1990-07-25 Abbott Laboratories Ensemble de délivrance entérale avec filtre de germes intérieur
US5125522A (en) * 1988-12-22 1992-06-30 Abbott Laboratories Enteral delivery set assembly
DE202007012912U1 (de) 2007-09-14 2007-12-06 Heinz Meise Gmbh Blutplasma-Behälter
EP2433610A2 (fr) * 2010-09-22 2012-03-28 Deutsche Gesellschaft für Humanplasma mbH Bouteille de collecte de plasma sanguin
FR2980971A1 (fr) * 2011-10-11 2013-04-12 Cair L G L Bouchon et systeme de nutrition enterale
WO2014095351A1 (fr) * 2012-12-21 2014-06-26 Fresenius Kabi Deutschland Gmbh Adaptateur pour bouteilles de lait
EP2782543A1 (fr) * 2011-11-22 2014-10-01 Deutsche Gesellschaft für Humanplasma mbH Flacon de collecte de plasma sanguin

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5125522A (en) * 1988-12-22 1992-06-30 Abbott Laboratories Enteral delivery set assembly
EP0379047A1 (fr) * 1989-01-19 1990-07-25 Abbott Laboratories Ensemble de délivrance entérale avec filtre de germes intérieur
DE202007012912U1 (de) 2007-09-14 2007-12-06 Heinz Meise Gmbh Blutplasma-Behälter
EP2433610A2 (fr) * 2010-09-22 2012-03-28 Deutsche Gesellschaft für Humanplasma mbH Bouteille de collecte de plasma sanguin
FR2980971A1 (fr) * 2011-10-11 2013-04-12 Cair L G L Bouchon et systeme de nutrition enterale
EP2782543A1 (fr) * 2011-11-22 2014-10-01 Deutsche Gesellschaft für Humanplasma mbH Flacon de collecte de plasma sanguin
WO2014095351A1 (fr) * 2012-12-21 2014-06-26 Fresenius Kabi Deutschland Gmbh Adaptateur pour bouteilles de lait

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Publication number Publication date
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